LOCUS       NM_146224               4385 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus zinc finger protein 280D (Zfp280d), transcript variant
            1, mRNA.
ACCESSION   NM_146224
VERSION     NM_146224.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4385)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4385)
  AUTHORS   Guo,G., Huss,M., Tong,G.Q., Wang,C., Li Sun,L., Clarke,N.D. and
            Robson,P.
  TITLE     Resolution of cell fate decisions revealed by single-cell gene
            expression analysis from zygote to blastocyst
  JOURNAL   Dev Cell 18 (4), 675-685 (2010)
   PUBMED   20412781
REFERENCE   3  (bases 1 to 4385)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   4  (bases 1 to 4385)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CT025608.12, BB616601.1, BC079878.1 and AK146597.1.
            
            On Jul 24, 2015 this sequence version replaced NM_146224.4.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC079878.1, SRR9219379.10855.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849382
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-11                CT025608.12        29069-29079         c
            12-99               BB616601.1         1-88
            100-3473            BC079878.1         1-3374
            3474-3474           AK146597.1         3313-3313
            3475-4385           BC079878.1         3376-4286
FEATURES             Location/Qualifiers
     source          1..4385
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 40.08 cM"
     gene            1..4385
                     /gene="Zfp280d"
                     /gene_synonym="A930005F02Rik; Suhw4; Znf280d; ZNF634"
                     /note="zinc finger protein 280D"
                     /db_xref="GeneID:235469"
                     /db_xref="MGI:MGI:2384583"
     exon            1..142
                     /gene="Zfp280d"
                     /gene_synonym="A930005F02Rik; Suhw4; Znf280d; ZNF634"
                     /inference="alignment:Splign:2.1.0"
     exon            143..186
                     /gene="Zfp280d"
                     /gene_synonym="A930005F02Rik; Suhw4; Znf280d; ZNF634"
                     /inference="alignment:Splign:2.1.0"
     CDS             184..3108
                     /gene="Zfp280d"
                     /gene_synonym="A930005F02Rik; Suhw4; Znf280d; ZNF634"
                     /note="isoform 1 is encoded by transcript variant 1;
                     suppressor of hairy wing homolog 4"
                     /codon_start=1
                     /product="zinc finger protein 280D isoform 1"
                     /protein_id="NP_666336.3"
                     /db_xref="CCDS:CCDS40683.1"
                     /db_xref="GeneID:235469"
                     /db_xref="MGI:MGI:2384583"
                     /translation="MVTTYIKSDLQLDGRQFFQPKDNLKMAELFMECEEEELEPWQKK
                     VKEVEEDDDDEPIFVAEIASSKPAISNILNRVNPSSHSRGIKNGILNRGFTASFKPTS
                     QRCLNSASNPVAALPVNFHPESRSSDSSVIVQPFSKPGYVTNSPRVLSNNSSELLFDL
                     TQDTGLSHYQGGPTLSIAGLNETSFLSKRPSGSDISSVNPKKPKPSENTSGIDASSVI
                     SSEKSPSVISLQVVPSQGANCSSSQSKNGTTFPRACPKCDIHFNLLDPLKNHMTYCCP
                     DMINNFLGLTKADNLNSANEAKTLESEKGKLIMLVNDFYYGKHEGDVLEEQKTHTTFK
                     CFSCLKVLKNNIRFMNHMKHHLELEKQSSESWEKHTTCQHCYRQFPTPFQLQCHIEST
                     HTPHEFSTICKICELSFETEQILLQHMKDNHKPGEMPYICQVCNYRSSLFSEVESHFR
                     TSHENTKNLLCPFCLKVIKIATPYMHHYMKHQKKGIHRCTKCRLQFLTCKEKMDHKTQ
