LOCUS       NM_001361053            6418 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus zinc finger protein 532 (Zfp532), transcript variant
            1, mRNA.
ACCESSION   NM_001361053 XM_011246950
VERSION     NM_001361053.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6418)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 6418)
  AUTHORS   Liang,G.H., Luo,Y.N., Wei,R.Z., Yin,J.Y., Qin,Z.L., Lu,L.L. and
            Ma,W.H.
  TITLE     CircZNF532 knockdown protects retinal pigment epithelial cells
            against high glucose-induced apoptosis and pyroptosis by regulating
            the miR-20b-5p/STAT3 axis
  JOURNAL   J Diabetes Investig 13 (5), 781-795 (2022)
   PUBMED   34839589
  REMARK    GeneRIF: CircZNF532 knockdown protects retinal pigment epithelial
            cells against high glucose-induced apoptosis and pyroptosis by
            regulating the miR-20b-5p/STAT3 axis.
REFERENCE   3  (bases 1 to 6418)
  AUTHORS   Wiese,C.B., Ireland,S., Fleming,N.L., Yu,J., Valerius,M.T.,
            Georgas,K., Chiu,H.S., Brennan,J., Armstrong,J., Little,M.H.,
            McMahon,A.P. and Southard-Smith,E.M.
  TITLE     A genome-wide screen to identify transcription factors expressed in
            pelvic Ganglia of the lower urinary tract
  JOURNAL   Front Neurosci 6, 130 (2012)
   PUBMED   22988430
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 6418)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: III. the complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (4), 167-180 (2003)
   PUBMED   14621295
REFERENCE   5  (bases 1 to 6418)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC132307.5 and AC124578.4.
            
            On Feb 27, 2018 this sequence version replaced XM_011246950.2.
            
            Transcript Variant: This variant (1) represents the longest
            transcript. Variants 1, 2 and 3 encode the same protein.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660821.78507.1,
                                           SRR9219382.1489.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-392               AC132307.5         59832-60223         c
            393-502             AC132307.5         59635-59744         c
            503-2853            AC132307.5         17307-19657         c
            2854-3035           AC132307.5         3710-3891           c
            3036-3212           AC124578.4         1650-1826
            3213-3375           AC124578.4         9017-9179
            3376-3657           AC124578.4         13808-14089
            3658-3770           AC124578.4         40352-40464
            3771-3936           AC124578.4         42982-43147
            3937-6418           AC124578.4         44419-46900
FEATURES             Location/Qualifiers
     source          1..6418
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 38.91 cM"
     gene            1..6418
                     /gene="Zfp532"
                     /gene_synonym="C530030I18Rik; mKIAA1629; Znf532"
                     /note="zinc finger protein 532"
                     /db_xref="GeneID:328977"
                     /db_xref="MGI:MGI:3036282"
