LOCUS       NM_013866               2315 bp    mRNA    linear   ROD 13-JUN-2024
DEFINITION  Mus musculus zinc finger protein 385A (Zfp385a), transcript variant
            1, mRNA.
ACCESSION   NM_013866
VERSION     NM_013866.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2315)
  AUTHORS   Tsuboi,D., Kuroda,K., Tanaka,M., Namba,T., Iizuka,Y., Taya,S.,
            Shinoda,T., Hikita,T., Muraoka,S., Iizuka,M., Nimura,A.,
            Mizoguchi,A., Shiina,N., Sokabe,M., Okano,H., Mikoshiba,K. and
            Kaibuchi,K.
  TITLE     Disrupted-in-schizophrenia 1 regulates transport of ITPR1 mRNA for
            synaptic plasticity
  JOURNAL   Nat Neurosci 18 (5), 698-707 (2015)
   PUBMED   25821909
  REMARK    GeneRIF: DISC1 binds ITPR1 mRNA with HZF, thereby regulating its
            dendritic transport for synaptic plasticity.
REFERENCE   2  (bases 1 to 2315)
  AUTHORS   Shimizu,H., Kubo,A., Uchibe,K., Hashimoto,M., Yokoyama,S.,
            Takada,S., Mitsuoka,K. and Asahara,H.
  TITLE     The AERO system: a 3D-like approach for recording gene expression
            patterns in the whole mouse embryo
  JOURNAL   PLoS One 8 (10), e75754 (2013)
   PUBMED   24146773
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2315)
  AUTHORS   Li,R., Yang,Y.G., Gao,Y., Wang,Z.Q. and Tong,W.M.
  TITLE     A distinct response to endogenous DNA damage in the development of
            Nbs1-deficient cortical neurons
  JOURNAL   Cell Res 22 (5), 859-872 (2012)
   PUBMED   22212482
REFERENCE   4  (bases 1 to 2315)
  AUTHORS   Nakamura,H., Kawagishi,H., Watanabe,A., Sugimoto,K., Maruyama,M.
            and Sugimoto,M.
  TITLE     Cooperative role of the RNA-binding proteins Hzf and HuR in p53
            activation
  JOURNAL   Mol Cell Biol 31 (10), 1997-2009 (2011)
   PUBMED   21402775
  REMARK    GeneRIF: Hzf and HuR independently associate with the 3'UTR of p53
            mRNA and together regulate the translation of p53 mRNA and regulate
            the nuclear export of p53 mRNA in response to signals that induce
            p53 activation.
REFERENCE   5  (bases 1 to 2315)
  AUTHORS   Tang,F., Barbacioru,C., Nordman,E., Bao,S., Lee,C., Wang,X.,
            Tuch,B.B., Heard,E., Lao,K. and Surani,M.A.
  TITLE     Deterministic and stochastic allele specific gene expression in
            single mouse blastomeres
  JOURNAL   PLoS One 6 (6), e21208 (2011)
   PUBMED   21731673
REFERENCE   6  (bases 1 to 2315)
  AUTHORS   Iijima,T., Ogura,H., Takatsuki,K., Kawahara,S., Wakabayashi,K.,
            Nakayama,D., Fujioka,M., Kimura,Y., Bernstein,A., Okano,H.J.,
            Kirino,Y. and Okano,H.
  TITLE     Impaired motor functions in mice lacking the RNA-binding protein
            Hzf
  JOURNAL   Neurosci Res 58 (2), 183-189 (2007)
   PUBMED   17383763
  REMARK    GeneRIF: In the present study we demonstrated that mice lacking Hzf
            (Hzf(-/-) mice) exhibited severe impairments of motor coordination
            and cerebellum-dependent motor learning.
REFERENCE   7  (bases 1 to 2315)
  AUTHORS   Iijima,T., Imai,T., Kimura,Y., Bernstein,A., Okano,H.J., Yuzaki,M.
            and Okano,H.
  TITLE     Hzf protein regulates dendritic localization and BDNF-induced
            translation of type 1 inositol 1,4,5-trisphosphate receptor mRNA
  JOURNAL   Proc Natl Acad Sci U S A 102 (47), 17190-17195 (2005)
   PUBMED   16286649
  REMARK    GeneRIF: Hzf is an RNA-binding protein that controls the dendritic
            mRNA localization and activity-dependent translation of type 1
            inositol 1,4,5-trisphosphate receptor mRNA, a process that is
            impaired in Hzf mutant mice
REFERENCE   8  (bases 1 to 2315)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
REFERENCE   9  (bases 1 to 2315)
  AUTHORS   Kimura,Y., Hart,A., Hirashima,M., Wang,C., Holmyard,D., Pittman,J.,
            Pang,X.L., Jackson,C.W. and Bernstein,A.
