LOCUS       NM_001009549            2613 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus zinc finger protein 36, C3H type-like 3 (Zfp36l3),
            mRNA.
ACCESSION   NM_001009549 XM_285657
VERSION     NM_001009549.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2613)
  AUTHORS   Stumpo,D.J., Trempus,C.S., Tucker,C.J., Huang,W., Li,L.,
            Kluckman,K., Bortner,D.M. and Blackshear,P.J.
  TITLE     Deficiency of the placenta- and yolk sac-specific tristetraprolin
            family member ZFP36L3 identifies likely mRNA targets and an
            unexpected link to placental iron metabolism
  JOURNAL   Development 143 (8), 1424-1433 (2016)
   PUBMED   26952984
  REMARK    GeneRIF: Mice deficient in ZFP36L3 exhibited decreased neonatal
            survival rates, but no apparent morphological changes in the
            placenta or surviving offspring.
REFERENCE   2  (bases 1 to 2613)
  AUTHORS   Frederick,E.D., Ramos,S.B. and Blackshear,P.J.
  TITLE     A unique C-terminal repeat domain maintains the cytosolic
            localization of the placenta-specific tristetraprolin family member
            ZFP36L3
  JOURNAL   J Biol Chem 283 (21), 14792-14800 (2008)
   PUBMED   18367448
  REMARK    GeneRIF: ZFP36L3 is a 'full-time' cytosolic protein, rather than a
            nucleocytoplasmic shuttling protein
REFERENCE   3  (bases 1 to 2613)
  AUTHORS   Blackshear,P.J., Phillips,R.S., Ghosh,S., Ramos,S.B.,
            Richfield,E.K. and Lai,W.S.
  TITLE     Zfp36l3, a rodent X chromosome gene encoding a placenta-specific
            member of the Tristetraprolin family of CCCH tandem zinc finger
            proteins
  JOURNAL   Biol Reprod 73 (2), 297-307 (2005)
   PUBMED   15814898
  REMARK    Erratum:[Biol Reprod. 2005 Nov;73(5):1072. Ramos, Silvia V B
            [corrected to Ramos, Silvia B V]]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AY661338.1, AV223369.2 and BY393504.1.
            
            On Jun 2, 2007 this sequence version replaced NM_001009549.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CF617717.1, AV223369.2 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849384
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2330              AY661338.1         1-2330
            2331-2611           AV223369.2         325-605
            2612-2613           BY393504.1         329-330
FEATURES             Location/Qualifiers
     source          1..2613
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 30.06 cM"
     gene            1..2613
                     /gene="Zfp36l3"
                     /note="zinc finger protein 36, C3H type-like 3"
                     /db_xref="GeneID:333473"
                     /db_xref="MGI:MGI:3525151"
     exon            1..2345
                     /gene="Zfp36l3"
                     /inference="alignment:Splign:2.1.0"
     CDS             150..2327
                     /gene="Zfp36l3"
                     /note="zinc finger protein 36-like 3; zinc finger protein
                     36, C3H1 type-like 3"
                     /codon_start=1
                     /product="mRNA decay activator protein ZFP36L3"
                     /protein_id="NP_001009549.1"
                     /db_xref="CCDS:CCDS30138.1"
                     /db_xref="GeneID:333473"
                     /db_xref="MGI:MGI:3525151"
                     /translation="MANNNLNRPLNTNVADSSNSSSTPGTAPPPSSSDPQVLGHQAPS
                     SSASSLTEDCSSSFARDLNSYNNGQSGATGAVSWEAPHEPSEANAVSQIHPRNGEHSL
                     QQKPKPQKVSGSSSLATSERYKTELCRPFEESGICKYGHKCQFAHGYRELRTLSRHPK
                     YKTEPCRTFHSVGFCPYGTRCHFIHNQPEQQPVLSESTLEEPSSFNGSNVLHLGVNGE
                     QQPGLQSDSPSGFLSVNSQALQAPLQLNQQALSSGGVMPSSHPAAANLRMMCCRTSSS
                     TTAHDADKDPDKDADKDPSNNSANDALAFPQEPGDFSPVAFQNPNTATTTPTAFYNNQ
                     QQMGLAASAQFQMPLARPLPSATIFGQASVGPALTPGAAMAPGAALAPAAALTPAAAL
                     APGAAMALGAAMATGAAMATGAALTPGAALALGAAMAAGAALAPGAAMAPGAAMATGA
