LOCUS       NM_022409               1530 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Mus musculus zinc finger protein 296 (Zfp296), mRNA.
ACCESSION   NM_022409
VERSION     NM_022409.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1530)
  AUTHORS   Miyazaki,S., Yamano,H., Motooka,D., Tashiro,F., Matsuura,T.,
            Miyazaki,T. and Miyazaki,J.I.
  TITLE     Zfp296 knockout enhances chromatin accessibility and induces a
            unique state of pluripotency in embryonic stem cells
  JOURNAL   Commun Biol 6 (1), 771 (2023)
   PUBMED   37488353
  REMARK    GeneRIF: Zfp296 knockout enhances chromatin accessibility and
            induces a unique state of pluripotency in embryonic stem cells.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1530)
  AUTHORS   Yao,S.Q., Wang,M., Liang,J.J., Ng,T.K. and Cen,L.P.
  TITLE     Retinal transcriptome of neonatal mice after optic nerve injury
  JOURNAL   PLoS One 18 (5), e0286344 (2023)
   PUBMED   37252932
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1530)
  AUTHORS   Mizoue,Y., Ikeda,T., Ikegami,T., Riabets,O., Oishi,Y., Tobita,M.,
            Akutsu,H., Hattori,K., Heissig,B. and Koide,H.
  TITLE     The stem cell transcription factor ZFP296 transforms NIH3T3 cells
            and promotes anchorage-independent growth of cancer cells
  JOURNAL   Int J Dev Biol 67 (4), 147-153 (2023)
   PUBMED   38334180
  REMARK    GeneRIF: The stem cell transcription factor ZFP296 transforms
            NIH3T3 cells and promotes anchorage-independent growth of cancer
            cells.
REFERENCE   4  (bases 1 to 1530)
  AUTHORS   Catela,C., Chen,Y., Weng,Y., Wen,K. and Kratsios,P.
  TITLE     Control of spinal motor neuron terminal differentiation through
            sustained Hoxc8 gene activity
  JOURNAL   Elife 11, e70766 (2022)
   PUBMED   35315772
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1530)
  AUTHORS   Yamamoto,H., Kon,T., Omori,Y. and Furukawa,T.
  TITLE     Functional and Evolutionary Diversification of Otx2 and Crx in
            Vertebrate Retinal Photoreceptor and Bipolar Cell Development
  JOURNAL   Cell Rep 30 (3), 658-671 (2020)
   PUBMED   31968244
REFERENCE   6  (bases 1 to 1530)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   7  (bases 1 to 1530)
  AUTHORS   Evsikov,A.V., Graber,J.H., Brockman,J.M., Hampl,A., Holbrook,A.E.,
            Singh,P., Eppig,J.J., Solter,D. and Knowles,B.B.
  TITLE     Cracking the egg: molecular dynamics and evolutionary aspects of
            the transition from the fully grown oocyte to embryo
  JOURNAL   Genes Dev 20 (19), 2713-2727 (2006)
   PUBMED   17015433
REFERENCE   8  (bases 1 to 1530)
  AUTHORS   Yoshikawa,T., Piao,Y., Zhong,J., Matoba,R., Carter,M.G., Wang,Y.,
            Goldberg,I. and Ko,M.S.
  TITLE     High-throughput screen for genes predominantly expressed in the ICM
            of mouse blastocysts by whole mount in situ hybridization
  JOURNAL   Gene Expr Patterns 6 (2), 213-224 (2006)
   PUBMED   16325481
REFERENCE   9  (bases 1 to 1530)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   10 (bases 1 to 1530)
  AUTHORS   Dear,T.N.
  TITLE     Cloning, structure, expression analysis, and assignment to mouse
            chromosome 7 of the gene Zfp296 encoding a zinc finger protein
  JOURNAL   Mamm Genome 11 (11), 1037-1039 (2000)
   PUBMED   11063263
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DV647330.1, AK008748.1, BE635089.1 and BE634620.1.
