LOCUS       NM_001419423            3685 bp    mRNA    linear   ROD 28-OCT-2023
DEFINITION  Mus musculus zinc finger protein 362 (Zfp362), transcript variant
            2, mRNA.
ACCESSION   NM_001419423 XM_036164050
VERSION     NM_001419423.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3685)
  AUTHORS   Herppich S, Hoenicke L, Kern F, Kruse F, Smout J, Greweling-Pils
            MC, Geffers R, Burton OT, Liston A, Keller A, Floess S and Huehn J.
  TITLE     Zfp362 potentiates murine colonic inflammation by constraining Treg
            cell function rather than promoting Th17 cell differentiation
  JOURNAL   Eur J Immunol 53 (10), e2250270 (2023)
   PUBMED   37366299
  REMARK    GeneRIF: Zfp362 potentiates murine colonic inflammation by
            constraining Treg cell function rather than promoting Th17 cell
            differentiation.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL611983.23.
            
            On Mar 31, 2023 this sequence version replaced XM_036164050.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: ERR3363658.611932.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164134
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-907               AL611983.23        95618-96524         c
            908-1033            AL611983.23        85050-85175         c
            1034-1097           AL611983.23        80449-80512         c
            1098-1344           AL611983.23        80063-80309         c
            1345-1672           AL611983.23        77092-77419         c
            1673-1897           AL611983.23        76169-76393         c
            1898-1976           AL611983.23        67567-67645         c
            1977-2135           AL611983.23        67283-67441         c
            2136-3685           AL611983.23        63287-64836         c
FEATURES             Location/Qualifiers
     source          1..3685
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 62.25 cM"
     gene            1..3685
                     /gene="Zfp362"
                     /note="zinc finger protein 362"
                     /db_xref="GeneID:230761"
                     /db_xref="MGI:MGI:2652839"
     exon            1..907
                     /gene="Zfp362"
                     /inference="alignment:Splign:2.1.0"
     exon            908..1033
                     /gene="Zfp362"
                     /inference="alignment:Splign:2.1.0"
     CDS             996..2252
                     /gene="Zfp362"
                     /note="isoform a is encoded by transcript variant 2"
                     /codon_start=1
                     /product="zinc finger protein 362 isoform a"
                     /protein_id="NP_001406352.1"
                     /db_xref="GeneID:230761"
                     /db_xref="MGI:MGI:2652839"
                     /translation="MSRSSPSGKGPSRMAEPRFNNPYFWPPPPTMPSQLDNLVLINKI
                     KEQLMAEKIRPPHLPPTSASSQQPLLVPPAPAESSQAVMSLPKLQQVPGLHPQSVPQP
                     DVALHARPATSTVTGLGLSSRTPAVSTSESTPGTGTGTSTPSTPTTTSQSRLIASSPT
                     LISGITSPPLLDSIKTIQGHGLLGPPKSERGRKKIKAENPGGPPVLVVPYPILASGET
                     AKEGKTYRCKVCPLTFFTKSEMQIHSKSHTEAKPHKCPHCSKSFANASYLAQHLRIHL
                     GVKPYHCSYCDKSFRQLSHLQQHTRIHTGDRPYKCPHPGCEKAFTQLSNLQSHQRQHN
                     KDKPYKCPNCYRAYSDSASLQIHLSAHAIKHAKAYCCSMCGRAYTSETYLMKHMSKHT
                     VVEHLVSHHSPQRTESPGIPVRISLI"
     exon            1034..1097
                     /gene="Zfp362"
                     /inference="alignment:Splign:2.1.0"
     exon            1098..1344
                     /gene="Zfp362"
                     /inference="alignment:Splign:2.1.0"
     exon            1345..1672
                     /gene="Zfp362"
                     /inference="alignment:Splign:2.1.0"
     exon            1673..1897
                     /gene="Zfp362"
                     /inference="alignment:Splign:2.1.0"
     exon            1898..1976
                     /gene="Zfp362"
                     /inference="alignment:Splign:2.1.0"
     exon            1977..2135
                     /gene="Zfp362"
                     /inference="alignment:Splign:2.1.0"
     exon            2136..3685
                     /gene="Zfp362"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cccactcgcc ggagccccgg ggccgggcgg gctgcgcagc cgagaggcgg ggggccggac
       61 gcggctcgct cgcggggccc agcgcgccgg ggccgcgcgg ctgcacagcc ggcctccgcc
      121 gccgcggcgc ctgcagaacc cagaagtgaa cagcaggcga cccggaaggt ttgcgcgccg
