LOCUS       NM_001081144            6832 bp    mRNA    linear   ROD 07-AUG-2024
DEFINITION  Mus musculus zinc finger protein 518B (Zfp518b), transcript variant
            1, mRNA.
ACCESSION   NM_001081144 XM_144310
VERSION     NM_001081144.3
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6832)
  AUTHORS   Maier,V.K., Feeney,C.M., Taylor,J.E., Creech,A.L., Qiao,J.W.,
            Szanto,A., Das,P.P., Chevrier,N., Cifuentes-Rojas,C., Orkin,S.H.,
            Carr,S.A., Jaffe,J.D., Mertins,P. and Lee,J.T.
  TITLE     Functional Proteomic Analysis of Repressive Histone
            Methyltransferase Complexes Reveals ZNF518B as a G9A Regulator
  JOURNAL   Mol Cell Proteomics 14 (6), 1435-1446 (2015)
   PUBMED   25680957
  REMARK    GeneRIF: Functional Proteomic Analysis of Repressive Histone
            Methyltransferase Complexes Reveals ZNF518B as a G9A Regulator
REFERENCE   2  (bases 1 to 6832)
  AUTHORS   Okazaki,N., F-Kikuno,R., Ohara,R., Inamoto,S., Koseki,H.,
            Hiraoka,S., Saga,Y., Seino,S., Nishimura,M., Kaisho,T., Hoshino,K.,
            Kitamura,H., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: IV. The complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (3), 205-218 (2004)
   PUBMED   15368895
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC093570.30.
            
            On Jun 8, 2022 this sequence version replaced NM_001081144.2.
            
            Transcript Variant: This variant (1) represents the longest
            transcript. Variants 1-5 all encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14777535.1255726.1,
                                           SRR12282455.28119060.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164138 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-99                AC093570.30        124267-124365       c
            100-165             AC093570.30        122781-122846       c
            166-463             AC093570.30        122073-122370       c
            464-6832            AC093570.30        108073-114441       c
FEATURES             Location/Qualifiers
     source          1..6832
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 20.77 cM"
     gene            1..6832
                     /gene="Zfp518b"
                     /gene_synonym="6820424L24Rik; Znf518b"
                     /note="zinc finger protein 518B"
                     /db_xref="GeneID:100515"
                     /db_xref="MGI:MGI:2140750"
     exon            1..99
                     /gene="Zfp518b"
                     /gene_synonym="6820424L24Rik; Znf518b"
                     /inference="alignment:Splign:2.1.0"
     exon            100..165
                     /gene="Zfp518b"
                     /gene_synonym="6820424L24Rik; Znf518b"
                     /inference="alignment:Splign:2.1.0"
