LOCUS       NM_001001806            3537 bp    mRNA    linear   ROD 09-FEB-2025
DEFINITION  Mus musculus zinc finger protein 36, C3H type-like 2 (Zfp36l2),
            mRNA.
ACCESSION   NM_001001806 XM_984899
VERSION     NM_001001806.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3537)
  AUTHORS   Wang,B., Wang,W., Li,J. and Li,J.
  TITLE     Zinc finger protein 36 like 2-histone deacetylase 1 axis is
            involved in the bone responses to mechanical stress
  JOURNAL   Biochim Biophys Acta Mol Basis Dis 1870 (5), 167162 (2024)
   PUBMED   38604490
  REMARK    GeneRIF: Zinc finger protein 36 like 2-histone deacetylase 1 axis
            is involved in the bone responses to mechanical stress.
REFERENCE   2  (bases 1 to 3537)
  AUTHORS   Sunshine,H.L., Cicchetto,A.C., Kaczor-Urbanowicz,K.E., Ma,F.,
            Pi,D., Symons,C., Turner,M., Shukla,V., Christofk,H.R., Vallim,T.A.
            and Iruela-Arispe,M.L.
  TITLE     Endothelial Jagged1 levels and distribution are
            post-transcriptionally controlled by ZFP36 decay proteins
  JOURNAL   Cell Rep 43 (1), 113627 (2024)
   PUBMED   38157296
REFERENCE   3  (bases 1 to 3537)
  AUTHORS   Snyder,B.L., Huang,R., Burkholder,A.B., Donahue,D.R., Mahler,B.W.,
            Bortner,C.D., Lai,W.S. and Blackshear,P.J.
  TITLE     Synergistic roles of tristetraprolin family members in myeloid
            cells in the control of inflammation
  JOURNAL   Life Sci Alliance 7 (1), e202302222 (2023)
   PUBMED   37903626
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3537)
  AUTHORS   Cook,M.E., Bradstreet,T.R., Webber,A.M., Kim,J., Santeford,A.,
            Harris,K.M., Murphy,M.K., Tran,J., Abdalla,N.M., Schwarzkopf,E.A.,
            Greco,S.C., Halabi,C.M., Apte,R.S., Blackshear,P.J. and
            Edelson,B.T.
  TITLE     The ZFP36 family of RNA binding proteins regulates homeostatic and
            autoreactive T cell responses
  JOURNAL   Sci Immunol 7 (76), eabo0981 (2022)
   PUBMED   36269839
REFERENCE   5  (bases 1 to 3537)
  AUTHORS   Redmon,I.C., Ardizzone,M., Hekimoglu,H., Hatfield,B.M.,
            Waldern,J.M., Dey,A., Montgomery,S.A., Laederach,A. and
            Ramos,S.B.V.
  TITLE     Sequence and tissue targeting specificity of ZFP36L2 reveals Elavl2
            as a novel target with co-regulation potential
  JOURNAL   Nucleic Acids Res 50 (7), 4068-4082 (2022)
   PUBMED   35380695
  REMARK    GeneRIF: Sequence and tissue targeting specificity of ZFP36L2
            reveals Elavl2 as a novel target with co-regulation potential.
REFERENCE   6  (bases 1 to 3537)
  AUTHORS   Mattar,P., Britz,O., Johannes,C., Nieto,M., Ma,L., Rebeyka,A.,
            Klenin,N., Polleux,F., Guillemot,F. and Schuurmans,C.
  TITLE     A screen for downstream effectors of Neurogenin2 in the embryonic
            neocortex
  JOURNAL   Dev Biol 273 (2), 373-389 (2004)
   PUBMED   15328020
REFERENCE   7  (bases 1 to 3537)
  AUTHORS   Yoshida,S., Mears,A.J., Friedman,J.S., Carter,T., He,S., Oh,E.,
            Jing,Y., Farjo,R., Fleury,G., Barlow,C., Hero,A.O. and Swaroop,A.
