LOCUS       NM_146179               2700 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Mus musculus zinc finger protein 418 (Zfp418), mRNA.
ACCESSION   NM_146179
VERSION     NM_146179.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2700)
  AUTHORS   Singh,S.R., Meyer-Jens,M., Alizoti,E., Bacon,W.C., Davis,G.,
            Osinska,H., Gulick,J., Reischmann-Dusener,S., Orthey,E.,
            McLendon,P.M., Molkentin,J.D., Schlossarek,S., Robbins,J. and
            Carrier,L.
  TITLE     A high-throughput screening identifies ZNF418 as a novel regulator
            of the ubiquitin-proteasome system and autophagy-lysosomal pathway
  JOURNAL   Autophagy 17 (10), 3124-3139 (2021)
   PUBMED   33249983
REFERENCE   2  (bases 1 to 2700)
  AUTHORS   Pan,L., Sheng,M., Huang,Z., Zhu,Z., Xu,C., Teng,L., He,L., Gu,C.,
            Yi,C. and Li,J.
  TITLE     Zinc-finger protein 418 overexpression protects against cardiac
            hypertrophy and fibrosis
  JOURNAL   PLoS One 12 (10), e0186635 (2017)
   PUBMED   29065170
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2700)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC150745.2, AK039147.1 and BB671687.1.
            
            On Jan 31, 2007 this sequence version replaced NM_146179.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC024761.1, AK039147.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-39                AC150745.2         74639-74677         c
            40-2697             AK039147.1         2-2659
            2698-2700           BB671687.1         431-433
FEATURES             Location/Qualifiers
     source          1..2700
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 4.16 cM"
     gene            1..2700
                     /gene="Zfp418"
                     /gene_synonym="A230102I05Rik; ZNF418"
                     /note="zinc finger protein 418"
                     /db_xref="GeneID:232854"
                     /db_xref="MGI:MGI:2444763"
     exon            1..206
                     /gene="Zfp418"
                     /gene_synonym="A230102I05Rik; ZNF418"
                     /inference="alignment:Splign:2.1.0"
     CDS             180..2138
                     /gene="Zfp418"
                     /gene_synonym="A230102I05Rik; ZNF418"
                     /codon_start=1
                     /product="zinc finger protein 418"
                     /protein_id="NP_666291.2"
                     /db_xref="CCDS:CCDS39756.1"
                     /db_xref="GeneID:232854"
                     /db_xref="MGI:MGI:2444763"
                     /translation="MAALKHLAQVPRSTEKGMVCIQGCVTFEDVAVYFSQEEWELLDE
                     SQRLLYLDVMLENFTLITSLAHWSEAEAEDKTCAPQIRTAKEGLPTKKPHPSDICSTV
                     LKDILHLSDLPGQKPHLTEVCTDLLDQKHHRAKNWLKKDVDSLVKNCIFHVAGNPSVC
                     SKIGEKFPAVWNLLQPKAIPKGEKQNQIKCRKAFHSEKNNSKSDKYNKSSSPQHRLHE
                     YPRLCSGKEGFESNSCEQDLNKYSIAPSQTDQTENRPYGCHDCGKWFGQKATLRIHQR
                     RHTGEKPYRCGECGKSFCQSSNLSEHCRVHSGERPFECLECGKAFGCHSSLLRHQRTH
                     TGEWPYECGDCGRLFRQIVSLITHQRTHTTEKPYECGQCEKSFSHKATLTVHQRVHTG
                     EKPYHCEACGKSFSQSANLIKHSKIHTGEKPYKCGECGLCFRQRATLMKHQRTHTSER
                     PYECRECGKFFKQYFYLIEHSRIHTTTEFYECGQCGKSYTQNATLIRHQRVHTGESPY
                     KCKECGKAFEYKSRLNRHQRTHTGERPYECAKCGKFFRESYNLAEHQKIHTKAKPYNC
                     DQCGKCFSRRADLVKHQRVHTGERPYTCGECGKTFSRTTNLVQHRRIHTGERPYECDQ
                     CGKSFSQVSTLTRHQLLHTGEKSYKCSK"
     exon            207..245
                     /gene="Zfp418"
                     /gene_synonym="A230102I05Rik; ZNF418"
                     /inference="alignment:Splign:2.1.0"
     exon            246..372
                     /gene="Zfp418"
