LOCUS       NM_153532               4791 bp    mRNA    linear   ROD 17-JUL-2024
DEFINITION  Mus musculus zinc finger protein 280C (Zfp280c), transcript variant
            1, mRNA.
ACCESSION   NM_153532 XM_984709 XM_984744
VERSION     NM_153532.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4791)
  AUTHORS   Ying,Y., Wang,M., Chen,Y., Li,M., Ma,C., Zhang,J., Huang,X.,
            Jia,M., Zeng,J., Wang,Y., Li,L., Wang,X., Tao,Q. and Shu,X.S.
  TITLE     Zinc finger protein 280C contributes to colorectal tumorigenesis by
            maintaining epigenetic repression at H3K27me3-marked loci
  JOURNAL   Proc Natl Acad Sci U S A 119 (22), e2120633119 (2022)
   PUBMED   35605119
REFERENCE   2  (bases 1 to 4791)
  AUTHORS   Guo,G., Huss,M., Tong,G.Q., Wang,C., Li Sun,L., Clarke,N.D. and
            Robson,P.
  TITLE     Resolution of cell fate decisions revealed by single-cell gene
            expression analysis from zygote to blastocyst
  JOURNAL   Dev Cell 18 (4), 675-685 (2010)
   PUBMED   20412781
REFERENCE   3  (bases 1 to 4791)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: III. the complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (4), 167-180 (2003)
   PUBMED   14621295
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL669901.26, AK141491.1 and AI481209.1.
            
            On Dec 9, 2017 this sequence version replaced NM_153532.3.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and it encodes the longest protein (isoform 1). Variants
            1 and 2 encode the same protein.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC063775.1, SRR9219380.63921.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164138
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-886               AL669901.26        163091-163976       c
            887-3962            AK141491.1         132-3207
            3963-4754           AL669901.26        113069-113860       c
            4755-4791           AI481209.1         1-37                c
FEATURES             Location/Qualifiers
     source          1..4791
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 25.68 cM"
     gene            1..4791
                     /gene="Zfp280c"
                     /gene_synonym="mKIAA1584; Suhw3; Zfp633; Znf280c"
                     /note="zinc finger protein 280C"
                     /db_xref="GeneID:208968"
                     /db_xref="MGI:MGI:2387585"
     exon            1..886
                     /gene="Zfp280c"
                     /gene_synonym="mKIAA1584; Suhw3; Zfp633; Znf280c"
                     /inference="alignment:Splign:2.1.0"
     exon            887..933
                     /gene="Zfp280c"
                     /gene_synonym="mKIAA1584; Suhw3; Zfp633; Znf280c"
                     /inference="alignment:Splign:2.1.0"
     CDS             903..3131
                     /gene="Zfp280c"
                     /gene_synonym="mKIAA1584; Suhw3; Zfp633; Znf280c"
                     /note="isoform 1 is encoded by transcript variant 1;
                     suppressor of hairy wing homolog 3"
                     /codon_start=1
                     /product="zinc finger protein 280C isoform 1"
                     /protein_id="NP_705760.2"
                     /db_xref="CCDS:CCDS30111.1"
                     /db_xref="GeneID:208968"
                     /db_xref="MGI:MGI:2387585"
                     /translation="MDKDNSVQEKGLFLSSWKLDNSKMAELFMECEEEELEPWQQKVE
                     ESQSKDDDDELIFVGEISSSKPAISNILNRCSPGSSSKGLKNGSFNPAISNIFKPTSQ
                     HYRNPSSNALVALPSFHPALKSSESSDGQTVSKLDFTKTSPQEDSGACSVSQSDSTQD
                     IPSSNILQPRTGVDQTLGLKHPSTSKVNSVNPKKPKTSASISETRPCSSSSSQTAPSG
