LOCUS       NM_001033341            7909 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus zinc finger protein 407 (Zfp407), mRNA.
ACCESSION   NM_001033341 XM_140518 XM_898010 XM_917053
VERSION     NM_001033341.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7909)
  AUTHORS   Charrier,A., Ockunzzi,J., Main,L., Ghanta,S.V. and Buchner,D.A.
  TITLE     Molecular regulation of PPARgamma/RXRalpha signaling by the novel
            cofactor ZFP407
  JOURNAL   PLoS One 19 (5), e0294003 (2024)
   PUBMED   38781157
  REMARK    GeneRIF: Molecular regulation of PPARgamma/RXRalpha signaling by
            the novel cofactor ZFP407.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7909)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 7909)
  AUTHORS   Charrier,A., Xu,X., Guan,B.J., Ngo,J., Wynshaw-Boris,A.,
            Hatzoglou,M. and Buchner,D.A.
  TITLE     Adipocyte-specific deletion of zinc finger protein 407 results in
            lipodystrophy and insulin resistance in mice
  JOURNAL   Mol Cell Endocrinol 521, 111109 (2021)
   PUBMED   33285243
  REMARK    GeneRIF: Adipocyte-specific deletion of zinc finger protein 407
            results in lipodystrophy and insulin resistance in mice.
REFERENCE   4  (bases 1 to 7909)
  AUTHORS   Charrier,A., Wang,L., Stephenson,E.J., Ghanta,S.V., Ko,C.W.,
            Croniger,C.M., Bridges,D. and Buchner,D.A.
  TITLE     Zinc finger protein 407 overexpression upregulates PPAR target gene
            expression and improves glucose homeostasis in mice
  JOURNAL   Am J Physiol Endocrinol Metab 311 (5), E869-E880 (2016)
   PUBMED   27624101
REFERENCE   5  (bases 1 to 7909)
  AUTHORS   Buchner,D.A., Charrier,A., Srinivasan,E., Wang,L., Paulsen,M.T.,
            Ljungman,M., Bridges,D. and Saltiel,A.R.
  TITLE     Zinc finger protein 407 (ZFP407) regulates insulin-stimulated
            glucose uptake and glucose transporter 4 (Glut4) mRNA
  JOURNAL   J Biol Chem 290 (10), 6376-6386 (2015)
   PUBMED   25596527
  REMARK    GeneRIF: transcriptome analysis revealed that ZFP407 regulates many
            peroxisome proliferator-activated receptor (PPAR) gamma target
            genes beyond Glut4.
REFERENCE   6  (bases 1 to 7909)
  AUTHORS   Nakahara,M., Tateyama,H., Araki,M., Nakagata,N., Yamamura,K. and
            Araki,K.
  TITLE     Gene-trap mutagenesis using Mol/MSM-1 embryonic stem cells from
            MSM/Ms mice
  JOURNAL   Mamm Genome 24 (5-6), 228-239 (2013)
   PUBMED   23604909
REFERENCE   7  (bases 1 to 7909)
  AUTHORS   Taniwaki,T., Haruna,K., Nakamura,H., Sekimoto,T., Oike,Y.,
            Imaizumi,T., Saito,F., Muta,M., Soejima,Y., Utoh,A., Nakagata,N.,
            Araki,M., Yamamura,K. and Araki,K.
  TITLE     Characterization of an exchangeable gene trap using pU-17 carrying
            a stop codon-beta geo cassette
  JOURNAL   Dev Growth Differ 47 (3), 163-172 (2005)
   PUBMED   15840001
REFERENCE   8  (bases 1 to 7909)
  AUTHORS   Okazaki,N., F-Kikuno,R., Ohara,R., Inamoto,S., Koseki,H.,
            Hiraoka,S., Saga,Y., Seino,S., Nishimura,M., Kaisho,T., Hoshino,K.,
            Kitamura,H., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: IV. The complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (3), 205-218 (2004)
   PUBMED   15368895
REFERENCE   9  (bases 1 to 7909)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   10 (bases 1 to 7909)
  AUTHORS   Araki,K., Imaizumi,T., Sekimoto,T., Yoshinobu,K., Yoshimuta,J.,
            Akizuki,M., Miura,K., Araki,M. and Yamamura,K.
