LOCUS       NM_001013745            1846 bp    mRNA    linear   ROD 28-JAN-2025
DEFINITION  Mus musculus zinc finger protein 57 (Zfp57), transcript variant 1,
            mRNA.
ACCESSION   NM_001013745
VERSION     NM_001013745.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1846)
  AUTHORS   Zhao,J. and Zhao,J.
  TITLE     Maternal and zygotic ZFP57 regulate coronary vascular formation and
            myocardium maturation in mouse embryo
  JOURNAL   Dev Dyn 253 (1), 144-156 (2024)
   PUBMED   36004502
  REMARK    GeneRIF: Maternal and zygotic ZFP57 regulate coronary vascular
            formation and myocardium maturation in mouse embryo.
REFERENCE   2  (bases 1 to 1846)
  AUTHORS   Xu,Z., Shi,J., Zhang,Y., Liu,Y., Zhao,J., Chen,Q., Song,C.,
            Geng,S., Xie,W., Wu,F., Bai,Y., Yang,Y. and Li,X.
  TITLE     Zfp57 Exerts Maternal and Sexually Dimorphic Effects on Genomic
            Imprinting
  JOURNAL   Front Cell Dev Biol 10, 784128 (2022)
   PUBMED   35252168
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1846)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1846)
  AUTHORS   Acurzio,B., Verma,A., Polito,A., Giaccari,C., Cecere,F.,
            Fioriniello,S., Della Ragione,F., Fico,A., Cerrato,F., Angelini,C.,
            Feil,R. and Riccio,A.
  TITLE     Zfp57 inactivation illustrates the role of ICR methylation in
            imprinted gene expression during neural differentiation of mouse
            ESCs
  JOURNAL   Sci Rep 11 (1), 13802 (2021)
   PUBMED   34226608
  REMARK    GeneRIF: Zfp57 inactivation illustrates the role of ICR methylation
            in imprinted gene expression during neural differentiation of mouse
            ESCs.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1846)
  AUTHORS   Jiang,W., Shi,J., Zhao,J., Wang,Q., Cong,D., Chen,F., Zhang,Y.,
            Liu,Y., Zhao,J., Chen,Q., Gu,L., Zhou,W., Wang,C., Fang,Z.,
            Geng,S., Xie,W., Chen,L.N., Yang,Y., Bai,Y., Lin,H. and Li,X.
  TITLE     ZFP57 dictates allelic expression switch of target imprinted genes
  JOURNAL   Proc Natl Acad Sci U S A 118 (5) (2021)
   PUBMED   33500348
REFERENCE   6  (bases 1 to 1846)
  AUTHORS   Li,X., Ito,M., Zhou,F., Youngson,N., Zuo,X., Leder,P. and
            Ferguson-Smith,A.C.
  TITLE     A maternal-zygotic effect gene, Zfp57, maintains both maternal and
            paternal imprints
  JOURNAL   Dev Cell 15 (4), 547-557 (2008)
   PUBMED   18854139
  REMARK    GeneRIF: Zpf57 maintains both maternal and paternal genomic
            imprints.
REFERENCE   7  (bases 1 to 1846)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
REFERENCE   8  (bases 1 to 1846)
  AUTHORS   Alonso,M.B., Zoidl,G., Taveggia,C., Bosse,F., Zoidl,C., Rahman,M.,
            Parmantier,E., Dean,C.H., Harris,B.S., Wrabetz,L., Muller,H.W.,
            Jessen,K.R. and Mirsky,R.
  TITLE     Identification and characterization of ZFP-57, a novel zinc finger
            transcription factor in the mammalian peripheral nervous system
  JOURNAL   J Biol Chem 279 (24), 25653-25664 (2004)
   PUBMED   15070898
REFERENCE   9  (bases 1 to 1846)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   10 (bases 1 to 1846)
  AUTHORS   Okazaki,S., Tanase,S., Choudhury,B.K., Setoyama,K., Miura,R.,
            Ogawa,M. and Setoyama,C.
  TITLE     A novel nuclear protein with zinc fingers down-regulated during
            early mammalian cell differentiation
  JOURNAL   J Biol Chem 269 (9), 6900-6907 (1994)
   PUBMED   8120052
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CF731693.1, BC052028.1 and CR956641.9.
            
            On Dec 9, 2009 this sequence version replaced NM_001013745.1.
