LOCUS       NM_145459               4251 bp    mRNA    linear   ROD 24-DEC-2024
DEFINITION  Mus musculus zinc finger protein 503 (Zfp503), mRNA.
ACCESSION   NM_145459
VERSION     NM_145459.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4251)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4251)
  AUTHORS   Chen,S.Y. and Liu,F.C.
  TITLE     The Fgf9-Nolz1-Wnt2 axis regulates morphogenesis of the lung
  JOURNAL   Development 150 (16) (2023)
   PUBMED   37497597
REFERENCE   3  (bases 1 to 4251)
  AUTHORS   Boobalan,E., Thompson,A.H., Alur,R.P., McGaughey,D.M., Dong,L.,
            Shih,G., Vieta-Ferrer,E.R., Onojafe,I.F., Kalaskar,V.K., Arno,G.,
            Lotery,A.J., Guan,B., Bender,C., Memon,O., Brinster,L.,
            Soleilhavoup,C., Panman,L., Badea,T.C., Minella,A., Lopez,A.J.,
            Thomasy,S.M., Moshiri,A., Blain,D., Hufnagel,R.B., Cogliati,T.,
            Bharti,K. and Brooks,B.P.
  TITLE     Zfp503/Nlz2 Is Required for RPE Differentiation and Optic Fissure
            Closure
  JOURNAL   Invest Ophthalmol Vis Sci 63 (12), 5 (2022)
   PUBMED   36326727
  REMARK    GeneRIF: Zfp503/Nlz2 Is Required for RPE Differentiation and Optic
            Fissure Closure.
REFERENCE   4  (bases 1 to 4251)
  AUTHORS   Shang,Z., Yang,L., Wang,Z., Tian,Y., Gao,Y., Su,Z., Guo,R., Li,W.,
            Liu,G., Li,X., Yang,Z., Li,Z. and Zhang,Z.
  TITLE     The transcription factor Zfp503 promotes the D1 MSN identity and
            represses the D2 MSN identity
  JOURNAL   Front Cell Dev Biol 10, 948331 (2022)
   PUBMED   36081908
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 4251)
  AUTHORS   Lee,D.R., Rhodes,C., Mitra,A., Zhang,Y., Maric,D., Dale,R.K. and
            Petros,T.J.
  TITLE     Transcriptional heterogeneity of ventricular zone cells in the
            ganglionic eminences of the mouse forebrain
  JOURNAL   Elife 11, e71864 (2022)
   PUBMED   35175194
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 4251)
  AUTHORS   Arlotta,P., Molyneaux,B.J., Jabaudon,D., Yoshida,Y. and
            Macklis,J.D.
  TITLE     Ctip2 controls the differentiation of medium spiny neurons and the
            establishment of the cellular architecture of the striatum
  JOURNAL   J Neurosci 28 (3), 622-632 (2008)
   PUBMED   18199763
REFERENCE   7  (bases 1 to 4251)
  AUTHORS   Sajan,S.A., Warchol,M.E. and Lovett,M.
  TITLE     Toward a systems biology of mouse inner ear organogenesis: gene
            expression pathways, patterns and network analysis
  JOURNAL   Genetics 177 (1), 631-653 (2007)
   PUBMED   17660535
REFERENCE   8  (bases 1 to 4251)
  AUTHORS   McGlinn,E., van Bueren,K.L., Fiorenza,S., Mo,R., Poh,A.M.,
            Forrest,A., Soares,M.B., Bonaldo Mde,F., Grimmond,S., Hui,C.C.,
            Wainwright,B. and Wicking,C.
  TITLE     Pax9 and Jagged1 act downstream of Gli3 in vertebrate limb
            development
  JOURNAL   Mech Dev 122 (11), 1218-1233 (2005)
   PUBMED   16169709
REFERENCE   9  (bases 1 to 4251)
  AUTHORS   Watanabe,K., Kamiya,D., Nishiyama,A., Katayama,T., Nozaki,S.,
            Kawasaki,H., Watanabe,Y., Mizuseki,K. and Sasai,Y.
  TITLE     Directed differentiation of telencephalic precursors from embryonic
            stem cells
  JOURNAL   Nat Neurosci 8 (3), 288-296 (2005)
   PUBMED   15696161
REFERENCE   10 (bases 1 to 4251)
  AUTHORS   Chang,C.W., Tsai,C.W., Wang,H.F., Tsai,H.C., Chen,H.Y., Tsai,T.F.,
            Takahashi,H., Li,H.Y., Fann,M.J., Yang,C.W., Hayashizaki,Y.,
            Saito,T. and Liu,F.C.
