LOCUS       NM_172617               2953 bp    mRNA    linear   ROD 13-JUN-2024
DEFINITION  Mus musculus zinc finger protein 523 (Zfp523), transcript variant
            1, mRNA.
ACCESSION   NM_172617 XM_001472199 XM_001478777
VERSION     NM_172617.4
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2953)
  AUTHORS   Guo,G., Huss,M., Tong,G.Q., Wang,C., Li Sun,L., Clarke,N.D. and
            Robson,P.
  TITLE     Resolution of cell fate decisions revealed by single-cell gene
            expression analysis from zygote to blastocyst
  JOURNAL   Dev Cell 18 (4), 675-685 (2010)
   PUBMED   20412781
REFERENCE   2  (bases 1 to 2953)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   3  (bases 1 to 2953)
  AUTHORS   Prigge,J.R. and Schmidt,E.E.
  TITLE     Interaction of protein inhibitor of activated STAT (PIAS) proteins
            with the TATA-binding protein, TBP
  JOURNAL   J Biol Chem 281 (18), 12260-12269 (2006)
   PUBMED   16522640
  REMARK    GeneRIF: analysis of gene regulatory interplay between TBP, PIAS1,
            PIAS3, PIASx, PIASy, ZFP523, and transcription factors
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC126937.3.
            
            On Nov 4, 2022 this sequence version replaced NM_172617.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK028222.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849384
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-349               AC126937.3         84652-85000
            350-486             AC126937.3         87032-87168
            487-642             AC126937.3         97272-97427
            643-723             AC126937.3         102441-102521
            724-801             AC126937.3         102623-102700
            802-1001            AC126937.3         105249-105448
            1002-1118           AC126937.3         107586-107702
            1119-1194           AC126937.3         107914-107989
            1195-1320           AC126937.3         108483-108608
            1321-1500           AC126937.3         108736-108915
            1501-1734           AC126937.3         109590-109823
            1735-1898           AC126937.3         109910-110073
            1899-2063           AC126937.3         110561-110725
            2064-2177           AC126937.3         111930-112043
            2178-2953           AC126937.3         112586-113361
FEATURES             Location/Qualifiers
     source          1..2953
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 14.63 cM"
     gene            1..2953
                     /gene="Zfp523"
                     /gene_synonym="2810027J07; Znf76"
                     /note="zinc finger protein 523"
                     /db_xref="GeneID:224656"
                     /db_xref="MGI:MGI:2687278"
     exon            1..349
                     /gene="Zfp523"
                     /gene_synonym="2810027J07; Znf76"
                     /inference="alignment:Splign:2.1.0"
     exon            350..486
                     /gene="Zfp523"
                     /gene_synonym="2810027J07; Znf76"
                     /inference="alignment:Splign:2.1.0"
     exon            487..642
                     /gene="Zfp523"
                     /gene_synonym="2810027J07; Znf76"
                     /inference="alignment:Splign:2.1.0"
     CDS             570..2276
                     /gene="Zfp523"
                     /gene_synonym="2810027J07; Znf76"
                     /note="isoform 1 is encoded by transcript variant 1; zinc
                     finger protein 76"
                     /codon_start=1
                     /product="zinc finger protein 76 isoform 1"