                     HHRTFVKPKQLEGLPPGTKVTIRASVGPLQSGSSVTPSISPSTSTLQLSPPEPDNVTA
                     KNHVKLTTSTPNTTISDPSKANETKSNGSKSKNKSKVSNMQKKQSTLSSSNKKSKVNT
                     ALRNLRLRRGVHECIECSSEVKDFANHFPTYVHCSFCRYNTSCSKAYVNHMMSFHSNR
                     PSKRYCIFKKHSENLRGISLVCLNCDFLTDVSGLDNMATHLSQHETHSCRVLVEQVSV
                     CIPTSERLSEIKTEAPTKGQEPVSKETARHSRAEGEPGASHSGSKQDKVPSSEEGTGC
                     DASVCEAAAATHCEKDVTVSDTENVSSSKNILSHDPDVGTDTMEKEEKTHHACQEMEL
                     KVDQSSESTNPTEAELSSETRQGLQLTSGDVGIDQFLRQGDEPKSVNSDASDPGSVRL
                     EPLTPSEVLEYEATEILHDGDDPSANTSDTVSDQTGGSPGGSNPCRAETAVDLADGEE
                     RS"
     exon            187..247
                     /gene="Zfp280d"
                     /gene_synonym="A930005F02Rik; Suhw4; Znf280d; ZNF634"
                     /inference="alignment:Splign:2.1.0"
     exon            248..394
                     /gene="Zfp280d"
                     /gene_synonym="A930005F02Rik; Suhw4; Znf280d; ZNF634"
                     /inference="alignment:Splign:2.1.0"
     exon            395..460
                     /gene="Zfp280d"
                     /gene_synonym="A930005F02Rik; Suhw4; Znf280d; ZNF634"
                     /inference="alignment:Splign:2.1.0"
     exon            461..600
                     /gene="Zfp280d"
                     /gene_synonym="A930005F02Rik; Suhw4; Znf280d; ZNF634"
                     /inference="alignment:Splign:2.1.0"
     exon            601..718
                     /gene="Zfp280d"
                     /gene_synonym="A930005F02Rik; Suhw4; Znf280d; ZNF634"
                     /inference="alignment:Splign:2.1.0"
     exon            719..889
                     /gene="Zfp280d"
                     /gene_synonym="A930005F02Rik; Suhw4; Znf280d; ZNF634"
                     /inference="alignment:Splign:2.1.0"
     exon            890..999
                     /gene="Zfp280d"
                     /gene_synonym="A930005F02Rik; Suhw4; Znf280d; ZNF634"
                     /inference="alignment:Splign:2.1.0"
     exon            1000..1223
                     /gene="Zfp280d"
                     /gene_synonym="A930005F02Rik; Suhw4; Znf280d; ZNF634"
                     /inference="alignment:Splign:2.1.0"
     exon            1224..1381
                     /gene="Zfp280d"
                     /gene_synonym="A930005F02Rik; Suhw4; Znf280d; ZNF634"
                     /inference="alignment:Splign:2.1.0"
     exon            1382..1482
                     /gene="Zfp280d"
                     /gene_synonym="A930005F02Rik; Suhw4; Znf280d; ZNF634"
                     /inference="alignment:Splign:2.1.0"
     exon            1483..1629
                     /gene="Zfp280d"
                     /gene_synonym="A930005F02Rik; Suhw4; Znf280d; ZNF634"
                     /inference="alignment:Splign:2.1.0"
     exon            1630..1764
                     /gene="Zfp280d"
                     /gene_synonym="A930005F02Rik; Suhw4; Znf280d; ZNF634"
                     /inference="alignment:Splign:2.1.0"
     exon            1765..2072
                     /gene="Zfp280d"
                     /gene_synonym="A930005F02Rik; Suhw4; Znf280d; ZNF634"
                     /inference="alignment:Splign:2.1.0"
     exon            2073..2213
                     /gene="Zfp280d"
                     /gene_synonym="A930005F02Rik; Suhw4; Znf280d; ZNF634"
                     /inference="alignment:Splign:2.1.0"
     exon            2214..2276
                     /gene="Zfp280d"
