LOCUS       NM_001357697            4197 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus zinc finger protein 40 (Zfp40), transcript variant 2,
            mRNA.
ACCESSION   NM_001357697 XM_017317454
VERSION     NM_001357697.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4197)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4197)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   3  (bases 1 to 4197)
  AUTHORS   Wiese,C.B., Ireland,S., Fleming,N.L., Yu,J., Valerius,M.T.,
            Georgas,K., Chiu,H.S., Brennan,J., Armstrong,J., Little,M.H.,
            McMahon,A.P. and Southard-Smith,E.M.
  TITLE     A genome-wide screen to identify transcription factors expressed in
            pelvic Ganglia of the lower urinary tract
  JOURNAL   Front Neurosci 6, 130 (2012)
   PUBMED   22988430
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 4197)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   5  (bases 1 to 4197)
  AUTHORS   Shannon,M. and Stubbs,L.
  TITLE     Molecular characterization of Zfp54, a zinc-finger-containing gene
            that is deleted in the embryonic lethal mutation tw18
  JOURNAL   Mamm Genome 10 (7), 739-743 (1999)
   PUBMED   10384051
REFERENCE   6  (bases 1 to 4197)
  AUTHORS   Grisel,J.E., Belknap,J.K., O'Toole,L.A., Helms,M.L., Wenger,C.D.
            and Crabbe,J.C.
  TITLE     Quantitative trait loci affecting methamphetamine responses in BXD
            recombinant inbred mouse strains
  JOURNAL   J Neurosci 17 (2), 745-754 (1997)
   PUBMED   8987796
REFERENCE   7  (bases 1 to 4197)
  AUTHORS   Barclay,J., King,T.F., Crossley,P.H., Barnard,R.C., Larin,Z.,
            Lehrach,H. and Little,P.F.
  TITLE     Physical analysis of the region deleted in the tw18 allele of the
            mouse tcl-4 complementation group
  JOURNAL   Genomics 36 (1), 39-46 (1996)
   PUBMED   8812414
REFERENCE   8  (bases 1 to 4197)
  AUTHORS   Stubbs,L., Carver,E.A., Shannon,M.E., Kim,J., Geisler,J.,
            Generoso,E.E., Stanford,B.G., Dunn,W.C., Mohrenweiser,H.,
            Zimmermann,W., Watt,S.M. and Ashworth,L.K.
  TITLE     Detailed comparative map of human chromosome 19q and related
            regions of the mouse genome
  JOURNAL   Genomics 35 (3), 499-508 (1996)
   PUBMED   8812484
REFERENCE   9  (bases 1 to 4197)
  AUTHORS   Noce,T., Fujiwara,Y., Ito,M., Takeuchi,T., Hashimoto,N.,
            Yamanouchi,M., Higashinakagawa,T. and Fujimoto,H.
  TITLE     A novel murine zinc finger gene mapped within the tw18 deletion
            region expresses in germ cells and embryonic nervous system
  JOURNAL   Dev Biol 155 (2), 409-422 (1993)
   PUBMED   8432396
REFERENCE   10 (bases 1 to 4197)
  AUTHORS   Noce,T., Fujiwara,Y., Sezaki,M., Fujimoto,H. and Higashinakagawa,T.
  TITLE     Expression of a mouse zinc finger protein gene in both
            spermatocytes and oocytes during meiosis
  JOURNAL   Dev Biol 153 (2), 356-367 (1992)
   PUBMED   1397691
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CT030648.7, AC151285.3 and BC065097.1.
