LOCUS       NP_038772                601 aa            linear   ROD 27-APR-2025
DEFINITION  zinc finger protein 354B [Mus musculus].
ACCESSION   NP_038772 XP_923642
VERSION     NP_038772.1
DBSOURCE    REFSEQ: accession NM_013744.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 601)
  AUTHORS   Wajapeyee,N., Malonia,S.K., Palakurthy,R.K. and Green,M.R.
  TITLE     Oncogenic RAS directs silencing of tumor suppressor genes through
            ordered recruitment of transcriptional repressors
  JOURNAL   Genes Dev 27 (20), 2221-2226 (2013)
   PUBMED   24105743
REFERENCE   2  (residues 1 to 601)
  AUTHORS   Taher,L., Collette,N.M., Murugesh,D., Maxwell,E., Ovcharenko,I. and
            Loots,G.G.
  TITLE     Global gene expression analysis of murine limb development
  JOURNAL   PLoS One 6 (12), e28358 (2011)
   PUBMED   22174793
REFERENCE   3  (residues 1 to 601)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   4  (residues 1 to 601)
  AUTHORS   Tekki-Kessaris,N., Bonventre,J.V. and Boulter,C.A.
  TITLE     Characterization of the mouse Kid1 gene and identification of a
            highly related gene, Kid2
  JOURNAL   Gene 240 (1), 13-22 (1999)
   PUBMED   10564808
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK148756.1 and BC107400.1.
            
            On Dec 7, 2005 this sequence version replaced XP_923642.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK148756.1, BB623813.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849382, SAMN00849384
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..601
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 30.95 cM"
     Protein         1..601
                     /product="zinc finger protein 354B"
                     /note="transcription factor 17-like 1; kidney, ischemia,
                     and developmentally-regulated protein 2"
                     /calculated_mol_wt=68533
     Region          14..73
                     /region_name="KRAB"
                     /note="krueppel associated box; smart00349"
                     /db_xref="CDD:214630"
     Region          182..585
                     /region_name="COG5048"
                     /note="FOG: Zn-finger [General function prediction only]"
                     /db_xref="CDD:227381"
     Region          208..228
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          236..256
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Site            order(241,243,245,247..248,251..252,255,269,271,275..276,
                     279..280,283,297,299,301,303..304,307..308,311)
                     /site_type="other"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]"
                     /db_xref="CDD:275368"
     Region          264..284
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          292..312
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          345..365
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Site            order(350,352,354,356..357,360..361,364,378,380,384..385,
                     388..389,392,406,408,410,412..413,416..417,420)
                     /site_type="other"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]"
                     /db_xref="CDD:275368"
     Region          373..393
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          401..421
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          429..449
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          457..477
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          485..505
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Site            order(490,492,494,496..497,500..501,504,518,520,524..525,
                     528..529,532,546,548,550,552..553,556..557,560)
                     /site_type="other"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]"
                     /db_xref="CDD:275368"
     Region          513..533
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          541..561
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          569..589
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     CDS             1..601
                     /gene="Zfp354b"
                     /gene_synonym="Kid2; Tcf17l1; Znf354b"
                     /coded_by="NM_013744.3:184..1989"
                     /db_xref="CCDS:CCDS24641.1"
                     /db_xref="GeneID:27274"
                     /db_xref="MGI:MGI:1351476"
ORIGIN      
        1 mapeqregks qvsvtfedva vlftrdewkk lvpsqrslyr evmlenysnl aslgfpftkp
       61 kmisvlqqge epwksekesh gcsplgchgs lqttkstqtk eslfqelkrk qlkrdeawdf
      121 tsgkscrpdn sfrtqdtnes leiisinhtk iltidksrkn fkfgpsvglk sigkqkiage
      181 ktqrnsleen stllsqpklk tvekrykcst cekafihnss lrkhlknhtg erlfqckdcl
      241 kafsqssali qhqrthtgek pyickecgka fshsaslckh lrthtleksy tckecgksfs
      301 rrsglflhqk iharenphky npgrkastsl sgcqrihsrk ktylcnecgn tfksssslry
      361 hqrihtgekp fkcsecgraf sqsasliqhe rihtgekpyr csecgkgfts isrlnrhrii
      421 htgekfyncn ecgkalsshs tliiheriht gekpckckvc gkafrqssal iqhqrmhtge
      481 rpykcnecgk tfrcnsslsn hqrthtgekp yrcqecgmsf gqsaaliqhr rihtgekpfk
      541 cntcgksfrq sssliahqri htgekpyecs acgklfsqrs sltnhyrihi eedalnidlh
      601 e
//
