LOCUS       NM_001362883           12997 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus zinc finger protein 469 (Zfp469), mRNA.
ACCESSION   NM_001362883 XM_006531557
VERSION     NM_001362883.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 12997)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 12997)
  AUTHORS   Stanton,C.M., Findlay,A.S., Drake,C., Mustafa,M.Z., Gautier,P.,
            McKie,L., Jackson,I.J. and Vitart,V.
  TITLE     A mouse model of brittle cornea syndrome caused by mutation in
            Zfp469
  JOURNAL   Dis Model Mech 14 (9) (2021)
   PUBMED   34368841
  REMARK    GeneRIF: A mouse model of brittle cornea syndrome caused by
            mutation in Zfp469.
REFERENCE   3  (bases 1 to 12997)
  AUTHORS   Aboudehen,K., Farahani,S., Kanchwala,M., Chan,S.C., Avdulov,S.,
            Mickelson,A., Lee,D., Gearhart,M.D., Patel,V., Xing,C. and
            Igarashi,P.
  TITLE     Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant
            polycystic kidney disease and regulates mTOR signaling
  JOURNAL   J Biol Chem 293 (24), 9388-9398 (2018)
   PUBMED   29716997
REFERENCE   4  (bases 1 to 12997)
  AUTHORS   Khanam,T., Rozhdestvensky,T.S., Bundman,M., Galiveti,C.R.,
            Handel,S., Sukonina,V., Jordan,U., Brosius,J. and Skryabin,B.V.
  TITLE     Two primate-specific small non-protein-coding RNAs in transgenic
            mice: neuronal expression, subcellular localization and binding
            partners
  JOURNAL   Nucleic Acids Res 35 (2), 529-539 (2007)
   PUBMED   17175535
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC121976.2.
            
            On Feb 2, 2022 this sequence version replaced NM_001362883.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7652917.845786.1,
                                           SRR11927937.2819742.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849382
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-220               AC121976.2         116268-116487       c
            221-286             AC121976.2         87994-88059         c
            287-12997           AC121976.2         74029-86739         c
FEATURES             Location/Qualifiers
     source          1..12997
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 70.85 cM"
     gene            1..12997
                     /gene="Zfp469"
                     /gene_synonym="Gm22"
                     /note="zinc finger protein 469"
                     /db_xref="GeneID:195209"
                     /db_xref="MGI:MGI:2684868"
     exon            1..220
                     /gene="Zfp469"
                     /gene_synonym="Gm22"
                     /inference="alignment:Splign:2.1.0"
     exon            221..286
                     /gene="Zfp469"
                     /gene_synonym="Gm22"
                     /inference="alignment:Splign:2.1.0"
     exon            287..12997
                     /gene="Zfp469"
                     /gene_synonym="Gm22"
                     /inference="alignment:Splign:2.1.0"
     CDS             414..11711
                     /gene="Zfp469"
                     /gene_synonym="Gm22"
                     /codon_start=1
