LOCUS       NM_001082485            6305 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus zinc finger protein 266 (Zfp266), transcript variant
            1, mRNA.
ACCESSION   NM_001082485 XM_001475072 XM_920572
VERSION     NM_001082485.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6305)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 6305)
  AUTHORS   Kaemena,D.F., Yoshihara,M., Beniazza,M., Ashmore,J., Zhao,S.,
            Bertenstam,M., Olariu,V., Katayama,S., Okita,K., Tomlinson,S.R.,
            Yusa,K. and Kaji,K.
  TITLE     B1 SINE-binding ZFP266 impedes mouse iPSC generation through
            suppression of chromatin opening mediated by reprogramming factors
  JOURNAL   Nat Commun 14 (1), 488 (2023)
   PUBMED   36717582
  REMARK    GeneRIF: B1 SINE-binding ZFP266 impedes mouse iPSC generation
            through suppression of chromatin opening mediated by reprogramming
            factors.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 6305)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 6305)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. PMID: 29144450]
REFERENCE   5  (bases 1 to 6305)
  AUTHORS   Bulfone,A., Carotenuto,P., Faedo,A., Aglio,V., Garzia,L.,
            Bello,A.M., Basile,A., Andre,A., Cocchia,M., Guardiola,O.,
            Ballabio,A., Rubenstein,J.L. and Zollo,M.
  TITLE     Telencephalic embryonic subtractive sequences: a unique collection
            of neurodevelopmental genes
  JOURNAL   J Neurosci 25 (33), 7586-7600 (2005)
   PUBMED   16107646
REFERENCE   6  (bases 1 to 6305)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ053742.1, BC089552.1, AC171206.2 and BM941296.1.
            
            On or before Sep 19, 2008 this sequence version replaced
            XM_920572.2, XM_001475072.1.
            
            Transcript Variant: This variant (1) represents the longer
            transcript. Variants 1 and 2 encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR9219382.74857.1,
                                           SRR9219380.83063.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164133 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2                 CJ053742.1         2-3
            3-1677              BC089552.1         2-1676
            1678-6083           AC171206.2         128546-132951       c
            6084-6305           BM941296.1         177-398
FEATURES             Location/Qualifiers
     source          1..6305
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 7.56 cM"
     gene            1..6305
                     /gene="Zfp266"
                     /gene_synonym="5330440G10Rik; 5730601F06Rik"
                     /note="zinc finger protein 266"
                     /db_xref="GeneID:77519"
                     /db_xref="MGI:MGI:1924769"
     exon            1..76
                     /gene="Zfp266"
                     /gene_synonym="5330440G10Rik; 5730601F06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            77..176
                     /gene="Zfp266"
                     /gene_synonym="5330440G10Rik; 5730601F06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            177..343
                     /gene="Zfp266"
                     /gene_synonym="5330440G10Rik; 5730601F06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            344..498
                     /gene="Zfp266"
                     /gene_synonym="5330440G10Rik; 5730601F06Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             474..2288
                     /gene="Zfp266"
                     /gene_synonym="5330440G10Rik; 5730601F06Rik"
                     /codon_start=1
                     /product="zinc finger protein 561"
                     /protein_id="NP_001075954.1"
                     /db_xref="CCDS:CCDS52732.1"
                     /db_xref="GeneID:77519"
                     /db_xref="MGI:MGI:1924769"
                     /translation="MAAIDLSHGLLSREPIYVYEANIEVDGTVTDNQANCYQDSVTFD
                     DVAVEFTPDEWTLLDLTQKNLYREVMLENYENLTSVGCQLFIPSLTPWLKQEESEVAE
                     SAVPQQLELQPTIDDSELENYFRMQSSSATEMVGDSSLHEQSGNHNEEDLCDSKPCGN
                     VLGEQLCLNTEVSMQSQGYSSECNWYGKDILSLLKETSTGQTVSELNQCGKLFSLTPN
                     IMYPSTSTNEKPFECTDCETAFFNQSYFQPDMRPHNGGEPFDWSKYGNGFIHPTGLAM
                     HLPILNARNPYKFEECGKDFQYFACLNNPMGMCTGEKFCDCKECWKAFTVSSHLTQYV
                     SIHTEEKSKVCKICGKSFANYSRLSAHVKTHNEEKPFVCKECGKAFKNMSYLNDHVRI
                     HTGIKSYKCMECGKAFLRWSGLTEHIRVHTGEKPYECKECGKTFSRSTQLTEHIRTHT
                     GIKPYECKECGKAFTQYSGLATHVRIHSGEKPFACKECGKAFTRTSGLIHHVRTHTGE
                     KPFECVHCGKTFITSSHRTKHLKIHSGEKPFVCNICGKAFIYSTSLNIHMRTHTGEKP
