LOCUS       NM_001111107            4919 bp    mRNA    linear   ROD 05-JUN-2024
DEFINITION  Mus musculus zinc finger protein 322A (Zfp322a), transcript variant
            1, mRNA.
ACCESSION   NM_001111107
VERSION     NM_001111107.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4919)
  AUTHORS   Ma,H., Ng,H.M., Teh,X., Li,H., Lee,Y.H., Chong,Y.M., Loh,Y.H.,
            Collins,J.J., Feng,B., Yang,H. and Wu,Q.
  TITLE     Zfp322a Regulates mouse ES cell pluripotency and enhances
            reprogramming efficiency
  JOURNAL   PLoS Genet 10 (2), e1004038 (2014)
   PUBMED   24550733
  REMARK    GeneRIF: our results demonstrate that Zfp322a is a novel essential
            component of the transcription factor network which maintains the
            identity of mouse ES cells.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4919)
  AUTHORS   Guo,G., Huss,M., Tong,G.Q., Wang,C., Li Sun,L., Clarke,N.D. and
            Robson,P.
  TITLE     Resolution of cell fate decisions revealed by single-cell gene
            expression analysis from zygote to blastocyst
  JOURNAL   Dev Cell 18 (4), 675-685 (2010)
   PUBMED   20412781
REFERENCE   3  (bases 1 to 4919)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   4  (bases 1 to 4919)
  AUTHORS   Yoshikawa,T., Piao,Y., Zhong,J., Matoba,R., Carter,M.G., Wang,Y.,
            Goldberg,I. and Ko,M.S.
  TITLE     High-throughput screen for genes predominantly expressed in the ICM
            of mouse blastocysts by whole mount in situ hybridization
  JOURNAL   Gene Expr Patterns 6 (2), 213-224 (2006)
   PUBMED   16325481
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK036302.1, CF743666.1 and AL669819.13.
            
            On Oct 31, 2013 this sequence version replaced NM_001111107.1.
            
            Transcript Variant: This variant (1) differs in the 5' UTR,
            compared to variant 3. Variants 1-4 encode the same protein.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR9219383.27263.1,
                                           SRR9219382.128140.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164134, SAMN01164135
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-233               AK036302.1         2-234
            234-308             CF743666.1         505-579
            309-2480            AK036302.1         235-2406
            2481-4919           AL669819.13        128797-131235       c
FEATURES             Location/Qualifiers
     source          1..4919
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 9.55 cM"
     gene            1..4919
                     /gene="Zfp322a"
                     /gene_synonym="Znf322; Znf322a"
                     /note="zinc finger protein 322A"
                     /db_xref="GeneID:218100"
                     /db_xref="MGI:MGI:2442566"
     exon            1..74
                     /gene="Zfp322a"
                     /gene_synonym="Znf322; Znf322a"
                     /inference="alignment:Splign:2.1.0"
     exon            75..160
                     /gene="Zfp322a"
                     /gene_synonym="Znf322; Znf322a"
                     /inference="alignment:Splign:2.1.0"
     exon            161..233
                     /gene="Zfp322a"
                     /gene_synonym="Znf322; Znf322a"
                     /inference="alignment:Splign:2.1.0"
     exon            234..308
                     /gene="Zfp322a"
                     /gene_synonym="Znf322; Znf322a"
                     /inference="alignment:Splign:2.1.0"
     exon            309..4919
                     /gene="Zfp322a"
                     /gene_synonym="Znf322; Znf322a"
                     /inference="alignment:Splign:2.1.0"
     CDS             452..1684
                     /gene="Zfp322a"
                     /gene_synonym="Znf322; Znf322a"
                     /codon_start=1