                     ASSQTVLSNVNTSSVQSAPGSSSLRSCPKCNVKFRLLDPLKCHMKRCCPDMINKFLET
                     LKSENSKAVSKATTDSDKEKLIMLVSDFYYGRHEGTIEESQKTHTTFKCFSCTKVLKN
                     NIRFMNHMKHHLELEKQNNETWESHTTCQHCYRQYPNPFQLQCHIESTHTPHDFSTIC
                     KICELSFETEHMLLQHMKDTHKPGEMPYICQVCQFRSSIFSDVETHFRSSHENTKNLL
                     CPFCLKVSRMATPYMNHYMRHQKKGIYRCPKCRLQFLTSKEKTEHKLEHRTFIKPKEL
                     EGLPPGTKVIIRASLGSSQSRASSPPSSTIPSTSLQLSVPKSKSTTTKNNSKVSANKA
                     TTTSPQTVATTTGKPSASKPGTGTTKSKAKPSYKQKRQRTRKNKFSIDLKNLRCHQGS
                     HMCIECRSKIKDFSSHFSTHINCDFCKYTTNCNKAFTNHMSSHNDHPSKQLYIFKKQS
                     RARRGITLVCLKCDFLADTSGLDRMAKHLNQRKTHTCQVVIENVTERAVTSESASDGL
                     FK"
     exon            934..1110
                     /gene="Zfp280c"
                     /gene_synonym="mKIAA1584; Suhw3; Zfp633; Znf280c"
                     /inference="alignment:Splign:2.1.0"
     exon            1111..1176
                     /gene="Zfp280c"
                     /gene_synonym="mKIAA1584; Suhw3; Zfp633; Znf280c"
                     /inference="alignment:Splign:2.1.0"
     exon            1177..1310
                     /gene="Zfp280c"
                     /gene_synonym="mKIAA1584; Suhw3; Zfp633; Znf280c"
                     /inference="alignment:Splign:2.1.0"
     exon            1311..1416
                     /gene="Zfp280c"
                     /gene_synonym="mKIAA1584; Suhw3; Zfp633; Znf280c"
                     /inference="alignment:Splign:2.1.0"
     exon            1417..1581
                     /gene="Zfp280c"
                     /gene_synonym="mKIAA1584; Suhw3; Zfp633; Znf280c"
                     /inference="alignment:Splign:2.1.0"
     exon            1582..1691
                     /gene="Zfp280c"
                     /gene_synonym="mKIAA1584; Suhw3; Zfp633; Znf280c"
                     /inference="alignment:Splign:2.1.0"
     exon            1692..1912
                     /gene="Zfp280c"
                     /gene_synonym="mKIAA1584; Suhw3; Zfp633; Znf280c"
                     /inference="alignment:Splign:2.1.0"
     exon            1913..2070
                     /gene="Zfp280c"
                     /gene_synonym="mKIAA1584; Suhw3; Zfp633; Znf280c"
                     /inference="alignment:Splign:2.1.0"
     exon            2071..2171
                     /gene="Zfp280c"
                     /gene_synonym="mKIAA1584; Suhw3; Zfp633; Znf280c"
                     /inference="alignment:Splign:2.1.0"
     exon            2172..2318
                     /gene="Zfp280c"
                     /gene_synonym="mKIAA1584; Suhw3; Zfp633; Znf280c"
                     /inference="alignment:Splign:2.1.0"
     exon            2319..2450
                     /gene="Zfp280c"
                     /gene_synonym="mKIAA1584; Suhw3; Zfp633; Znf280c"
                     /inference="alignment:Splign:2.1.0"
     exon            2451..2758
                     /gene="Zfp280c"
                     /gene_synonym="mKIAA1584; Suhw3; Zfp633; Znf280c"
                     /inference="alignment:Splign:2.1.0"
     exon            2759..2896
                     /gene="Zfp280c"
                     /gene_synonym="mKIAA1584; Suhw3; Zfp633; Znf280c"
                     /inference="alignment:Splign:2.1.0"
     exon            2897..2959
                     /gene="Zfp280c"
                     /gene_synonym="mKIAA1584; Suhw3; Zfp633; Znf280c"
                     /inference="alignment:Splign:2.1.0"
     exon            2960..3078
                     /gene="Zfp280c"
                     /gene_synonym="mKIAA1584; Suhw3; Zfp633; Znf280c"
