LOCUS       NM_027477               3478 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus zinc finger protein 398 (Zfp398), transcript variant
            1, mRNA.
ACCESSION   NM_027477
VERSION     NM_027477.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3478)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3478)
  AUTHORS   Guo,G., Huss,M., Tong,G.Q., Wang,C., Li Sun,L., Clarke,N.D. and
            Robson,P.
  TITLE     Resolution of cell fate decisions revealed by single-cell gene
            expression analysis from zygote to blastocyst
  JOURNAL   Dev Cell 18 (4), 675-685 (2010)
   PUBMED   20412781
REFERENCE   3  (bases 1 to 3478)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   4  (bases 1 to 3478)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK046208.1, AK081169.1, AK078250.1 and BB066614.1.
            
            On Dec 31, 2009 this sequence version replaced NM_027477.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC112382.1, AK081169.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-36                AK046208.1         2-37
            37-2726             AK081169.1         2-2691
            2727-3429           AK078250.1         2298-3000
            3430-3438           BB066614.1         185-193
            3439-3478           AK078250.1         3010-3049
FEATURES             Location/Qualifiers
     source          1..3478
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 22.94 cM"
     gene            1..3478
                     /gene="Zfp398"
                     /gene_synonym="5730513I23Rik"
                     /note="zinc finger protein 398"
                     /db_xref="GeneID:272347"
                     /db_xref="MGI:MGI:1917856"
     exon            1..260
                     /gene="Zfp398"
                     /gene_synonym="5730513I23Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             237..2168
                     /gene="Zfp398"
                     /gene_synonym="5730513I23Rik"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="zinc finger protein 398 isoform 1"
                     /protein_id="NP_081753.1"
                     /db_xref="CCDS:CCDS20099.1"
                     /db_xref="GeneID:272347"
                     /db_xref="MGI:MGI:1917856"
                     /translation="MAEATAAPTSEWDSECLTSLQPLPLPTPPAANEAHLQTAAISLW
                     TVVAAVQAIERKVEVHSRRLLHLEGRTGTAEKKLASCEKTVAELGNQLDGKWAVLGTL
                     LQEYGLLQRRLENLENLLRNRNFWILRLPPGIKGDIPKVPVAFDDVSIYFSTPEWEKL
                     EEWQKELYKNIMKGNYESLISMDYAMNQPDVLSQIQPEGEHSTDDQPRPEASEIPADP
                     SEEPGLSTSDILSWIKQEEEPQVGVSQESKESELYKGTYADEELVIKAEDLARASLCP
                     EVPVAFSAPPPAAAKDAFSDIAFKSQQCTPMAPFARTATDLPEASEGQVTFTQLGSYP
                     LPPPVGEQVFSCHHCGKSLSQDMLMTHQCGHAAEHPLTCAQCPKHFTPQADVGSTSQD
                     HANETPPTCPHCARTFTHPSRLTYHLRVHNSTERPFLCPDCPKRFADQARLTSHRRAH
                     ATERPFRCPQCGRSFSLKISLLLHQRGHAQERPFSCPQCGIDFNGHSALIRHQMIHTG
                     ERPYPCTDCSKSFMRKEHLLNHRRLHTGERPFQCPHCGKSFIRKHHLMKHQRIHTGER
                     PYPCAVCGRSFRYKQTLKDHLRTGHSGGCAGDRDPSVQPPDPPGPLLTALETSGLGVS
                     TEGLESSQWYGEGSGGVVL"
     exon            261..656
                     /gene="Zfp398"
                     /gene_synonym="5730513I23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            657..783
                     /gene="Zfp398"
                     /gene_synonym="5730513I23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            784..897
                     /gene="Zfp398"
                     /gene_synonym="5730513I23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            898..1011
                     /gene="Zfp398"
                     /gene_synonym="5730513I23Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1012..3478
                     /gene="Zfp398"
                     /gene_synonym="5730513I23Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2263..2268
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp398"
                     /gene_synonym="5730513I23Rik"
                     /note="hexamer: CATAAA"
     polyA_site      2290
                     /gene="Zfp398"
                     /gene_synonym="5730513I23Rik"
     regulatory      2697..2702
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp398"
                     /gene_synonym="5730513I23Rik"
                     /note="hexamer: AATACA"
     polyA_site      2728
                     /gene="Zfp398"