     exon            166..463
                     /gene="Zfp518b"
                     /gene_synonym="6820424L24Rik; Znf518b"
                     /inference="alignment:Splign:2.1.0"
     exon            464..6832
                     /gene="Zfp518b"
                     /gene_synonym="6820424L24Rik; Znf518b"
                     /inference="alignment:Splign:2.1.0"
     CDS             657..3905
                     /gene="Zfp518b"
                     /gene_synonym="6820424L24Rik; Znf518b"
                     /codon_start=1
                     /product="zinc finger protein 518B"
                     /protein_id="NP_001074613.2"
                     /db_xref="CCDS:CCDS39078.2"
                     /db_xref="GeneID:100515"
                     /db_xref="MGI:MGI:2140750"
                     /translation="MQIREMKDIGEQLYTTQVNGGPSSLTMSPKQPNRATRTERQEAQ
                     TLLYQGSEAEAATMTIATCVQCKSVHKIPTQDLRKGPGQSQDTYVCFKCSLRAVPTQL
                     HFVNNNAGAAHVRNETETISSPVNKFKVRNFKPGKYYCDKCRFSTKDPLQYRKHTLQH
                     EEIRFICSHCSYISYTKGEFQRHLVKHTGIFPYRCEYCDYGAIRNDYIVKHRRRVHER
                     AGAKRPFKTVAKLEPKRTSIPKQSMELSKGPSPRAAFQNKLSDQLSRFSLHANKDKTH
                     NLMLLPELKKYQKDVVCIPNKVTLSEPREVSLLGNKNVEVEVLSPSKEPVHPGMPLTV
                     MAPSELVVPTNCLAQLMDVKVVNGAQQLVLKLFPLEENARLETSRGDGGTSECLSTEK
                     GSGGQKKMLSPEASRSLAVEGNAGDFVGLDRLHSLVQKQLKNVKWVKSCNFFMPNSGV
                     HSQQESFLGSDTIKELQKSHSLCPPRALPSAAIKSHSPASVQNSVPYGPGATVSHFLS
                     KAAVAFADDRRGARSNSQQLLPLASLPSKVPFSGEKGLLPIGESDLEARNRISRPETL
                     VSSDRKLEDKQMESKAVGNTGQVSSVQNKEYLHINITGEDKPRSQQPGDQPGQPKTSE
                     TAGATFEGPIISSVFSLSSGSENVPEAIKWNSSTTKIKSIELLRRKIAQLIESCGKPS
                     SLSANSAQRRSIGQAPKLTSKATPKAIQEMSVSLTGPGPTPGPSVGPLQKPPNEDSIT
                     GSRQLVPQQVCPQFISANDGKMENRVTRKTPVATPVLIPKGAVLRVLNSSEDAHIIEA
                     TCDTPVSIPCSEAQLAGTLPFCPMKQTGSGSQPLTCRSGPADMSPGLETSLRPKSRKE
                     DTICSATAKKMVPVYSTAPGSSDSIRQGRPVSRNLTVSKNKTKQVNSTKKKNKMQANP
                     GRYFKDPPSFFQVARQLRLIAAKPDQLIKCPRRNQPVIVLNHPDVDSPEVTNVMKVIN
                     KYKGNVLKVVLSERTRCQLGVRRYHMRLTYQNVAETNHMKRQMMLKMKLKKVHKNNYQ
                     VVGSMPDDPAQCVFKCWFCGRLYEDQEEWMSHGQRHLIEATRDWDVLSSKGK"
     regulatory      6811..6816
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp518b"
                     /gene_synonym="6820424L24Rik; Znf518b"
                     /note="hexamer: AATAAA"
     polyA_site      6832
                     /gene="Zfp518b"
                     /gene_synonym="6820424L24Rik; Znf518b"
                     /note="major polyA site"
ORIGIN      
        1 acagcgggcg cggcggcggc ggtctgcggg cggtagccgg cggtctagac gcctgtccgt
       61 ccgctgggat ctgggaccgt gcggtgccgc ggcgtccggg cactcctgga tcctctgagt
