LOCUS       NM_178722               3209 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus zinc finger protein 438 (Zfp438), transcript variant
            1, mRNA.
ACCESSION   NM_178722
VERSION     NM_178722.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3209)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3209)
  AUTHORS   Guo,G., Huss,M., Tong,G.Q., Wang,C., Li Sun,L., Clarke,N.D. and
            Robson,P.
  TITLE     Resolution of cell fate decisions revealed by single-cell gene
            expression analysis from zygote to blastocyst
  JOURNAL   Dev Cell 18 (4), 675-685 (2010)
   PUBMED   20412781
REFERENCE   3  (bases 1 to 3209)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK034745.1 and AK046812.1.
            
            On Sep 9, 2009 this sequence version replaced NM_178722.4.
            
            Transcript Variant: This variant (1) represents the longer
            transcript. Both variants 1 and 2 encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK046812.1, AK034745.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849382
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2861              AK034745.1         2-2862
            2862-3209           AK046812.1         2858-3205
FEATURES             Location/Qualifiers
     source          1..3209
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 3.02 cM"
     gene            1..3209
                     /gene="Zfp438"
                     /gene_synonym="9430031G09; 9430091M14Rik; B830013J05Rik"
                     /note="zinc finger protein 438"
                     /db_xref="GeneID:240186"
                     /db_xref="MGI:MGI:2444919"
     exon            1..94
                     /gene="Zfp438"
                     /gene_synonym="9430031G09; 9430091M14Rik; B830013J05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            95..172
                     /gene="Zfp438"
                     /gene_synonym="9430031G09; 9430091M14Rik; B830013J05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            173..240
                     /gene="Zfp438"
                     /gene_synonym="9430031G09; 9430091M14Rik; B830013J05Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             204..2600
                     /gene="Zfp438"
                     /gene_synonym="9430031G09; 9430091M14Rik; B830013J05Rik"
                     /codon_start=1
                     /product="zinc finger protein 438"
                     /protein_id="NP_848837.3"
                     /db_xref="CCDS:CCDS37721.1"
                     /db_xref="GeneID:240186"
                     /db_xref="MGI:MGI:2444919"
                     /translation="MRNSSSVPPKDQGESNIRSGTTQSGKTLQSKSQFRTIAPKVVPK
                     VLTSRVLPCPSSISDQGSLTLMPKPLGMPTQNYALMQVAGQEGTFSLVAFPNVASAQP
                     VQKPRMSTHENLKLPIPRYQPLSSQGLRKKQDLSSPKSGSSDPPGPSQLCHLTSSPQA
                     YPDPHHKPSLWKQMPTLNPSPTNINTATLTSGVGQGDLSPLVTNSCGDLELSAMPVYT
                     TEDSSSQQSLPASMQKAGCARKEAPTTPAIASEELKEQLASAQTVLSSAVQLLSVVPK
                     GKLPILPLPRVKTTEVGKVESDADNAELSLSGCRANCDERLSITEGFDAATEIASKIA
                     ALHGSKQSACESAFCPVTKLDLSHKAKPSSGIKRRGRKWKVPDEILALQGKRRKCIIG
                     MCGDGIERARNSPQEARDQKPRVASRKYRNIMPKPVLVLSALAPLASHTAVLSQAPSS
                     LGQDVLNNALPSKCLGSKQSDSSTPKPSSVLRNGFSGIKKPWHMCPVCNYHFQFKHHL
                     LDHMNTHTNRRPYSCGICRKTYVRPGSLSAHMKLHHGDNHPKKLVCCEFCAKVFGHVR
                     VYFGHLKEVHRVVISTEPSPSELQPGDTPKNKNRDPGMQGPDNSLERETKSSLEEDFL
                     LNQADEVKLQIRCGRCQITAQSFAEIKFHLLHVHGEEIQGRLQEMILPGSRSDAPHQK
                     QYTERRKQMKPYASLEDSPAFPRVKRLPAPHQNREEALVGSEGGQWGMAGSQHPAKLL
                     WSHTGFNCLLCAQMLGRKEDLLLHWVHKHNCEDPSRLWALLGKFSKQGAPELHSESRL
                     "
     exon            241..2041
                     /gene="Zfp438"
                     /gene_synonym="9430031G09; 9430091M14Rik; B830013J05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2042..3209
                     /gene="Zfp438"
                     /gene_synonym="9430031G09; 9430091M14Rik; B830013J05Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2841..2846
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp438"
                     /gene_synonym="9430031G09; 9430091M14Rik; B830013J05Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2870