  TITLE     Identification of a developmentally regulated striatum-enriched
            zinc-finger gene, Nolz-1, in the mammalian brain
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2613-2618 (2004)
   PUBMED   14983057
  REMARK    GeneRIF: Nolz-1 mRNA was dramatically induced on neural induction
            of P19 embryonal carcinoma cells by retinoic acid, suggesting that
            Nolz-1 activation may be involved in neural differentiation
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC066027.1.
            
            On Feb 22, 2004 this sequence version replaced NM_145459.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC066027.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164137, SAMN01164142
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..4251
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 12.0 cM"
     gene            1..4251
                     /gene="Zfp503"
                     /gene_synonym="B830002A16Rik; Nolz-1; Nolz1; Znf503; Zpo2"
                     /note="zinc finger protein 503"
                     /db_xref="GeneID:218820"
                     /db_xref="MGI:MGI:1353644"
     exon            1..577
                     /gene="Zfp503"
                     /gene_synonym="B830002A16Rik; Nolz-1; Nolz1; Znf503; Zpo2"
                     /inference="alignment:Splign:2.1.0"
     exon            578..1658
                     /gene="Zfp503"
                     /gene_synonym="B830002A16Rik; Nolz-1; Nolz1; Znf503; Zpo2"
                     /inference="alignment:Splign:2.1.0"
     CDS             1329..3287
                     /gene="Zfp503"
                     /gene_synonym="B830002A16Rik; Nolz-1; Nolz1; Znf503; Zpo2"
                     /note="zinc-finger protein NOLZ1; zinc finger protein
                     Nolz-1"
                     /codon_start=1
                     /product="zinc finger protein 503"
                     /protein_id="NP_663434.2"
                     /db_xref="CCDS:CCDS36822.1"
                     /db_xref="GeneID:218820"
                     /db_xref="MGI:MGI:1353644"
                     /translation="MSTAPSLSALRSSKHSGGGGGGGGGGGSGGGSADPAWTSALSGN
                     CSGHGPGSSPAGSTKPFVHAVPPSDPLRQANRLPIKVLKMLTARTGHILHPEYLQPLP
                     STPVSPIELDAKKSPLALLAQTCSQIGKPDPSPSSKLSSVASNGGGAGGAGNGAGGDK
                     DAKSGPLKLSDIGVEDKSSFKPYSKPGSDKKEPGGGGGGGGGGGGGGGVAAEKSGFRV
                     PSATCQPFTPRTGSPSSSASACSPGGMLPSAGGGPEGKDDKKDPEAGGGGSSKGSGGA
                     SADGVPAGLGHGRISCGGGINVDVNQHSEGGPGGKALGSDCGGSSSSSSGSGPSAPTS
                     SSVLGSGLVAPVSPYKPGQTVFPLPPAGMTYPGSLAGAYAGYPPQFLPHGVALDPTKP
                     GSLVGAQLAAAAAGSLGCSKPAGSSPLAGASPPSVMTASLCRDPYCLSYHCASHLAGA
                     AAASASCAHDPAAAAAALKSGYPLVYPTHPLHGVHSSLTAAAAAGATPPSLAGHPLYP
                     YGFMLPNDPLPHICNWVSANGPCDKRFATSEELLSHLRTHTAFPGTDKLLSGYPSSSS
                     LASAAAAAMACHMHIPTSGAPGSPGTLALRSPHHALGLSSRYHPYSKSPLPTPGAPVP
                     VPAATGPYYSPYALYGQRLTTASALGYQ"
     exon            1659..4213
                     /gene="Zfp503"
                     /gene_synonym="B830002A16Rik; Nolz-1; Nolz1; Znf503; Zpo2"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      3883
