LOCUS       NM_133208               5043 bp    mRNA    linear   ROD 12-FEB-2025
DEFINITION  Mus musculus zinc finger protein 287 (Zfp287), transcript variant
            1, mRNA.
ACCESSION   NM_133208 XM_006532380
VERSION     NM_133208.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5043)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 5043)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 5043)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   4  (bases 1 to 5043)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   5  (bases 1 to 5043)
  AUTHORS   Blanchard,A.D., Page,K.R., Watkin,H., Hayward,P., Wong,T.,
            Bartholomew,M., Quint,D.J., Daly,M., Garcia-Lopez,J. and
            Champion,B.R.
  TITLE     Identification and characterization of SKAT-2, a novel Th2-specific
            zinc finger gene
  JOURNAL   Eur J Immunol 30 (11), 3100-3110 (2000)
   PUBMED   11093124
REFERENCE   6  (bases 1 to 5043)
  AUTHORS   Agata,Y., Matsuda,E. and Shimizu,A.
  TITLE     Rapid and efficient cloning of cDNAs encoding Kruppel-like zinc
            finger proteins by degenerate PCR
  JOURNAL   Gene 213 (1-2), 55-64 (1998)
   PUBMED   9630514
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL627097.6.
            
            On or before May 22, 2020 this sequence version replaced
            XM_006532380.3, NM_133208.2.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7652917.871639.1,
                                           SRR9219380.70365.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-230               AL627097.6         59517-59746         c
            231-834             AL627097.6         56132-56735         c
            835-938             AL627097.6         55400-55503         c
            939-1065            AL627097.6         53098-53224         c
            1066-1152           AL627097.6         52647-52733         c
            1153-5043           AL627097.6         39336-43226         c
FEATURES             Location/Qualifiers
     source          1..5043
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 38.62 cM"
     gene            1..5043
                     /gene="Zfp287"
                     /gene_synonym="B230333C16Rik; mszf16; mszf74; SKAT-2;
                     Skat2; zfp-287; Znf287"
                     /note="zinc finger protein 287"
                     /db_xref="GeneID:170740"
                     /db_xref="MGI:MGI:2176561"
     exon            1..230
                     /gene="Zfp287"
                     /gene_synonym="B230333C16Rik; mszf16; mszf74; SKAT-2;
                     Skat2; zfp-287; Znf287"
                     /inference="alignment:Splign:2.1.0"
     exon            231..834
                     /gene="Zfp287"
                     /gene_synonym="B230333C16Rik; mszf16; mszf74; SKAT-2;
                     Skat2; zfp-287; Znf287"
                     /inference="alignment:Splign:2.1.0"
     CDS             450..2729
                     /gene="Zfp287"
                     /gene_synonym="B230333C16Rik; mszf16; mszf74; SKAT-2;
                     Skat2; zfp-287; Znf287"
                     /note="isoform 1 is encoded by transcript variant 1; zinc