                     /gene="Zfp438"
                     /gene_synonym="9430031G09; 9430091M14Rik; B830013J05Rik"
                     /note="major polyA site"
ORIGIN      
        1 ggggcctagg ccggagcgct gcgcccgcgg gctgacctcg ttgaagtcga cccatgacgt
       61 caccccgccg tgacgcgtac gcagtaggaa aactataaag atggatgtca tgcattattc
      121 agtatggaag tttcagaagt tagaagacat ttgctaaatc aagttacttc acgaaagcta
      181 ctcttcgggt catatacatc ataatgcgga attcttcatc agtaccacca aaagatcaag
      241 gtgaatcaaa catccgttct ggaacaacac agagtgggaa aacattacag agtaagagtc
      301 agtttaggac cattgcacca aaagttgtac ctaaggtcct aacatccaga gtgcttccct
      361 gcccttcctc aatttctgac caagggagtc tgactctaat gcccaagcct ctgggcatgc
      421 ccacccagaa ctatgctctg atgcaggtgg ctggccaaga ggggacgttt tctcttgttg
      481 ctttcccaaa tgttgcctca gcccagccag ttcagaagcc cagaatgtcc acacatgaaa
      541 accttaaact gcctattcct cgataccaac cactaagtag ccaaggatta agaaagaaac
      601 aggacctgag ctctcccaag agtggctcca gtgaccctcc tggcccatcc cagctatgtc
      661 atttgacctc ttccccacaa gcctatcctg atcctcatca caaacctagc ctgtggaagc
      721 aaatgccaac tttaaaccct tctcccacca acatcaacac agctacactg accagtggtg
      781 ttggccaagg agatttgagt cctctagtga ccaacagctg tggcgatctt gagctttctg
      841 ccatgccagt gtacactaca gaggactctt cttcccaaca gagcctccca gcaagtatgc
      901 agaaggcagg ttgtgccagg aaggaggcac ccactacacc tgctattgct agtgaagaac
      961 tcaaagaaca gttagcttct gcacagactg tcttgagcag tgcagttcag ttgctctctg
     1021 tagtacccaa gggtaaactg cccatcctgc ccttaccaag agtgaaaact acagaggtgg
     1081 gcaaagtgga atcagatgct gataatgcag aattgtcttt atctggatgc agagcaaact
     1141 gtgatgagag actgtccatc acagaagggt ttgatgcagc cacagaaata gccagcaaga
     1201 tagctgcttt gcatgggtct aagcagagtg catgtgaaag tgccttctgt cctgtcacca
     1261 aattggatct cagccacaag gcaaaaccca gcagtggaat aaagagaaga ggaagaaaat
     1321 ggaaagtgcc agatgagatt ttagcattgc agggcaaaag gaggaaatgc attattggta
     1381 tgtgtggaga tggcatagaa agagcaagaa acagtcccca agaagccaga gaccagaagc
     1441 ccagggttgc ttcaaggaag tatcgtaaca tcatgcccaa gcctgtcctt gtcctgtctg
     1501 ctttggcacc cctggcgtct catacggctg tgctgtctca ggctcccagc agcctaggtc
     1561 aagatgttct gaataatgcc ctgccttcaa aatgtcttgg ctccaagcaa agtgacagct
     1621 ctacccctaa gcccagctct gtactccgaa atggattctc tggcattaaa aagccctggc
     1681 acatgtgtcc agtctgcaac taccactttc aattcaaaca ccaccttcta gaccacatga
     1741 atacacacac caacagacgg ccttatagtt gcgggatctg tcgcaagacc tatgtgcgcc
     1801 ccggcagcct gagtgcacat atgaaacttc accatggtga caaccacccc aagaaactag
     1861 tgtgctgtga attttgtgca aaagtatttg gtcatgtccg agtctatttc ggccatctga
     1921 aggaggtgca cagggttgtg atcagcacag agccctcccc cagtgaactg cagccaggag
     1981 acacaccaaa aaacaagaac agagatcctg gtatgcaagg acctgacaac tcactggaga
     2041 gggaaaccaa gtcaagtttg gaagaagatt ttcttctaaa ccaggcagat gaagtcaaat
     2101 tgcaaatcag atgtggccgt tgtcagatca ctgctcagtc ttttgctgaa ataaagtttc
     2161 atttgcttca tgttcacgga gaggaaattc aaggtcggct gcaagagatg atcctaccag
     2221 gcagcagatc ggatgctccc caccagaagc agtacacaga gaggaggaag caaatgaagc
     2281 cctatgcctc tctggaggac tctccagcat tccctagagt gaaaagactg ccagcccctc
     2341 atcagaacag agaggaagcc ctggtaggaa gtgaaggtgg ccagtgggga atggctggct
     2401 cccagcaccc cgccaagctt ctctggtccc acacaggctt taactgcctg ctctgtgctc
     2461 agatgcttgg gcggaaggag gacctgcttc ttcactgggt acacaagcac aactgcgagg
     2521 accccagcag actctgggct ctcctgggaa agttctctaa gcagggtgct cctgagctcc
     2581 acagtgaatc caggctgtga tgctgaggcc atccagccca agagatgctg caccaccttt
     2641 ctcactgcct gtgctgctag gatttagtta taaggatcca gtactccagg gccagggcca
     2701 gtgtacagag gaagtacact gtgcgtagtt atattttctt aagaaataaa atatgtgccc
     2761 tggatgcatt tttctaacat atgtagtctc actttaaaat tccatgcatt ctccaatatc
     2821 gtagacttta tttaataata aataaaaaga tcaaaattag gaaactgaaa tgtagagaaa
     2881 attgttattc tcaattgcaa gcctttgagt atgagtgtgt atgtatttgt tttctttgtt
     2941 tgtgtgtgtg tgtgtatgtg tgtgacagag agtgacagag agagagagca acagagaggg
     3001 aatatatgta catgtgtcct tttattttga tgctatttga ttatatttat taacagttaa
     3061 ttctacagct gtggaatata gtcccaactg tagtataaag ttatatgata aatgttgata
     3121 tttattagtc tctggtttat ttgcatatgc cctagaacag tcttttgaaa aatgtactct
     3181 ctaccataac ataaaatctg tttcaagac
//