                     /gene="Zfp503"
                     /gene_synonym="B830002A16Rik; Nolz-1; Nolz1; Znf503; Zpo2"
                     /note="major polyA site"
     regulatory      4007..4012
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp503"
                     /gene_synonym="B830002A16Rik; Nolz-1; Nolz1; Znf503; Zpo2"
                     /note="hexamer: AACAAA"
     polyA_site      4041
                     /gene="Zfp503"
                     /gene_synonym="B830002A16Rik; Nolz-1; Nolz1; Znf503; Zpo2"
     regulatory      4169..4174
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp503"
                     /gene_synonym="B830002A16Rik; Nolz-1; Nolz1; Znf503; Zpo2"
                     /note="hexamer: ATTAAA"
     polyA_site      4213
                     /gene="Zfp503"
                     /gene_synonym="B830002A16Rik; Nolz-1; Nolz1; Znf503; Zpo2"
                     /note="major polyA site"
ORIGIN      
        1 cgcaaatcga ggggaacgcc gaagtcccgc tccgcttccc tggaagaacc ggtttccaca
       61 ggcagccgcc cctccctctc gcgttccttc cctctcctct ccccgcatag gtcagtcctg
      121 tctggatggt ctacatcatg ccgtccagca gcccgattaa gtcccggctc ccaggactgt
      181 cgggatggcc agcggagggt agtggcgaag gacccgggag aggaggagag cgagcctgag
      241 acctgtttgc ctatgcacat ggtcaggcct cttctcttga gctattcaac tctcgctacg
      301 aacacgggtc acagaattaa ggaggtttat tctacaagta acctccagaa ctcgggctat
      361 atttgatggc atggctcttt ggaaagaaat tcccgagtct ggggtgggaa cactaccgag
      421 gtcgacaact ggacatcctc aagttacatt cccgggaggg attatgccag agaggcggga
      481 aacctccgcg ttagacgtcg cctccagcgt cgttcttagg tactcagcag acccgaactg
      541 ggcgacccgg attgaccgaa gcacccaaag gtagaaggct cccactcatc cctggagttg
      601 actgttcagc aggtatccac attaccgcct gcgtttcttc tcccgaagtc tgttaacact
      661 ccctccctcc aaaggtttca gtttgttttc ctgctgggaa aacgaagaac gacgaagaga
      721 aaaaagaagg aaggcggtag atgacaaacg tagaataaat gtccatctcg tccgggtagc
      781 gaaatcgagg gaggggacaa gccgaggggc ggcgaagagg gagctgccca ttaaaaccag
      841 ctctgagatt cctggcggtg gcggcggcgc gggacgcgtc acatcccctt gaccctccaa
      901 tcacctcggg ctcccatttg attggaaggc ggcaaaggct ttaatctccc cctcggtgca
      961 gctgcttttg aagtgagttt cctcgccaga gcccgggctg gacaagcagc gacacacatc
     1021 gcagagcgca gcgccggctc ggggccggga gagcgcagcg cagggcgcag cccgaggcag
     1081 acaccgcgca ccgcggggac actcccgcag tctgtcctgc tcttctagcc ccatcacggc
     1141 tccgctgcgg gccacccagg attattcgct tctggctccc ggcggcgaga aagcgcgcgg
     1201 ggctcccgcg tccgccgcgc cagctcctcc tccagctgct cccgctcccc gggcgagcgc
     1261 gcagccccga gcccgccccg cgcatctcgg agccctcccc ccgctgctcc catgcgcgcg
     1321 ggtgggtcat gagcacagcg ccctcgcttt ctgccctaag aagcagtaag cacagcggcg
     1381 gcggcggcgg cggcggcggc ggcggcggca gcggcggcgg cagcgcggac cctgcctgga
     1441 ccagcgcgct ttctggaaat tgctccggcc acggcccagg ctcctccccg gccggcagca
     1501 ccaagccttt tgtgcacgct gtgcccccct ctgaccccct gcgccaggct aaccgcctgc
     1561 ccatcaaggt gctgaagatg ctgacggcac ggactggcca cattttgcac ccagagtatt
     1621 tgcaacccct gccttccacg cccgtcagcc ccatcgagct ggacgccaag aagagcccac
     1681 tggcgctgct ggctcaaaca tgttcgcaga tagggaagcc ggacccttcg ccttcttcca
