LOCUS       NM_138949               3057 bp    mRNA    linear   ROD 01-MAY-2024
DEFINITION  Mus musculus zinc finger protein 286 (Zfp286), transcript variant
            1, mRNA.
ACCESSION   NM_138949
VERSION     NM_138949.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3057)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3057)
  AUTHORS   Horiuchi,K., Perez-Cerezales,S., Papasaikas,P., Ramos-Ibeas,P.,
            Lopez-Cardona,A.P., Laguna-Barraza,R., Fonseca Balvis,N.,
            Pericuesta,E., Fernandez-Gonzalez,R., Planells,B., Viera,A.,
            Suja,J.A., Ross,P.J., Alen,F., Orio,L., Rodriguez de Fonseca,F.,
            Pintado,B., Valcarcel,J. and Gutierrez-Adan,A.
  TITLE     Impaired Spermatogenesis, Muscle, and Erythrocyte Function in U12
            Intron Splicing-Defective Zrsr1 Mutant Mice
  JOURNAL   Cell Rep 23 (1), 143-155 (2018)
   PUBMED   29617656
REFERENCE   3  (bases 1 to 3057)
  AUTHORS   Guo,G., Huss,M., Tong,G.Q., Wang,C., Li Sun,L., Clarke,N.D. and
            Robson,P.
  TITLE     Resolution of cell fate decisions revealed by single-cell gene
            expression analysis from zygote to blastocyst
  JOURNAL   Dev Cell 18 (4), 675-685 (2010)
   PUBMED   20412781
REFERENCE   4  (bases 1 to 3057)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   5  (bases 1 to 3057)
  AUTHORS   Okazaki,N., F-Kikuno,R., Ohara,R., Inamoto,S., Koseki,H.,
            Hiraoka,S., Saga,Y., Seino,S., Nishimura,M., Kaisho,T., Hoshino,K.,
            Kitamura,H., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: IV. The complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (3), 205-218 (2004)
   PUBMED   15368895
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ164719.1, AK031547.1 and AL627097.6.
            
            On Jun 7, 2018 this sequence version replaced NM_138949.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK031547.1, SRR1660811.64318.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139, SAMN01164141
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-51                CJ164719.1         2-52
            52-2472             AK031547.1         11-2431
            2473-3057           AL627097.6         106237-106821       c
FEATURES             Location/Qualifiers
     source          1..3057
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 38.68 cM"
     gene            1..3057
                     /gene="Zfp286"
                     /note="zinc finger protein 286"
                     /db_xref="GeneID:192651"
                     /db_xref="MGI:MGI:2384758"
     exon            1..93
                     /gene="Zfp286"
                     /inference="alignment:Splign:2.1.0"
     exon            94..253
                     /gene="Zfp286"
                     /inference="alignment:Splign:2.1.0"
     CDS             199..1758
                     /gene="Zfp286"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="zinc finger protein 286A isoform 1"
                     /protein_id="NP_620399.3"
                     /db_xref="CCDS:CCDS24831.1"
                     /db_xref="GeneID:192651"
                     /db_xref="MGI:MGI:2384758"
                     /translation="MEEVVIMETGLAEVPQKRALSSPDSLLSHEKSAEGDVAALRLTV
                     RSQEAMTFKDVAMDFTPEEWGKLDPAHRAVMLENYRNLVSLWLPISKPDNYNSEDGKE
                     LSKLEKSPKCSDSDMETRPESKESTSVLDFSKEESNRLTENTASDSDIETALECERWL
                     EHRQRNRERYPRQMSAHRNSLPAQEDGERDVYWKSFSQKPLLTTDDRDPKGSWDVHTL
                     GKRLKQKSKLMTKQRPYKEKKPHKCDECGELFTYRSVLIRHQRVHTGEKPYTCSECGK
                     SFSHRANLTKHQRTHTRILFECGECKKTFIESSSLEVHQRIHIGERPYECAECGKGFN
                     RSTHLAQHQLIHTGVKPYECNECDKAFIHSSALIKHQRTHTGEKPYKCQDCGKAFSHC
                     SSLTKHQRVHTGERPYECSECGKTFSQSTHLVQHQRIHTGEKPYECNECGKTFSRSSN
                     FAKHQRIHMGKKPYKCGECGKAFVHSSALIQHQRTHTGEKPFRCTECGKSFKSSPSLI
                     RHQRTHTEEQP"
     exon            254..339
                     /gene="Zfp286"
                     /inference="alignment:Splign:2.1.0"
     exon            340..454
                     /gene="Zfp286"
                     /inference="alignment:Splign:2.1.0"
     exon            455..544
                     /gene="Zfp286"
                     /inference="alignment:Splign:2.1.0"
     exon            545..3057
                     /gene="Zfp286"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1819..1824
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp286"
                     /note="hexamer: AATAGA"
     polyA_site      1839