     exon            1..392
                     /gene="Zfp532"
                     /gene_synonym="C530030I18Rik; mKIAA1629; Znf532"
                     /inference="alignment:Splign:2.1.0"
     exon            393..502
                     /gene="Zfp532"
                     /gene_synonym="C530030I18Rik; mKIAA1629; Znf532"
                     /inference="alignment:Splign:2.1.0"
     exon            503..2853
                     /gene="Zfp532"
                     /gene_synonym="C530030I18Rik; mKIAA1629; Znf532"
                     /inference="alignment:Splign:2.1.0"
     CDS             517..4431
                     /gene="Zfp532"
                     /gene_synonym="C530030I18Rik; mKIAA1629; Znf532"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="zinc finger protein 532 isoform 1"
                     /protein_id="NP_001347982.1"
                     /db_xref="CCDS:CCDS89265.1"
                     /db_xref="GeneID:328977"
                     /db_xref="MGI:MGI:3036282"
                     /translation="MTMGDMKTPDFDDLLAAFDIPDMVDPKAAIESGHDDHESHIKQN
                     AHVDDDSHTPSSSDVGVSVIVKNVRNIDSSEGVEKDGHNPTGNGLHNGFLTASSLDSY
                     GKDGAKSLKGDTPASEVTLKDPAFSQFSPISSAEEFEDDEKIEVDDPPDKEEARAGFR
                     SNVLTGSAPQQDFDKLKALGGENSSKTGVSTSGHTDKNKVKREAESNSITLSVYEPFK
                     VRKAEDKLKENSEKMLESRVLDGKPSSEKSDSGIAAAASSKTKPSSKLSSCIAAIAAL
                     SAKKAASDSCKEPVANSREASPLPKEVNDSPKAADKSPESQNLIDGTKKASLKPSDSP
                     RSVSSENSSKGSPSSPVGSTPAIPKVRIKTIKTSSGEIKRTVTRVLPEVDLDSGKKPS
                     EQAASVMASVTSLLSSSASATVLSSPPRAPLQTAMVTSAVSSAELTPKQVTIKPVATA
                     FLPVSAVKTAGSQVINLKLANNTTVKATVISAASVQSASSAIIKAANAIQQQTVVVPA
                     SSLANAKLVPKTVHLANLNLLPQGAQATSELRQVLTKPQQQIKQAIINAAASQPPKKV
                     SRVQVVSSLQSSVVEAFNKVLSSVNPVPVYTPNLSPPANAGITLPMRGYKCLECGDAF
                     ALEKSLSQHYDRRSVRIEVTCNHCTKNLVFYNKCSLLSHARGHKEKGVVMQCSHLILK
                     PVPADQMIVPPSSNTAASTLQSSVGAATHTVPKVQPGIAGAVISAPASTPMSPAMPLD
                     EDPSKLCRHSLKCLECNEVFQDEPSLATHFQHAADTSGQKTCTVCQMLLPNQCSYASH
                     QRIHQHKSPYTCPECGAICRSVHFQNHITKNCLHYTRRVGFRCVHCNVVYSDVAALKS
                     HIQGSHCEVFYKCPICPMAFKSAPSTHSHAYTQHPGVKIGEPKIIYKCSMCDTVFTLQ
                     TLLYRHFDQHTDNQKVSVFKCPDCSLLYAQKQLMMDHIKSMHGTLKSIEGPPNLGINL
                     PLSVKPATQNSANHSREDAKSVNGKEKLEKKSPSPAKKSTEPKKMASLGWTCWECDRL
                     FTQRDVYLSHMRKEHGKQMKKHPCRQCDKSFSSSHSLCRHNRIKHKGIRKVYACSHCP
                     DSRRTFTKRLMLERHIQLMHGIKDPDVKELSDDAGDVTNDEEEEAEIKEDAKVPSPKR
                     KLEEPVLEFRPPRGAITQPLKKLKINVFKVHKCAVCGFTTENLLQFHEHIPQHRSDGS
                     SHQCRECGLCYTSHGSLARHLFIVHKLKEPQPVSKQNGAGEDSQQENKPSPEDEAAEG
                     AASDRKCKVCAKTFETEAALNTHMRTHGMAFIKSKRMSSAEK"
     exon            2854..3035
                     /gene="Zfp532"
                     /gene_synonym="C530030I18Rik; mKIAA1629; Znf532"
                     /inference="alignment:Splign:2.1.0"
     exon            3036..3212
                     /gene="Zfp532"
                     /gene_synonym="C530030I18Rik; mKIAA1629; Znf532"