      121 caatgcaatg gccggccttt catgaccaag tctgctgaca ctgtggcccg ttggcgcagc
      181 cctggcttcc aagcatagat gtctacacca cgggcctgaa gtcctgagac ttgtcctcgg
      241 tggctaacaa ggcctgaaag aaaaggaaga gccatagaga cttgccacac tcttgacttc
      301 tgggcctgga aaagcagtgc ccaagaggcc aggaatcctg gctgtaacct ctgctcacaa
      361 gacgggagtg ttagctggat gctgcctgcc accactttcc acctcagtgt gacctagaaa
      421 aagccacata ccatctcctg gcccttcgtt ttaaaagaag cagtgttgcc tggaaacaga
      481 attgaaagca ttcgtattgt ggctcacatc ttcttgtaaa aggacataaa acgtgattga
      541 ttattaaata tttaccacga agtgcctgct gctccaccag tcactggatg tgggaggatg
      601 cctgcagaag gtttcattga ttgacatctt tctgattttc aggtggctat gtgcatatgc
      661 agataaggga gatgaaggat attggagaac aactctatac cacacaagtg aatgggggac
      721 ccagttcctt gaccatgtcc cccaaacaac ctaatagagc aactcggacg gagagacagg
      781 aagctcagac cctattgtac caaggttcag aggcagaggc tgccaccatg accattgcta
      841 cttgtgtaca gtgcaaaagt gttcacaaga tccccactca agacttgagg aaaggccctg
      901 ggcagagcca agacacttat gtctgcttta agtgcagcct tcgagcagtg cctacccagc
      961 tgcattttgt gaacaacaac gctggtgctg cgcatgtcag aaatgaaacg gaaaccatct
     1021 cgagccctgt aaataaattt aaggttagga acttcaagcc aggcaaatac tactgtgata
     1081 agtgtcgctt ctctacaaag gacccactgc agtaccgaaa gcacacgctg cagcacgagg
     1141 agatcaggtt catctgttcc cactgcagct acatctccta cacgaaaggg gagttccaga
     1201 gacatctggt gaagcacacg ggcatcttcc cttatcgctg tgagtactgc gactatggtg
     1261 ctattcgcaa tgactacatc gtcaagcaca ggaggagggt ccacgagcgg gctggggcca
     1321 agcggccatt caaaactgtg gccaagctgg aacccaagag aaccagcatc ccaaagcaga
     1381 gcatggaact ctcaaagggc cccagtccca gggctgcctt ccaaaacaag ttgtcggacc
     1441 agctgtctcg gttctctctc cacgcgaaca aagacaagac acacaacctg atgttattac
     1501 ccgagctaaa gaagtaccaa aaagatgtag tgtgtattcc caacaaagtg accctgtccg
     1561 agcccaggga ggtgagcctg ttggggaaca agaatgttga ggtggaagtg ctgtccccct
     1621 caaaggaacc cgtgcatcca gggatgccgc tgaccgttat ggcgccctca gagctggtgg
     1681 tccccaccaa ctgtctggcc cagttgatgg acgtgaaggt tgtcaatggt gctcagcagc
     1741 ttgtgcttaa actgtttccg ttggaagaaa acgcccgcct ggaaacgagc cgaggagatg
     1801 gaggcacttc cgagtgtctg agtaccgaga agggctcagg gggacagaaa aaaatgcttt
     1861 ctccagaagc atcgaggtca ctagccgtgg aagggaatgc cggagacttt gtgggcctgg
     1921 atcgtctgca ctctttggtt cagaaacagc ttaaaaatgt gaagtgggtg aagtcttgca
     1981 attttttcat gccgaattct ggtgtccaca gtcaacaaga atctttcctc ggttccgata
     2041 caatcaagga gttacagaaa tctcacagtc tgtgtccgcc tcgagccctt ccttctgctg
     2101 ccataaaaag tcattctcca gcctctgtac aaaatagtgt tccctatggt cctggggcca
     2161 cagtgagcca tttcttgagt aaagcagctg ttgcttttgc tgatgacaga agaggggccc
     2221 gcagtaactc ccagcagctc ctgccgcttg cctctttgcc ttcaaaggtt cccttctctg
     2281 gagagaaggg cttattgcct ataggtgaaa gtgacttaga agcgaggaat aggattagtc