            
            On Nov 4, 2017 this sequence version replaced XM_017317454.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR6116558.170115.1,
                                           SRR1660821.14038.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164138, SAMN01164139
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-178               CT030648.7         61350-61527         c
            179-304             CT030648.7         59952-60077         c
            305-468             CT030648.7         59620-59783         c
            469-553             AC151285.3         6345-6429
            554-680             AC151285.3         10176-10302
            681-3487            AC151285.3         11213-14019
            3488-4197           BC065097.1         3384-4093
FEATURES             Location/Qualifiers
     source          1..4197
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 11.56 cM"
     gene            1..4197
                     /gene="Zfp40"
                     /gene_synonym="CTfin12; NTfin12; Zfp-40"
                     /note="zinc finger protein 40"
                     /db_xref="GeneID:22700"
                     /db_xref="MGI:MGI:99185"
     exon            1..178
                     /gene="Zfp40"
                     /gene_synonym="CTfin12; NTfin12; Zfp-40"
                     /inference="alignment:Splign:2.1.0"
     exon            179..304
                     /gene="Zfp40"
                     /gene_synonym="CTfin12; NTfin12; Zfp-40"
                     /inference="alignment:Splign:2.1.0"
     exon            305..468
                     /gene="Zfp40"
                     /gene_synonym="CTfin12; NTfin12; Zfp-40"
                     /inference="alignment:Splign:2.1.0"
     CDS             434..2824
                     /gene="Zfp40"
                     /gene_synonym="CTfin12; NTfin12; Zfp-40"
                     /note="isoform 1 is encoded by transcript variant 2"
                     /codon_start=1
                     /product="zinc finger protein 40 isoform 1"
                     /protein_id="NP_001344626.1"
                     /db_xref="CCDS:CCDS37473.1"
                     /db_xref="GeneID:22700"
                     /db_xref="MGI:MGI:99185"
                     /translation="MVKRGNCSKGSRRVPVFVPETETQKGATGKMAASLIDVPQDLLT
                     FRNVAVDFSKEEWEYLNSSQRALYMDVMWENYSNLVFVENHCICGKYEEDMDQSSNHI
                     IYQHANIEEKSYKYHELDKMLYESSQSTPYNTSDTTENCKMYGSDNQWDPSNESLNLK
                     AHKSRSTEEEEYKDYREYLNLCSIIGSYTQMDTRKKEHKITEHDKFFDSKHKLMIKRM
                     CSGEKPYQCRKCGKCFRTYSSLYRHRRTHPGEKPYKLTECNKSILYLSHHKVHYNIHY
                     GEKPYKCIECGKCYYHSSFEKHYRIHSEEESYKCNDCRKSFICCLGLKRHHKIHGGER
                     PYECKQCSKSFYTSSHLENHYRTHRRKLHRCNECGKSLSSSSGLQRHQRIHRGEKAYI
                     CAECNKCFIQKSQLKTHQRIHTGEKSYKCSECEKSFTVGSSLRIHQRIHTGEKPYKCS
                     ECHKCFIQQAHLRRHQKIHTGEKPYKCSECEKSFTVGSDLRMHQKIHTGEKPYKCSDC
                     DKCFIQKAKLKKHQRIHTGEKPYKCSECEKCFTVVSDLRTHQKIHTGEKPYKCSECDK
                     CFIRKANLRRHHRIHTGEKPYKCSDCGKCFIQKANLRTHERIHTGEKPYKCECGKSFT
                     VGSDLRKHQKCHTGEKPYKCSECNKCFIRKAHLRRHQRIHTGEKPYKCSDCGKCFIQK
                     ANLRTHQKIHTGEKPYKCSECDKCFIQKDHLRTHQRLHTGEKPYKCSECEKSFTGGSV
                     LRKHQKIHTARSLTNAMNLTNPLSKKPTLELIKEFIQESSLLNAMYIAQSLPASHV"
     exon            469..553
                     /gene="Zfp40"