  TITLE     Exchangeable gene trap using the Cre/mutated lox system
  JOURNAL   Cell Mol Biol (Noisy-le-grand) 45 (5), 737-750 (1999)
   PUBMED   10512203
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC124187.3, AC149591.5, AC126021.3 and AC152060.3.
            
            On Aug 20, 2009 this sequence version replaced NM_001033341.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660821.67659.1,
                                           SRR10223969.18816.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-67                AC124187.3         134561-134627       c
            68-4787             AC124187.3         103450-108169       c
            4788-4902           AC124187.3         97993-98107         c
            4903-4977           AC149591.5         176058-176132       c
            4978-5144           AC126021.3         30186-30352
            5145-5228           AC126021.3         33894-33977
            5229-5349           AC126021.3         41811-41931
            5350-5528           AC126021.3         68893-69071
            5529-7909           AC152060.3         86364-88744
FEATURES             Location/Qualifiers
     source          1..7909
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 57.53 cM"
     gene            1..7909
                     /gene="Zfp407"
                     /gene_synonym="6430585N13Rik; Gm333; Gm334; Gm948; ZNF407"
                     /note="zinc finger protein 407"
                     /db_xref="GeneID:240476"
                     /db_xref="MGI:MGI:2685179"
     exon            1..67
                     /gene="Zfp407"
                     /gene_synonym="6430585N13Rik; Gm333; Gm334; Gm948; ZNF407"
                     /inference="alignment:Splign:2.1.0"
     exon            68..4787
                     /gene="Zfp407"
                     /gene_synonym="6430585N13Rik; Gm333; Gm334; Gm948; ZNF407"
                     /inference="alignment:Splign:2.1.0"
     CDS             128..6868
                     /gene="Zfp407"
                     /gene_synonym="6430585N13Rik; Gm333; Gm334; Gm948; ZNF407"
                     /codon_start=1
                     /product="zinc finger protein 407"
                     /protein_id="NP_001028513.2"
                     /db_xref="CCDS:CCDS50338.1"
                     /db_xref="GeneID:240476"
                     /db_xref="MGI:MGI:2685179"
                     /translation="MDSENKHDNDEDESVKGAKDPRSVSSRDDSSEPVSDDMANVSEN
                     FTSKRVFSESSNSDGVAAEEYRSERASKRLRTEALEPETREQGACGLGTVEANVHLAE
                     MGKEAFPANCSEGGSALPSVFSPSCDFSTSNILPLKVDEVKKPAREMVSLVPERHNPF
                     PPEERSISCSFGSVETGLRCGVCGCSFSSCSALEKHVECHVEEGKERTCCHCSHRAES
                     SSSPHEHVRHTHGPQKVFSCDLCGFQCAEENLLNAHYLGKTHLRRQNLAARGGFVQIL
                     TKPSFPKKACVMGTKNVRTKPRASKPIAKTGDSRVVPSTGNDFKDCRGAPSEDSAGGS
                     ELLVEMVPSRKISSGKAHVVEENVSFGVAQNPENQNKQLGGLVSSEGLLNKPESTKNA