     2341 gtcctgaaac cttggtttcc tctgatagga agctggaaga caagcagatg gaaagcaagg
     2401 cagtgggaaa tacgggccag gtttcctctg tgcagaataa agagtattta cacataaaca
     2461 taactggaga agataaaccg aggtcccaac agcctgggga tcagcctggg cagcccaaga
     2521 cttctgaaac agcaggtgcc acgtttgaag gcccaatcat ctcatccgtg ttttcgctga
     2581 gctctggatc tgaaaatgta ccggaggcca ttaaatggaa tagctcaacc accaaaataa
     2641 agtccattga actgctgcgc agaaagatag ctcagttgat tgaatcttgt ggcaagcctt
     2701 cctctttgtc tgccaatagt gctcagcgac gttccatagg tcaggcacca aagctgacct
     2761 caaaagcaac tcccaaggct attcaagaaa tgagtgtgtc ccttactggc cctggcccta
     2821 cccctggccc ttctgtgggt cctctccaaa aacctccaaa cgaggacagt attactggca
     2881 gcagacagct tgttccacag caggtctgtc cccagtttat cagtgctaat gatgggaaaa
     2941 tggaaaacag agtgaccaga aagactcctg ttgctactcc agtgctgatc cccaaagggg
     3001 ccgtgttgag ggtccttaac tcttctgaag atgctcacat catagaggct acctgtgaca
     3061 cacctgttag cataccttgc agcgaagccc agttagcagg aacacttcca ttctgcccta
     3121 tgaaacagac aggctcgggc tcccagccct tgacatgcag aagtggaccg gcagacatgt
     3181 ctcccggtct ggagacatct cttcggccca aatctagaaa agaggacaca atctgcagtg
     3241 ccactgctaa gaaaatggtc cctgtgtaca gcacggcacc aggaagcagt gactccatca
     3301 ggcaaggaag gccagtttct agaaacctaa ctgtaagcaa gaataaaacc aagcaagtga
     3361 actcaaccaa gaagaagaac aagatgcagg ccaatcccgg ccgttatttc aaagaccccc
     3421 cctccttttt tcaggtggca aggcagctgc gcctcatagc tgccaaacca gatcagttga
     3481 ttaaatgtcc ccgtcggaac cagcctgtca ttgtgctaaa tcatcctgac gttgactccc
     3541 ccgaagtgac caatgtgatg aaggtaatca acaagtacaa aggcaatgtc ctcaaggttg
     3601 tcctgtctga gaggactagg tgtcagctgg gtgtccggcg gtaccatatg cggctgacct
     3661 accagaatgt ggcagaaact aaccacatga agaggcagat gatgttgaaa atgaaactga
     3721 agaaggttca taaaaacaac tatcaggtgg tgggctcgat gccggacgac cccgcccagt
     3781 gtgtctttaa gtgctggttc tgtgggaggc tctacgaaga ccaggaagag tggatgagtc
     3841 acggccagag gcatttgata gaggccacca gagactggga tgtcctctct tcaaagggca
     3901 aatgagtgaa acttggtctt tgaaattcga ttttcttcta gttttcatgg cttagggtgg
     3961 caccctagac ttttgatgca gtagaagaaa gggggttgct tattccttag agtcaccata
     4021 ggaagggtga gagccctgtc cttacctgag ctctgtggct ggaccaggga aaggtgggag
     4081 cccctgaaat tctactggtt ttgattgaaa ggatgtaatg ttctccacag gttttcagtg
     4141 ggatctgagg ccttccttgc ttagttctta tttttctgag tagacacatc tttcatagtc
     4201 cacttagagg ggtgggttta cgattgacac actttgtgga taaatgctgc tgaagggtgt
     4261 gtcttggggc acacatccac tttgattttg ctttactctt ccagaatagt tgctgcgtaa
     4321 tagaaattac atttttctac ttgatgggtc atcttaaatc tggttagaga gctgtacttg
     4381 gcccctccca ctgtgagttc tagctgtgct ctgcggagcc gtgagctttg ctttaattgg
     4441 gcgtgtatca gcaacagttt ttaggagaag aaaagacaga tttccagtat ttagcttttg
     4501 cttgctttta aaatataatt ggttgataat agttgggtag gggatacata attggttttt
     4561 tggttttgtt ttggataaag aaggaaaaaa tatatatata aaatcaagtc tgtcctttgc