  TITLE     Zinc finger protein, Hzf, is required for megakaryocyte development
            and hemostasis
  JOURNAL   J Exp Med 195 (7), 941-952 (2002)
   PUBMED   11927637
  REMARK    GeneRIF: Hzf is essential for megakaryopoiesis and hemostasis in
            vivo
REFERENCE   10 (bases 1 to 2315)
  AUTHORS   Hidaka,M., Caruana,G., Stanford,W.L., Sam,M., Correll,P.H. and
            Bernstein,A.
  TITLE     Gene trapping of two novel genes, Hzf and Hhl, expressed in
            hematopoietic cells
  JOURNAL   Mech Dev 90 (1), 3-15 (2000)
   PUBMED   10585558
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC164069.9.
            
            On Sep 9, 2022 this sequence version replaced NM_013866.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK137748.1, AF118566.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-64                AC164069.9         3388-3451
            65-201              AC164069.9         10297-10433
            202-312             AC164069.9         23098-23208
            313-475             AC164069.9         25387-25549
            476-718             AC164069.9         27374-27616
            719-888             AC164069.9         27702-27871
            889-984             AC164069.9         28042-28137
            985-2315            AC164069.9         28273-29603
FEATURES             Location/Qualifiers
     source          1..2315
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 58.88 cM"
     gene            1..2315
                     /gene="Zfp385a"
                     /gene_synonym="Hzf; Zfp385; Znf385a"
                     /note="zinc finger protein 385A"
                     /db_xref="GeneID:29813"
                     /db_xref="MGI:MGI:1352495"
     exon            1..64
                     /gene="Zfp385a"
                     /gene_synonym="Hzf; Zfp385; Znf385a"
                     /inference="alignment:Splign:2.1.0"
     CDS             55..1215
                     /gene="Zfp385a"
                     /gene_synonym="Hzf; Zfp385; Znf385a"
                     /note="isoform 1 is encoded by transcript variant 1; zinc
                     finger protein 385; hematopoietic zinc finger protein"
                     /codon_start=1
                     /product="zinc finger protein 385A isoform 1"
                     /protein_id="NP_038894.2"
                     /db_xref="CCDS:CCDS49743.1"
                     /db_xref="GeneID:29813"
                     /db_xref="MGI:MGI:1352495"
                     /translation="MILGSLSRAGPLPLLRQPPIMQPPMDLKQILPFPLEPAPTLGLF
                     SNYSTMDPVQKAVLSHTFGGPLLKTKRPVISCNVCQIRFNSQSQAEAHYKGNRHARRV
                     KGIEAAKTRGREPSVRESGDPAPAGSIPPSGDGVAPRPVSMENGLGPAPGSPEKQPGS
                     PSPPSVPESGQGVTKGEGGTSVPASLPGGSKEEEEKAKRLLYCALCKVAVNSLSQLEA
                     HNKGTKHKTILEARSGLGPIKAYPRLGPPTPGEPEAPAQDRTFHCEICNVKVNSEVQL
                     KQHISSRRHRDGVAGKPNPLLSRHKKPRGAAELAGTLTFSKELPKSLAGGLLPSPLAV
                     AAVMAAAAGSPLSLRPAPAAPLLQGPPITHPLLHPAPGPIRTAHGPILFSPY"
     exon            65..201
                     /gene="Zfp385a"
                     /gene_synonym="Hzf; Zfp385; Znf385a"
                     /inference="alignment:Splign:2.1.0"
     exon            202..312
                     /gene="Zfp385a"
                     /gene_synonym="Hzf; Zfp385; Znf385a"
                     /inference="alignment:Splign:2.1.0"
     exon            313..475
                     /gene="Zfp385a"
                     /gene_synonym="Hzf; Zfp385; Znf385a"
                     /inference="alignment:Splign:2.1.0"
     exon            476..718
                     /gene="Zfp385a"
                     /gene_synonym="Hzf; Zfp385; Znf385a"
                     /inference="alignment:Splign:2.1.0"
     exon            719..888