                     /product="zinc finger protein 322"
                     /protein_id="NP_001104577.1"
                     /db_xref="CCDS:CCDS26337.1"
                     /db_xref="GeneID:218100"
                     /db_xref="MGI:MGI:2442566"
                     /translation="MENHLGENHRRCTLQKRNVTRELKKGKHTMYALKRVKKIYIRVH
                     EITQIDNQTYQCLEREQNFCENLARMCERTYTEEKPYRCDMCEKTFIQSSDLISHQRI
                     HNYEKPYKCSKCEKSFWHHLALSGHQRTHAGKKFYTCDICGKNFGQSSDLLVHQRSHT
                     GEKPYLCNECDKCFSRSTNLIRHRRTHTGEKPFKCLECEKAFSGKSDLISHQRTHTGE
                     RPYKCNKCEKSYRHRSAFIVHKRVHTGEKPYKCGACEKCFGQKSDLIVHQRVHTGEKP
                     YKCLECMRSFTRSANLIRHQATHTHTFKCLEYEKSFNCSSDFIVHQRIHMEEKPHQWS
                     MCESDFLLGMDFVAQQKMRAQTEELHYKYSVCDKTFHHSSALLQHQTVHIDDEYICNM
                     SEKGLDLSSHASETSRVS"
     regulatory      2661..2666
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp322a"
                     /gene_synonym="Znf322; Znf322a"
                     /note="hexamer: AATAAA"
     polyA_site      2680
                     /gene="Zfp322a"
                     /gene_synonym="Znf322; Znf322a"
                     /note="major polyA site"
     regulatory      4893..4898
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp322a"
                     /gene_synonym="Znf322; Znf322a"
                     /note="hexamer: AATAAA"
     polyA_site      4919
                     /gene="Zfp322a"
                     /gene_synonym="Znf322; Znf322a"
                     /note="major polyA site"
ORIGIN      
        1 ggctacgcct ccctgtcctt gctggtgaga gcggtttgtc ttggccttgt ggtgtgcggg
       61 gaccgcttct ccaggagagg gaagaattaa atattatgag tacttctgga ttagagacct
      121 tgtggatctg aaaaaaataa atcgttgggt tcttgttaag aaagctgttt tttttaattt
      181 tgattttctc aagacataaa gtgaaggctg cttttcatct gtctgcacta tcggtctgtg
      241 cactgtgtag gcctgttgcc catgggagcc agaagagtgt tgatgccctg gaactggagt
      301 tacagaaggt ttggaggtac caagtaagaa actaatgtat atgatgctgg aaacttttaa
      361 acacaaactg caaatgaatg aaaggcttaa aaaagatata tttttgaagt taccagaaaa
      421 atgactatga aaacagggat caagaagact gatggaaaac cacttaggag agaaccatag
      481 aagatgtaca cttcagaaga ggaatgtaac cagagaactc aaaaaaggaa aacataccat
      541 gtatgccctc aaaagggtga aaaagattta tattcgtgta catgagatta ctcaaataga
      601 taatcaaaca tatcagtgcc ttgaacgtga acaaaacttt tgtgaaaact tagcacgaat
      661 gtgtgagaga acatataccg aggagaaacc ttatagatgt gatatgtgtg agaaaacctt
      721 catccaaagt tcagatctta tttcccacca gaggatccat aattacgaga aaccttataa
      781 gtgtagcaaa tgtgagaaga gcttttggca ccacttagcc ctttcaggac accagagaac
      841 acatgcaggt aaaaagtttt atacctgtga catctgtggc aagaattttg gtcagagctc
      901 tgatctgctt gtccaccagc gaagccatac aggtgaaaaa ccttatctgt gtaatgagtg
      961 tgataaatgc ttcagtcgaa gtacaaatct cataaggcac cgaagaactc acacaggtga
     1021 gaaaccgttt aagtgtctgg aatgtgaaaa agcttttagt gggaaatcag atcttattag
     1081 ccaccaaagg actcataccg gtgaaaggcc ctacaaatgc aataaatgtg agaaaagtta
     1141 ccgacaccgg tctgccttca ttgtgcataa aagagttcat actggggaga agccgtacaa
     1201 gtgtggtgcc tgtgagaagt gctttggcca gaaatcagac cttattgtac accagagagt
     1261 ccatacagga gagaaaccat ataaatgctt ggagtgtatg agaagtttta ctcgaagtgc
     1321 caacctaatt aggcaccagg caactcacac tcatactttc aaatgccttg aatatgagaa
     1381 aagtttcaac tgtagctcag actttattgt acatcagaga attcatatgg aagaaaaacc
     1441 acatcaatgg tctatgtgtg agagtgactt cctcctaggt atggacttcg ttgcccagca
     1501 gaaaatgagg gctcaaacag aggagctcca ttataaatac agtgtatgtg ataaaacctt
     1561 tcatcatagc tcagcccttc ttcaacatca gacagtgcac attgatgatg aatacatctg
     1621 taacatgagt gaaaaagggc ttgatctaag ttctcacgca tcggaaacct cacgtgtgtc
     1681 ttgacaagat gtcatgtaac cttaaaaata tatttacata tcagaattca ataagtgaaa
     1741 gactcctagg taaatttcag atttccctta gatctcagac ttcattggag ttcagagagt
     1801 ctacagtctt aggaactgta agaaaagttt aaatgcagag agtggccctg tcaggacacc