                     /gene_synonym="CTfin12; NTfin12; Zfp-40"
                     /inference="alignment:Splign:2.1.0"
     exon            554..680
                     /gene="Zfp40"
                     /gene_synonym="CTfin12; NTfin12; Zfp-40"
                     /inference="alignment:Splign:2.1.0"
     exon            681..4176
                     /gene="Zfp40"
                     /gene_synonym="CTfin12; NTfin12; Zfp-40"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3490..3495
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp40"
                     /gene_synonym="CTfin12; NTfin12; Zfp-40"
                     /note="hexamer: AATAAA"
     polyA_site      3514
                     /gene="Zfp40"
                     /gene_synonym="CTfin12; NTfin12; Zfp-40"
                     /note="major polyA site"
     regulatory      4130..4135
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp40"
                     /gene_synonym="CTfin12; NTfin12; Zfp-40"
                     /note="hexamer: AATAAA"
     regulatory      4153..4158
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp40"
                     /gene_synonym="CTfin12; NTfin12; Zfp-40"
                     /note="hexamer: AATAAA"
     polyA_site      4154
                     /gene="Zfp40"
                     /gene_synonym="CTfin12; NTfin12; Zfp-40"
     polyA_site      4176
                     /gene="Zfp40"
                     /gene_synonym="CTfin12; NTfin12; Zfp-40"
                     /note="major polyA site"
ORIGIN      
        1 attcactgag ggaccgggga agctgcgagg tccggaatcc ggggtggagg acacgggctt
       61 ctctaggagg gcgtgaaaat tccaggcatc cacaggtgcc gcgagaggag tcctgagaaa
      121 gtcattagtc aacagcgctg tagcttgagc ctcagcccgg cagccataga acgcccagga
      181 tctgttgatc ttcaaggctg tgaaggtgga cttggtgcag gaggaatgtg aaggcctaga
      241 ccttactcac ggggctttta cagagatctc cagttggaga agtatagcag tctggtttct
      301 ctaggtgtga gcatctttcc gttttctttc atgaaaagtt ccagttactc tctgaggaat
      361 atctttctcg catgcagatc tcacactcct cagccagtcc tgcttacctg tgaagcagag
      421 caaagagccc tggatggtga agagaggaaa ctgtagcaaa ggatccagaa gagttcccgt
      481 ctttgttcct gagacagaaa ctcagaaagg agcaacagga aaaatggctg cttctctgat
      541 agatgtgccc caggatctac tgacattcag aaatgtggct gtggacttct ccaaggagga
      601 atgggaatat ctcaactcct ctcaaagagc tctatacatg gatgtaatgt gggagaatta
      661 cagcaatcta gtctttgtag aaaaccattg catatgtggt aaatacgaag aggacatgga
      721 tcaaagttca aatcatatta tctatcaaca tgcaaatatt gaagagaagt cttacaaata
      781 tcatgagctt gacaaaatgc tttatgaatc ctcccaaagc acaccttata atacaagtga
      841 tactacagaa aactgcaaga tgtatgggag tgataaccaa tgggatccat ctaatgaatc
      901 attaaaccta aaggcacata aaagtaggag cactgaggaa gaagaataca aagattatag
      961 ggagtattta aatttgtgtt ccatcattgg ctcatataca caaatggaca ctagaaagaa
     1021 agaacacaaa attacagagc atgataaatt ttttgactct aaacataaac tcatgataaa
     1081 acgaatgtgt agtggagaaa aaccttacca atgcagaaag tgtggaaaat gttttaggac
     1141 ctattcaagt ctctataggc atcggagaac tcatcctgga gagaaaccct ataaacttac
     1201 agaatgcaat aagtccattc tgtatttatc acaccacaaa gtacattata atatccatta
     1261 tggagaaaaa ccctacaaat gtatagaatg tggtaagtgc tattatcatt catcatttga
     1321 aaaacattac agaattcact ctgaagagga gtcttacaaa tgtaatgatt gtagaaaatc
     1381 ctttatctgc tgcttaggtc ttaaaagaca ccataaaatt catggaggag agaggcctta
     1441 tgaatgtaag caatgtagta agtccttcta tacatcatca caccttgaaa atcattacag