                     /inference="alignment:Splign:2.1.0"
     exon            3079..3115
                     /gene="Zfp280c"
                     /gene_synonym="mKIAA1584; Suhw3; Zfp633; Znf280c"
                     /inference="alignment:Splign:2.1.0"
     exon            3116..4779
                     /gene="Zfp280c"
                     /gene_synonym="mKIAA1584; Suhw3; Zfp633; Znf280c"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4712..4717
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp280c"
                     /gene_synonym="mKIAA1584; Suhw3; Zfp633; Znf280c"
                     /note="hexamer: AATAAA"
     polyA_site      4732
                     /gene="Zfp280c"
                     /gene_synonym="mKIAA1584; Suhw3; Zfp633; Znf280c"
                     /note="major polyA site"
     regulatory      4758..4763
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp280c"
                     /gene_synonym="mKIAA1584; Suhw3; Zfp633; Znf280c"
                     /note="hexamer: AATAAA"
     polyA_site      4779
                     /gene="Zfp280c"
                     /gene_synonym="mKIAA1584; Suhw3; Zfp633; Znf280c"
                     /note="major polyA site"
ORIGIN      
        1 ctccctgagg gaggactcca gtttcttgag ggttaaatgc atcttaaaac cagttcatac
       61 gccagtactt tctagctttt gcctaaggtt caattcatta aataatgcct catttatttt
      121 ataggcatgt cgaagttcca gagaaagaaa agcaaggagg tttgcctaaa atttttaaga
      181 agtgttactc aattcccatc tctacattta aaaaaaatca ttttcctatt ttttaatact
      241 tattatatat acagcatccg aactgcatat atgcctgcag gccaaaagat ggcatcggat
      301 cccattacag atggttatga gccaccatgt ggttgctggg aactgaactc aggacctctg
      361 gaagagcatc ttgagttctg gaagagccac atgtgctgag ccatctctcc agcctcttgt
      421 cgctacagtt tttaaagatg ttatattgtt tgtacatttt agcatttgaa taatactata
      481 tccaagtacg tttaaaagct gaagaagagc attggaaaaa gtactgataa tgaagaactg
      541 ccaacctcag cttttcctat ttaatccctt tgctccagtt tcctaaaatt cccaatatag
      601 gctggccttt tcagcccagc gtttcgccac ttaacattac ctttttatga agggaaggga
      661 ttctacgcct tcctattctt ccacttattt tatttttcta ggagaacact tagaaccata
      721 cagaattttt ggaagtacta gggatcaatt tgtatatatt aattatagct gaataatttt
      781 tttctttctg ttttcaggga ggactttgtc tttctggagc caggaaggtg atgtaattgc
      841 taccaccaaa cctgagaact tgagctcaat cgcaaggacc catatgttgg ttcttcaatt
      901 tgatggataa agataactct gttcaagaaa aagggttgtt tctctcctct tggaaattag
      961 ataattcaaa aatggctgaa cttttcatgg aatgtgaaga agaagagttg gaaccatggc
     1021 agcagaaagt agaagaaagt caaagtaaag acgacgatga tgagctgatc tttgttggag
     1081 agatatcaag ttccaagcca gccatttcca atattttgaa cagatgtagc cctggttcat
     1141 cttcaaaggg actaaagaac ggttcattca atccagctat ttctaatata ttcaagccta
     1201 cgagtcaaca ctacagaaat ccatcatcga atgcactggt tgctttgcca agctttcatc
     1261 ctgctctcaa atcttcagag agttctgatg gtcagactgt gtctaaactt gactttacca
     1321 agacttcacc ccaagaggat tccggtgctt gttcggtctc acagtcagac tcgacccaag
     1381 atataccgtc ttccaacata ctgcaaccga ggacaggtgt cgatcaaact ttaggattaa
     1441 aacatccttc cacttccaaa gtaaacagtg ttaatccaaa aaagccaaag acgagtgcga
     1501 gcatttctga aacacgccct tgctcttcat catcttcaca gacggcgcct tcaggggctt
     1561 cttcccaaac tgtactatca aatgtgaata cctcatcagt tcagtctgca cctggatcat
     1621 cttcactaag atcttgtcca aagtgcaatg ttaagttccg acttctggat cctttgaagt
     1681 gccacatgaa gcgttgctgc ccagacatga taaataagtt tctggaaact ctcaagtcag
     1741 aaaattcaaa ggctgtaagc aaagctacca ctgactcaga taaagaaaaa ctgatcatgc
     1801 ttgtcagtga tttttattat ggaagacatg aaggaactat tgaggaaagc cagaagactc
     1861 acaccacttt taaatgtttc agttgcacaa aagttctcaa aaataatatt aggttcatga