                     /product="zinc finger protein 469"
                     /protein_id="NP_001349812.1"
                     /db_xref="CCDS:CCDS90472.1"
                     /db_xref="GeneID:195209"
                     /db_xref="MGI:MGI:2684868"
                     /translation="MPGERPPTLPRDLQPCQIARSLGCPSQHPLKDHGSASRTTQGMR
                     DDGSKAQGSPEAQLSQAKDVEQEDLILRVQAPAARSYAHVYPWPASRMESGHPQLHSL
                     SPSRIRCILGEPLKDLRHEAPQVSDTKVPQGQKTRARHRPGIPRAKALPSPEENSSQR
                     CFQEASSSFTSTNCTSPSATPGSLPRRAPQSDGTSPHRHASGTNLQAIGTNPWPPAAE
                     NSFPGANFGVSSAEPKPFPDGSRPSSPQGVSAPYPFPVETVQHERAAETMLFTFHQPL
                     VAWSEEALGTNPAYPSLPCNPGPSGGASAPSDLGGALSPPGAARLLPSPFHDSLHKSL
                     TKGIPEGPLPARDGLGSPRGLPNPPPQRHFPGQGYEANGVGTSPASLDTELPTPGPPP
                     THLPQLWDTTAAPPYPTSTLDPAAAARTAFFESQQQLCLPHSPPLPWSPVLTTPGPNS
                     HQMGVLSQLTFPRGSSEWQGDSPGTLGALNTIPRPGESALRSSPGQPSSSPRLLAYGG
                     LKDPGTQPLFFGGAQPQMSPQGALSLPPPRVVGASPSESPLPSPATNTASSSTCSSLS
                     PPSSSPANPSSEDSQQPGPLRSPAFFLPPTHSQETSSPFPSPEPTYTLPTRYQSETAK
                     AFPLPTEGPGAEDAFKSQEGAPFSHKSPSLGRDGLKGFPPEPPPPPPPPPYSAQHFSL
                     SSASLDQLDVLLTCRQCDRNYSSLAAFLEHRPLCSLLLTKTKDGSLQPPGLPTPTTTS
                     KAPTDAHSALLEHNQTVPFLLTRDDPAVTSFPLPTSDLDMEDDAKLDRLITEALNGME
                     YQSDNPEIDSSFIDVFADEEPSGSRGPSTGHPLNNQVGSISKNGTQPQLPSKAAVPEP
                     QAPCTGNRSHPARNRPKTRSLGLASVQADATTLVRQQRRGKQFKLFRKEPGMAKGTNS
                     QAKAICLRPRKKGHSAEHPRPQARKSQTRKGHARADHSISRATSKETRSSKHLQLPSG
                     KDSRKRRGRGGSWSKELIHKIVRQKNRRHGQQAPRNQVSHVPPLPGRPPSTQEGRLSG
                     QGCASESEEEAGMQQRRDLGGPAQGCSPHSRQRWRQGKKRKKEDLTQNPRKVMRQEAG
                     ENGGSPTPRTQSLLPSSEAGEVSVERGLEHRGHPIIAPKHPPRVLATTKTQEKNHAAL
                     DFPQEGEKPEVAADTTELRERPSSPAHCGGESPRPAAPVPARAGSPSGSHPETLSGNS
                     VPVPDAGCLLGTSGCMKPPTLHTREDSASQPGRCLVPIDKLADMFYTESSLPVFKNSS
                     PGCDPDHCDRRSLECPAAKRGSLPNSDTCELFLGSKDLAYCFPDDLYTKPLAMDPLPA
                     RSCYLSQDSMETLESTPSKSPPYPVETDPGKVHSPLTLESTSLFAGLPEDGFDPPLYD
                     NLSANRVTHGPLAGPDPLPKKPLADPLYPPFLLLEEISPVLPGSFPGLSKGKTVSKQC
                     PSEQTVPPRPPAVPEKGSECSNLCEDELEIKRLVTELESQLQGEGSTVGTSGEPEEAT
                     QEGKMDTSPKQASLLPTNPATSAQREPAEDITGLEGSSSHQERALKNPQKQWPYPASC
                     HTEKAAPPCGIQENPGCGAPLSLEGFTLGLQRTRETIIPDADSQIPLSDRLPDSSNQQ
                     VALLHAGSLAKDSPKHGLLFPKNNEAPGTQNSNAPPLLPGKHTRGHSLDPFCEAQEPC
                     PTSPALEGFNSPSAHPALEPNLILKGDEEVTSLPSASLSHGSKGHSEDQAGSSIGAVL
                     NKPIAKDLDFKGASAPAGTSPQSTLQSGGRAWSHPVPDPPWEPSASIGQRRQDPACCS
                     FPLRQVLDATAKSRENAQGLQSGDPSVTGGARMKEDSSRAVNVSALPANIQKQLRSKA
                     DGRLGSPSQPEKIKGQGQANRLQPKSWRSLEDPDALNKVSAHLEARPARGRRPRQGNR
                     AARGLRRQALFSTSPTDPDSTSLLPIQKACPLQKEPAERSPEKAASPQPLFSQENPAP
                     SNRDLAACVFSTRPQATPTPSDLEPMPQEDPETRVKPSKPLAPSSYRDLPSPDDQPTC
                     PVLVPLGASYGLTTKEAEPPASPTLLVTSCCGPEEPLSQHSLLGTSSPKDPPVGSLGS
                     ISFSAPVLLERNSPKGIAVRTLEDSGKEELRLSPAHSSAPPLGDPSSPKMTIEAAPLT