                     LQMAHVSISTTSRPRSERNLLVLGNSFRRRSGTFTLKGQAKKRFNLLGINKRGTNETQ
                     RMYMKHFRTQMKTNAQPVLEQVEMSKDVQSLCVTTSDNPEVMQDKTAFCLSGSTRLGS
                     LPVKPADHQLSVQCTCTECGQIAANKTDFEVHVKQCHGREMQFHCQTCDFSSPSRRDL
                     EEHVHSNQHQHMTPVLSCQCCSFISLNETGLRDHMKEKHGMGFFCTSCNLFLSEKDVE
                     EHRATESHNSLVVQPKTASSLSGDSVLPFSTVESENPADSREDSGKAAQEGPAESRAS
                     HGTEARHSSKPQFQCKKCFYKTRSSTVLTRHIKLRHGQDYHFLCKACNLYSLSKEGME
                     KHIKRSKHLENAKKNNIGLSFEECIERVCIGANDKKEESSVSGSGRPEGHVGVQSQEH
                     SQREQSMLTPKELPQSGVITKEDELGLATTPKRGRPKGSISRTCSHCGLLASSITNLT
                     VHIRRKHSHQYSYLCKVCKYYTVTKGDMERHCATKKHKGRVEIEANGKQSSDIVVGPE
                     GGNLEACKDSTSLAVTVSDAQASKPAKSDTRTLETPGVGIGNAGDAEAGSVFPSGDGE
                     LSSQLSDKKGQLSLETEDLLQLDDACSQREVAGSSDNKCLQCEFSAHSAASLELHVKR
                     KHTKEFQFYCMACDYYAVTRREMTRHAATEKHRMKRQSYLSASSVEAGSSEISKNITI
                     PEEEHSHNSEEFQIHPHQSSGTLQCRNPADCSILDDNTNLGMSKVLCAPDSVTVVTEQ
                     ESNFSEGHSFCETLQQPLVKDKSMKPREIVSPNTPSNLSLPGCLQSENLASSAVDCET
                     AKKNRDVLDAVGDRSTPCEDEGGSVDDSEEKILDKSPCPGDPDGGHSAESTSSVVMKI
                     PREQLDLDGGGQNKVGCEQTSEDLKDVQANPILENKEILINSQEEAEVILEEDAPTSN
                     GTADSNDVYETIISIDDKGQTMYSFGRFDSSIIRIKTEDGELVEQPEEGLTATGGRVS
                     ELPLKDCAQGLKKKKVEGGSFGESTRIRCDDCGFLADGLSGLNVHIAMKHPTKEKHFH
                     CLLCGKSFYTESNLHQHLASAGHMRNEQASVEELPEGGATFKCVKCTEPFDSEQNLFL
                     HIKGQHEELLREVNKYIVEDTEQINREREENQGNVCKYCGKMCRSSNSMAFLAHIRTH
                     TGSKPFKCKICHFATAQLGDARNHVKRHLGMREYKCHVCGVAFVMKKHLNTHLLGKHG
                     VGTPKERKFTCHLCDRSFTEKWALNNHMKLHTGEKPFKCTWPTCHYSFLTASAMKDHY
                     RTHTGEKSFLCDLCGFAGGTRHALTKHRRQHTGEKPFKCDECNFASTTQSHLTRHKRV
                     HTGEKPYRCPWCDYRSNCAENIRKHILHTGKHEGVKMYNCPKCDYGTNVPVEFRNHLK
                     EQHPDIENPDLAYLHAGIVSKSYECRLKGQGATFVETDSPFTAATLAEESPVKERSLR
                     SSKRQAASPEQVQQVIIIQGYDGEFALDASVEETAAATLQTLAMAGQVARVVHITEHG
                     QVIATSQNGSHVGSVVPGPILPEQLADGTTQVVVMGGSMESHSVDEALSPGAAVIQQV
                     TKQEVLSLSEAGVPPSDNSSALDALLCAVTELGEVEGRVGHEEKGRPSHKDVLIQLPS
                     QEAAQAHAKAEATEAQLFQDVEESPASMEVLTQVVRPSTIITSQERAQVAFKKMVQGV
                     LQFAVCDTAAASQLIKDGVTQVIVNEEGAVHMVAGEGSQFIMQEAETHGLRVPAEHMD
                     LVESEGEISQIIVTEELVQAMVRESNSSFPEGATHYIVTELPPGVQEDTGVYSHTVIE
                     TASSPEILQAGAALSAEAVGSSSTEQLTSMVIYTQDGSPAATVIQSQRENSELQEA"
     exon            4788..4902
                     /gene="Zfp407"
                     /gene_synonym="6430585N13Rik; Gm333; Gm334; Gm948; ZNF407"
                     /inference="alignment:Splign:2.1.0"
     exon            4903..4977
                     /gene="Zfp407"
                     /gene_synonym="6430585N13Rik; Gm333; Gm334; Gm948; ZNF407"
                     /inference="alignment:Splign:2.1.0"