                     /inference="alignment:Splign:2.1.0"
     exon            3213..3375
                     /gene="Zfp532"
                     /gene_synonym="C530030I18Rik; mKIAA1629; Znf532"
                     /inference="alignment:Splign:2.1.0"
     exon            3376..3657
                     /gene="Zfp532"
                     /gene_synonym="C530030I18Rik; mKIAA1629; Znf532"
                     /inference="alignment:Splign:2.1.0"
     exon            3658..3770
                     /gene="Zfp532"
                     /gene_synonym="C530030I18Rik; mKIAA1629; Znf532"
                     /inference="alignment:Splign:2.1.0"
     exon            3771..3936
                     /gene="Zfp532"
                     /gene_synonym="C530030I18Rik; mKIAA1629; Znf532"
                     /inference="alignment:Splign:2.1.0"
     exon            3937..6418
                     /gene="Zfp532"
                     /gene_synonym="C530030I18Rik; mKIAA1629; Znf532"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5890..5895
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp532"
                     /gene_synonym="C530030I18Rik; mKIAA1629; Znf532"
                     /note="hexamer: AATAAA"
     polyA_site      5916
                     /gene="Zfp532"
                     /gene_synonym="C530030I18Rik; mKIAA1629; Znf532"
                     /note="major polyA site"
ORIGIN      
        1 ctaaaagagc ctgtgtagag atgattgggg ggaaaggtgc acgtttgcag gctctgagat
       61 ttcttgggct tttcctgcct tttttttctc ttttgcttaa gggatggaca aggagctgag
      121 atttatagcc cttattaaag aaaaaaaaat atgtgcctta ttagggtggg gacacttggt
      181 acaatctctc tctccttttc tctgtgtttt tatggaaaca aaactagaat gaactgatgg
      241 gtttgtaagg tagtttgttg ctagagaatg ttgctgtgca tgcttttttt ttttccctct
      301 ctcttgcagg ctgtgttctg ttttgggctt ttccttttag aagctactaa gagggtgttg
      361 gggatacttg ggactgttat gaaggccaaa aggcctggtg actggggctg cttttaaccc
      421 tttcctattt gcagagaatg caactgtgtg acagtaactg aacactgggc caaagtcttt
      481 tcaaaaggtc aaggttcaca agaactgatc aaattcatga ccatggggga tatgaagacc
      541 ccagactttg atgacctctt ggcagcattt gacataccag atatggtcga tcccaaagca
      601 gcgattgagt ccggacacga tgaccatgag agccacatta agcagaatgc tcacgtggat
      661 gacgactctc acaccccatc atcctcagac gtcggcgtca gtgtgattgt gaagaatgtc
      721 cgcaacatcg actcctccga gggggtggaa aaagatggcc acaatcccac aggcaatggt
      781 ttgcataatg ggttcctcac ggcatcctct cttgacagct atggtaagga tggagccaag
      841 tccttaaaag gagacacacc tgcctcggag gtgactctta aggacccggc attcagccag
      901 ttcagcccca tctccagcgc cgaggagttt gaggacgatg agaagataga ggtggacgac
      961 ccgcctgata aggaggaggc gcgggccggt ttcagatcga atgtgctgac gggctcagca
     1021 ccccagcagg acttcgacaa actgaaggca cttggagggg aaaactccag caagactgga
     1081 gtctctacat caggccacac ggataaaaac aaggtcaaga gggaggcaga aagcaattct
     1141 ataaccctga gtgtttatga gccatttaag gtcagaaaag cagaggataa gttgaaggag
     1201 aactctgaga agatgcttga gagcagggtc cttgacggga agccgagctc cgagaagagc
     1261 gactccggca tcgctgctgc cgcatcttcc aaaacgaagc cgtcctccaa gctctcctcg
     1321 tgcatagcgg ccattgcggc gctcagcgct aaaaaggctg cgtccgactc ctgcaaagag
     1381 cctgtggcca actccaggga agcctccccg ttaccaaaag aagtgaatga cagtcccaaa