                     SIAPKDGLDSGETLEVPAPHCMGAPSLSNPERTYSKGPSLGPVSSTPCPGHGEGRGII
                     AVPTDLATLETTGPDSQICQEDGADVSIKEQDNPETPGTRHCNVTKVARANARGMPTG
                     LHLTLETPLSGTSSDSRSDSPQYHISISHRPPQKNFSDPQDHKRRPRGLNKKPEHAEQ
                     TPAELPETCQLCSASFRSKAGLSRHKARKHRPQREPRSLLSPMPVPACQPSDPMTKAC
                     QTPGKKSHKVSEKGRPSRPALGAGRSSGPPPLQDTMGPEILKRTSEKSEGAGTLDTPL
                     SQHPPTLGLSEQGESAEVPASKPRRADRWGTNQLHPDQTEVRGKRQGGQPADSPSHPE
                     RKPNRKGVKLRARRQKHGPGGTTHVTSDLPTACGHPLIPLSLSPEGGCRPAVRPPPPS
                     STGGPRALEDAEDVGPGALCTEEVPAQKAPQEHPVCQGTIEKEHPVEQKATWTQWFWG
                     PEEATASDISGEPSRAIESQPTEDHTGVKGRSDEGTGKGTPDLPDRTHSSEVDNTISS
                     YPQGPIKDPETQNEVHGSDGAPSPEQRDPPDLFDDDISFSRLFPLDGRLTQKNLRVYG
                     KRCQRPKCPSPKEPIAEVINSVSLGSTRLPTDLSDSGSLCLSREEEDVWDDEVMSLPE
                     SLLLDGLLSNKTPGLDPWTPSLSLWALESDRQTSCVEEKPSCLMENQDEWSEPIPQLH
                     MVPAAWRDLEHCSPACETASSVGDMSPEPPNLEREHDNRPPGNASLPPLYVKDFEALS
                     TQLEIQDLCFLRPCSDLVELSNPGALDFQVTANSQGPPDKRMEGTARARRAKGRDLRV
                     KGKRASYKCRVCFQRFHSLGELDLHKLSHSPSPPPTCYLCVERRFSSRELLREHLWEK
                     HVQGKAGPWACGMCLKEVADVWMYNQHLREHAARFARNGQARRALGDLPGCLEGESAL
                     THFLNTIVERASKPQRTKRSIGKDSREPSEQEGDAGKKTPRRMKRKARASVTPSQDGA
                     EGGSLSVLTSSSATCSDSAKTPPAPSPDPWSHGESPLQAVPVHEDCKDPSRDCHHCGK
                     QFPKPFKLQRHLAVHSPQRVYLCPRCPQVYPEPWELKVHLGLTHGVTEEKELPHVPLY
                     ACELCANVMHVIRRSFVCSSCNYTFAKKEQFDRHMGKHLSCDLQPFTLRSVKRPGVPR
                     RKTRVSQDVLPSKQNRLMAPFSPPELSTDRIPSTTSPTPSEVSLPALPLAPSLILDQP
                     SSQENPVDQADHSPRGNNLPLSGQDLPPPSLSPFSAASAEGTGGCCKLNRTLEKPEHE
                     ASLGSLEPCKWQALVGEKRALHLFPGKHKSPGNGDKCAPGCSPGHPSQLQERLVTTHH
                     MAPEGRIEGPSQKGNATKPGAYSSTSHHRAAEPTKKALKPPAPPRKPGGMGIPAAELV
                     LSPEDRVKPNTSKGKLRGTPQSSGGLQPGTQTGGGSQPQPTSGQLQSEMASTPTEPSC
                     PSWASSTPDQPPPRAHTKGSTRGPGDAVHQGVQVHSSPREKRESHGRQRKGQALGLGR
                     HGSVGNTGKAPLAPDKSSRAPRKQATPSRVPPVKSRPSGQSSRARPQPSAQRKGDPGH
                     TSEKGSLPQARALSRPYKRVRALHVSGVAPMEPRDRRTAEAQSDLLSQLFGQKLTSFR
                     IPLKKDSSQ"
     regulatory      12972..12977
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp469"
                     /gene_synonym="Gm22"
                     /note="hexamer: AATATA"
     polyA_site      12997
                     /gene="Zfp469"
                     /gene_synonym="Gm22"
                     /note="major polyA site"
ORIGIN      
        1 gtgcgtccgg cctccgcgcg agcgctgccc gcggaccggc ccgggaggcg gccctctgct
       61 cgcaccccgc cccaggcgca gcgcggcggc tcggtgcccg gcggacgggc gggcgggcgg
      121 ccggggcgct gcgggcgggg atgagcgctg gggctacgcg gtccgggcgc gggcgccccg
      181 cgcgtcccgg gaactggagc tacgcgcggc cggggcggag acaagaaggt cccattcctc
      241 aggcagttgt tcagaagaag accactgagg ggccccagat acccaggctc cacacaggac
      301 catgagtata ggcttccgtg agccccgcca gggggtgagg atggccaggc agcccattac
      361 ctgggctcct cctccaatca ctacatcctc ctagcatccg ggacggcggg gccatgccag