     exon            4978..5144
                     /gene="Zfp407"
                     /gene_synonym="6430585N13Rik; Gm333; Gm334; Gm948; ZNF407"
                     /inference="alignment:Splign:2.1.0"
     exon            5145..5228
                     /gene="Zfp407"
                     /gene_synonym="6430585N13Rik; Gm333; Gm334; Gm948; ZNF407"
                     /inference="alignment:Splign:2.1.0"
     exon            5229..5349
                     /gene="Zfp407"
                     /gene_synonym="6430585N13Rik; Gm333; Gm334; Gm948; ZNF407"
                     /inference="alignment:Splign:2.1.0"
     exon            5350..5528
                     /gene="Zfp407"
                     /gene_synonym="6430585N13Rik; Gm333; Gm334; Gm948; ZNF407"
                     /inference="alignment:Splign:2.1.0"
     exon            5529..7909
                     /gene="Zfp407"
                     /gene_synonym="6430585N13Rik; Gm333; Gm334; Gm948; ZNF407"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7885..7890
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp407"
                     /gene_synonym="6430585N13Rik; Gm333; Gm334; Gm948; ZNF407"
                     /note="hexamer: AATAAA"
     regulatory      7891..7896
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp407"
                     /gene_synonym="6430585N13Rik; Gm333; Gm334; Gm948; ZNF407"
                     /note="hexamer: ATTATA"
     polyA_site      7904
                     /gene="Zfp407"
                     /gene_synonym="6430585N13Rik; Gm333; Gm334; Gm948; ZNF407"
                     /note="major polyA site"
     polyA_site      7909
                     /gene="Zfp407"
                     /gene_synonym="6430585N13Rik; Gm333; Gm334; Gm948; ZNF407"
                     /note="major polyA site"
ORIGIN      
        1 gagggaagac ggtgagccgg aggagtcagt cagagggccg agcaggagcg atttccccga
       61 caaacaggtt gtaaactcca gttaaatcca actctaacga cgaaacatca tcagaacttt
      121 attgagaatg gattctgaga ataaacatga caatgatgag gatgaaagtg ttaagggagc
      181 aaaagatccg aggagtgttt catcccgcga tgacagttct gagcctgtat ctgatgacat
      241 ggcaaatgtc tctgagaatt ttacgagcaa aagagttttt tccgagtcgt ccaactcgga
      301 cggtgttgct gcggaggaat acagaagtga gcgtgcttcc aagcgactga gaacagaggc
      361 actggagcct gagacaagag agcagggtgc ctgtgggttg ggcactgtgg aagctaatgt
      421 ccatttggct gaaatgggaa aggaggcctt tccagcaaac tgctcagaag gaggcagcgc
      481 tcttcccagt gttttctccc catcttgtga ttttagcaca tctaatattc ttcctctgaa
      541 agtagatgaa gtgaaaaagc ctgctcggga aatggtttcc cttgttcctg aaagacacaa
      601 tccttttcct ccagaagaaa ggagcattag ttgtagcttt ggaagtgtag agacaggact
      661 caggtgcggc gtgtgtggct gttcattttc ctcttgctct gctttggaaa agcatgtgga
      721 gtgtcatgtg gaagagggga aggaacggac ctgctgccac tgtagccaca gagcagagag
      781 cagctcatct cctcatgagc atgtcagaca tactcatggg ccgcagaaag tcttttcctg
      841 tgatctctgt ggcttccaat gtgcagaaga aaacctgttg aatgcacatt atcttggcaa