     1501 aacccaccgt agaaaacttc acagatgtaa tgaatgtggc aaatcccttt cctcctcttc
     1561 aggtcttcaa agacatcaga gaattcatag aggagagaaa gcatacatat gtgctgaatg
     1621 taacaaatgc ttcattcaga aatcccaact taaaacacat caaagaattc atacaggaga
     1681 gaaaagttac aaatgtagtg aatgcgagaa atcctttact gttggctcat ctctaagaat
     1741 acatcaaaga attcatactg gagagaaacc ttacaaatgc agtgaatgtc acaagtgctt
     1801 cattcagcaa gcccacctta gaagacatca gaagattcat actggagaga aaccttacaa
     1861 atgtagtgaa tgtgagaaat cctttacagt aggctcggat cttagaatgc atcaaaaaat
     1921 tcatactgga gagaaacctt acaaatgtag tgactgtgat aaatgcttta tccagaaagc
     1981 aaaacttaaa aaacatcaaa gaattcacac aggagagaaa ccttacaaat gtagtgaatg
     2041 tgaaaaatgc tttactgttg tctcggatct tagaacacat cagaaaattc atactggtga
     2101 aaaaccttat aaatgcagtg aatgtgacaa gtgttttatc aggaaagcca accttaggag
     2161 acatcacaga attcatacag gagaaaaacc ttacaaatgc agtgactgtg gcaaatgctt
     2221 tatccagaaa gccaatctta gaactcatga gagaattcat actggagaga aaccttacaa
     2281 atgtgaatgt gggaaatcct ttacagttgg ctcagatctt aggaagcatc agaaatgtca
     2341 tactggagaa aaaccttaca aatgcagtga atgtaacaag tgttttatca ggaaagccca
     2401 ccttagaaga catcaaagaa ttcatactgg agagaaacct tacaaatgta gtgactgtgg
     2461 caaatgcttt atccagaaag ccaatcttag aacacatcag aaaatccaca caggagagaa
     2521 accttacaaa tgtagtgaat gtgacaaatg ctttatccag aaagatcacc taagaacaca
     2581 tcagagactt catacaggag agaaacctta caaatgtagt gaatgtgaaa aatcctttac
     2641 tggtggctca gttcttagaa aacatcagaa aattcatact gcaagaagcc ttactaatgc
     2701 aatgaatttg actaatcctt tatccaagaa gcctacctta gaactcatca aagaatttat
     2761 acaggagagt agccttttaa atgcaatgta tatagcacag tctttacctg cctctcatgt
     2821 ctaagaaaac atcagaaaat tcatatagaa aacaaaagtt tctatagtaa atactgtggc
     2881 atatgcttta gacaagctct gtagtaatag accactacag gtttcacact agagaatcat
     2941 gaacatgaga aacttgagaa cagctttgaa taatgttcaa atgttagaga aaaaaaaaat
     3001 caagactgta taccaaggga aaacgctgca aatgtgacat ttattaaaat gtttcttttt
     3061 caaactcaaa tatttcacaa tgacaacaaa atggagacgc ctgaagaaaa aaatgttctg
     3121 ttgtgtggta ggcttttaaa aattttttat tttaaatttt ttttttaaac taaaacattc
     3181 catccaatac ggaagctgaa taaggcagga aataaactca agacatcttc aggcagtacc
     3241 tgaaactgac aggatttact gtgcttactt tgaagaaact cataccagtt ttgctgctta
     3301 gaagacattt tgatgcattg agccaataag ctataatgcc ctttaaccag tagatgtgac
     3361 tacaggtgtg tagtgtgctc tgggtatcca gtgttcataa actgtatttc atgctggcct
     3421 ggagtttcat ggtgcaactg tctcttactc ctataagcac ctccattctc gtatttatgt
     3481 aagtaaccca ataaagccca ttggttaaac aagatggatt tcagtggcaa gcatacttgg
     3541 ttttgttatg aattcccatt ttagctgagt tgtttctagc caggaaaagt ctctcataca
     3601 acatgtgctg aacccattaa tttttcctca aaacttgtat ggcagaaaat cagtattaga
     3661 gaaaaaacat ttgattaaag tatggaagtt ctttgtgatt actgttccag gcttactact
     3721 atggtagtac atgatcccat taaaaagact caacacagac agcatgtaga ggcttaggga
     3781 gcctgagaaa gaaggctact ctcttccttg tattcatgga ggagagtgag aagtccttgg
     3841 tgagacaaat gaaaatatgg ctataaacct gtgttactga aagacaacat ctaaactggg
     3901 ctatttccat atatgactct gagctcatgc ttagacccca tgattcagtc caactccaat
     3961 gaccctcaga acaccactgt ccatgagcaa atacaaaaaa aagtgctatt ctcatgtcct
     4021 gttgtacttt agaaatccca ctctacaagc ctcatcaaat gaattgaatt ccttttgtta
     4081 aatcctttac acaaagctga aattgtaaac atcagaaaac ttatcatgaa ataaaaccac
     4141 ataaaatgct ttaataaagg cctgtattta ctttaaaaaa aaaaaaaaaa aaaaaaa
//