      421 gagagcggcc cccaactttg cccagagact tacagccctg ccaaattgcc aggagtctag
      481 gatgcccctc tcagcacccc ctcaaggacc acggctctgc cagcaggacc acccagggca
      541 tgagagatga tggcagcaag gcccaaggtt ccccggaagc ccagctgagt caggccaaag
      601 atgtggagca agaggacctg atcctgagag tgcaggcccc agcagcacgg agctatgcac
      661 atgtttaccc atggccggcc agcaggatgg agagcggcca cccccagctc cacagcctga
      721 gtccttcgag gatcagatgc atcctgggtg agccgctcaa ggatctgcgt catgaagccc
      781 cccaggtgtc agataccaag gttcctcaag gccaaaagac cagagcccgc cacaggcctg
      841 gcatcccaag ggccaaggcc ctgccctccc cagaagagaa tagctcccaa aggtgctttc
      901 aggaggcctc ttccagcttt acctccacca actgtacctc accaagtgcc acccccgggt
      961 ccttaccccg gagggccccc cagagcgatg gcaccagccc ccataggcat gcttctggca
     1021 ctaacctcca ggccattggg accaacccct ggcctcctgc tgctgaaaac agcttcccag
     1081 gtgctaattt tggggtctcc tctgcagagc ccaagccctt ccctgatggc agcaggccta
     1141 gcagccccca gggggtctct gccccctacc ccttccctgt agagacagtc cagcatgaga
     1201 gggcagctga gacaatgttg ttcaccttcc accagcccct ggtagcatgg tctgaggagg
     1261 ccctgggtac aaaccctgcc tacccatccc tgccttgcaa cccgggcccg tcagggggag
     1321 ccagcgctcc cagtgatctc ggaggtgccc tctcaccacc tggtgctgct cgcttgctcc
     1381 cgagcccctt ccatgatagt ttgcacaaaa gcctgaccaa aggcattcct gaagggcccc
     1441 ttcccgctcg cgatgggctg gggagcccca gaggcctccc aaatcctcca ccccagaggc
     1501 actttccagg gcaggggtat gaagcgaatg gggtgggtac cagcccagca tcgctggaca
     1561 cagaactgcc cacccctggg ccaccaccca cccatctgcc ccagctgtgg gatacaacag
     1621 cagctcctcc ttaccccacg tctaccctgg accctgcagc tgctgccagg actgccttct
     1681 tcgaaagcca gcagcagctc tgcctccccc acagtccccc gctgccctgg tccccggtgc
     1741 ttaccacccc tgggccgaat tcccaccaaa tgggggtact gagccaactg acattcccca
     1801 gggggtcttc tgagtggcag ggggacagcc cgggaaccct gggtgctttg aatacaatcc
     1861 ccaggcctgg agagtcagct ctcaggagca gcccaggcca gccaagcagt tccccaaggc
     1921 tgctagccta tggtgggctg aaggaccctg ggacacagcc cctgttcttt gggggagccc
     1981 aaccccaaat gtcaccccag ggggccctca gcctgccccc acctagggtg gtgggggctt
     2041 cacccagtga atctcctctt ccctcacctg cgaccaacac agccagcagc agtacctgtt
     2101 catctctgtc accgccatcc agcagcccag ccaaccccag ctctgaagac agccagcagc
     2161 ctggacccct caggtcccca gccttcttcc tgcctcccac ccattcccag gagaccagca
     2221 gccccttccc ttccccagag cccacataca ccctgcccac acgctatcaa tccgagacag
     2281 ccaaagcctt ccctctcccc acagagggac caggggctga ggatgccttc aagagccagg
     2341 agggagcccc attctcccac aagagcccct cactgggcag agacgggttg aagggctttc
     2401 ctccagagcc accacctcca ccgccaccgc caccttactc agcccagcac ttctccctga
     2461 gcagcgccag cctggaccag ctggatgtcc tactgacctg cagacagtgc gatcgaaact
     2521 atagcagcct cgcggccttc ctggaacaca ggccactctg cagcctcctg ttaaccaaga
     2581 ccaaggatgg ctctctgcag cccccagggc tccccacacc caccaccacc tcaaaggcac
     2641 ccaccgatgc acactcggcc ttgcttgaac acaaccagac tgtccccttc ctgctaacca
     2701 gagatgaccc agctgtcacc tccttcccac tccccacctc ggaccttgat atggaagatg
     2761 acgctaagct ggacaggctc atcaccgagg ctctcaacgg catggagtac caatcagata
     2821 atcctgagat agacagcagc ttcattgatg tctttgctga tgaggagcct tcaggctcca
     2881 gggggcccag cactgggcat cccctcaaca atcaggtggg atcaatttcc aagaatggta