                     finger protein SKAT2; zinc finger protein SKAT-2"
                     /codon_start=1
                     /product="zinc finger protein 287 isoform 1"
                     /protein_id="NP_573471.2"
                     /db_xref="CCDS:CCDS24830.1"
                     /db_xref="GeneID:170740"
                     /db_xref="MGI:MGI:2176561"
                     /translation="MANSSLSQVLLMWKPGKIQKGPCSAEQQTLTSRLLRDTETCRRN
                     FRNFPYPDVAGPRKALCQLRELCLKWLRPEVHSKEQILELLVLEQFLSILPGEVRTWV
                     NSQYPESSEEVVALVEDLTQILEEEEAPQSSALPQDTPEDDPNHDPNPASQAGWLSDV
                     VTKDLVTFNDVAVDITQEDWELMPPVQKELYKTVTLQNYWNMVSLGLTVYRPTVIPVL
                     EEPWMVIKEIVEGPNPEWEPKAQAQCPAKHLPELKQDGTQTVKLEDSYDDDNDDSVES
                     PPVCAFGMIHIDEEGFSVKSELSQEDPTEEYLSKCDIYRVTFEKHTNLGVQFDTQSDD
                     KTALYNESKPPFSNASSGGAVRGKILPGDKPYSCNVCGKQFRKYPSLLAHRENHAKEK
                     AYECEECGKEFKHLSSLIAHQRMHTGEKPYECHQCGKAFSQRAHLTIHQRIHTGEKPY
                     KCEDCGKDFSQRAHLTIHQRTHTGEKPYKCLECSKTFSHSSSLINHQRVHTGEKPYIC
                     NECGKTFSQSTHLLQHQKIHTGKKPYKCNECWKVFSQSTYLIRHQRIHSGEKCYKCTA
                     CGKAFAHSSTLIQHQTTHTGEKSYICNVCGKAFSQSANLTQHHRTHTGEKPYKCSVCG
                     KAFSQSVHLTQHQRIHNGEKPFKCNTCGKAYRQGANLTQHQRVHTGEKPYKCHHCGKA
                     FIYSSSLNQHRRTHTGERPYKCSHCNKDFSQRTCLIQHQRIHTGEKPYGCRICGKAFT
                     QSTNLIQHQRVHTGARHRN"
     exon            835..938
                     /gene="Zfp287"
                     /gene_synonym="B230333C16Rik; mszf16; mszf74; SKAT-2;
                     Skat2; zfp-287; Znf287"
                     /inference="alignment:Splign:2.1.0"
     exon            939..1065
                     /gene="Zfp287"
                     /gene_synonym="B230333C16Rik; mszf16; mszf74; SKAT-2;
                     Skat2; zfp-287; Znf287"
                     /inference="alignment:Splign:2.1.0"
     exon            1066..1152
                     /gene="Zfp287"
                     /gene_synonym="B230333C16Rik; mszf16; mszf74; SKAT-2;
                     Skat2; zfp-287; Znf287"
                     /inference="alignment:Splign:2.1.0"
     exon            1153..5043
                     /gene="Zfp287"
                     /gene_synonym="B230333C16Rik; mszf16; mszf74; SKAT-2;
                     Skat2; zfp-287; Znf287"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      2807
                     /gene="Zfp287"
                     /gene_synonym="B230333C16Rik; mszf16; mszf74; SKAT-2;
                     Skat2; zfp-287; Znf287"
     regulatory      5024..5029
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp287"
                     /gene_synonym="B230333C16Rik; mszf16; mszf74; SKAT-2;
                     Skat2; zfp-287; Znf287"
                     /note="hexamer: AATAGA"
     polyA_site      5043
                     /gene="Zfp287"
                     /gene_synonym="B230333C16Rik; mszf16; mszf74; SKAT-2;
                     Skat2; zfp-287; Znf287"
                     /note="major polyA site"
ORIGIN      
        1 gcagtggcgc cgaggcgagg tcgctgcgaa gcccgggagc taggggttcc ggccggggcc