      901 aacacacctt cgtcgtcaga accttgctgc tcgtggagga ttcgtacaga tcttaacaaa
      961 accatctttt cctaaaaaag cctgtgtcat gggaacaaaa aatgttagaa caaaaccaag
     1021 agcttctaaa ccaatagcaa agactgggga ttcaagagta gtgccgagta ctgggaatga
     1081 ctttaaagac tgcagaggag ccccttctga agacagtgct ggtggtagtg agctccttgt
     1141 tgaaatggtg ccatctagga aaatctcatc aggcaaagca catgtagttg aggaaaatgt
     1201 tagttttggt gtagctcaaa atcctgaaaa tcagaacaaa cagctagggg gcttagtaag
     1261 ctcagagggt cttttaaata aaccagaatc cactaaaaat gccctacaga tggcgcatgt
     1321 cagtatcagt accacctcaa ggccaagatc tgagcgaaac ctcctagtgt tgggtaatag
     1381 ctttcgcaga cgaagtggca cttttacttt aaagggccag gcaaagaaaa ggtttaatct
     1441 tctaggaatt aataaaaggg gtacaaatga aactcagagg atgtatatga aacactttag
     1501 aacacagatg aaaacaaacg cacagccagt gctggaacaa gtagagatga gcaaagatgt
     1561 tcaaagtctg tgtgtgacta cctcagacaa cccagaagtg atgcaggaca agacagcctt
     1621 ctgtctttca ggctccacac ggctgggctc cctgccagta aagccagctg accaccagct
     1681 ctctgtgcag tgcacttgta cagagtgtgg ccagatagct gcaaataaga cagacttcga
     1741 agttcacgtt aaacagtgcc atggaagaga gatgcagttt cattgtcaga cttgtgactt
     1801 ttctagtccg tcaaggagag acttggagga gcacgtgcac agtaatcagc atcagcacat
     1861 gacacctgtc ctcagctgtc agtgttgttc ctttatttcc ttgaatgaaa caggtcttag
     1921 agaccatatg aaggagaagc atggcatggg ctttttctgc acctcttgta atctgttctt
     1981 gtctgagaaa gatgtggaag aacacagagc aaccgagtca cataatagtt tagtggttca
     2041 accaaagacg gcttcatcat tgagtggtga ttctgttcta cctttcagta ctgtagaatc
     2101 agaaaacccg gccgattcta gagaagactc agggaaggcc gcgcaggaag gacctgctga
     2161 gtccagggca agccatggaa ctgaagcacg gcattcaagt aagccgcagt ttcagtgtaa
     2221 gaagtgtttt tataaaacga ggtcctccac tgttctcacg agacacataa agcttcgaca
     2281 tggacaggac tatcattttc tctgtaaagc atgcaatctt tattctttga gcaaagaagg
     2341 aatggagaag cacattaaaa gaagcaaaca tcttgaaaat gctaagaaaa acaatattgg
     2401 tttaagtttt gaagagtgca ttgaaagagt atgtataggt gcaaatgata aaaaagaaga
     2461 gtccagtgtt tctggaagtg gaaggcccga aggccatgtt ggtgtgcaat cacaggagca
     2521 ttcccaacgt gaacagagta tgctaacacc caaggagctt ccacagtctg gtgtcatcac
     2581 caaagaggat gaattaggct tagccactac tccaaagaga gggaggccca aaggcagcat
     2641 ttctcggact tgttcacact gtggactttt ggcctctagt attacaaatt tgactgtgca
     2701 catcaggcgt aaacacagtc accagtatag ttacttgtgc aaagtatgta agtattatac
     2761 tgtaactaaa ggagatatgg aacgtcattg tgccaccaag aaacataaag gacgggtaga
     2821 aatagaagca aatgggaaac aaagttcaga catagttgtt ggcccagaag gtggtaatct
     2881 tgaagcatgt aaggatagca cctctctagc agtgaccgtt tctgacgcac aggctagcaa
     2941 gccggctaag tcagacacac gcactttaga aacgccggga gtgggcattg gaaatgcagg
     3001 tgatgctgaa gctgggagtg tatttccttc tggagatgga gagcttagca gtcaactctc
     3061 tgataaaaag ggacagctat ctctagagac agaggacctg ctacagcttg atgatgcatg
     3121 ctctcagaga gaggttgcag gttcaagtga caataagtgt cttcagtgtg agttcagtgc
     3181 tcactctgcc gcttcactcg agctgcatgt gaaaaggaag cacaccaaag agttccagtt