            
            On Apr 22, 2010 this sequence version replaced NM_022409.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DV647330.1, AK008748.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-35                DV647330.1         1-35
            36-423              AK008748.1         2-389
            424-924             BE635089.1         1-501
            925-1079            AK008748.1         891-1045
            1080-1530           BE634620.1         5-455               c
FEATURES             Location/Qualifiers
     source          1..1530
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 9.93 cM"
     gene            1..1530
                     /gene="Zfp296"
                     /gene_synonym="2210018A16Rik; Znf296"
                     /note="zinc finger protein 296"
                     /db_xref="GeneID:63872"
                     /db_xref="MGI:MGI:1926956"
     exon            1..342
                     /gene="Zfp296"
                     /gene_synonym="2210018A16Rik; Znf296"
                     /inference="alignment:Splign:2.1.0"
     CDS             96..1433
                     /gene="Zfp296"
                     /gene_synonym="2210018A16Rik; Znf296"
                     /note="hepatocellular carcinoma-associated antigen
                     MHCA108"
                     /codon_start=1
                     /product="zinc finger protein 296"
                     /protein_id="NP_071854.2"
                     /db_xref="CCDS:CCDS52060.1"
                     /db_xref="GeneID:63872"
                     /db_xref="MGI:MGI:1926956"
                     /translation="MSRRKAGRVPRRVDPDTDTDIEMPDLVMDVKPDLDLRSLAQGPW
                     IARDMPISDVKRQLQTASRPLGAPSTCAPRMPLSSKSSDRQPWTDKHPDLLTCGRCGK
                     IFPLGAIIAFMDHKKQGCQLLQVSDPISESKELKALSCLQCGRQYTSPWKLLCHAQWD
                     HGLCIYQTQHLDTPEAPLLGLAEVAAAMSAVAVVAPVESKPPPVSSAARRSPTCDVCK
                     KTLSSFSNLKVHMRSHTGERPYSCDQCSYACAQSSKLNRHKKTHRQLAPGSPSTSASS
                     RGVSPAAPPEPAAYAAAPASTLPSQTVEKAGAAATAGVQEPGAPGSGAQGGPGFVGWG
                     APAKVERTDPVKIEKTAPRKSHGPGGKCEFCGKSFTNSSNLTVHRRSHTGERPYTCDQ
                     CPYACAQSSKLNRHRRTHGLGTGKTVKCPHCLVPFGLQATLDKHLRQKHPEMA"
     exon            343..486
                     /gene="Zfp296"
                     /gene_synonym="2210018A16Rik; Znf296"
                     /inference="alignment:Splign:2.1.0"
     exon            487..1530
                     /gene="Zfp296"
                     /gene_synonym="2210018A16Rik; Znf296"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1505..1510
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp296"
                     /gene_synonym="2210018A16Rik; Znf296"
                     /note="hexamer: AATAAA"
     polyA_site      1530
                     /gene="Zfp296"
                     /gene_synonym="2210018A16Rik; Znf296"
                     /note="major polyA site"
ORIGIN      
        1 cacgtgtaaa aagttcggcg cgggtcgccc agagccactc actcacctga gcgcctggcc
       61 accgcgcgga ttacctggat ctgcgccctc tccccatgtc ccgccgcaag gccggccgcg
      121 tgcctcgccg cgtagatccc gataccgaca ccgacattga gatgcccgat cttgtcatgg
      181 atgtaaagcc ggacctcgac ttgaggtccc tggcgcaggg gccctggatc gcgagggaca
      241 tgcccatatc ggatgtgaag cgtcaactcc aaactgcctc gcgcccactc ggcgcgccca
      301 gcacgtgtgc cccgcggatg cctctgagtt ctaagtcttc cgaccgccag ccatggaccg
      361 acaagcaccc agatctgttg acctgcggcc gttgcgggaa gatctttcca ttaggggcca
      421 tcatcgcttt catggatcac aaaaaacaag gctgtcagct tctccaagtc tccgacccca
      481 tctcagaatc caaagagctg aaggctctga gctgcctcca gtgtggcaga cagtacacta
      541 gtccttggaa gttgctgtgc cacgcccagt gggaccatgg gctatgcatc taccagacac
      601 aacacctaga taccccagag gctccgctgc tgggcctggc tgaggtggca gcagccatgt
      661 cagcagtggc agtggtggcg ccagttgaaa gcaagccccc tccagtgagc agtgctgccc
      721 ggcggagccc cacctgtgat gtgtgcaaga agaccctcag ctctttcagc aacctcaagg
      781 tccacatgcg ttcccacact ggtgagcgac cctactcctg tgaccagtgt tcctatgcct
      841 gcgctcagag cagcaagctc aacagacaca agaagaccca tcggcagctg gcacccggga
      901 gcccctccac ttctgccagt agcaggggag tctccccagc agcccctcct gaaccagctg
      961 cctacgcagc tgctccagcc agcacactcc caagccagac tgtggagaag gctggagctg
     1021 cagccacagc aggagtccag gaacctgggg cccctggcag cggagctcaa gggggtccag
     1081 gttttgttgg ctggggagcc cctgccaaag tagagaggac tgaccctgta aagatcgaga
     1141 agacagcacc taggaagagt catgggcctg ggggcaagtg tgagttctgc gggaagtcct
     1201 tcaccaacag cagcaacctg accgtgcacc gacgttcaca cactggtgag cggccctata
     1261 cctgtgacca gtgtccctat gcttgtgccc agagtagcaa gctcaaccgc caccgtcgca
     1321 cccatggtct ggggactggt aaaactgtca agtgcccgca ctgccttgtg ccctttggct
     1381 tgcaggccac actggacaag cacctgcggc agaagcaccc agagatggcc tgagccatat
     1441 tctctgtaca ggtgtcacta aagcaagtgg aaatgggcag gcactttagt cttttctctg
     1501 tgtgaataaa ccatctcctt tttattctta
//
