LOCUS       NM_001382824            2832 bp    mRNA    linear   ROD 12-FEB-2025
DEFINITION  Mus musculus zinc finger protein 287 (Zfp287), transcript variant
            3, mRNA.
ACCESSION   NM_001382824 XM_006532382
VERSION     NM_001382824.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2832)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2832)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2832)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   4  (bases 1 to 2832)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   5  (bases 1 to 2832)
  AUTHORS   Blanchard,A.D., Page,K.R., Watkin,H., Hayward,P., Wong,T.,
            Bartholomew,M., Quint,D.J., Daly,M., Garcia-Lopez,J. and
            Champion,B.R.
  TITLE     Identification and characterization of SKAT-2, a novel Th2-specific
            zinc finger gene
  JOURNAL   Eur J Immunol 30 (11), 3100-3110 (2000)
   PUBMED   11093124
REFERENCE   6  (bases 1 to 2832)
  AUTHORS   Agata,Y., Matsuda,E. and Shimizu,A.
  TITLE     Rapid and efficient cloning of cDNAs encoding Kruppel-like zinc
            finger proteins by degenerate PCR
  JOURNAL   Gene 213 (1-2), 55-64 (1998)
   PUBMED   9630514
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL627097.6.
            
            On May 22, 2020 this sequence version replaced XM_006532382.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660815.102008.1,
                                           SRR7345562.1147739.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849382, SAMN01164139
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-230               AL627097.6         59517-59746         c
            231-834             AL627097.6         56132-56735         c
            835-938             AL627097.6         55400-55503         c
            939-1065            AL627097.6         53098-53224         c
            1066-1152           AL627097.6         52647-52733         c
            1153-2832           AL627097.6         49104-50783         c
FEATURES             Location/Qualifiers
     source          1..2832
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 38.62 cM"
     gene            1..2832
                     /gene="Zfp287"
                     /gene_synonym="B230333C16Rik; mszf16; mszf74; SKAT-2;
                     Skat2; zfp-287; Znf287"
                     /note="zinc finger protein 287"
                     /db_xref="GeneID:170740"
                     /db_xref="MGI:MGI:2176561"
     exon            1..230
                     /gene="Zfp287"
                     /gene_synonym="B230333C16Rik; mszf16; mszf74; SKAT-2;
                     Skat2; zfp-287; Znf287"
                     /inference="alignment:Splign:2.1.0"
     exon            231..834
                     /gene="Zfp287"
                     /gene_synonym="B230333C16Rik; mszf16; mszf74; SKAT-2;
                     Skat2; zfp-287; Znf287"
                     /inference="alignment:Splign:2.1.0"
     CDS             450..1307
                     /gene="Zfp287"
                     /gene_synonym="B230333C16Rik; mszf16; mszf74; SKAT-2;
                     Skat2; zfp-287; Znf287"
                     /note="isoform 3 is encoded by transcript variant 3; zinc
                     finger protein SKAT2; zinc finger protein SKAT-2"