                     /gene_synonym="A930005F02Rik; Suhw4; Znf280d; ZNF634"
                     /inference="alignment:Splign:2.1.0"
     exon            2277..2395
                     /gene="Zfp280d"
                     /gene_synonym="A930005F02Rik; Suhw4; Znf280d; ZNF634"
                     /inference="alignment:Splign:2.1.0"
     exon            2396..2432
                     /gene="Zfp280d"
                     /gene_synonym="A930005F02Rik; Suhw4; Znf280d; ZNF634"
                     /inference="alignment:Splign:2.1.0"
     exon            2433..2478
                     /gene="Zfp280d"
                     /gene_synonym="A930005F02Rik; Suhw4; Znf280d; ZNF634"
                     /inference="alignment:Splign:2.1.0"
     exon            2479..2534
                     /gene="Zfp280d"
                     /gene_synonym="A930005F02Rik; Suhw4; Znf280d; ZNF634"
                     /inference="alignment:Splign:2.1.0"
     exon            2535..4372
                     /gene="Zfp280d"
                     /gene_synonym="A930005F02Rik; Suhw4; Znf280d; ZNF634"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4345..4350
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp280d"
                     /gene_synonym="A930005F02Rik; Suhw4; Znf280d; ZNF634"
                     /note="hexamer: AATAAA"
     polyA_site      4372
                     /gene="Zfp280d"
                     /gene_synonym="A930005F02Rik; Suhw4; Znf280d; ZNF634"
                     /note="major polyA site"
ORIGIN      
        1 tcccccctca cggcgcccag cagccccgct ccgcgatggg agccggagcg gcctcggcgt
       61 acacagcccg cgctcctccc tcgcctcctc ctctttctcc tcctcctcag ggctccagtc
      121 aggccgagcc gctccgctca cgaaaggcaa gctgagatac aacttgctgc tttttgtggt
      181 cacatggtga caacatatat aaagtcagat ctgcaacttg atgggagaca gttctttcaa
      241 ccaaaagata atttaaaaat ggcagaactc tttatggaat gtgaagaaga ggagctagag
      301 ccatggcaga agaaagtgaa agaagtcgaa gaggatgatg atgatgagcc catctttgtt
      361 gcagagatag caagttcaaa gccagctatt tcaaatattt tgaacagagt taaccccagc
      421 tctcattcaa gaggaataaa gaatggtata ctcaatcgag gttttactgc ttcattcaag
      481 cctacaagtc aacgctgcct gaattcagca tcaaatcctg tggctgcctt gccagtaaat
      541 tttcatcctg aatctagatc ttcagatagc tctgttattg ttcagccatt ttctaaacct
      601 ggttatgtaa caaattcacc aagagttctg tctaataact cttcagagtt actgtttgac
      661 ttgacccagg atacaggatt atcacattac caggggggac cgacactttc tattgcaggt
      721 ttgaatgaaa cttcattttt atcaaaacgt ccttctggtt ctgacataag cagtgttaac
      781 ccaaaaaagc ctaaacccag tgaaaatact tctggaatag atgcctcttc tgtaatctct
      841 tcagaaaagt ccccatcagt gatatctctc caagtggtgc catcgcaagg tgcaaattgt
      901 tcatcaagtc aatctaaaaa tggaacaact tttccaagag catgtcccaa gtgtgatatt
      961 cacttcaatc ttttggatcc tctaaaaaat cacatgacgt attgttgtcc agacatgata
     1021 aataactttt tgggattgac taaagcagac aatttaaatt cagcaaatga agctaagact
     1081 cttgaatcag agaaaggaaa attgataatg ttagttaatg acttttatta cggaaaacat
     1141 gaaggagacg tcctggaaga acagaagact catacaacct ttaagtgctt cagttgctta
     1201 aaagttctca aaaataatat taggtttatg aaccacatga agcaccattt ggagctcgag
     1261 aagcagagca gcgagagctg ggagaagcac accacgtgcc agcactgcta ccggcagttc
     1321 cccacgccct tccagctcca gtgccacatc gagagcaccc acactcctca tgagttctcc
     1381 accatttgta agatctgtga gctatcattt gaaactgaac agattctctt acaacatatg
     1441 aaggataacc ataagcctgg tgaaatgcca tacatctgcc aggtttgcaa ttacagatca
     1501 tcattatttt ctgaggtaga gtctcatttt agaacatcac atgaaaacac taagaatttg
     1561 ctatgtccat tctgcctcaa agttattaaa atcgccacgc cctatatgca tcattacatg