     3241 ttactgtatg gcctgtgatt actatgcggt gactcgcaga gagatgacga ggcatgctgc
     3301 aacagagaag catagaatga aaaggcagtc ttacctcagc gcttctagtg tggaagcagg
     3361 ttcttcagaa atatccaaga acatcactat acccgaggag gagcattcac acaattctga
     3421 ggaatttcaa atacatccac accagtcatc tggtactctc caatgtagaa atcctgcaga
     3481 ttgttctatt ttagatgata ataccaattt gggtatgtct aaagtactct gtgctcctga
     3541 ttcagtgaca gttgtgactg agcaagaatc taattttagt gaaggtcact ccttttgtga
     3601 gaccttacag cagccccttg ttaaggacaa aagtatgaaa cccagggaga tagtgtcccc
     3661 taacactccc tctaacctca gcctcccagg ctgtcttcag agtgaaaacc tagcgagctc
     3721 tgctgtggac tgtgagacag caaagaaaaa ccgtgatgtg ttggatgctg ttggggatag
     3781 aagtacaccc tgtgaagatg agggaggcag tgtggatgat agtgaagaaa aaattcttga
     3841 caagtccccc tgccctggag acccagatgg gggccattct gccgaatcta cttcctctgt
     3901 ggtaatgaaa ataccaagag aacaactgga cctggatggc ggtggccaga acaaggttgg
     3961 atgtgagcag acttctgaag atttaaaaga tgtgcaagca aatcctattc ttgagaataa
     4021 ggaaattctg ataaattcac aagaagaagc tgaagtcatt ttggaagagg atgccccaac
     4081 ctcgaatggc acagctgaca gtaatgatgt ttatgagact ataataagta ttgatgacaa
     4141 agggcaaaca atgtacagtt ttggcaggtt tgattcgtcc ataattagaa taaaaactga
     4201 agatggtgaa ttggtagaac agccagaaga gggtctgacg gcgacaggag ggagagttag
     4261 tgagttgccc ctgaaagact gtgctcaggg gttgaagaag aagaaagttg aaggtggttc
     4321 ttttggtgag tccacacgaa tccggtgtga tgattgtggt ttcttagcag atggactgag
     4381 tggcctgaat gttcatatag ccatgaagca tcctacaaaa gagaagcact ttcattgttt
     4441 actatgtgga aaatccttct atactgagag caaccttcac cagcatttgg ctagtgctgg
     4501 tcacatgaga aatgaacagg ccagtgtaga agagcttcca gaaggagggg ccaccttcaa
     4561 atgtgtcaag tgtacagagc cctttgattc ggaacagaat ttatttctgc atattaaagg
     4621 acagcatgag gagttgctgc gggaggtaaa caagtacata gtggaagaca ccgagcagat
     4681 caatcgggag agagaggaga accagggcaa cgtctgcaag tattgtggga agatgtgtcg
     4741 gagtagcaac tccatggcct ttctggctca cattcggact cacacaggat caaaaccatt
     4801 caagtgcaag atatgccatt ttgcaacagc tcagcttgga gatgccagaa accatgtgaa
     4861 aaggcacctt gggatgaggg agtacaagtg tcacgtctgt ggggttgctt ttgtgatgaa
     4921 gaaacactta aatactcacc tgctaggcaa gcacggagtt ggcaccccaa aggaaaggaa
     4981 atttacatgc cacttatgtg atagaagttt cacggagaaa tgggccttga acaaccacat
     5041 gaaactgcac acgggagaaa agccttttaa gtgcacctgg cccacgtgcc actactcatt
     5101 cctcacagca tcagcgatga aagaccacta caggacgcac acaggcgaga agtcgtttct
     5161 ctgtgacctc tgtggcttcg ccggtgggac ccggcatgcc ctcaccaagc accgtcggca
     5221 gcatacaggg gaaaagcctt tcaaatgtga tgagtgtaac ttcgcctcca caacccagtc
     5281 acacttgact cgtcataagc gtgtgcacac tggagagaag ccatacaggt gcccttggtg
     5341 tgactacagg tcaaattgtg ctgagaatat ccgcaaacac attttacaca ccggcaaaca
     5401 tgaaggtgtc aagatgtaca actgcccaaa atgcgactat gggacgaatg tccccgtgga
     5461 gttccgaaac cacctgaaag agcagcaccc cgacattgag aaccctgacc tcgcgtactt
     5521 gcatgctggc atcgtgtcca agtcctatga gtgccgcctg aaaggacaag gagccacgtt