     2941 cccagcccca gctcccatcc aaagctgctg tgccagaacc ccaagccccc tgcactggaa
     3001 acaggagcca cccagcccga aacaggccca aaacccgttc cctgggcctt gcatctgtac
     3061 aggcagatgc gaccaccctg gtcaggcagc agaggagagg gaagcaattc aagttgtttc
     3121 ggaaagagcc cggtatggcc aagggtacta acagtcaggc caaagccatc tgcctgaggc
     3181 caagaaagaa gggtcacagt gcagagcatc cccggcccca ggctcgcaaa agtcagactc
     3241 gcaagggcca cgctcgtgca gatcacagca tctccagagc cacctccaaa gagacgagga
     3301 gctccaagca cctgcagctg ccctctggga aggactccag gaagaggagg gggcggggcg
     3361 gctcctggag caaggaactc atccacaaga tagtgcggca gaaaaacagg cgccacgggc
     3421 agcaggcacc acggaaccaa gtctcccatg tccccccgct gcctggaaga ccacctagca
     3481 cccaggaggg caggctcagc gggcaaggct gtgcctctga atctgaggaa gaggctggta
     3541 tgcagcagcg gcgggatttg gggggtcctg cccaaggctg ttccccccac agccgccaac
     3601 ggtggcgcca gggcaagaag aggaagaaag aagatttgac ccagaaccca aggaaggtca
     3661 tgcggcagga ggctggtgaa aatgggggct ctcccactcc aaggactcaa agcctgttgc
     3721 cgagttcgga agctggagaa gtctctgtgg aaagaggact tgagcatcgt ggccatccca
     3781 taatagcccc aaaacatcct ccccgggtcc tcgccaccac caagacccag gagaaaaacc
     3841 atgcagccct ggacttcccc caggagggcg agaagcctga agttgctgct gataccactg
     3901 agctcagaga gagacccagt tctccagctc actgtggtgg ggaaagcccc agacccgctg
     3961 ctccagtgcc agcacgggct ggcagtccat cagggagcca ccctgaaaca ctatcgggaa
     4021 acagcgtgcc agtaccagat gcaggctgtc ttctgggcac ttctggatgc atgaagcccc
     4081 cgactttgca taccagagag gactctgcct cccagcctgg aaggtgcctg gtacccatcg
     4141 ataagctggc agacatgttc tacactgaat ccagcctccc ggttttcaag aactcgagtc
     4201 ctggttgtga ccctgaccac tgtgacaggc gctctctaga gtgtccagct gccaaaagag
     4261 gatccctgcc taacagtgac acctgtgaat tgttccttgg atccaaggac ctagcctact
     4321 gtttccctga cgatctgtac accaagcctt tagctatgga cccgttgcct gcccgaagct
     4381 gctaccttag ccaggacagt atggagaccc ttgagtcaac accatccaag agtccaccct
     4441 acccagttga aacagaccca gggaaggtgc attcgccact gaccttagag tccacatccc
     4501 tgtttgcagg gctgcctgag gacggatttg acccaccact ctatgacaac ttgtcagcaa
     4561 acagggtcac ccacggacca ctggcaggtc ctgaccctct ccctaagaaa cctctggcag
     4621 atcctctgta cccgccattc ttgctgctgg aggaaatttc tccggtgctg cctggctcct
     4681 ttcctggtct ctccaaggga aagacagtca gcaagcagtg tccctcggaa cagacggtgc
     4741 ctccccgccc tcccgctgtg cctgaaaagg gaagtgaatg tagcaatctg tgtgaggacg
     4801 aactggagat caaaagattg gtgactgaat tagaaagcca actgcagggg gaagggagca
     4861 cagtgggcac ctcgggagaa ccggaggaag ctacacagga aggcaagatg gacacaagcc
     4921 caaagcaggc ctcccttcta cccacaaatc cagccacctc agcccagagg gagccagcag
     4981 aagacattac aggtcttgag ggatcaagtt cacatcagga aagggccctg aagaaccccc
     5041 agaaacagtg gccctaccca gcttcctgcc acacagaaaa agcagcacct ccctgtggta
     5101 tccaggagaa cccaggatgc ggggctcccc tcagcctgga aggattcaca ctcggtcttc
     5161 agagaactcg ggagaccatt atccccgacg cagacagtca gatcccccta agtgaccgcc
     5221 tgcctgactc cagcaaccaa caggtggcct tgctgcatgc tgggagttta gccaaggaca
     5281 gcccgaagca tgggcttttg tttcctaaaa ataatgaagc ccctgggacc cagaactcga
     5341 atgccccacc gctgcttcct ggtaaacaca caagaggaca ttctctagac ccattctgtg
     5401 aggcccagga gccctgccca acttcccctg cactggaagg attcaacagc cccagtgccc