                     /protein_id="NP_766205.1"
                     /db_xref="CCDS:CCDS28573.1"
                     /db_xref="GeneID:224656"
                     /db_xref="MGI:MGI:2687278"
                     /translation="MESLGLQTVRLSDGTTAYVQQAVKGEKLLEGQVIQLEDGTTAYI
                     HQVTIQKESFSFEDGQPVQLEDGSMAYIHHTPKEGCDPSALEAVQLEDGSTAYIHHPV
                     PVPSDSAILAVQTEAGLEDLAAEDEEGFGTDTVVALEQYASKVLHDSPASHNGKGQQV
                     GDRAFRCGYKGCGRLYTTAHHLKVHERAHTGDRPYRCDFPSCGKAFATGYGLKSHVRT
                     HTGEKPYKCPEELCSKAFKTSGDLQKHVRTHTGERPFRCPFEGCGRSFTTSNIRKVHV
                     RTHTGERPYTCPEPHCGRGFTSATNYKNHVRIHTGEKPYVCTVPGCGKRFTEYSSLYK
                     HHVVHTHCKPYTCSSCGKTYRQTSTLAMHKRSAHGELEATEESEQALYEQQQLEAASA
                     AEESPPPKPTHIAYLSEVKEESSAIPTQVAMVTEEDGPPQVALITQDGTQQVSLSPED
                     LQALGSAISVVTQHGSTTLTIPGHHEELATSGTHTVTMVSADGTQTQPVTIITSGALV
                     TEDSSVASLHHQQVALLATANGTHIAVQLEDQQTLEEAISVATAAMQQGAVTLETTES
                     GC"
     exon            643..723
                     /gene="Zfp523"
                     /gene_synonym="2810027J07; Znf76"
                     /inference="alignment:Splign:2.1.0"
     exon            724..801
                     /gene="Zfp523"
                     /gene_synonym="2810027J07; Znf76"
                     /inference="alignment:Splign:2.1.0"
     exon            802..1001
                     /gene="Zfp523"
                     /gene_synonym="2810027J07; Znf76"
                     /inference="alignment:Splign:2.1.0"
     exon            1002..1118
                     /gene="Zfp523"
                     /gene_synonym="2810027J07; Znf76"
                     /inference="alignment:Splign:2.1.0"
     exon            1119..1194
                     /gene="Zfp523"
                     /gene_synonym="2810027J07; Znf76"
                     /inference="alignment:Splign:2.1.0"
     exon            1195..1320
                     /gene="Zfp523"
                     /gene_synonym="2810027J07; Znf76"
                     /inference="alignment:Splign:2.1.0"
     exon            1321..1500
                     /gene="Zfp523"
                     /gene_synonym="2810027J07; Znf76"
                     /inference="alignment:Splign:2.1.0"
     exon            1501..1734
                     /gene="Zfp523"
                     /gene_synonym="2810027J07; Znf76"
                     /inference="alignment:Splign:2.1.0"
     exon            1735..1898
                     /gene="Zfp523"
                     /gene_synonym="2810027J07; Znf76"
                     /inference="alignment:Splign:2.1.0"
     exon            1899..2063
                     /gene="Zfp523"
                     /gene_synonym="2810027J07; Znf76"
                     /inference="alignment:Splign:2.1.0"
     exon            2064..2177
                     /gene="Zfp523"
                     /gene_synonym="2810027J07; Znf76"
                     /inference="alignment:Splign:2.1.0"
     exon            2178..2953
                     /gene="Zfp523"
                     /gene_synonym="2810027J07; Znf76"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2933..2938
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp523"
                     /gene_synonym="2810027J07; Znf76"
                     /note="hexamer: AATAAA"
     polyA_site      2953
                     /gene="Zfp523"
                     /gene_synonym="2810027J07; Znf76"
                     /note="major polyA site"
ORIGIN      
        1 gcgtcacccg gcggccagcg gagagaagag cgaggcggag ctccgaggct cgcctgagga