     1861 tttattagcc acagttgcca agaactccac aaatgctctg ggttttggaa aaccatcaca
     1921 agattcatac aggtaggaag ccttacaatg cagtatgcga gctctccagc agggttaagt
     1981 cctcattttt acaagacaag tcacaccaga gaacaaccat gtaaatgttt tgtattggca
     2041 gtacttcaga cagtgtgtat gtcttattgg atatcagaaa aatcaccctg gggagaagcc
     2101 ccagacatta gaggaaaaag cttcttacag aactctgact tccttacctc tcagacaagc
     2161 catactgggg taaatggata tttgggtgtg gcgaaaacat gtgttggaga gtcatacttg
     2221 ggtttccatc ctcctagatg aaaatcagag gagcaataag tatctgaatg aggaaagttt
     2281 attaatgttc agctcttgga gcatatcagg gaactcacat tagtgaaaac ccgtaaatgc
     2341 attgtgtctg agaagctaga aagacgtctt atttagtcag gccccagaga atgagttcct
     2401 cagaggagtt gttccagtaa gagatctaat tgtgggtgag aatctgtata tatgctgttc
     2461 atagttgaac cacattgtgg aaaaaaaaat gaaaaaacta gacttgtatg gaaataatgt
     2521 cctagcaacc caaaagcttg ttctggagga gccggggcag gtcagcgtgg atctggaggg
     2581 taactcaggt aaagatgctt ttcttttgtc tcagccaatt aatgattgct ttagtttcac
     2641 tttaaaaatt tcataaatcc aataaaggaa agaactgtaa tcttgtgtat aagtagggtg
     2701 tggtttattg ttggaagaaa gcagtgcttt gagttttgct tcctgtttgg ttttcctgtg
     2761 cgtttcttaa aatctcatgg ctagaatggg aatggtgtgt tactaagaag ctaaagagta
     2821 cttagtttgg gttaaaattc ttagcttccc tttggcatga tcaacctcag caaaaaccag
     2881 aacactcagt tctttgctta gtgttgacat ctgcccttag aattgtccta agatgtctaa
     2941 aatttctttt tgagttatca ctggggtcgt tgaaatttca tatttataga ttaatttatt
     3001 ttcaagtcaa aattttagga caaattttag gatcctggtt atcatattat agtattcagg
     3061 attttgtgac ttgcttcatc tctttcagtg atagatactt taacagctgg cttagagcag
     3121 aaggaatagg gggcaagttg taagccagag aaagtagagg agcgatgcaa tgaagcatta
     3181 aaaaaaaaaa aaaagattta tttattatta tacataagta cactgtagct gtcttcagac
     3241 accagaagag ggcgtcagat ctcactccgg gtggttgtga gctaccatgt ggttgctggg
     3301 atttgaactc aaggaccttt ggaagagcag tcagtggtct taccactgag ccatctcgct
     3361 agcccaatga agcattttaa tagagaaaca ggacactgat tttgaggatc ctgactccaa
     3421 agctaatgtc cttcttcagt ctattatcct gatactcgca gcaattaagc ttcataatga
     3481 catttttttt tcatttattt cagttctatc aaggaaagaa aaatacaatt taattccaga
     3541 gacaggattg cagtcaacac aatataaggt atattcttgg tttggaatgc aggattcaaa
     3601 ttgttagaaa agtagtccgc agattgacct gaagtttaag gataaatgtg tgtttccagt
     3661 ccagtggggt aactgattgt ctttcacact ctttggatag ctcatgaccc aagcatttgt
     3721 caaatggtca cttctcattt gctttctttg acttaaaaga cttaattcaa atatatcaag
     3781 ttcctgtata tttgagactg tatagaatta taattatttt attgctaatc aataattgtc
     3841 atggttttag tgtaagttct ctagtgaact cctgaattcc agggggtatt agtgtttgga
     3901 gtcacaaaat tattctggtg ctaccttacc tgtgactgta agctctcgac ctgataattg
     3961 tttgataatc ataatcctga ggccagtgaa tttagctcag taaagaatct ggttcaagta
     4021 tttttccttt ttagaaaact gattgtgtca gttgttttgt tcgattttgt tggtttggtt
     4081 tggtttggtt tggtttggtt ttctgagact gggtttttct gtatagccct ggctgttctg
     4141 gaactagcta tgttgaccag gctggcctca aacttacaga gctcctcctg cctctgcctc
     4201 cctagtgcta ggattaaagg catgcactac aaccacctgt ctctgtgtca aattttttga
     4261 tctaatatgt tccagtaatt ttataaataa ctttagtact atgaacaatt tatccattgt
     4321 gataaataca catgagatgc atatttttct ttttggggaa aatcatgcct tatcactagt
     4381 aaaagtttaa aattgtgata tttaatactg ggtgtgtaac aatggcagtt tacaaaagaa
     4441 aaaaaaaaag gttattataa tagaaacacc atggagaaag agacaaactt aaaccatcag
     4501 taggttggtg atttaccctt ccttcagcct gtctcactgg gaattgtcta tagtctgaaa
     4561 ttaccttaat agtggaccat tcctcaaaca gaactttgag gatgtaaatc aggcctgagg
     4621 ccttttaact gtagtaagaa ggggttggta ttaaataaca taacctgagg ttggagaaga
     4681 ccacttggga gcctgtaacc aaagctagaa ggtaacttct gggatggatg gagttcccct
     4741 tgaagcagtg ccaacgcaag tctacctcag gtaagtagtc agagtaacta tttcaagatt
     4801 tcagagcaaa tgagataaat catgttccat cccatgtact ccgctatgct tattggtttt
     4861 ttgttgttgt tgttgttgac ctttaattct taaataaaga tttgttgtga aatactcca
//
