LOCUS       NP_001277279             594 aa            linear   ROD 14-JUN-2024
DEFINITION  zinc finger protein 37 isoform 1 [Mus musculus].
ACCESSION   NP_001277279 XP_006535968 XP_006537862
VERSION     NP_001277279.1
DBSOURCE    REFSEQ: accession NM_001290350.2
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 594)
  AUTHORS   Watanabe,K., Nakayama,K., Ohta,S., Matsumoto,A., Tsuda,H. and
            Iwamoto,S.
  TITLE     ILDR2 stabilization is regulated by its interaction with GRP78
  JOURNAL   Sci Rep 11 (1), 8414 (2021)
   PUBMED   33863978
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 594)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
REFERENCE   3  (residues 1 to 594)
  AUTHORS   Payen,E., Verkerk,T., Michalovich,D., Dreyer,S.D., Winterpacht,A.,
            Lee,B., De Zeeuw,C.I., Grosveld,F. and Galjart,N.
  TITLE     The centromeric/nucleolar chromatin protein ZFP-37 may function to
            specify neuronal nuclear domains
  JOURNAL   J Biol Chem 273 (15), 9099-9109 (1998)
   PUBMED   9535899
REFERENCE   4  (residues 1 to 594)
  AUTHORS   Mazarakis,N., Michalovich,D., Karis,A., Grosveld,F. and Galjart,N.
  TITLE     Zfp-37 is a member of the KRAB zinc finger gene family and is
            expressed in neurons of the developing and adult CNS
  JOURNAL   Genomics 33 (2), 247-257 (1996)
   PUBMED   8660973
REFERENCE   5  (residues 1 to 594)
  AUTHORS   Pilz,A., Woodward,K., Povey,S. and Abbott,C.
  TITLE     Comparative mapping of 50 human chromosome 9 loci in the laboratory
            mouse
  JOURNAL   Genomics 25 (1), 139-149 (1995)
   PUBMED   7774911
REFERENCE   6  (residues 1 to 594)
  AUTHORS   Burke,P.S. and Wolgemuth,D.J.
  TITLE     Zfp-37, a new murine zinc finger encoding gene, is expressed in a
            developmentally regulated pattern in the male germ line
  JOURNAL   Nucleic Acids Res 20 (11), 2827-2834 (1992)
   PUBMED   1614869
REFERENCE   7  (residues 1 to 594)
  AUTHORS   Nelki,D., Dudley,K., Cunningham,P. and Akhavan,M.
  TITLE     Cloning and sequencing of a zinc finger cDNA expressed in mouse
            testis
  JOURNAL   Nucleic Acids Res 18 (12), 3655 (1990)
   PUBMED   2114017
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL683829.15.
            
            On or before Mar 12, 2014 this sequence version replaced
            XP_006537862.1, XP_006535968.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: X89264.1, SRR17784649.1103313.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN01164138
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..594
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 33.04 cM"
     Protein         1..594
                     /product="zinc finger protein 37 isoform 1"
                     /note="male germ cell-specific zinc finger protein; zinc
                     finger protein 37 homolog"
                     /calculated_mol_wt=67095
     Region          1..253
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (P17141.4)"
     Site            3
                     /site_type="phosphorylation"
                     /note="Phosphothreonine.
                     /evidence=ECO:0000250|UniProtKB:O88553; propagated from
                     UniProtKB/Swiss-Prot (P17141.4)"
     Site            9
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:O88553; propagated from
                     UniProtKB/Swiss-Prot (P17141.4)"
     Region          15..62
                     /region_name="KRAB"
                     /note="krueppel associated box; smart00349"
                     /db_xref="CDD:214630"
     Region          124..486
                     /region_name="COG5048"
                     /note="FOG: Zn-finger [General function prediction only]"
                     /db_xref="CDD:227381"
     Region          257..277
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          285..305
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          313..333
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          341..361
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          369..389
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          397..417
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Site            order(402,404,406,408..409,412..413,416,430,432,436..437,
                     440..441,444,458,460,462,464..465,468..469,472)
                     /site_type="other"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]"
                     /db_xref="CDD:275368"
     Region          425..445
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          453..473
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          481..501
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          494..518
                     /region_name="zf-H2C2_2"
                     /note="Zinc-finger double domain; pfam13465"
                     /db_xref="CDD:463886"
     Region          507..529
                     /region_name="zf-C2H2"
                     /note="Zinc finger, C2H2 type; pfam00096"
                     /db_xref="CDD:395048"
     Region          509..529
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          521..545
                     /region_name="zf-H2C2_2"
                     /note="Zinc-finger double domain; pfam13465"
                     /db_xref="CDD:463886"
     Region          537..557
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          550..574
                     /region_name="zf-H2C2_2"
                     /note="Zinc-finger double domain; pfam13465"
                     /db_xref="CDD:463886"
     Region          565..585
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     CDS             1..594
                     /gene="Zfp37"
                     /gene_synonym="Tzn; Zfp-37"
                     /coded_by="NM_001290350.2:88..1872"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /db_xref="CCDS:CCDS71400.1"
                     /db_xref="GeneID:22696"
                     /db_xref="MGI:MGI:99181"
ORIGIN      
        1 matsepaesd avrakeweql epvqrdvykd tklencsnpa smgnqdpkqd ivsvleeeep
       61 ssgkgkkasp sslkkiarpk tagtsaklqq ddehreekqk sqskltkevt lrkkssnskk
      121 sseygllenk slhskhtpse kkllksssrg knsnqnsdsl kkkpdtandh rkslshsasd
      181 vnkdeiptrk kcdklpnnkl sdkgdknqts kkcekvcrhs ashtkedkiq tgekrkshcr
      241 tpskpekapg sgkpyecnhc gkvlshkqgl ldhqrthtge kpyecnecgi afsqkshlvv
      301 hqrthtgekp yeceqcgkah ghkhaltdhl rihtgekpyk cnecgktfrh ssnlmqhlrs
      361 htgekpyeck ecgksfryns sltehvrtht geipyecnec gkafkygssl tkhmrihtge
      421 kpfecnecgk tfskkshlvi hqrthtkekp ykcdecgkaf ghsssltyhm rthtgdcpfe
      481 cnqcgkafkq iegltqhqrv htgekpyecv ecgkafsqks hlivhqrtht gekpfecyec
      541 gkafnaksql vihqrshtge kpyeciecgk afkqnasltk hmkihseeqs eeed
//