                     /gene="Zfp385a"
                     /gene_synonym="Hzf; Zfp385; Znf385a"
                     /inference="alignment:Splign:2.1.0"
     exon            889..984
                     /gene="Zfp385a"
                     /gene_synonym="Hzf; Zfp385; Znf385a"
                     /inference="alignment:Splign:2.1.0"
     exon            985..2315
                     /gene="Zfp385a"
                     /gene_synonym="Hzf; Zfp385; Znf385a"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2287..2292
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp385a"
                     /gene_synonym="Hzf; Zfp385; Znf385a"
                     /note="hexamer: AATAAA"
     polyA_site      2315
                     /gene="Zfp385a"
                     /gene_synonym="Hzf; Zfp385; Znf385a"
                     /note="major polyA site"
ORIGIN      
        1 agaacggccc ccgggacaga acgacgcgga accccgggag ccagggtccc cagcatgatc
       61 ctcggcagcc tgagccgggc agggcccctc cctctgctcc ggcagccccc catcatgcag
      121 ccaccgatgg acctcaagca gatcctgccc ttcccactag agccagcccc aaccctgggc
      181 ctcttcagca actacagcac aatggaccct gtacagaaag ctgtgctctc ccacactttt
      241 ggaggaccct tgctcaagac caagcggcca gtcatttcct gtaatgtctg tcagatccgc
      301 ttcaattctc agagccaggc tgaggcgcac tacaagggta atcgccatgc ccgaagagtc
      361 aaaggcatcg aagctgccaa aacccgaggc agggagccta gtgtccggga atcaggagat
      421 ccagctccag caggcagcat ccctccgagt ggggatggtg tagcccctcg tccagtttcc
      481 atggagaatg gcctgggtcc agctccagga tccccagaga aacagcctgg ctccccatcc
      541 cctcccagtg ttccagagtc gggacagggt gtaaccaagg gtgaaggggg aacttcagtc
      601 ccagcttccc tgcctggggg tagcaaggaa gaggaggaga aggctaagcg tctgctctac
      661 tgtgcactgt gcaaggtggc tgtgaactcc ctgtcccagc ttgaggcaca taacaaaggt
      721 actaagcaca agacaatttt ggaggcccga agtgggctgg gacccatcaa agcttaccct
      781 cggttggggc ctcccactcc tggggaacca gaggctcctg cccaggaccg aaccttccac
      841 tgtgagatct gcaatgtcaa ggtcaattcg gaggtccagc tgaaacagca catctccagc
      901 aggaggcacc gagatggcgt ggctgggaag cccaaccctc tactgagccg gcacaagaag
      961 cctaggggcg ctgcagagct ggcgggcacg ctgactttct caaaggagct gcccaagtcc
     1021 ctggccggtg gcctgctccc cagcccccta gcggtggctg cggtgatggc cgctgcagca
     1081 ggatctccgc tgtccctgcg tccagctcca gctgcacctc ttctgcaggg accaccgatc
     1141 acacaccctc tactccaccc tgccccagga cccatccgaa ctgcgcacgg acccatcctc
     1201 ttctccccct actgacctca accctgaacc cctcccattg aatcccccac ctccagccgg
     1261 gacccaggtc tccgggctcc cagcccgccc ctcttcccgg cgctccctga atggtctctc
     1321 cttcccccca ccccgaggta cggggttcca ggaaagggga ggggtagcgg gggagggggg
     1381 cttcagaagg gggggaacac cccagatctc agggaacccc gccccctgcc cttccctctc
     1441 ccctagaaaa gaggggggcc gtctcacccc cgagccccct cggagacacc ccctcccaaa
     1501 agccatgtcc atccaaccct tcccctccaa acctagcaca aaacggggtt cacaagccat
     1561 ggtcggggcc cggggggaga acatggattt tcttggcaat aagcggactc tgggactccg
     1621 gctcccctac cccaaactaa agcgcttccg tgaacaaccc catcctcccg caggaggagg
     1681 ggaacaggcg ggatcctggg tccctcgtaa gcactttggt tttaccgcct gcaacctcac
     1741 tgtgcccgcc ccgcaccatg ccccagcccc gggtccagtc gggcccatcg cagggggcag
     1801 cacttggggg catctcaggc acttgggtgg gaccaaggag atgccctcat agacccttcc
     1861 ctcgccttct tcctccccgg tccgggttcc attcttttca ccagcaccca tcgcccaagg
     1921 ggtaccaagg ggggcaaggg gtgtccagtc caagcccacc cccgcctcgc cttccgcaaa
     1981 actgtgagca aaaagcaata gaagcctcgc ccccgccccc ggcccgtccc tttccgcagg
     2041 atttgccgtc tgtagcctcc ccattccagt tcctagacct catggctgcc ccctcccgtg
     2101 acacctccac tgcacaactc gggcgggggc gtgaccccca acccgtccct tctgtggttt
     2161 ccgtgtggtc agcccttcca gccgccgacc cgggatgggg actggccccc actggccctc
     2221 ccctccccat ggactctttc tgcttgacaa tgtagcaaac cccctccctc tttctctctc
     2281 cttgacaata aagtctggat ttgttctgcc ctctc
//