                     /gene_synonym="5730513I23Rik"
                     /note="major polyA site"
ORIGIN      
        1 gcctgcagta ctcgctgccc acaaagcgcc agctgagggg cggctgcagc cggtgcggcg
       61 taggctgctc gctactcagc tcctctgcgt cccagcgccc ccggaagccc gattgccgcg
      121 cgagtcctgt cagagcgagc aacgcgagac cgcttctcgc cgtctgccga gagcactgag
      181 cagccgggcc tgcgtgtggt ggcgactccc gggacaggac cgggcagcgg agggccatgg
      241 ctgaggcgac cgccgctccg acttctgaat gggactcgga atgccttaca tccctgcagc
      301 cccttcctct tcctacacct ccagcagcaa atgaggcaca tctgcagact gcagccattt
      361 ccctgtggac agtggtggct gctgtgcagg ccatagagag gaaagtggag gtccacagcc
      421 ggcgactcct ccatctagaa ggcaggacag ggacagcaga gaagaaacta gcaagctgtg
      481 aaaagacagt ggcagagctt gggaaccagc tggatggcaa gtgggccgtg ctggggacct
      541 tgctgcagga gtatgggctg cttcagcggc ggttggagaa cttggagaac ttgttgagaa
      601 acaggaactt ctggatcctg cggctgcccc caggtattaa aggagatatc ccaaaggtgc
      661 ctgtggcctt cgatgacgtc tccatctact tttccacccc agagtgggaa aaattagaag
      721 aatggcaaaa ggaactttac aagaatatca tgaagggcaa ctacgagtct ctcatctcca
      781 tggattatgc catgaatcaa cctgatgttt tatctcagat tcaaccagaa ggagaacaca
      841 gtacagatga ccagccaagg ccagaagcaa gtgagattcc tgcagacccc agtgaagagc
      901 ctggcctttc aacctcagat attctgtctt ggattaaaca agaggaagaa cctcaggttg
      961 gagtctccca ggagtctaaa gagagtgagc tgtacaaagg tacctatgct gatgaagaac
     1021 ttgtcatcaa agctgaagac cttgctagag cttccttgtg tcctgaagtt ccagtagcct
     1081 tctctgctcc accaccagca gcagccaagg atgcattttc agatatagct ttcaaaagcc
     1141 agcagtgtac ccccatggca ccttttgcac gaacggccac tgacctgcct gaagcttcag
     1201 agggacaagt gacttttact cagttaggaa gttacccact cccacctcca gttggagagc
     1261 aggtgttctc atgccaccat tgtggcaaga gtctcagtca agacatgtta atgacacatc
     1321 agtgtggcca tgctgctgaa caccccttaa cctgtgccca gtgtcctaag cacttcaccc
     1381 cacaagcaga tgttggtagc acctcccagg atcatgccaa tgaaacacct cccacctgcc
     1441 ctcactgcgc ccggacattc actcacccct cacgactcac ataccacctt cgggtacaca
     1501 acagcacaga gcgccctttc ctctgtcctg attgtcccaa gcgcttcgct gaccaggctc
     1561 gactcaccag ccatcggcga gctcatgcta ctgagaggcc ctttcgttgc ccacagtgtg
     1621 gtcgtagctt cagccttaag atcagtctcc tgcttcatca gaggggacat gcccaggagc
     1681 gccccttctc ctgtcctcag tgtggcattg acttcaatgg ccactctgca ttgattcgtc
     1741 accaaatgat ccacacaggc gagcgtccct acccgtgcac agactgtagc aagagcttca
     1801 tgcgtaagga acacttgcta aaccaccgga ggctgcacac aggtgagcgg cctttccagt
     1861 gtccgcactg cggcaagagc ttcatccgca agcatcacct catgaagcac cagcgcatcc
     1921 acacaggcga gcgaccatac ccctgtgcag tgtgcggaag gagcttccgc tacaagcaga
     1981 cgctcaagga ccacctacgg accggtcaca gtggaggctg tgcgggtgat agggaccctt
     2041 ccgtacagcc accagaccca cctggtccac tcttaactgc cctggaaacc tctggcctag
     2101 gtgttagcac tgaaggtcta gaatctagtc agtggtatgg ggaagggagt ggaggggtgg
     2161 ttttatagat ctgaggcttg ttggttattt atgttcacag cagagcagaa agtccaggag
     2221 agagcccaca agttccgaaa cctacagtaa ttatatctgt tacataaagg aatttgagat
     2281 ctacactcaa ctagagacat gcttgtgctt tggaaatcca cagcagtata agaatactgt
     2341 attttgaaaa ctggaagaga atccagcacc tctgacttgt cagataccac aaaagcagag
     2401 ttacaaagca agatatggct tctgatcatc ctgtcagagt agcagagtga gagcagactg
     2461 cctctaggca gagacaggtg tatgggaaga gccccaaacc ttgaagccat ccggaggcat
     2521 gagaatgctc agagcgtttc tctaatcgct cagtaattgt tgggaggttg tgctttagcc
     2581 acttgttatg ttgccgtgtg tctgaaacca gctaagttct gctcatatca gtgtagtcac
     2641 ctttccctga gacgtgatga ctgaggctgc attcctaggc ctagattctg tctgctaata
     2701 cattttgttt aatgttggtg aacacgaact ctgactttga tagcttattt aaggggacag
     2761 ttcttagtgt ttactagctt attttgaaat gttcagactc ttgtggcagt tgttaaaaga
     2821 gtagagaact tcaccacagc tctggttagg aaattaggaa gagagttttc tctccaggtt
     2881 taggagctaa agagcccaga gaccccaggc acaacaggga tcatcacatg gcctaaaaaa
     2941 ttatatcaac tcattcctta tcttttccaa gccagtgatc ttgtttttcc atttctggtg
     3001 tttgattctc tttttctttc ttttgagatt gggcctcact gtgtatccag gcctggaact
     3061 ttgctttgta gaccaggctg gccttgaact tacagggatc tgcctgcctc tgcctcatgt
     3121 tctggatgca ccacaattcc caaccccatt ttctttatgg tcctcagcag caaagatcac
     3181 agcactttgt caaggcatca agcacttcag aaagtaccac tgaactcagg gcttttgtcc
     3241 attggtagtg tgatgctctt aaggaaagga tttctacctt gtttgcccct gcctcactgg
     3301 cagtgaacag acaagagacc tctctcggct accaagagct aagtatcata tctatcttac
     3361 ctgttgtgct atttttttca gacagggttt cactgtgggg tcctggctgg tctggaactc
     3421 agagatctgc ctatccctgc atctagagtg ctacgattaa aagcatgctg tcatgccc
//