                     /gene_synonym="A230102I05Rik; ZNF418"
                     /inference="alignment:Splign:2.1.0"
     exon            373..2700
                     /gene="Zfp418"
                     /gene_synonym="A230102I05Rik; ZNF418"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgcattttgt cctgtctttg gtttaactgt ccatgggttg gtatttggag gattctgagc
       61 tttaaaatca gcaagttaga ctaaaggtac gagagcgaac aggcactggg tgtcggccaa
      121 gcagaccatc atcagccgcg gcggccgtgc accggcccct gcgtactcta cagagccgga
      181 tggcggcgct gaagcacctg gctcaggttc ccagatctac agaaaagggt atggtctgta
      241 tacagggctg tgtaaccttt gaggacgtgg cagtttactt ctcccaggaa gagtgggagc
      301 tcctggatga atctcagagg ctcctgtatc ttgatgtgat gctggagaat tttaccctta
      361 taacctcact ggctcattgg tctgaagcag aggctgaaga caaaacctgt gcaccacaga
      421 tcaggactgc aaaggaaggt ctacccacga agaagcccca tccctctgac atctgtagca
      481 ccgtccttaa agatatcttg catctaagtg acctacccgg gcagaaacca catttgactg
      541 aggtgtgtac agacctcctg gaccagaagc atcacagagc caagaattgg ttaaagaaag
      601 atgtggactc ccttgtgaag aactgtatat tccatgtagc agggaaccct tctgtctgta
      661 gtaagattgg cgagaaattc ccagctgtat ggaatcttct ccaacccaag gccattccca
      721 aaggtgagaa acaaaatcaa attaagtgta gaaaggcttt tcactcagag aaaaataact
      781 ctaagtcaga taaatataac aaatcttcca gcccccaaca caggcttcat gaatatccaa
      841 gactttgcag tggaaaggag gggtttgagt ctaacagttg tgagcaagac ttaaacaagt
      901 actcgattgc accatcccag acagatcaga ctgaaaaccg accatatggg tgtcatgact
      961 gtggaaaatg gtttggccag aaagccacac ttagaataca ccagagacgc cataccggag
     1021 aaaaaccgta tagatgtggt gaatgtggaa agtctttttg tcaaagctct aacctaagcg
     1081 aacactgtag agttcatagt ggagaaagac cttttgagtg tctggaatgt gggaaagcct
     1141 tcgggtgcca ttctagtctt ctgcgacatc agagaacaca cacaggagaa tggccatatg
     1201 aatgtggtga ctgcgggagg ctgtttaggc agattgtcag cctgattaca caccagagga
     1261 ctcacactac agagaagcct tacgaatgtg gacagtgtga aaagtctttt agtcacaaag
     1321 ccacgcttac tgtacatcag agagttcaca ctggagagaa gccctatcac tgtgaagcat
     1381 gtgggaaatc cttcagccaa agcgccaacc ttattaaaca ctccaaaatt cacactggag
     1441 aaaagcctta taagtgtggg gaatgtggtc tatgctttcg ccagagagct accctcatga
     1501 aacaccagag aacccacacc tcagaaaggc cttatgaatg tagagaatgt ggtaagttct
     1561 ttaaacagta cttctacctc attgaacaca gtaggattca caccacaaca gaattttatg
     1621 agtgtggaca gtgcgggaaa tcttataccc aaaacgccac cctcatcaga caccagcgag
     1681 tccatacagg agagagtcct tataagtgta aggagtgtgg aaaagccttt gaatacaaat
     1741 ccagacttaa tcgacatcaa agaactcaca ctggtgaaag gccttatgag tgtgccaagt
     1801 gtgggaaatt cttcagggaa agctacaatc ttgctgaaca ccagaaaatt cacacgaaag
     1861 caaagcctta caattgtgat cagtgtggga agtgttttag ccggagagct gacttggtta
     1921 aacaccagag agttcacact ggtgaaaggc cttatacatg tggtgaatgt gggaagacct
     1981 tcagccgaac taccaacctt gttcaacaca gaagaattca cactggggaa cggccatacg
     2041 agtgtgacca gtgtgggaag tcttttagcc aggtgtctac cctcactagg catcagctac
     2101 ttcacactgg agaaaaatct tataaatgta gcaaatgaag gaaagcctag acaactctct
     2161 agcatcttct aacaccaaaa gatagaccat cataattcct ggaagccaac ccttgaaagc
     2221 accctcaggc ctcgaaagat gttgcattgt ttttcactgt aacaaactag agagcctcat
     2281 agagttctag gccgtgtaac ttgtactaga gagctagtct gcatgttcta gacagtctgt
     2341 ttccattgcc agaattaaat agctgccata atgtctcata gaaactgtca ctcctctagc
     2401 accttgccct gagtgtatat ccccccaaca tgcccatatt ctccccttcc ctaatggaag
     2461 cttcaacttc ctgtgccttg caaatgacct tcatcccctt ttctcactga atatgtatgg
     2521 gtctgtattt tgtctaaacg aacctggtct gggattagat ggaggctcca tcaaggaata
     2581 tcttctcaag tctttgtctc acatgattca tgtggctgtt tacatgatag gaactagcca
     2641 gagacttcct gccatgttaa tatgcaataa taaaagacct tatggatttt ttttcccatg
//