     5461 acccggccct agaacccaac ttgatactta agggtgatga ggaagtcacc tcccttccaa
     5521 gtgccagtct cagccatggc tctaagggtc actctgaaga ccaggcaggg agttctatag
     5581 gagctgtgct taacaagcct attgccaagg acctggactt taagggggcg tctgcacctg
     5641 cagggacctc tccacaatcc acccttcaaa gtggtggtag ggcttggtct catcccgtgc
     5701 cagatcctcc ctgggagccc agtgccagca ttggacagag gcgccaggac ccagcctgct
     5761 gttcctttcc tctgcgtcag gtcctggatg ctacagccaa gagcagagag aacgcccagg
     5821 gccttcagtc tggggacccc tcagtgacag gaggggcccg tatgaaagag gactcctcaa
     5881 gggctgtaaa cgtgtcagct cttcctgcaa acatccagaa gcagctgagg tccaaggcag
     5941 atggacgtct tggctcgcct agtcaacctg aaaagatcaa gggccagggt caagccaaca
     6001 gactccagcc aaaaagctgg aggagcctgg aggacccaga tgcactcaac aaggtcagtg
     6061 cccatttgga agctaggccg gccaggggca gaaggccacg ccaggggaac agagcagccc
     6121 ggggccttag gagacaagca ctgttctcca ccagccccac cgaccctgat agcacatcct
     6181 tgcttccaat ccagaaggct tgccctctcc agaaggagcc tgcagagaga agcccagaga
     6241 aggccgccag cccacagcca ttgtttagcc aggagaatcc cgctccctcc aatagagacc
     6301 tggccgcatg tgtcttctcc accaggcctc aagccacacc tactcccagt gaccttgagc
     6361 cgatgcccca ggaagaccct gagaccagag tcaagcctag taagccacta gcaccttcct
     6421 cctacagaga cctacccagc cccgatgatc agccaacctg tcctgtcttg gtacctctgg
     6481 gtgccagtta tggcctaacc accaaagagg ctgaaccccc agcatcccct acactattgg
     6541 tgacaagctg ctgtggccct gaagagcctt tatcccagca ctctctgctg gggaccagca
     6601 gtcccaagga ccctcccgta ggctcacttg gctccatcag tttctcggcc cctgtattac
     6661 tagagaggaa cagccccaag ggcatcgcag taagaacatt agaagattct ggaaaagagg
     6721 agctgaggct atctcctgcc cattcctccg ctcctcccct aggggatccc agctccccta
     6781 aaatgaccat cgaagctgcc cctctgacca gcattgcccc caaagatggc ctagattcag
     6841 gtgagacact tgaggtgcca gccccccact gcatgggagc cccatccctc agcaacccag
     6901 aaaggacata ctccaagggc ccttccttag ggcctgtgag cagcactcct tgccctggcc
     6961 acggggaagg ccgcggcatt atagctgtgc ccacagacct tgccacactg gagactacag
     7021 ggccagactc tcaaatctgc caagaagatg gggcagacgt cagcatcaag gaacaggaca
     7081 acccagaaac acctgggaca agacactgca atgtgacaaa ggtagccaga gccaatgccc
     7141 gaggcatgcc cacagggctc cacttgaccc tagaaactcc tctgagcggc acatccagcg
     7201 actccaggtc tgactctcct cagtaccaca tcagtatctc ccatcgccct ccccagaaga
     7261 acttctccga cccccaagac cataaacgga ggccccgtgg actgaacaaa aagccagagc
     7321 atgcagagca gaccccagct gagctacccg agacctgcca gctctgctca gcctccttcc
     7381 gctccaaagc gggcttaagc cggcacaaag ccaggaagca ccggccacaa agggaaccta
     7441 gatccctgct gagccccatg cctgtgcctg cttgccagcc ttcagatccc atgaccaaag
     7501 catgccagac tcctgggaag aaaagccaca aggtgtctga gaagggaaga ccgagtcgcc
     7561 cggccctggg ggctggccgc tcttctggac cacctcccct ccaggacacc atgggtcctg
     7621 agatactaaa aaggactagt gagaaatctg agggagctgg gacactagac actcccctca
     7681 gccagcaccc acccacccta ggcctcagtg agcaaggaga gagtgcagag gttcctgcct
     7741 caaaaccaag gagagcagac agatggggaa caaaccagct ccatcctgac cagacagaag
     7801 tgaggggcaa gaggcaaggt ggacagcctg ccgattcccc cagccaccca gagaggaaac
     7861 ctaacaggaa aggggtaaag ctgagggcaa ggaggcagaa gcatggtccc ggaggcacta
     7921 cccacgtgac ttcagaccta ccaaccgcct gtggccatcc tctcatcccc ctgagcctct