       61 tctggggacc cggctggaat gagcgtgtac tgacggctcc cggctcctcc cagggagaga
      121 agcggtgaag ctgagcccct gatgcagctc tgagtcgagc ctgccacgga ggctcccgcc
      181 acgccgccgc cattgttgcc cgggctgcgc cgacggggcc cgagtgacag ggtcttgctc
      241 atctttgcaa gttctggact cagaatttgt tacaagacac taacttttat cgtggttcca
      301 ttctggacct ggcctcagca gcccttgggg ggaaaaaatt gttgtgactg tcacatgaga
      361 cttcaaacag ttggctcaat tctggaaaaa taaagggtac tgtcaggtag gtcctcctgt
      421 ctgtagcagt gttggcctcg agagagaaga tggcaaattc ttcactttcc caagtccttc
      481 taatgtggaa gccaggcaag atccagaagg gaccctgcag tgctgagcag cagacactca
      541 cctcaagact cttgcgtgac actgaaacct gtcgacggaa ttttagaaat ttcccatacc
      601 cggatgtggc aggccctcgg aaagcgttgt gtcagctccg agagctctgc ctgaagtggc
      661 tgagacctga ggttcattcc aaggaacaaa ttctggagtt gctggtgctg gagcaatttc
      721 tgagcatcct gcctggggag gttaggactt gggtaaattc tcagtaccca gagagcagcg
      781 aagaagtggt ggctttggtg gaggatttga ctcagatcct agaagaagaa gaagctcctc
      841 agagttctgc cctcccccaa gacaccccag aggatgaccc caaccatgac cccaaccctg
      901 cttcccaggc agggtggctc agtgacgtgg tgaccaaaga cttggtgaca ttcaatgacg
      961 tggctgtgga catcacccaa gaagactggg aactgatgcc ccctgttcag aaggaattgt
     1021 ataagactgt gactttacag aactattgga acatggtttc tctaggactg actgtgtaca
     1081 ggccaactgt gattcccgtc ttagaagagc cgtggatggt gataaaagaa attgtagaag
     1141 gccctaatcc agaatgggaa cctaaagctc aggcacagtg cccagcaaag catctccctg
     1201 aactcaagca ggacggaacc caaaccgtaa aactggaaga ttcctatgac gacgacaacg
     1261 atgacagcgt agagagtccg ccagtgtgtg ccttcgggat gatccacata gatgaggaag
     1321 gcttcagtgt gaagtcagag ctttcacaag aagaccctac agaagaatac cttagcaaat
     1381 gtgacatata tagagtgact tttgaaaagc acacaaacct aggggtccag tttgataccc
     1441 agtcggatga taaaactgct ctgtataatg aaagcaagcc accgttcagc aatgcctcgt
     1501 ctggtggtgc cgtgcgtggg aaaatacttc ctggagataa gccttattcc tgtaatgtct
     1561 gtgggaaaca gtttagaaag tacccttccc tcctggcgca ccgagagaac cacgccaaag
     1621 agaaagctta tgagtgtgaa gaatgcggca aagaatttaa gcatctctcc tccctcatcg
     1681 cacatcagag aatgcacacc ggagaaaaac cgtacgaatg ccaccagtgt gggaaagcct
     1741 tcagtcagcg agcacacctg actatacacc agagaattca cactggagag aaaccctaca
     1801 aatgtgagga ctgtgggaaa gacttcagtc agcgcgcgca cctcaccatc catcaaagga
     1861 cacacactgg ggagaagccg tataaatgtc tggagtgcag taaaaccttt agccatagtt
     1921 catcactgat taatcatcag agagttcata ctggagaaaa accttatata tgcaacgaat
     1981 gtgggaagac tttcagtcag agcacgcacc ttctccagca tcagaaaatc cacactggga
     2041 aaaagccgta caagtgcaac gagtgttgga aagtgttcag ccagagcact tacctcatcc
     2101 gacaccagag aatccattct ggagagaagt gctacaaatg cactgcctgt gggaaggcct
     2161 ttgcccactc ctcaactctc attcaacatc agaccaccca caccggagag aagtcctata
     2221 tatgcaacgt gtgtgggaaa gccttcagcc aaagcgccaa ccttacccag catcatagaa
     2281 cacacactgg agagaaaccg tacaaatgta gtgtgtgtgg aaaagccttc agccagagtg
     2341 tgcacctcac ccagcaccag aggattcaca atggagaaaa gccctttaag tgtaatacct
     2401 gtgggaaagc ttacagacag ggtgcaaacc tgactcagca ccaacgggtc cacactggag
     2461 agaagcccta caaatgtcac cactgcggga aagcctttat ctactcttca tcccttaacc
     2521 aacatcgaag aactcacact ggagagcgac cctataagtg tagtcactgt aacaaagatt