            
            Transcript Variant: This variant (1) represents the predominant
            transcript and encodes the longer isoform (1). Variants 1 and 2
            encode the same isoform.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK145368.1, AK136241.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-536               CF731693.1         2-537
            537-1749            BC052028.1         704-1916
            1750-1846           CR956641.9         7270-7366           c
FEATURES             Location/Qualifiers
     source          1..1846
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 19.16 cM"
     gene            1..1846
                     /gene="Zfp57"
                     /gene_synonym="G19; Zfp-57"
                     /note="zinc finger protein 57"
                     /db_xref="GeneID:22715"
                     /db_xref="MGI:MGI:99204"
     exon            1..253
                     /gene="Zfp57"
                     /gene_synonym="G19; Zfp-57"
                     /inference="alignment:Splign:2.1.0"
     exon            254..283
                     /gene="Zfp57"
                     /gene_synonym="G19; Zfp-57"
                     /inference="alignment:Splign:2.1.0"
     exon            284..390
                     /gene="Zfp57"
                     /gene_synonym="G19; Zfp-57"
                     /inference="alignment:Splign:2.1.0"
     CDS             373..1638
                     /gene="Zfp57"
                     /gene_synonym="G19; Zfp-57"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="zinc finger protein 57 isoform 1"
                     /protein_id="NP_001013767.1"
                     /db_xref="CCDS:CCDS28733.1"
                     /db_xref="GeneID:22715"
                     /db_xref="MGI:MGI:99204"
                     /translation="MAARKQSSQPSRTPVSYEDVAVSFTQEEWEYLTSTQKTLYQKVM
                     SETFKNLTFVGSKKKPQEPSSDLQDKNEEQEKSSSCTGVFKGGPFFFCLTCGKCFKKN
                     TFLFNHQFPVRSRRLAVTNPQSRKGKGYKAQHRGERPFFCNFCGKTYRDASGLSRHRR
                     AHLGYRPRSCPECGKCFRDQSEVNRHLKVHQNKPAASNQAGNQASNQRLKSRVPPTTP
                     RSQAPALKYVKVIQGPVARAKARNSGASTLNVRSNSITVVRSREKISCPYCHITFTMR
                     TCLLTHLKIHFRRQPNQHFCCKESAHSSNTLRMQKIYTCPVCDSSFRGKESLLDHLCC
                     QRPIRFSKCWEILGHLLGYLHEPVVLGNIFKVRDSSGKRMESRRRRRKRACTENPETE
                     GLSGKGRVAPWEMEGATSPESPVTEEDSD"
     exon            391..535
                     /gene="Zfp57"
                     /gene_synonym="G19; Zfp-57"
                     /inference="alignment:Splign:2.1.0"
     exon            536..1846
                     /gene="Zfp57"
                     /gene_synonym="G19; Zfp-57"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1708..1713
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp57"
                     /gene_synonym="G19; Zfp-57"
                     /note="hexamer: AATACA"
     regulatory      1723..1728
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp57"
                     /gene_synonym="G19; Zfp-57"
                     /note="hexamer: ACTAAA"
     polyA_site      1729
                     /gene="Zfp57"
                     /gene_synonym="G19; Zfp-57"
                     /note="major polyA site"
     polyA_site      1753
                     /gene="Zfp57"
                     /gene_synonym="G19; Zfp-57"
ORIGIN      
        1 aaatttctga ccttggcaga cagccacttg agatgtgtta cctgcggacg gagcagaacg
       61 gaagcagagg gacaaagtag cggattcctg acttctggca agggcccctt cctgggtttc
      121 acgccgctgc gttctggtcg aggctggaac gcgcgcccag ccctttgtgt ggctgtggtc
      181 cgaggctacg gctcagaagc cgagcgctgg gaacggcagg actgccgagc ctcaagtagg
      241 gctgtcgagc gcgggctcct gcaccaggaa agaacaatca gagatttcta gaagtgggca
      301 ccaacaaatt gtggctagaa gcagtctgga atagaagtca aacgcctagg accagcctgg
      361 cattaccaaa caatggcagc taggaaacag tcttcccagc catccaggac accagtcagt
      421 tatgaggacg tggcagtgtc tttcacccag gaagaatggg aatatcttac ttctacacag
      481 aagacccttt accagaaagt gatgtcagaa accttcaaga acctgacatt tgtcggaagc
      541 aagaagaaac ctcaagaacc tagctcagat ctgcaagata agaacgagga gcaggagaag
      601 tcctccagtt gcacaggggt attcaaaggt ggaccattct ttttctgtct gacctgtggc
      661 aaatgtttca aaaagaacac cttcctcttt aatcaccagt ttcctgtgag gtcccggagg
      721 ctggcagtca caaatccaca aagccgcaaa ggcaagggct acaaggctca gcatcgtgga
      781 gagaggcctt tcttttgtaa tttctgtggc aagacttacc gtgatgcttc tggactgagc
      841 cgtcaccgac gtgctcattt aggttatagg ccccgttcat gccctgagtg tggaaagtgt
      901 ttccgggatc agtctgaggt caaccgtcac ctgaaggtac accaaaacaa gccagcagct
      961 agcaaccagg ctggcaacca ggctagcaac cagaggctga agagtagggt tccacctaca
     1021 acacctagat cccaagcgcc cgccctcaag tatgtgaaag tgatccaggg accagtggcc
     1081 agggctaagg cacggaacag cggagcctcg accctgaatg tcagatccaa ctctattaca
     1141 gtggtccgtt caagagaaaa gatctcttgt ccctattgtc acataacgtt taccatgaga
     1201 acctgtctct taacccacct caagatccac ttcagacgtc aacccaacca gcacttctgc
     1261 tgcaaagagt cggcccactc atccaacaca ctcagaatgc aaaagatcta cacttgcccc
     1321 gtctgtgaca gctcctttag gggaaaggag agcctgctgg atcacttgtg ctgccaaaga
     1381 ccaatcagat tcagtaaatg ctgggaaatc ctgggtcatt tgctcggcta tcttcatgaa
     1441 cccgtggtgc tgggaaatat ttttaaagta agggactcct cgggaaagag gatggaatcc
     1501 aggaggagaa gacggaaacg tgcctgcact gagaatcctg aaacagaagg cctgtctggg
     1561 aaaggtaggg tggctccgtg ggaaatggag ggtgccacca gccctgagag tcctgtgaca
     1621 gaagaagatt cggactgatt tctgacttca cacctaccca tgcacgacac cccccacccc
     1681 caccccttac ccccacccca caaaataaat acaattttta aaactaaaag aaggggaggg
     1741 gaggtcaaac tgaggtcttt gtatttgttt ttttcctgaa gacttgacct ctgccatcag
     1801 gaggcttgaa caggagagaa gtggatgatg aaggaaagag acaagg
//