     7981 cgcctgaggg aggatgcagg ccagctgtca ggcctccacc tccatcctcc acaggaggac
     8041 ccagagcact ggaagatgct gaagacgttg gtccaggggc cctgtgtaca gaggaggtac
     8101 cagcacagaa ggccccccaa gagcatccgg tctgtcaagg gacgatagag aaggagcatc
     8161 cggtggaaca gaaggccacc tggacacagt ggttctgggg accagaagag gccacggcat
     8221 cggacattag tggagaacct tcacgggcta ttgagagcca gcctacagag gaccacacag
     8281 gagtcaaagg caggtccgat gagggcactg ggaaagggac acctgactta cctgacagga
     8341 cacacagttc tgaagtggac aacaccatca gtagctaccc ccagggacct atcaaagacc
     8401 cggaaaccca gaatgaagtc cacgggtcgg atggcgcccc cagcccagag caaagggacc
     8461 ctccagactt gttcgatgat gacatctcct tctctcggct cttccccctg gatggccgcc
     8521 tcactcagaa gaacctacga gtctatggga agcgctgcca aaggccaaag tgcccatcac
     8581 cgaaggagcc catcgctgag gtgataaaca gtgtctcact cggctccacg cgcctgccta
     8641 ccgatctcag tgactcgggc tctctctgcc tgtcccgaga ggaagaggat gtgtgggatg
     8701 atgaagtcat gagtttgccc gagtccctcc tcctcgatgg ccttctaagc aataagacac
     8761 ctggccttga cccatggacc cccagcctca gcctgtgggc cctggaatcc gacaggcaaa
     8821 ccagctgcgt ggaggagaag ccttcctgct tgatggagaa ccaagatgaa tggtcagagc
     8881 ccatcccgca gctgcacatg gtcccagcag cctggcggga cctggaacac tgtagcccag
     8941 cctgtgagac agcctcttct gttggagaca tgagcccgga accccctaac ctagaaaggg
     9001 aacatgacaa caggcctcct ggaaatgcca gcctgccccc actttacgtt aaggactttg
     9061 aggctctcag cacccagctg gagatacaag acctgtgctt tctgagaccc tgtagtgacc
     9121 ttgttgaact ctctaaccca ggcgccctag acttccaggt cacagcaaat tcacaaggcc
     9181 ctccagacaa aagaatggag ggaactgccc gggccagacg agccaaaggc agagacctgc
     9241 gggtgaaggg caagagggcc tcctacaagt gcagggtgtg cttccagcgg ttccatagcc
     9301 tgggcgagct ggatctccat aagctgtcgc acagcccctc gccgccccca acttgctacc
     9361 tgtgcgtgga gcgcagattc agttcccggg agcttctacg ggagcacttg tgggagaagc
     9421 acgtgcaggg caaagcaggg ccgtgggcct gtggcatgtg cctgaaggag gtggctgatg
     9481 tctggatgta caaccagcac cttcgggagc acgcagcccg ctttgcccga aatggccagg
     9541 cgcggcgagc cttaggagac ctgcccgggt gcttggaagg ggaaagcgcc ctcacgcact
     9601 tcctgaacac cattgtggag cgagcatcca aaccccagag gaccaagcgc tcgatcggca
     9661 aagacagtag ggagccatca gagcaggaag gagacgctgg aaagaaaacc ccaagaagga
     9721 tgaagcgcaa ggcacgtgcc tcggtcaccc ccagccaaga tggcgccgaa ggaggcagcc
     9781 tatccgttct gaccagcagt tctgccacct gctctgactc tgccaagacg ccccccgccc
     9841 cgtccccaga cccttggtcc cacggcgagt ccccgctcca agctgtacca gtgcacgagg
     9901 actgcaagga cccctcccgt gactgccacc actgtgggaa gcagttcccc aagcccttca
     9961 agctgcagcg ccacctggcg gtgcacagcc cacagcgcgt ctacctgtgt ccccggtgcc
    10021 cgcaggtcta ccctgagccc tgggagctga aggtacacct gggcctgacc cacggggtga
    10081 cagaggagaa ggagctccca cacgtgcctc tctatgcctg tgagctctgc gccaatgtca
    10141 tgcacgtcat caggaggtcc tttgtctgca gctcctgcaa ctacaccttt gcaaagaagg
    10201 agcaattcga caggcacatg ggcaagcacc tgagttgcga cctgcagccc ttcacactcc
    10261 ggagtgttaa gcggccaggg gttcctagga ggaagacccg tgtctcccag gatgtgctac
    10321 ccagcaagca gaacaggctg atggcgccct tcagtccccc tgagctcagc actgacagaa
    10381 tcccctccac aaccagccct acaccaagtg aggtgtccct tcctgcactg cccctagcgc
    10441 ctagcctcat cctggaccag cccagttctc aagagaaccc tgtggaccag gcagaccact