      181 ctccgcaccg agccccagcc gcgcgccgcc gccaccgccg ccaccgccga agccgggagc
      241 ccccagcccg gccctactcg ggccgccggg ctcggggctg cggccgcgtc ccggagcgcc
      301 gccagcactg ccaggtccgt gcgggcccgg ggcgcgcggg ggagcgggcc cgcccgcggg
      361 aaagttgcgc cgagttgcgg ggcgggggcc gggcgggcgc gagcgctgtc agcgcggggc
      421 ggccgcgctg cgtgggcccg ggggtcgccg gtgcctcggg ccgggccccg gggcggccgt
      481 ggctgcggcg gctgcgcgcg cggggtaggc agcgtctccc gcggcgtgtc tggggttcgt
      541 ctccgagtgt gtgcgtgtgt gttttcctaa gccgggctat tcaaacctgc tgcaattctc
      601 cggtaaacaa tgattcatgg ggcttaatgc aaataaacgg attgcaaacg gcgcggttcg
      661 cgcactttgc agccggcccg gtggagcggc cagtgccgga tttctccgtt tttttgcaga
      721 tctgcagaat atggcgtccc tgtcctgttt taaaaataag ccaggctgcc atttttgttt
      781 ttcttttgtc tgaagatttt aataaaactg tctgagaatg tgggagaggc ggctggaagc
      841 agagggggca cccgaagggt tggctttttt ccttttcttt ggagagagcc gggagccttt
      901 cggggaggtg ccgttgggaa cacagaggaa gtgactgact gggggttcag ggcaagctcc
      961 gtagaagagg gaacccttga gctgggtctt gaaggatgag tagaagctca ccaagtggga
     1021 aaggaccctc taggatggcc gaacctcgat ttaacaaccc gtacttctgg ccccctcctc
     1081 ccaccatgcc gagccagctg gacaacctgg tcctgattaa caagatcaaa gagcagctga
     1141 tggctgaaaa gatccggcca cctcacctgc cacccacctc agcctcatcg cagcagccac
     1201 tgctagtccc tcccgcgccc gccgagagca gccaggcggt catgtcgctg cccaagctgc
     1261 agcaggtgcc cgggctgcac ccgcagtccg tgccgcagcc cgacgtggca ctgcacgcga
     1321 ggccggccac cagtactgtc acaggtctgg ggctttcctc tcgaacccct gctgtgagta
     1381 catctgagtc aaccccaggg actggaacag gcaccagtac cccgtccaca cccaccacca
     1441 ccagccagag ccgcctcatc gcctcatccc ccaccctcat ctcagggatc accagccccc
     1501 cactcctgga ctccatcaag acaatccagg gccacggtct gcttggcccc cccaagtctg
     1561 aacgcggccg gaaaaagatc aaggcagaga acccaggggg tccccctgtc cttgttgtcc
     1621 cgtaccccat cctggcctcc ggtgagaccg caaaggaggg caagacatac aggtgtaagg
     1681 tctgcccgct cacctttttc accaagtctg agatgcagat ccactccaag tcgcacaccg
     1741 aggccaagcc ccacaagtgc ccacactgct ccaagtcctt tgccaacgcc tcctacctgg
     1801 cccagcacct gcgcatccac ctgggtgtca agccctacca ctgctcctac tgtgacaagt
     1861 ccttccggca gctctcccac ctccagcaac ataccagaat ccacacaggc gacagaccat
     1921 acaagtgccc gcatcctggc tgcgaaaagg ctttcactca gctctccaac ctccagtctc
     1981 accagcgcca gcacaataag gacaagccct acaaatgtcc caactgctac cgggcctact
     2041 cagactccgc ctccctccag atccacctct ctgcccatgc catcaagcac gccaaggcct
     2101 actgctgcag catgtgcggg cgggcctaca cctcggagac ctacctgatg aagcacatgt
     2161 ccaaacacac agtggtggaa cacctggtga gccatcactc accccagagg accgagtccc
     2221 ccggcatccc ggtgcgaatc tctctgatct gagccacctg cggcgacgcc ccgcccactt
     2281 ggcagacaca gacccaggca gcacccagcc taattcccgc tggggcctcc aggaaccacc
     2341 aagctctctc acaaccttcc aaacctgcca gaaagcttgg tccacagaag ccctccctgg
     2401 ctggctcctg gcagccaggc caactgcaag attctggact gttctggtgg catccaaaga
     2461 cgatctcaga gcactttgaa cctgtctgtt gggttttctt tttgttcccc ctccctcact
     2521 tgcttcactg tttcttgttt ttaagtttgt tttggaaata acaaaaagga tatttattgg
     2581 ccagaatgtt ggtgctgcta agaacgggaa attaaaagga ctggacagac ggatacagag
     2641 aaccagaggg cagcgtggga acttctctgg ccaaaacctc aggtcttgag gggaggcctg
     2701 gggttctgga cgtcaaaggg gacaccctcc ctcaggtggg aggagacagg agacagctgg
     2761 agtgagccct tcacccgtca cccagtcaaa ctgcctgagc tttgccctag ccttcgtgag
     2821 cagagggcac agcagctgcc aggcctgcct ggctttaggg cacggaaatg agagaggtct
     2881 ggagacccgc gggaccaaag ggtgcagtga cggctgggtg gcaagcccag ggaatgggtt
     2941 gggggcgtgc caggtgagac ctggctcctc ccctgctgcc ctgaagacca ccccagtcta
     3001 cctcggtgct ggccaggaaa cctatcggct acctctccca ccactccaga ctgtgggcag
     3061 ggggatggag agggaggggg cctgggacta agtgcccttt ccagaatttc ttccagaagg
     3121 gtacagtgcc cagggagggg ttgtccttct cgacacagat gaggactccc caacccagac
     3181 cccaggccct gcggcaggga taggagcctc caaaggagga cccaggagca gaccctgccc
     3241 ccagcccccc aagacatatc ccaatccgaa agccatgcgt gtccgtgtat ataggaacta
     3301 tgtacagaac ccagagaagc ccccttccac atcaccccca gagaagaaaa ctagacaaaa
     3361 ctcatctata tattctgtac ctggagtccg tttgaatatt aactgtgtta tttttataca
     3421 ctttttaagc cttaactcgc cattgattta ccagtttaac gtttcctggg gtttcttttc
     3481 cactgggagg gggggtctca gccccccacc cccacccctt tgtttgactt gcgtcgtctg
     3541 atactccgta ttgtagcttt tgtccgcatg ttactaccct gtaaatatgc tgttccaata
     3601 ctgttaacag cctttgcttt ttttctatgg gacctccagg ccaccatatt tagaaatagt
     3661 taccttatta aaaaagagaa aagag
//