                     /codon_start=1
                     /product="zinc finger protein 287 isoform 3"
                     /protein_id="NP_001369753.1"
                     /db_xref="GeneID:170740"
                     /db_xref="MGI:MGI:2176561"
                     /translation="MANSSLSQVLLMWKPGKIQKGPCSAEQQTLTSRLLRDTETCRRN
                     FRNFPYPDVAGPRKALCQLRELCLKWLRPEVHSKEQILELLVLEQFLSILPGEVRTWV
                     NSQYPESSEEVVALVEDLTQILEEEEAPQSSALPQDTPEDDPNHDPNPASQAGWLSDV
                     VTKDLVTFNDVAVDITQEDWELMPPVQKELYKTVTLQNYWNMVSLGLTVYRPTVIPVL
                     EEPWMVIKEIVEGPNPGRQTCRTVGSLIHGTTHPSGVMSCSCSFEHLKDALSVPALIH
                     LLAPVSRPF"
     exon            835..938
                     /gene="Zfp287"
                     /gene_synonym="B230333C16Rik; mszf16; mszf74; SKAT-2;
                     Skat2; zfp-287; Znf287"
                     /inference="alignment:Splign:2.1.0"
     exon            939..1065
                     /gene="Zfp287"
                     /gene_synonym="B230333C16Rik; mszf16; mszf74; SKAT-2;
                     Skat2; zfp-287; Znf287"
                     /inference="alignment:Splign:2.1.0"
     exon            1066..1152
                     /gene="Zfp287"
                     /gene_synonym="B230333C16Rik; mszf16; mszf74; SKAT-2;
                     Skat2; zfp-287; Znf287"
                     /inference="alignment:Splign:2.1.0"
     exon            1153..2832
                     /gene="Zfp287"
                     /gene_synonym="B230333C16Rik; mszf16; mszf74; SKAT-2;
                     Skat2; zfp-287; Znf287"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2490..2495
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp287"
                     /gene_synonym="B230333C16Rik; mszf16; mszf74; SKAT-2;
                     Skat2; zfp-287; Znf287"
                     /note="hexamer: ATTAAA"
     polyA_site      2509
                     /gene="Zfp287"
                     /gene_synonym="B230333C16Rik; mszf16; mszf74; SKAT-2;
                     Skat2; zfp-287; Znf287"
                     /note="major polyA site"
     regulatory      2736..2741
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp287"
                     /gene_synonym="B230333C16Rik; mszf16; mszf74; SKAT-2;
                     Skat2; zfp-287; Znf287"
                     /note="hexamer: AATAGA"
     polyA_site      2754
                     /gene="Zfp287"
                     /gene_synonym="B230333C16Rik; mszf16; mszf74; SKAT-2;
                     Skat2; zfp-287; Znf287"
     regulatory      2808..2813
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp287"
                     /gene_synonym="B230333C16Rik; mszf16; mszf74; SKAT-2;
                     Skat2; zfp-287; Znf287"
                     /note="hexamer: AACAAA"
     polyA_site      2832
                     /gene="Zfp287"
                     /gene_synonym="B230333C16Rik; mszf16; mszf74; SKAT-2;
                     Skat2; zfp-287; Znf287"
                     /note="major polyA site"
ORIGIN      
        1 gcagtggcgc cgaggcgagg tcgctgcgaa gcccgggagc taggggttcc ggccggggcc
       61 tctggggacc cggctggaat gagcgtgtac tgacggctcc cggctcctcc cagggagaga
      121 agcggtgaag ctgagcccct gatgcagctc tgagtcgagc ctgccacgga ggctcccgcc
      181 acgccgccgc cattgttgcc cgggctgcgc cgacggggcc cgagtgacag ggtcttgctc