    10501 cacccagggg gaacaaccta ccactgagtg gccaggatct tccacctccg tctctgtctc
    10561 ctttctcagc tgcctcagct gaaggtacag gcggctgctg caagctgaac agaaccctgg
    10621 agaaaccaga acacgaggct tccttgggaa gccttgagcc atgtaaatgg caggctctgg
    10681 taggggaaaa gagggccctt cacctgttcc caggaaaaca caagagtcca ggcaacggag
    10741 acaagtgtgc ccctgggtgt tccccagggc acccctctca gctccaggag aggctagtga
    10801 ccacacacca catggcacct gaggggagaa tagagggtcc ctcccagaag ggcaatgcca
    10861 ccaaaccagg agcctactca agtacctccc atcacagagc agcagagccc accaaaaaag
    10921 cactgaagcc accagcacca ccccgaaaac caggagggat ggggatccca gccgcagagc
    10981 tggtcttgag tcctgaggac agggtaaagc ccaacacttc taaaggtaaa ctgcgaggca
    11041 cccctcagag cagtggaggg ctccagcctg gcactcagac agggggtggc agccagcccc
    11101 agccaaccag tgggcagctc caaagtgaga tggcctccac ccctactgag cccagctgtc
    11161 ctagctgggc gagctccacc ccggaccagc ccccacctcg agcccacacc aagggtagca
    11221 ccagagggcc tggggacgct gttcatcagg gggtccaagt gcattcaagt cccagggaga
    11281 aaagagaaag ccatggaaga caaaggaagg gccaggccct gggactgggc agacatggaa
    11341 gcgtgggaaa cactgggaaa gcccccttgg cccccgacaa gtcatccagg gccccccgaa
    11401 agcaagcaac tcccagccga gttccccctg tcaagtcgag acccagtggc cagagcagca
    11461 gggcaaggcc acagccatca gcacagcgga aaggggatcc aggccacact tcagaaaagg
    11521 gctctttgcc ccaggcaaga gccctgtcca ggccctacaa aagggtcaga gctctccatg
    11581 tcagtggtgt tgcgcctatg gagccccgag accgccggac tgcagaagcc cagagcgacc
    11641 tcctcagtca gctgtttggg cagaagctga ccagcttcag aatccctctg aagaaggaca
    11701 gttcccagtg acccaaaaga gaggatgcgt gggtgcccgg ctgatgggct tctgtctggc
    11761 ctccagcatt ggagacagct ccctggtaga cccactgcct gtttctctgc acctgagttt
    11821 ccagattcga ggcctgagaa cagggctttg gctggaaggc tgggaaggac cggtctctac
    11881 cgcccaggga tcacctgctt ccctagtgtc aagtacttga agagagcagg ttgcatccca
    11941 tcaccgccac cacaccctgt tggccaggtg tctcgtgctg taaagcttgt gtttgagggt
    12001 ttgcacaggg ttccccgtct cttagcaggg aagcacacag tggcagctgc cttttctgct
    12061 gccattgtta aaattccaaa gtgtcatggg agagggccat gctgtctact tgggccattt
    12121 ctgagccacc tggtctttga cagcatgaca ggaccaccct cccccacccg caaccacaaa
    12181 atcgcgctgg cctccagctg cactgctgat ctctgcagca ccttgtcccc accccacccc
    12241 accccccacc cctggaactg ggttcctata gggaatgcaa gaaggccctt catggccagc
    12301 atcctgtggg tccctcagcc ctacggcccc ttcctagtgc cttctttccc catggggctc
    12361 caactctagg tcccagaaag cctggtccaa aggctctggt gctactcccg tgctgtaatg
    12421 tgaatacagg ctccctggtc ttctttgaac cacgggatga ttagagtggg gagacctagc
    12481 cagagaggct gcagcccagg actcaagaga gagcctcatc caccggtctc cccagttgag
    12541 ctccagccca gggtcccagc agtgaaggga ccccccaggc tgggctgtgg gtctggtctg
    12601 tgcactggca caagcctgcc aactgcacac ctgcctgata tagcgttgtg tatcaaagtg
    12661 ggcagaggga gaggtttccc attcctccta ggagtcttag agattcctgc cttactttgt
    12721 tgtgtagttt gttggctttt tggggttttc ttgttttttg tatttttgtt cttgtttttg
    12781 ttttttagct ttggtgcaat gtgagtgtca aaaggtttta ttttgacatt ttaaacaaga
    12841 ccaaatcagg cccaaactgc ctccatagaa ggtgctgggg tctttcagaa tgcctccttc
    12901 caatggataa agacgtgggc agcccccccc ccaggttgta ctgtaaaagc tacagctaat
    12961 ttgtcttttc aaatatattc ccactatttt cgcagaa
//