     1921 accacatgaa acaccacttg gaacttgaaa agcagaacaa cgagacctgg gaaagccata
     1981 ctacatgcca acactgctac cggcagtacc ccaacccctt ccagctccag tgccacattg
     2041 agagtacaca tactcctcat gatttttcta ctatttgcaa gatctgtgaa ttgtcatttg
     2101 aaacagagca tatgctttta caacacatga aggatactca taaacctggt gaaatgccat
     2161 atatttgcca ggtttgccag tttagatcat caatattttc tgatgtagaa actcacttca
     2221 gatcatctca tgaaaacact aagaacttgc tatgtccgtt ttgcctcaaa gttagtagaa
     2281 tggcaacccc ttatatgaat cactacatga gacatcagaa aaaaggaatt tatcgttgcc
     2341 cgaaatgcag actacaattt ttgacctcca aggagaaaac agaacataag ttagaacatc
     2401 gcacatttat aaagcctaaa gaactagagg gattgcctcc tgggacaaaa gttattattc
     2461 gagcttcatt aggatctagt cagtcaagag cctcaagccc accttctagt accatcccaa
     2521 gcacttctct tcagctctca gttccaaagt ctaaaagtac aactactaag aataactcaa
     2581 aagtatctgc aaataaagct accaccacta gccctcaaac agttgcaacc acaactggta
     2641 agcccagtgc aagtaagcca ggtacgggga caactaaatc caaagccaag ccctcctaca
     2701 agcaaaagag acaacgcacc aggaaaaaca aattcagcat agatctgaag aacttaaggt
     2761 gtcaccaggg aagtcacatg tgtattgagt gccgttccaa aataaaagat ttttcaagcc
     2821 acttttctac acatataaat tgtgattttt gcaagtatac cactaactgt aacaaagcct
     2881 ttacaaatca tatgagctct cacaatgacc acccaagtaa gcagctttat atttttaaga
     2941 agcaatcacg agctcgcagg ggcatcactc tagtgtgcct taaatgtgac ttcctagccg
     3001 atacttctgg cttagaccgt atggctaaac acttaaatca acgtaaaact catacttgcc
     3061 aagttgtaat agagaatgtt accgaaagag ccgtaacttc tgaatccgct tctgatggct
     3121 tgttcaaata gattcctgct ctatgaagct tgtgcaacct ggtgcaagac aaggtggaat
     3181 ttcctaagtt caaagatctg cagtgttttc atgaaggcag ttacaattca caacactagc
     3241 tcgcattatc cagctctttc cagctttcag atgctgggag attcttattc catcttctct
     3301 gtgtcaggtt aacatgtgtt agcatgtgct ttgattctcc agttgatgct ggagaaggca
     3361 ccttagttgc tgtagtctat tcttgttttg tttcagataa tttgtatttt tctttgttgt
     3421 acttgccttc tgaatatttt gtgtcaaatg gtatagctgc tgttttgtct gttttgcctg
     3481 cttcttaatt tcttatcagt cttggtggtc ggatagctgt tttttccttc attctttgta
     3541 tgtcattggt ctatttgtca gatgcaaagg caacacagat atttcaaaaa aaatgtccag
     3601 tgtactccgg gacagtgttc ccattcaatg aagacaactg atgactagtc tctctttcca
     3661 aggaatatga tttatttcac tgggagacct gcttcagtgt gtggccttag gattttatca
     3721 gttcttaggc agagtccctt cctacctgac tggccttccg taaggctgat agtatctggc
     3781 caccgatgcc tgcaaggtgc accaaataga tttgagcaca acttccctct gaggactttg
     3841 gttcttaagt gtaagcttat gagtttgtac taattatgaa agcccatcaa gtgagtgaag
     3901 cttacattca tgtttttgga aaaacaaact ttgtgaagtt atggctccaa agtaacagtt
     3961 atttatgtta tcatttaaag ttttagccaa cattccacga gttctcgact tattctagtg
     4021 gttaataact tttgaaaatt taaatgttaa tagcttaatt tttgtcattc cccaaactta
     4081 ttatctacat ttgtaatttc tgcttaattc tttttttgtg tgtttgctta aaatgccaag
     4141 aaatttcttt aaaactctct acctatttca tacagctacc tactgttagt ttctcttttt
     4201 ttcttttctt tttttgtttt tgtttggttt gtttaatttt tttgaggcat ggtttctatt
     4261 atatagccct ggctatcctg atgctcacta tggagatcag gctgaccttg gactcataga
     4321 tttctgcctg cctcttcttc ccaagtgcta aatttaaagg catgagtgtt acctgttcag
     4381 ttcattagac attaatatat gttctctcta tcttgggact atcataacat cttagtggtc
     4441 aggaaatgaa gacaaagaac aaaaactccg cttacagatc ttaaaagaag ttttaagtta
     4501 cattgctatt aacttagtaa ttatctcctt agccattaat gtaattcctt agataaatat
     4561 aatatattca aaaatattgg gaccaaaaat gcacttgttt cttgcccaca tatatagaga
     4621 gagatgtata tttttttatt ttggtgtttg tttattttgg ttacatcgaa tatagatttt
     4681 gctgaacagt tttgatgtta cttatttttt taataaaatt tgtattgtta aacactcttg
     4741 ggaattattt tataataaat aaattgatat aaaaacctaa aaaaaaaaaa a
//