     5581 tgtggagaca gacagcccct tcactgcagc caccctggcg gaggagtcgc ctgtcaagga
     5641 gaggtccttg aggagcagca agcggcaggc tgcgtcccct gagcaggtcc agcaggtcat
     5701 catcatccag ggctacgatg gcgagttcgc cctggacgcc tccgtggaag agactgctgc
     5761 ggccacactg cagacgctgg cgatggctgg ccaagtggcc agggtggtgc acatcacaga
     5821 acatgggcag gtcattgcca caagtcagaa cgggtcgcat gtgggcagtg tggtacctgg
     5881 acccatcctc cctgagcagt tggcagacgg aaccacccag gtggttgtca tggggggttc
     5941 catggaaagt cacagtgtgg acgaggccct cagcccaggt gctgctgtca tacagcaggt
     6001 caccaagcag gaggtcttaa gtctctctga ggctggagtc cctccatctg acaactcctc
     6061 agccttagat gcactgctgt gtgctgtcac tgagttggga gaggtggagg gcagagtggg
     6121 gcatgaggaa aaaggtcggc ccagccacaa ggacgtgctg atccagctgc ccagccagga
     6181 agcggcccag gctcacgcca aggcggaggc cacggaggct cagctgttcc aagatgttga
     6241 ggagagtcca gcatccatgg aagtactgac ccaggttgtc cgcccctcaa ccatcatcac
     6301 gtctcaggaa cgagcccagg tggccttcaa gaagatggtt cagggagtcc tgcagtttgc
     6361 tgtctgtgac acggctgcag ctagccagct gataaaggat ggcgttactc aagtcattgt
     6421 gaatgaagag ggcgctgtcc acatggtggc cggagaaggc tcccagttca tcatgcagga
     6481 ggctgagacc catggcctgc gggtgccagc cgagcacatg gacctggtag agtcagaagg
     6541 agagatctct cagatcattg taacagaaga gctagtccaa gccatggtcc gtgagtccaa
     6601 cagcagcttc cccgagggcg ccactcacta cattgtgacc gagttgcctc cgggtgtaca
     6661 ggaggacaca ggagtttact cccacactgt gatagagaca gccagctctc cagagattct
     6721 gcaggctggg gctgcactca gtgctgaggc tgtgggttcc agcagcacgg aacagttgac
     6781 gagcatggtc atctataccc aggatggctc cccagcagcc acagtgatcc agagccaaag
     6841 agaaaacagt gagctccaag aagcgtgagg caggcctcca tgctgggcac cgggcaggct
     6901 gcggagatct acctgtgcca ccctgaggcc acggaacttt gtcgtgttta cttgagaggt
     6961 gtgctgaaca agcccttcag gcaagggtaa catcggccac taaggaggca cccgaggagg
     7021 gcagcaagcc aagcctacac ctcggttgcc cagcagcctc ctgagagtgg gcaggccgga
     7081 tgaacctgtg ccatagagca ctgggccctc tgcgggtggc cttgcccctc gagtaccatt
     7141 gtggggagca gcagttttcg ctgggtcttc tcccatataa gttccctgtt tagtcatcaa
     7201 aagatggtgc cccctatggg aaataggcga cgtcgctagc ctcagccctc tgtgcctgct
     7261 acggcgcaca cagctctgcc atctcctccc acagccgatt aaaaatcaga actaccaaga
     7321 ttacatcttg aagcagtgaa cacattacat tgtttttatt gttattttaa gtttaagata
     7381 atggtgttcc cagaccaaag gaagcctgtt agttcatttt atgtataaat ttcctctctg
     7441 caaatatttt aggggattcc ttcgccgtgg tcgttgagta atctttcaac tgtggtttga
     7501 gaaaagtctt gaaagtttta ttcagttaca atccacctgg gttgagacaa ttaattaatt
     7561 ctgaattcat ttcataccat aaaattcatt ttgtttgtac atgaaatgtc cactatgaaa
     7621 atatcattca ttgctttttc tatgaaatat ttgtttgtct cagtatcatt tctgcaggat
     7681 ttatctgtga ctttcagaat atggggaggc tgacattgac cgttacagtg gacgcccccc
     7741 gttgccctcg tcccccagca ctgtaagtgc agggtgcagg gtctgatgat ctttcttgat
     7801 tccattgctc tttttgtttt gttctcaaca ttgtaaaata gccccattcc tcaaaggcaa
     7861 aattgttctt gttgttttct ttgaaataaa attatagcat taaactaaa
//