     1441 gctgccgaca agtctcccga gtcccagaat ctcatcgatg gcaccaagaa ggcctccctg
     1501 aagccatcag acagtcccag gagcgtatcc agtgagaaca gcagcaaagg gtcaccatcc
     1561 tcacccgtgg gctctacccc agccatcccc aaagtccgca tcaagaccat caagacatcg
     1621 tctggggaga tcaagaggac tgtgaccaga gtgctgccag aagtggacct ggactctgga
     1681 aagaagcctt ctgagcaggc agcgtccgtg atggcgtctg tgacatcact cctgtcatct
     1741 tcagcatcag ccacggtcct ctcctccccg cccagggcac ctctgcagac ggccatggtt
     1801 acaagtgcag tttcctctgc agagctgacc cccaaacagg tcaccatcaa gcccgtggcg
     1861 acagcttttc ttcccgtgtc tgccgtcaag acggcagggt ctcaagtcat caatctgaag
     1921 ctcgccaaca acacaacggt gaaagccacg gtcatatccg ccgcctctgt tcagagtgcc
     1981 agtagcgcca tcatcaaagc tgccaatgcc atccagcagc aaaccgttgt ggtgccggca
     2041 tccagcctgg ccaatgccaa actcgtgcca aagactgtgc accttgccaa ccttaacctt
     2101 ctgcctcagg gtgcccaggc cacctctgaa ctccgccaag tgctcaccaa acctcagcag
     2161 caaataaagc aggcaataat caatgcagcg gcctcgcagc cacctaagaa ggtgtctcgg
     2221 gtccaggtgg tgtcgtcctt gcagagttct gtggtggaag ctttcaacaa ggtgctgagc
     2281 agcgtcaacc cagtcccggt ttacaccccc aacctcagtc ctcctgccaa cgcagggatc
     2341 acgttaccga tgcgtgggta caagtgcttg gagtgcgggg acgcctttgc cctggagaag
     2401 agcctgagcc agcactacga caggcgaagc gtgcgcatcg aagtgacgtg caaccactgt
     2461 accaagaacc ttgtttttta caacaaatgc agcctccttt ctcacgcccg cgggcataag
     2521 gagaaaggcg tggtgatgca gtgctcccac ctgatcctaa agccggtccc ggcagaccag
     2581 atgatagttc ctccatccag caatactgct gcttccactc tgcagagctc tgtgggagct
     2641 gccacacaca ctgtcccaaa agtccagcct ggcatagccg gggcagttat ctcagctccg
     2701 gcaagcacac ccatgagccc agccatgccc ctagacgaag acccctccaa gctctgtaga
     2761 cacagtctca agtgtttgga gtgtaatgaa gtcttccagg atgagccgtc cctggccaca
     2821 catttccagc acgctgcaga caccagtgga caaaagactt gcactgtctg ccagatgctg
     2881 cttcctaacc agtgcagcta tgcgtcacac cagagaatcc atcagcacaa atctccctac
     2941 acctgccccg agtgcggggc catctgcagg tcggtgcact tccagaacca catcaccaag
     3001 aactgcctgc actacacgcg gagagttggt tttcgatgtg tacattgcaa tgttgtgtac
     3061 tctgatgtgg ctgcactgaa gtctcacatt caaggctctc actgtgaagt cttctacaag
     3121 tgccctatct gtccaatggc gtttaagtct gccccaagca cacattccca cgcctacacg
     3181 cagcatcctg gcgtcaagat aggagaacca aaaataatct ataagtgttc catgtgcgac
     3241 actgtgttca ctctgcaaac cttgctgtat cgccactttg accagcacac tgacaaccag
     3301 aaggtgtctg ttttcaagtg tccagactgt tctcttttat atgcccagaa gcaacttatg
     3361 atggaccata tcaagtctat gcatggaaca ttgaaaagta ttgaagggcc tccaaacttg
     3421 ggtataaact tgcctttgag cgttaagcct gcaactcaga attcagcaaa ccacagcaga
     3481 gaggatgcca agtccgtgaa tgggaaagag aaactggaaa agaagtctcc atctcctgca
     3541 aagaagtcca cagaacccaa gaagatggcc agtctcgggt ggacgtgttg ggagtgtgac
     3601 cgtctgttca cacagaggga tgtgtatctg tctcacatga ggaaagagca tgggaagcaa
     3661 atgaagaagc acccgtgccg ccagtgtgac aagtctttca gctcctccca cagcctgtgc
     3721 cgccacaatc gcatcaagca caaaggcatc aggaaagttt acgcctgctc gcactgccca
     3781 gactcccggc ggaccttcac caagcggctg atgctggaga ggcacataca gctgatgcac
     3841 gggatcaagg accctgatgt aaaagagctg agtgatgacg ctggtgatgt taccaacgat