     4621 atctaatact ccaccaaaca taaatggcca ttttaaattg tgaaggagca gattcattaa
     4681 aaaacagatt ggcctcaatg gtgccattcc aggtagactt gaaagcaggc tgtgtagggt
     4741 ctgctgtgac tggttcttca cctggggact cagtgcaaag cctgagagtg tgccagcaca
     4801 cacttgagca taggatcata gggctgctcc ccgggccaga tctgttctcc ttttgcctgt
     4861 tcctgagcag gccttcctgg ggaagagcct agtctccgtg cacatttttc ctcatgaaca
     4921 ctagcaactg caggagtcaa caacatggaa agaaaaccac aattgtctgt gggggcttta
     4981 agaacactac ccctgttttc agtgatagga acaggctact cctagctcag ccacagatgt
     5041 tcctctcttg cttacatttt ctaataggac tgcccctcca ccaagaggtg ttaagactca
     5101 gcgatctaca aggcaccttt gcacattagg agaaagttta tctcctacat gggtagggct
     5161 tcctgggcaa gagcagctca ggcaaagggc actaaccagt gaccagccag tgaccttgag
     5221 agtgtacata catccttggg gggacttagt gatggatgct gtgaggggag cagggggagg
     5281 ggtggttaga tctgaaaatg gtaccagtga cttcttatct ctgggtgact tccggacttt
     5341 gccttttcac gtggcaagtc ttagttcatc ctctcacagt tgggatactc cttttaagct
     5401 cgttttcatt atacatactt ggcttttctt gggtacagtt cagtacctga tcgttttgtt
     5461 aattgataat tttaatttaa aagttgcatt tttatatatg tgtatatatg tgtacacata
     5521 taaatatttt ttaccatatg caaattgcaa cagctaattt tctgatttcc tattttataa
     5581 tgatacatga gctggggaaa tataaagctt tttatattct agaaataatt tattttgaaa
     5641 gaacattttt acaatggttt catctcattt ttagaaaatg aaagcacagt aactgatggg
     5701 acctgattcc catgagcaac ctggagtagc cagcccctgt gggtcactgt attgcagcat
     5761 ttcgtcctgc ctgctgctct gtggccatgt gatgccaagc agtctcaagt ctgatctgtg
     5821 gtgcagcctg gtaaccaacc ctcccgctca aacttgaatc tcacgtggca ggaggggcta
     5881 tgggatccgc tcgtcttcct cactgccgca cagctcccca ccccacccca cccgactcga
     5941 ccaagagctg ccacagatca gcatcaacag aatccttaca ctctgctgca acagctgctg
     6001 ttttcaagta ttatctaaaa tagctaggac ttgtatggag ctggggttag tgagcagaat
     6061 aggtagcgag ttttgggggg attttcataa ctacagtcct tgttgaggaa ctcggagggc
     6121 tcctggaagc ccttagcatg ggaaatgaga acgtgactgg cttctccaac agagttttag
     6181 acataagttt atcatgtagg taagagtggg gaaggactcc atttctgatg ggttggaagg
     6241 aggacagaaa tgggatactt ccttccatag ccttaccttg acattgaagg atctctagtc
     6301 attaaatttt gttgatagta cttataaaat tattttaaac ttatttttta atctagattt
     6361 tcttactttg ggggaccaga aatgaaagga tcttcttata tttatgatat aggcaagtag
     6421 agttaaaaaa aaaactgaag cctctgtcgc ttaagtgtcc tctcagtaga ttatatttta
     6481 ttcaaaattt tatctctagc ccaaaacatt ttgtgagccc ccatcatagg tcacacatag
     6541 ttgacataaa ctaaacacga tgtatcgacc ctccaaagtt tcatccccca ttctttagaa
     6601 tttacataag ccacccggaa gatgaaggta cggtgttgct cagccttcag aaggactttt
     6661 gaatctgtga atgtctttat gagcagaaaa caaaactttg tcttaccatg tcaagcatta
     6721 cagctcccgt gtgaacagtt tgtgtgtctg tcgctctggt tcggaaacat gtttgtatat
     6781 agatagaaaa gttggcatcc gttttgttta aataaagcaa cttttaagat ct
//