  TITLE     Expression profiling of the developing and mature Nrl-/- mouse
            retina: identification of retinal disease candidates and
            transcriptional regulatory targets of Nrl
  JOURNAL   Hum Mol Genet 13 (14), 1487-1503 (2004)
   PUBMED   15163632
REFERENCE   8  (bases 1 to 3537)
  AUTHORS   Phillips,R.S., Ramos,S.B. and Blackshear,P.J.
  TITLE     Members of the tristetraprolin family of tandem CCCH zinc finger
            proteins exhibit CRM1-dependent nucleocytoplasmic shuttling
  JOURNAL   J Biol Chem 277 (13), 11606-11613 (2002)
   PUBMED   11796723
REFERENCE   9  (bases 1 to 3537)
  AUTHORS   Nie,X.F., Maclean,K.N., Kumar,V., McKay,I.A. and Bustin,S.A.
  TITLE     ERF-2, the human homologue of the murine Tis11d early response gene
  JOURNAL   Gene 152 (2), 285-286 (1995)
   PUBMED   7835719
REFERENCE   10 (bases 1 to 3537)
  AUTHORS   Varnum,B.C., Ma,Q.F., Chi,T.H., Fletcher,B. and Herschman,H.R.
  TITLE     The TIS11 primary response gene is a member of a gene family that
            encodes proteins with a highly conserved sequence containing an
            unusual Cys-His repeat
  JOURNAL   Mol Cell Biol 11 (3), 1754-1758 (1991)
   PUBMED   1996120
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB656287.1 and AC132455.3.
            
            On or before May 4, 2006 this sequence version replaced
            XM_984899.1, NM_001001806.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK170763.1, AK159513.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-610               BB656287.1         2-611
            611-3537            AC132455.3         171629-174555       c
FEATURES             Location/Qualifiers
     source          1..3537
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 55.02 cM"
     gene            1..3537
                     /gene="Zfp36l2"
                     /gene_synonym="Brf2; ERF2; Tis11d"
                     /note="zinc finger protein 36, C3H type-like 2"
                     /db_xref="GeneID:12193"
                     /db_xref="MGI:MGI:107945"
     exon            1..304
                     /gene="Zfp36l2"
                     /gene_synonym="Brf2; ERF2; Tis11d"
                     /inference="alignment:Splign:2.1.0"
     CDS             254..1708
                     /gene="Zfp36l2"
                     /gene_synonym="Brf2; ERF2; Tis11d"
                     /note="butyrate response factor 2; zinc finger protein 36,
                     C3H1 type-like 2; ZFP36-like 2; TPA-induced sequence 11d"
                     /codon_start=1
                     /product="mRNA decay activator protein ZFP36L2"
                     /protein_id="NP_001001806.1"
                     /db_xref="CCDS:CCDS28998.1"
                     /db_xref="GeneID:12193"
                     /db_xref="MGI:MGI:107945"
                     /translation="MSTTLLSPFYDIDFLCKTEKSLANLNLNNMLDKKAVGTPVAAAP