     1621 aagcatcaga aaaagggaat acatcgttgc accaaatgca gactgcagtt tttgacatgc
     1681 aaggaaaaaa tggatcacaa gactcaacat caccgaacat ttgtaaaacc caagcaactg
     1741 gaaggacttc cccctggaac aaaagttact attcgagctt cagttggacc tcttcagtca
     1801 ggatcttcag ttacaccttc tatcagccca agcacttcta ccctccagct ctcacctcca
     1861 gagcctgaca atgtaactgc taaaaatcac gtgaagttga ctacaagtac accaaacaca
     1921 accatatctg accccagtaa agctaatgag accaagtcta atggcagtaa atctaaaaac
     1981 aagtcaaaag tctccaacat gcagaagaaa caaagcacat tgtctagtag taataaaaaa
     2041 agcaaagtaa acacagcact aaggaactta aggttacgtc ggggtgttca cgagtgtatt
     2101 gagtgttctt ctgaagtaaa agattttgca aaccattttc ctacatatgt ccactgtagt
     2161 ttttgcagat ataacactag ctgtagcaaa gcctatgtaa atcatatgat gagctttcat
     2221 agtaaccgtc caagtaaaag atactgtata tttaagaagc attcagaaaa tctcaggggc
     2281 atttctctag tgtgccttaa ttgtgatttc ctaactgacg tttctggctt agataatatg
     2341 gctacacact taagtcagca tgaaactcat tcttgccgag ttctagtaga gcaagtttct
     2401 gtttgtatcc caacttctga acgtctttct gaaataaaaa ctgaagctcc cactaaggga
     2461 caagaacctg tgtctaagga aacagcaaga catagtagag ctgaaggaga gccaggagca
     2521 tcacattctg gaagtaagca ggataaagtt ccttcatcag aagaaggcac tgggtgtgat
     2581 gcaagtgtat gtgaagctgc agcagcaaca cactgtgaaa aagatgtaac ggtttcagat
     2641 acagaaaatg taagcagctc aaagaacatc ttgagtcatg atccagatgt tggaacagat
     2701 actatggaaa aggaagaaaa aacacatcat gcttgtcagg aaatggagct gaaggtggac
     2761 cagagttcag aaagcacaaa tcccactgaa gctgaactgt cttcagagac tcgtcaaggt
     2821 ttgcagttaa catcagggga tgttggcatt gatcaatttc tgaggcaagg agatgaacct
     2881 aaatctgtga attctgatgc tagtgaccca ggcagtgttc gtttggaacc tttgacgcca
     2941 tcagaagtac ttgagtatga agccacagag atcctccacg acggtgatga tccttcagct
     3001 aacaccagtg acacggtatc tgatcaaaca ggtggcagtc ctggaggaag taacccttgt
     3061 agagcagaga cagcagtaga cctggcagat ggagaggaaa gaagctgaag tgacatagtc
     3121 atttcaagtt tcattcccaa cagcacttag aacaatagtg tctggtgagc tcaggagtgc
     3181 cgtggtaaag ggcagccgag ggagatctga ggaggtctgt catacacttc acctgtgtgt
     3241 tcaatcttat taaatcagtt taccagtaat agcatggtta gtatgaattt ccacatttaa
     3301 aaaaacctga atagaacttt agtgaaaact aagtttgtca tccaaaggtc tcttagcact
     3361 ttttgataaa atcttgttta ccaatatgaa attattataa tactaattgc tatgttcatc
     3421 agacttttcc aactttcatt agtactaaaa gtcctcatca cctgaatatt tcttttagta
     3481 aacttaaagg aagagattta aaaccatgca ttttttaaaa atacctttaa actgcctatc
     3541 aactgttact gttaatgaag actttgtttt tactatgatc ctggtgataa agcatgctta
     3601 gagtgctaaa ttggcctgtt gagaacttgg atgaatataa aaattaagtt tggatttaat
     3661 ataacattcc aatctgtcag aagcatgcaa acagaatttt agaatctgtg cacctccata
     3721 caagtgttag cctgccaggc tgtcagctta cctttattaa actttcagtg aaagtgaaat
     3781 tatgaaaata taagtttata tttgtgcttt tagtcagtgt ataagctgtg cagaacccca
     3841 cctcagcccc catgaactag ttgtataaag tagaaatctg ttattgaagc tcttaaatag
     3901 ctactatgct tttaatatta tttcaatgat ttttagcaat agacccataa aaatggtctg
     3961 gaaaccaaac caaagtatgg tagaatgtag gcaaaaagaa ttgacctaaa aacatgcctc
     4021 cgcatgtact caactatgtt aagggacttc cttaattgta aaagttgaaa cttcaaatgg
     4081 gaccctaaag catatgttta aaaacaaaaa aaaaaaagtt tgtggaaatt agcctaattt
     4141 atcagctatt aagttgattt ttagatatag aaatgaatat aacaaacaat ttcattttaa
     4201 gtactaataa aattttattt taaatgctgc atttttaatt cttaagatgt actttgaatt
     4261 cttaaactgt ctaattgaat gttaaacgtt ttcaaggcct gttaaaattc tgttgtatat
     4321 agtagttttt gagcagatat ttgcaataaa aacctgtctt tgaataattt taaaaaaaaa
     4381 aaaaa
//