      241 atctttgcaa gttctggact cagaatttgt tacaagacac taacttttat cgtggttcca
      301 ttctggacct ggcctcagca gcccttgggg ggaaaaaatt gttgtgactg tcacatgaga
      361 cttcaaacag ttggctcaat tctggaaaaa taaagggtac tgtcaggtag gtcctcctgt
      421 ctgtagcagt gttggcctcg agagagaaga tggcaaattc ttcactttcc caagtccttc
      481 taatgtggaa gccaggcaag atccagaagg gaccctgcag tgctgagcag cagacactca
      541 cctcaagact cttgcgtgac actgaaacct gtcgacggaa ttttagaaat ttcccatacc
      601 cggatgtggc aggccctcgg aaagcgttgt gtcagctccg agagctctgc ctgaagtggc
      661 tgagacctga ggttcattcc aaggaacaaa ttctggagtt gctggtgctg gagcaatttc
      721 tgagcatcct gcctggggag gttaggactt gggtaaattc tcagtaccca gagagcagcg
      781 aagaagtggt ggctttggtg gaggatttga ctcagatcct agaagaagaa gaagctcctc
      841 agagttctgc cctcccccaa gacaccccag aggatgaccc caaccatgac cccaaccctg
      901 cttcccaggc agggtggctc agtgacgtgg tgaccaaaga cttggtgaca ttcaatgacg
      961 tggctgtgga catcacccaa gaagactggg aactgatgcc ccctgttcag aaggaattgt
     1021 ataagactgt gactttacag aactattgga acatggtttc tctaggactg actgtgtaca
     1081 ggccaactgt gattcccgtc ttagaagagc cgtggatggt gataaaagaa attgtagaag
     1141 gccctaatcc aggacgacaa acctgtagaa cagtcggaag cttgattcat ggaaccaccc
     1201 atccatctgg agtcatgagt tgttcctgct catttgagca tctcaaggat gccctctcag
     1261 tcccggctct catccacctg ctagctcctg tctctcgtcc cttctaatgt gtaactgtcc
     1321 ccaggctcct ttcccttact ggctggttcc cgcggtccct tctttccggt tggttggttg
     1381 gttggttgtt cagcgtacag aggacatcct ttgacgcttt ctcacacact tagctttggt
     1441 ggttctcatc ccttatccct tcttctcctc tctccactgt gctcttccac cctccaagca
     1501 ccctgcttcc ctttcgcagc tcatgtggcc tgtgactctc cccacctcat gaaccccttt
     1561 ctaattccct ggccattgct cacatctata tgtgatgcgt gtttaacgac tagaaactta
     1621 aggggccagc aaaataccac tgtgggtaaa attgctttcc acacaagcct ggcgacctga
     1681 ccctaggtca cctaaaaata gaaggagata ccaggcacca caaaattgtc ctccaacctc
     1741 cacacgcatg tctgaggcac acatatgcac gcatgtgcac acacggttaa ttttctaata
     1801 aatgaaaagg aaaacaatta gaagctggga gtctctggtg agagaaagct ctaccagagg
     1861 tgtctgtctt tctgagcctg ggttacccga ctcagtgtgt cttccagatc catccatttc
     1921 cctacaaact gatggaattc catcgtgtcc cacatcgtca ttaccattca tgtgtcggtg
     1981 agcatctagg ctgactccat ttccttgcta gtgtgaaagg aagagcagtg agcgagcaga
     2041 gatgaccagg acgtaggttc ctttgggtgt gtgctcggaa gtggtgagct ggtcatgtgg
     2101 cgtacctttt agttttttaa gaaatctccg tattggcttc cattatgtat agaccttttt
     2161 tttttttctt ttttcccccc tcttttttag tcttttatta ttataatgaa agtcttttat
     2221 gatcataatt tttatgataa aaatatgggt cgaagatagt cttttttaca gagtgatcct
     2281 gatttctcca ctgtctcaca gatagattta atttaaactg tctgttgcct gattgactgt
     2341 ttatttgttg gttgtttgag acagagtctc tacctggtct caaattcact atgtaaacct
     2401 ggctggctgc agctcagaga tctacctgcc cgtccctctg cctcccaaac gctgggattg
     2461 aaagtgtgca tcacggcagc tggtctccca ttaaacacct ttgctctcag tcagtgttac
     2521 tttccatgtc tttcttcagc cactccatct taaccgctgc tgtctttggt gacgatcagt
     2581 ttggagaatg cagtgtgtgt gttaaggggg tggggttttc ccctgtaaca atttgtgaaa
     2641 agtttgatcc cgaggccacg tgactgttgc gttccctgtg ttgtgttgga tgcacaggag
     2701 tgatttccta acttagtcat ctcttctgca cgataaatag aattcttgtg taaagtctgc
     2761 ctccctttct tcctatcacg tttctatgtg tgaaccatta tccactaaac aaatttttac
     2821 aagttcaagg ta
//