     1741 aactctcctc ggtcgcctcc aacggcggcg gcgcgggtgg tgcaggcaac ggagctgggg
     1801 gcgacaagga cgccaagtcg ggccccttga agctgagcga catcggcgtg gaggacaagt
     1861 cgagtttcaa gccttactcc aaacccggtt cagataagaa ggagccggga ggcggcggcg
     1921 gaggcggcgg cggcgggggc ggcggcgggg gtgttgctgc agagaagtca ggattccggg
     1981 taccgagcgc cacctgccag ccatttacgc ccaggacagg cagtcccagc tccagcgcct
     2041 cggcctgttc gccgggaggc atgctgccct ccgccggggg tggcccggag ggcaaggacg
     2101 acaagaaaga tccggaagct ggcggcggtg gcagcagcaa aggctccggg ggcgcctcgg
     2161 cagacggggt acccgccggg ctggggcacg gccggattag ctgcggcggc ggaattaacg
     2221 tggacgtgaa ccagcactcg gaagggggtc caggaggcaa ggctctaggc tcggactgtg
     2281 gcggctcttc cagctcaagc tcgggttcgg gccccagcgc gcccacctcg tcgtcggttt
     2341 tgggctccgg tctggtggcc ccggtatctc cctacaaacc gggccagaca gtgttccctc
     2401 taccccctgc gggcatgacc tacccaggca gcctggctgg ggcctacgct ggctacccgc
     2461 cccagttctt gccacacggt gtggcactcg accccactaa acctggcagc ctggtagggg
     2521 ctcagctggc agcggccgca gccggctctc ttggctgcag taagccagcg ggttcgagtc
     2581 ctctggccgg ggcgtcgcct ccatcagtga tgacagctag tttgtgccgg gacccatact
     2641 gcctcagcta ccactgcgcc agccacttgg ccggggctgc agccgccagc gcctcgtgcg
     2701 ctcatgatcc ggccgctgca gcagcagcgc tcaaatcggg atacccgcta gtatacccca
     2761 cgcacccact gcacggcgtt cactcctcgc tgacggctgc ggccgctgcg ggcgccacac
     2821 caccctccct agccggccac cccctctacc cctacggttt catgctccct aacgacccgc
     2881 tcccccacat ctgcaactgg gtgtctgcta atgggccgtg cgacaagcgc ttcgccactt
     2941 ccgaagagct gctgagccac ttgcggaccc atacggcctt cccagggaca gacaaactgc
     3001 tgtcgggcta ccccagttct tcgtctctcg ccagcgccgc agcagcagcc atggcttgtc
     3061 acatgcacat ccccacgtcg ggcgcaccgg gcagcccagg gactctggcg ctgcgcagcc
     3121 cccaccacgc actgggactc agcagccgct accacccgta ttccaagagc ccgctcccca
     3181 cgcccggtgc cccagtgccg gtgcctgccg ccaccggacc atactactcc ccttatgccc
     3241 tctacggaca gagactgacc actgcctccg cactggggta tcagtgaggg cggcccagag
     3301 gaatttggaa agaggaagga tctgggggat gggaggagcg agggaggggc aggacccgag
     3361 cgaggttcct gacacccgca ggggcagaag acccgggcta cggaagggaa aagaaagttt
     3421 aaatcttacc tatccaccca accacagaga tcgagagagc ctggatgcga aacttctcct
     3481 ccacccctac tcccccaatc aaactttata aaagttgaaa aaaaatcatt tgacttttta
     3541 tagaaaaaga aggaaaacta attgaaaaag tgttcatctg aggacttcgc cggtgaacat
     3601 tggtatttat ttatgttagc tccaagcgga cccgtggttc aaaagtgcat tatttagttt
     3661 gagctccgta ggttaaaagg aggagggggg gaattaaaac tcgagggtaa atatgtggaa
     3721 aacaaaccct ccgatccctt gtagagtata aataaaaaca aagccgctac agaattaggg
     3781 gtcttctctt taatgttact ttaaaattgc tatgattgta ttgtgcgttc ttatttaatg
     3841 tctgattgaa actcaaattt acatgcatgt ttgttacaaa aaagaaatga aaacgacgaa
     3901 acaaaataag tcacaatttg tcaactctga tttcaaattg caattatttt taaggtgtat
     3961 accatcgaaa gagaatgggt atttttttgt atgtattctg gaagaaaaca aaaaaaaagg
     4021 aaaaacaatt ctattccaaa acctcatttg ccttattttg ttctttaaaa ggaacactta
     4081 actattttta atttttaagt ccacccgctg agaaggggac aaggtttacg tcatgtgcta
     4141 aaataataga caatgtatcg ctttaaagat taaaattccg tatatttgat gtattaaaag
     4201 gttttacttc ttaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa a
//