                     /gene="Zfp286"
                     /note="major polyA site"
     regulatory      2375..2380
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp286"
                     /note="hexamer: CATAAA"
     polyA_site      2406
                     /gene="Zfp286"
     regulatory      2766..2771
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp286"
                     /note="hexamer: GATAAA"
     polyA_site      2786
                     /gene="Zfp286"
     regulatory      3036..3041
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp286"
                     /note="hexamer: AATAAA"
     polyA_site      3057
                     /gene="Zfp286"
ORIGIN      
        1 gtagttcctg gatttgccca gcaaaatgtc acgcatgcgc gactcagagc taagcggaga
       61 agttcgtagc ctttgtcagg cctgggatgg gaggtcccac gtgatctgag cgacactctc
      121 tacagagccc aagagggaag aagtccttcg aggctccgtg gactgctgac tgcgcgagaa
      181 gagcaggacc ttaggggcat ggaagaggtg gtgatcatgg agacgggttt ggccgaagtg
      241 cctcagaaaa gagctctgtc ttccccggat tctctccttt cccacgagaa gagtgcagaa
      301 ggagacgtgg ctgctctgag actcactgtc agatcccagg aagccatgac attcaaggat
      361 gtggccatgg actttacgcc agaggagtgg gggaagctgg atcctgcaca cagggccgtg
      421 atgctggaga actacaggaa cctggtctcg ctctggcttc ccatttccaa acccgataac
      481 tataattcgg aagatggaaa agaactgtcg aagcttgaga agtctcccaa gtgcagtgac
      541 tcagacatgg aaaccagacc tgagagcaag gagtcaactt cagtgctaga cttttccaaa
      601 gaagagtcaa acagactgac agaaaatact gcttctgact ccgacattga aactgctctt
      661 gaatgtgagc gttggctaga acatcgtcaa agaaatcggg agaggtaccc aagacaaatg
      721 tctgctcaca ggaactccct ccctgcgcaa gaagatggtg aacgtgatgt atattggaaa
      781 agcttcagtc agaaacctct ccttacaact gatgacagag accccaaagg atcctgggac
      841 gttcacacgc ttgggaaaag actgaagcag aaatcaaagt taatgacaaa gcagagacct
      901 tataaagaga aaaaacctca taagtgtgat gagtgtggcg aactcttcac ttaccgttcg
      961 gtacttatcc gacaccagag agttcacact ggagagaaac cttatacctg cagtgagtgc
     1021 gggaagtcct tcagccacag agccaatctg actaagcacc agagaaccca cactaggatt
     1081 ctcttcgagt gtggcgagtg caagaaaacc ttcatagaaa gttcatccct tgaggtacat
     1141 cagagaatcc acatcgggga gagaccttac gaatgcgccg agtgtgggaa aggcttcaac
     1201 cgaagtacac accttgccca gcatcagctg attcatactg gggtgaagcc ttatgaatgt
     1261 aacgaatgtg acaaagcttt cattcactca tcagctctca ttaagcatca aagaactcat
     1321 actggagaga agccctataa atgtcaagac tgtgggaaag ccttcagcca ctgctcatct
     1381 cttacgaagc accagagggt tcacacgggg gaaaggccat atgagtgcag tgagtgtggg
     1441 aagactttca gtcagagcac gcaccttgtt cagcaccaga gaatccacac tggagaaaag
     1501 ccctacgaat gtaacgaatg tgggaaaaca ttcagccgga gctcaaattt tgcaaagcat
     1561 caaagaattc acatgggaaa gaaaccctat aaatgtggag aatgtggcaa agccttcgtt
     1621 cattcgtcag ctcttattca acaccagaga actcacactg gggagaagcc tttcaggtgt
     1681 accgagtgtg ggaaaagctt caagagcagc ccctccctca tccgacatca aagaactcac
     1741 actgaagagc agccctgaga ggtgctgagt gttaggtgaa ggttggcttt attgctgcgt
     1801 ttcatatttg attgttgaaa tagagagacc ataatatgac cctggggtgt gtctgtgtgt
     1861 gtatgatttc acttgccctg tgtataactc tgaacagcag aaaggagatc ccttctaccc
     1921 attggcttga taatagtgaa gccctctggc tagagttctc aaaatttttg ttcccagttt
     1981 tccaaatgcc agattttaaa ttcaagaaat gtttgggaga cagtaaaact gtgaccattg
     2041 tgaaatctgg tttcgctgtg cttagtccca gcagggactg ctgaagcctc tcgttcagta
     2101 aggaaatctt ttgcagatta ggcttgagac atacagccgt atcctcggga agacacagct
     2161 gagttactct aaactcagag acagacaccc accatgtgta ttgtttcctt cgagagtaat
     2221 ttctgtatta aaaagtaaag gaaggttgat agatgaaaac tgcttagaat tccatccccc
     2281 acaaagagtg ctatctaact tgatgaactt aactaaatgc acttataaaa ggttctagat
     2341 tgggtttaca tgaactgtat tggtcattga ctcacataaa tggcattgct atgcttttgt
     2401 tttgaagatt ctctagttcc cttggatcta ccctacggca cctaacagat gggagtcttg
     2461 tctttctgtg ccaaggtcct cttttctcat ctttgccatc catagagccc ttggctttct
     2521 ataatcagat catcaaggag agtttatttc gatagattat tcagtgtttg gtgaagtgtg
     2581 ccctgtgaat tttagaaagc cctctgggtg tgttgcagtt tgaacatatc tgaaaggttg
     2641 ataagggtga atgtattatt tgattttggg tcccagtcaa gaacgctgaa gcaactctgt
     2701 ggcagcctgg catgctctcg agtatgtaaa aagctcacag gacagccctg aagtgactac
     2761 ccacggataa acatcttttt cctccactta cctggctttc atgcttgctc acattatttt
     2821 attattctta tcttccatac attagttggc ctttatccct gacctctaat gtaaacacac
     2881 catgaaatca tagtgatcta ttattagtag taatggatgt gaacaaaagc cattgagagg
     2941 atgggaaaca caaaacaaaa gctcaagtaa ctattgagta aaacaataca cagtgccagc
     3001 tttttattat tctattctgt attagtttat acgggaataa aattatagga aaagtaa
//