     2581 ttagccagag aacatgcctt attcaacacc agaggattca cacaggagaa aagccctacg
     2641 gatgccgtat atgtgggaaa gccttcaccc agagtaccaa tcttattcag catcagcggg
     2701 ttcatacggg tgccagacat cgcaattgac agatatgaga gactttgttt atgctttaaa
     2761 acttgattgc ttaaatttca ttgtgtgctc tgtcaaaata cccaaaagaa acctaaagac
     2821 gtgcaatatg cttgatacca cagtgtcaga aagtcccaga agtggtaggt aaaatggctc
     2881 tcatccattt agatttagtg tgagattcaa agctccatca actagctagc ttttatctgg
     2941 tatcacttga attcattcca gaaagaaata ctaggaaagg acaattcata acctgtgatt
     3001 cttcaactct tcgtatattt caagtatgtt ttattgaggc cttaggagta tgccttggga
     3061 aaacacctgt caagggggtc tcacacaaga gagtaatcct gacattatag gaaagagggt
     3121 agatgcttcg gggcctttgc ttcatcctat ctttgaagcc ttaaagtaag taaaaggtcc
     3181 caatttttgc tccctctttt cccattgcaa cttccatgtg aagccagtaa gtaaagctcg
     3241 aggagaagga agacctgaaa agctcttaaa aggtttctgc gtgaccgttg ctaactacac
     3301 tttgtagacg tgaacaggaa gagaaggcgg tctggtgggg taggggacca gcatatccaa
     3361 agccctagac atgtacgaac tcagacacag gttaaacacc ccagcctaaa gtcatctgta
     3421 gtacaacagt atacttagtt tctcatggtt tcgacatcca gtgtcaccct gaaggaaaaa
     3481 agacaggcat ggtgttcccc tttcccccca cctggctgtt aaattgacaa gttttcctat
     3541 ggttcttatt gttcaaaagc tatttcctcc attggagcac acttcttgag agcctactgt
     3601 gctcaggaca tagacttatt attgttattg ttgttgttac taatattcat ggtttgtttt
     3661 aatgtaggag tgctctgtct gcatatacac ctacatgcca aaagagggca tcagatccca
     3721 ttacagatgg ttgtgagcca ccatgtggtt gctgggaact gaactcagaa cctctggaag
     3781 agcaggcagt gttcctaacc actgagccat ctctccagcc ctgacacaga cttcttgatt
     3841 gaaccacttc agttaacaaa gaaataagca acgtgagaat gagtgatgga gagtgggttt
     3901 gggtccagtg cagaggtagt gagagaaagc caggatggaa aggagtgagg agggagagta
     3961 cgcaaacagc ccacgtgaca tgaaatataa ttgcacccgc tttatccaag gaaacaatag
     4021 tggtaaaaac agaaaattag gctatttata agaagctaga aagaaaatca ttttcagaaa
     4081 taattagaag taacatttta aaattacact taatgtggct aggaaaacat ttcattgggg
     4141 aaaaaaagcc ttggtgcaga aatgatcatt aatcaggaat cacaaaatga taactgagtc
     4201 cgtggggcat aaacaccata aaaggaagac tggcaggaac caatttttta attaattttt
     4261 ttacaaactg taattacagt ttaattaatg ttgtgtttac tctccatagt gtcacactct
     4321 cagaacactc agctgagctt caccctgctc gcccttgtcc ctccagtgcc ttgcataagg
     4381 tcagtatatt ggtgggattg acagtgagtt ctgtaaactg gagttgagta gttaaggtag
     4441 aatcaccggc atggaaagag aatgggcggg accgaaagca acctctgtgc ccatgtgtca
     4501 cgtctgacag tttactgtga aatgacagct caagaatgga gactcagaag tggtgggaca
     4561 ccgttcccaa gggaagcccc cgagctaagt gagaggaaac aagttctggt gccataaatt
     4621 cctaagctta tattgacagt atagcatcac tagacaccac agcagggaat gaagaacagg
     4681 tccaggcgat cctaacggga gtgctttctt aagggaattg tcactttctc cttcctgaca
     4741 ttagttatct tgacttcgta gtattcacag agcactggtt aaagacatgc tcagactata
     4801 cttgccccac agttttgtta aggataacaa gtgcgtttac tatgcttctt gatgttgctt
     4861 catgccttga taacgcttct ttccgctggg atgagtgtgg cgtggtacag gccacagggc
     4921 ggaactttgt gtttcttacc tttgtgcgtt ttttgtaaat aatgcattta taaagtcttc
     4981 cactggttca cgggggcaag taaggctcct atttaaaaaa aaaaatagaa taacagtaca
     5041 gaa
//