                     SSSFTPGFLRRHSASNLHALAHPVPSPGSCSPKFPGAPNGGGSSCGPAGGGGLASYGQ
                     LKEPSGGSGTALVTKESKFRDRSFSENGERSQHLLHLQQQQKGGSGSQINSTRYKTEL
                     CRPFEESGTCKYGEKCQFAHGFHELRSLTRHPKYKTELCRTFHTIGFCPYGPRCHFIH
                     NADERRPAPSGGGGASGDLRAFGARDALHLGFAREPRPKLHHSLSFSGFPSGHHQPPG
                     GLESPLLLDSPTSRTPPPPSSSASSCSSSASSCSSASAASTPSGAPTCCATAAAAALL
                     YGPGGAEDLLSPGAPCASCSSSGANNAFAFGPELSSLITPLAIQTHNFAAAAAAAYYR
                     NQQQGLTGPAPPPAQPPAAPAPPSPPFGFQLPRRLSESPVFDAPPSPPDSLSDRDSYL
                     SGSLSSGSLSGSESPSLDPGRRLPIFSRLSISDD"
     exon            305..3537
                     /gene="Zfp36l2"
                     /gene_synonym="Brf2; ERF2; Tis11d"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1953..1958
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp36l2"
                     /gene_synonym="Brf2; ERF2; Tis11d"
                     /note="hexamer: AACAAA"
     polyA_site      1990
                     /gene="Zfp36l2"
                     /gene_synonym="Brf2; ERF2; Tis11d"
     regulatory      2630..2635
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp36l2"
                     /gene_synonym="Brf2; ERF2; Tis11d"
                     /note="hexamer: ATTATA"
     polyA_site      2658
                     /gene="Zfp36l2"
                     /gene_synonym="Brf2; ERF2; Tis11d"
ORIGIN      
        1 gagttccacc agtccgcgag ctgccgacgg ctcgggcggg gggcgggccg gggcgccgag
       61 ctgcgctctc gcttctcctc tgccccccac tccgcgccac ggcctcccgc cgccgcttcc
      121 tcggccgcac aagcacaact ttccgtccct ccttggccct cgcccgttat tcatcttggt
      181 tcgagtctcg ccgtaccgag ggcacctccc aacctccacg cttgcaattt cgaccattac
      241 aggacccaga aaaatgtcga ccacacttct gtcacccttc tacgatatcg acttcttgtg
      301 caagacggag aaatccctgg caaacctcaa tctgaacaac atgctggaca agaaggcggt
      361 agggacgccc gtggctgctg cccccagctc gagcttcact ccgggcttcc tgcgacgcca
      421 ctccgccagc aacctccacg cgcttgccca ccctgtgccc agtccgggca gctgctcgcc
      481 gaagttcccg ggcgccccta acggcggcgg cagcagctgt ggccccgcag gcggaggcgg
      541 tctggcctcc tacggccagc tcaaggagcc ttcggggggc agcggcacgg cgctggtcac
      601 caaggagagc aaatttcggg accgctcgtt cagcgagaac ggggagcgca gccagcacct
      661 cctgcacctg cagcagcagc agaagggggg cagcggctcc cagatcaact ccacgcgcta
      721 caagacggag ctgtgccggc ccttcgagga gagcggcacg tgcaagtacg gcgagaagtg
      781 ccagttcgcg cacggcttcc acgagctgcg cagcctcacc cggcacccca agtacaagac
      841 agagctgtgc cgcaccttcc acaccatcgg cttctgcccc tacggcccgc gctgccactt
      901 catccacaac gcggacgagc ggcggcccgc gccgtcgggg ggcggcggcg cctccgggga
      961 cctgcgagcg tttggcgcac gcgacgcgct acacctaggc ttcgcccgcg agccgcggcc
     1021 caagctgcat cacagcctca gtttctccgg cttcccgtcg ggccaccacc agccgccggg
     1081 gggcctggag tcgccgctgc tgctcgacag ccccacatcg cgcacgccgc cgccgccctc
     1141 ctcctcggcc tcgtcctgtt cctcctcggc ttcttcctgc tcttccgcct cggcggcctc