                     ALAFGAAMATGTTLTPGAAMALGAAMATGAALAPGAAVAPRAALAPRAAFAPGAAALA
                     PRAALPPGAALTPGAALAPGAALAPRAALPPGATLRPGAALIPRAALAPGAALAPGAA
                     LTPGAALAPGATLAPRAALAPGAALAPRITITSRAAITPGVAIAPGVATASTGILAPG
                     AATATVGNTSSTTITAATAAEGAAPHFTFQLPDVESESESESLEFDVVTSTLDSLLVS
                     DDEDEDDFLRRSSSSSSLNESEFDNTNSSRRLPIFSRFSDSEK"
     exon            2346..2613
                     /gene="Zfp36l3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2589..2594
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp36l3"
                     /note="hexamer: AATAAA"
     polyA_site      2613
                     /gene="Zfp36l3"
                     /note="major polyA site"
ORIGIN      
        1 tcatgtttgg agctcgctgg ctctgcctcc ctcgaaggtt tctccgggtc ctccttactt
       61 aaagctcaaa acggcgcagg acataggaca atgttcacag ttctatggac tttctgcaat
      121 agagacttag agtgcaagac cgagaaacta tggccaacaa caatctgaac cgcccgctca
      181 acactaatgt ggctgattct tccaactcca gctcaacacc tggcactgct ccaccaccat
      241 cttccagcga cccccaagtg ctcggccacc aggctcccag ttccagtgcc tccagcctca
      301 ccgaggactg ctcgtccagt tttgcgagag acctgaacag ctacaataat ggtcagtcgg
      361 gggcaactgg tgcggtgtcc tgggaagctc cccatgagcc ctcagaggct aacgcggtgt
      421 cgcagatcca cccgcggaat ggcgaacata gcctgcagca gaagcctaag ccacagaagg
      481 tgagcggctc gagctccctg gccacttctg agcgctataa gactgagcta tgtcggccct
      541 ttgaggaaag cggcatttgc aagtatggcc acaagtgcca gttcgcgcat ggctaccgcg
      601 aactgcgtac cctgtcaagg caccccaagt acaagacgga gccttgccgc accttccaca
      661 gcgttggctt ttgcccctat ggcactcgct gtcacttcat tcacaaccag cccgagcagc
      721 aacctgtgct ttccgagagc accttggagg agcccagctc cttcaatggc tccaatgtgc
      781 tgcatttggg cgttaacggg gagcagcagc ccggactgca gagtgacagc ccttcgggct
      841 tcctgtcggt caacagtcaa gccctccagg cacctctgca gctcaaccag caggcgttga
      901 gctcaggcgg ggttatgccc tcatcacacc ctgcagccgc caacctccgg atgatgtgct
      961 gcagaacatc atcctctacc acagcccacg acgctgacaa agaccccgac aaagatgctg
     1021 acaaagaccc gagcaacaac tcagccaacg atgccctcgc cttcccccag gagccaggtg
     1081 acttctctcc tgtggcattc cagaacccta acactgctac cacgactccc actgccttct
     1141 acaacaacca gcagcagatg ggcctggcag cttccgcgca gttccagatg ccccttgcca
     1201 ggcctctgcc ttcagccacc atctttggcc aggccagtgt tggtcctgcc cttactcctg
     1261 gtgctgccat ggctcctgga gctgcccttg ctcctgcggc agccctcact cctgcggcag
     1321 cccttgctcc tggggcggcc atggctcttg gagctgccat ggctactggg gctgccatgg
     1381 ctactggagc tgccctcact cctggggcag ccctcgctct tggagctgcc atggctgctg
     1441 gggcggccct tgctcctgga gctgccatgg ctcctggggc tgccatggct actggagcgg
     1501 ccctcgcttt tggggctgcc atggctactg ggactaccct cactcctggg gctgccatgg
     1561 ctcttggtgc tgccatggct actggagctg ccctcgctcc tggggcagca gtggctccta
     1621 gggcggccct tgctcctagg gctgcatttg ctcctggggc ggcggccctc gctcctaggg
     1681 ctgccctccc tcctggagcg gccctcactc ctggggctgc acttgctcct ggggcggccc
     1741 tcgctcctag ggctgccctc cctcctgggg ctaccctccg tcctggggcg gccctcattc
     1801 ctagggcggc ccttgctcct ggggctgccc tcgcccctgg agcggccctc actcctgggg
     1861 ctgcacttgc tcctggggcg acccttgctc ctagggcagc tctcgctcct ggggctgccc
     1921 ttgctcccag aattaccatc acttccaggg ctgccatcac tccgggagtt gctattgctc
     1981 caggagttgc cacagcctct accggcatat tggctccagg tgctgcaact gccactgtgg
     2041 gcaatacatc ctcgactact atcactgctg ccaccgctgc agagggtgcc gcaccacact
     2101 tcaccttcca actgccagat gtcgagtcgg agtctgagtc tgagtcgcta gagttcgacg
     2161 tggtcaccag caccctggat tccctgttgg tcagtgatga cgaagatgaa gacgactttc
     2221 tgaggcgttc ctcgagctcc agcagcctca atgaatccga attcgacaac accaactcca
     2281 gccgccgtct gcccatcttc agccgcttct cagactctga aaaatgaagc aaaaagatgc
     2341 cagtggttag ccacatttgc cacaggtcaa cttctgaagg tggtaggcct tggagctaca
     2401 gcggcggcac agcatatatg tcttattgtg atgctttcca aaggatgaag ttcctttcat
     2461 catcttgctt ctaccagcga ggccaaagag ctagatacgt tcctatatta tgtttgctat
     2521 tattaatgga tgggatataa agatgttctt tccatggttc tatacattta tgtgcatata
     2581 tatctttcaa taaaatgtag tctattaaat gtc
//