       61 gactcggcgg cctgggctcc ggggcccggg aaccgggata agcaggccgg ccgccgcggc
      121 ggaggggggc gggctggagc gtggccccgc gctggtcatc cgggttccgg ggcccggcgg
      181 aggccgcgcc gggagcgaga gggaagtgcg gccgccctgg aacctggata tcgcgcgagg
      241 caagccgcgc gcgggcgggc tatggcgcag gcgggttgcg gggccggcgc tggtggcagg
      301 gcccggtgca tggtggtctg tcggcggagt cgccctcggg ggctgtcagg cacagaggat
      361 cttaggacct gcttcagagg agaagataag agagaccttg cttctcacgt cctcagattg
      421 ccagcgtttc tgaaccaagt taaccctatc ggctgtcctg ctaatccagc gctgtaccac
      481 taaacgattg gtgacccaga aggaaatctg tgacctcagt ggtgaccaga agccaacttc
      541 atgtctgaag gcacaagtgg cagtttgtca tggaaagcct ggggctgcaa acggtgaggc
      601 tcagtgatgg gacaacagcc tacgtccagc aggctgtcaa aggggagaag ctgcttgaag
      661 ggcaagtgat ccagctggag gacgggacca ctgcgtacat tcaccaggtg acgatacaga
      721 aagagtcttt ctcctttgaa gatggtcagc ccgtgcagct ggaagacggc agcatggcct
      781 acatacacca cacacccaaa gagggctgtg accccagcgc cctggaagct gtccagctgg
      841 aagacggttc cactgcctac atccatcacc ctgtgcctgt gccgtcggac agcgccatcc
      901 tggctgtgca gacggaggcg ggcttggagg acctggcagc ggaagacgag gaaggcttcg
      961 gcacggacac agtggtggcc ctggagcagt atgccagcaa ggttctgcac gatagccctg
     1021 cttcccacaa tggcaaaggg cagcaggttg gagaccgagc tttccgctgt ggctacaagg
     1081 gctgtggtcg tctctacacc actgcccatc acttaaaggt ccacgaacga gctcacacag
     1141 gggaccgccc atacaggtgt gactttccca gctgtggaaa ggcctttgca acaggctatg
     1201 ggctaaaaag tcatgttcgt actcacacgg gtgagaaacc atacaagtgc ccagaggagc
     1261 tgtgcagcaa agccttcaag acctcagggg acctgcagaa acacgtgcgg acccacacag
     1321 gtgagcgccc attccggtgc ccttttgagg gctgtggccg ctccttcacc acatcaaata
     1381 tccgcaaggt acatgtgcgc acccacacag gcgagcggcc ctacacctgc cccgagcccc
     1441 actgtggtcg tggcttcacc agcgccacca actacaagaa tcatgtgcgc atccatacag
     1501 gggagaagcc atacgtttgc acggtgccag gctgcggaaa gcgctttacg gagtactcga
     1561 gcctgtacaa acaccacgtg gtgcacacac attgcaagcc ctacacgtgc agtagctgtg
     1621 gcaagaccta ccggcaaacc tccaccctgg ccatgcacaa gcgcagcgca cacggggagc
     1681 tggaggccac ggaggagagc gagcaggccc tgtatgagca gcagcagctg gaggccgcct
     1741 ctgctgctga ggaaagcccc ccacccaaac caacccacat tgcttacctt tcggaagtga
     1801 aggaagagag cagtgccatc ccaacccaag tagccatggt gacggaggag gatgggcccc
     1861 ctcaggtggc tctgatcact caggacggta cccagcaggt cagcctgtcc ccagaagacc
     1921 tgcaggccct ggggagtgcc atcagtgtgg tgacacagca cggcagcacc accctcacca
     1981 tccccggtca tcatgaagaa ctagccacat ctggcacaca cacggtcacc atggtcagcg
     2041 ctgatggcac gcagactcag cccgtcacaa tcattacctc tggggccttg gtgactgagg
     2101 actcaagcgt ggcgtctctt catcaccaac aggtggcgct gttggccaca gccaacggaa
     2161 cacacatcgc agtgcagctg gaggaccagc agaccctgga ggaggccata agcgtagcca
     2221 ctgctgctat gcagcaaggg gctgtgaccc tggaaaccac agagagcggc tgctgagccc
     2281 aagaggacca gctcccacac cacactggag aaggctccat gctcacaggc agccctgcct
     2341 ccggggcccc cagccacagc tgaccccaag aagatggccg cataggcctc aggggtgatg
     2401 aggcaacagg aaaatggcct ctagtggaaa ggtctgtggg ctacacccaa gatgagggcc
     2461 aggcagcagg cagtcgacac tgagcttggt caccaggctg ccagacacct gcgtccctcc
     2521 cttggcagga tattattcct gctctgtcca ctcccttcct cagggaggtg gtgactaggt
     2581 ggacgaggac tggcctccac cctggctgct agtaccacca ggggaaaggc cgacagcttt
     2641 cagcccagcg cctcccagca ataaccgtct cctggggcta cggtggccaa gatgcctagc
     2701 cacttggcac cagggacttc ccaccaccac agtcagaatt aattcctcag gggcctgtgg
     2761 ctggagtgaa ggtgcctctt cgcttgtctg tggcagagag gcaagcgagt ggcctgtacc
     2821 cagactgctg gggactgggt ttcatttgtt ttgtggtttg ggtttttaat cctattttga
     2881 taattttttt tcctgctctg ggtggtggtg gcaaacgggc ggatgagtat ttaataaaag
     2941 ttgcaagttt cca
//