     1201 cacgccctcg ggcgccccga cgtgctgcgc cacggcggcg gcggccgcgc tgctctacgg
     1261 ccccgggggc gcggaggacc tgctgagccc cggagcgccg tgcgcctcct gctcgtcctc
     1321 cggcgctaac aacgccttcg ctttcggccc ggagctgagc agcctcatca cgccgctcgc
     1381 catccagacc cacaacttcg ccgccgcggc cgccgccgcc tactaccgca accagcagca
     1441 gggcctgacc ggtcccgcgc cacccccggc acagcccccc gcggcccccg cgccgccctc
     1501 cccgcccttc ggcttccagc tgccgcgccg tctgtccgag tcgcccgtgt tcgacgcgcc
     1561 ccccagcccc ccggactcgc tctcggaccg cgacagctac ctgagcggct cgctgagctc
     1621 cggcagcctc agcggctccg agtcccccag cctggaccct ggccgtcgcc tacccatctt
     1681 cagccgcctc tccatctccg acgactgagg caagggggcg cccgcgaggg gttgggaaag
     1741 gcacagcggg ggccaccggt tggggagggc gacactgcgg cagacttgga ggcccctccg
     1801 agcacttgga ctcgaactct gccggaaggg gccccgcccc taccctttcg gttctctcgt
     1861 tttttttgtt ttttattatt atttttatta ttattattat tgtaaagatt cgttcttgtt
     1921 gataaaagcc aacgaacttt ttcgtatgga tgaacaaaat attcacaaca gggcggttgt
     1981 gatgcggaaa gaacaaaaga taccaaacac ttaggtctca gatgagtttg aaactctagt
     2041 tttagaagaa aaaaatcagc ccagcaccag cagctaccaa ccaccattcc atctcttctt
     2101 tcactcgaaa gccttagaaa cagtccagat gtgagaactc ttggaagggg ttccaagacc
     2161 agtgtgagcc agccggctgc cacctcccta aactataagc ttctagaact caaaataatg
     2221 ccaggaacat gccttgattc gagtcgctcg ctctcagcct cctttgtggt ggttgtttac
     2281 cttgtttttg ttttttagac aaagttctgt atgtctgggg gtggggaagc ccttgcattc
     2341 caaagtttga taacgggctc attgccacca cgtagtgtgg gtgtttagct tagaaccatt
     2401 tcctctgctc tctggaagct atgggcagag ctcagttcat agttgttggg aaataagtgc
     2461 ttcattttta gttgttctga gttgatccgc accactgcac cacaactcaa tatgaaaaac
     2521 tatttaactt atttattatc ttgtgaaaag tatacattga ggatgttgtc catactgtat
     2581 ttatcgagta tgatgaaagc aatagatata tattctttta ttatgttaaa ttataattgc
     2641 cattattaat cggcaaaatg tggagtgtgt tcttttcaca gtaatatatg ccttttgtaa
     2701 cttcacttgg ttattttatt gtaaatgagt aagaaaaatc ttaatttaag agattgtatg
     2761 taatatttat ttcattaatt tctttccttg tttacgtaaa tttcgaaaga tcgcatgaag
     2821 aaaccatgca atcttgatgc tgtggaagtg gtttgaggaa cattttgagg ttttcttaga
     2881 atgtataatg gttgtagccc atccaacttt aaagagagaa aggtgagact gcagtcaggc
     2941 tcacgtgtgg cttgcttctc tacatccagc tttataaacc accagctcta ctgtgacatt
     3001 gattatagag acatgtagca ataatggggg aaatggtctc agtgccttca tagggcccga
     3061 acttgcctta aatctttctc aaccagataa gtatttcatt cgtgcttgag aatttgaatg
     3121 tcggacgggt tcacctgcac aaaaagaaaa gattttttac cacttttttt ttactatagc
     3181 tatgaagtga agaggccaca tcttagcgct gaaatgttgg tggtacatga atatgccttg
     3241 ttcaatgaca gtccaaaaac ttgtactatt atttttcaat gtaaagaggc aggaatgtct
     3301 ccggctttcc tggatggcag ataaatgagc agttgtttag tttgtatgta ggtacagttg
     3361 gagcaccgcg tgtgcactct ggactacttt gacagaagta ggtttttgaa tgtaacaaga
     3421 ttaagtcaac ttgagttgta atatattttg gggaatcagt tcactacaaa ttgtgactgt
     3481 aaacattgta ctgtaaatgt tttgtagttt cccccaataa aattttttgg aaaaaaa
//