     3901 gaggaggagg aggcggagat aaaggaggac gccaaggttc ccagtcccaa gcggaagttg
     3961 gaggagccgg ttttagagtt caggcctccc agaggagcca tcactcagcc actgaagaaa
     4021 ctgaaaatca atgtctttaa ggtccacaag tgtgccgtgt gtggcttcac caccgagaac
     4081 ctgctgcagt tccacgaaca catcccacag cacaggtcgg acggctcctc ccaccagtgc
     4141 cgggagtgtg gcctgtgcta cacgtcccac ggctccctgg ccaggcacct cttcatcgtg
     4201 cacaagctga aggagcctca gcccgtgtcc aagcagaacg gggctgggga agacagccag
     4261 caggagaaca agcccagccc tgaggacgag gccgccgagg gggcagcatc agacaggaag
     4321 tgcaaagtgt gcgccaagac ttttgaaacg gaagctgcct taaacacaca catgcggaca
     4381 catggcatgg ccttcatcaa atccaaaaga atgagttcag ctgaaaaata gccacagaac
     4441 ttccaggagg acaaccccta tccacatagg aatggagaat aagacgtttt tgttaccaaa
     4501 agttggcagt ataacaagag ttaccagtac cgtctaggct gtcgccacag actccctgtc
     4561 ctgccctctc acctctgcag atgtgtccct tcccataagt gttaaggcag tatttgagtt
     4621 ttaaagagtt ttgtatatat ttaaataacg ttttatactc tttgttacat gtttgtatca
     4681 gtatttggtg gaaaatgttt tgaggtttct ttgtgtgtgt gtgtgtgtgt gtgtgtgtgt
     4741 gtgtgattag gattctcttt tttttgtact gtttctttaa aatggagttc ttagtaacag
     4801 cggcagttcc tgaattcgaa ccaaccattt tgtatgttac aaatttgaat gagttcaata
     4861 ataacaggct atcatgcctt ttttagtgtt ttttaatttt tagaactcgc cacataaatt
     4921 gtaagtgatt gtgggtctca caacactagc aacttttaag tgtcttagca ccacacgcag
     4981 cgtgcctgct cctagcaacc gagggctcca aggacaacat cacccaggtg aggatgtggc
     5041 ctgagccacc ccagacagcg tcagccttcc aggccctacc tctgtccaca gtggacaaaa
     5101 gaggtcagga gttcagtagg gtgtccttca gtccatctgg gagagtgagg aagaagagat
     5161 tcaaaaagtg gagacagtgg agctggcgag ttttctaggt tagttcacag gctgacttac
     5221 agggcactag gaggcaggct aggaaaaggg cagcctgtgg tcagagttga aagtcataat
     5281 tagacctata gctctctatt gtcaggtttt gtcatagaac tcaccaacta ttccgaagac
     5341 atatatatac ttcaagggta tcaagtatat ctctggttct tgatagggac aaaagggcag
     5401 gtttgactta accctttgct gtctacacag ttgggttcct gttctgggtg ctactgccaa
     5461 atgttctggt acttaagtgt cgagacgccc agcctcacca ccgacttagc actgcagcag
     5521 cctgtactct gcaactggcc atagacgagc caccaggctt ctagagtcgt ctcagcaccc
     5581 tctcaaggtc acctgactgg agcactgccg acgacgtgct cttggtcaca tccctgtata
     5641 gttctctggg aaagctataa atatatatat tttggttatt gttttgtgtt ttccgttaca
     5701 ttttatatct tgtatttatc gcccgatatg ttttgtactt ttgttttcct aaaacaaaga
     5761 aatccatgtg tgtgtatata gagacttgca tgctagactg tagtcaatgt tcagttcctt
     5821 gaaaagtctt gctgctgtcg ggtgtgcacc ttacaccgcc gcgactgtat tcaacccatt
     5881 tcacatgtaa ataaatgagg aacgtctggc ccttgagctt cttcaagaga gttattggtg
     5941 ggtctctgac atcatacagt cgggggagtg actcattggg ggacaggctg cagaacactg
     6001 caggcttctt tccccctctg aagaatggct tctggttcct atcggcgacc aacttgtcgc
     6061 cactctgccg ctctctgttg acgacatggg tacaatccaa gggtgtgaga tattcctcgg
     6121 cttgaagtgt agttgctgtt gcgtgtcaca tcctcaccca cttgtgtcca ctgcactttc
     6181 acacgttcct gcatttgaac cttgcaataa gcctgcgtgg cagacacgca ggtccgtgca
     6241 gccgtacagt tgaggaggct gcgcccaggt tcagctcttc gcccggtccc tcatagctgg
     6301 taagtggctt tgcataatag aacccaaata ttttgctctc aatcttgccc tttgtggtta
     6361 tgtacatatt gacaaatatt catttattca acaaataaaa gttatgtgca aaaaaaaa
//