                     YICKQCGKAFAVYSRLRKHSRVHTEEKPYQCEGMAVAI"
     exon            499..587
                     /gene="Zfp266"
                     /gene_synonym="5330440G10Rik; 5730601F06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            588..714
                     /gene="Zfp266"
                     /gene_synonym="5330440G10Rik; 5730601F06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            715..795
                     /gene="Zfp266"
                     /gene_synonym="5330440G10Rik; 5730601F06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            796..875
                     /gene="Zfp266"
                     /gene_synonym="5330440G10Rik; 5730601F06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            876..6285
                     /gene="Zfp266"
                     /gene_synonym="5330440G10Rik; 5730601F06Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6263..6268
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp266"
                     /gene_synonym="5330440G10Rik; 5730601F06Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      6285
                     /gene="Zfp266"
                     /gene_synonym="5330440G10Rik; 5730601F06Rik"
                     /note="major polyA site"
ORIGIN      
        1 cccccttttc tccgagctct gagtccttct cggcgtttgt ccgagggctc tccacgcagc
       61 gctcggtgag gattcgaaag aatagacttt tcgccattgg tatcacattg agacgctgca
      121 ttttccattc ttggaccggg cgattctgtt tgggggagcc gagctttggc tgaaaggact
      181 tctagatctg tacagaacag gatattttct gtgtccttcc ctgctctgct catgcctacc
      241 acaggaatag gacttcctaa taatttgctg aaagaattaa agaataagcc agacctgaaa
      301 taaaccagta cctccagtac ctccaataaa tgaaatagaa gaggactcca tataaccctg
      361 tattaagagg aatggagatt gcctctgtcc acttagattc ataagctgtc ccgaagtgat
      421 cttggcatca gggaagggag tgttcaggca catttcacca tcagcatcac gggatggcag
      481 ccattgattt gtcccatggc cttctttcta gagagcctat ctacgtctac gaagcaaaca
      541 tagaggtaga cgggacggtg actgacaacc aggcaaattg ttaccaggat tcagtgacct
      601 tcgatgatgt ggctgtggag ttcaccccgg atgagtggac tttactggac ctgactcaga
      661 agaatctata ccgagaggtc atgctggaga actacgagaa cttgacttca gtaggatgtc
      721 agttattcat tcctagtctg accccctggt taaaacaaga agagtccgag gtggcggaaa
      781 gtgctgttcc tcaacaattg gaactacaac ctacaattga cgattcagag cttgagaatt
      841 attttaggat gcaaagttcc agtgcaacag aaatggtggg tgactcatct cttcacgagc
      901 agtcaggaaa ccacaatgaa gaggacctat gtgactctaa gccatgtggg aatgtgttgg
      961 gtgaacaatt atgccttaac acagaggtga gcatgcaaag tcaaggatac agttctgagt
     1021 gtaactggta tgggaaagac attctttctt tgctcaagga aacctctact ggacagaccg
     1081 tttctgagct taatcagtgt ggaaaactct tcagtctgac tccaaacatc atgtacccga
     1141 gcactagcac aaatgagaag ccctttgaat gcacagactg tgagacagcc ttttttaatc
     1201 agtcttactt tcagccagat atgaggcctc acaatggagg agaacccttt gactggagta
     1261 aatacgggaa tggttttatt catcctacag gccttgctat gcatcttcca attctcaatg
     1321 caagaaaccc ctacaaattt gaggaatgtg gaaaggactt tcagtatttt gcatgcctta
     1381 ataatcccat gggaatgtgc actggagaaa aattctgtga ctgcaaggaa tgttggaaag
     1441 ccttcacggt ttcctcacac ctaactcaat atgtatcaat tcatactgaa gaaaaatcca
     1501 aagtatgtaa gatatgtggg aagtcctttg ctaactattc tcgactttct gcacatgtaa
     1561 aaactcataa tgaagaaaag ccctttgtat gtaaggagtg tggaaaggcc tttaaaaata
     1621 tgtcatacct taatgatcac gttagaattc acactggaat aaaatcatac aaatgtatgg
     1681 aatgtgggaa agccttcctt cgatggtcag gccttactga acacataaga gttcacactg
     1741 gggaaaagcc ttacgaatgt aaggaatgtg gaaaaacctt ttctagatct actcagctta
     1801 ctgaacacat aagaacacac actggaatca aaccttatga atgtaaggaa tgtgggaaag
     1861 cctttactca gtactcgggc cttgccaccc atgtacgaat tcatagtgga gaaaagccct
     1921 ttgcttgtaa ggagtgtggg aaggccttta ccaggacctc tggcctgatt catcatgtga
     1981 gaactcacac aggagagaag ccttttgaat gtgttcattg tgggaaaacc ttcattactt
     2041 cctcccatcg cactaaacat ctgaaaattc acagtggcga aaagcccttt gtgtgtaaca
     2101 tatgtgggaa agcatttata tattctacat cccttaacat tcacatgcga acccacactg
     2161 gagagaagcc ctatatatgt aagcagtgtg ggaaagcctt cgctgtttac tcacgactga
     2221 ggaaacacag cagagttcac actgaggaga agccctatca atgtgagggt atggccgttg
     2281 ctatttagcc tatctgttgc cacctttaaa tattgacagt gacaccaaag atcatcagat
     2341 tagtcttaac tgctttgtgt gggttataga ggctcacact ggccttagac accatccgaa
     2401 ttttatgaaa taggatattt aggtgccccc ccaacttttc ttcttttggg tagtgctgag
     2461 gattgaccta gaacatcatg caagctaggc aagcactcag ttactgagct accgtttcca
     2521 gttaccctgg aaccttttca tgaatatctg agtcagagca tctgtgggtc ataagtgagg
     2581 ccaggacact aagtggcttc attctgatgc ttgactcttt gtaatcataa catttctaaa
     2641 tgctatgaaa acagatttga tccttttttt tggttaatgg ctgccagtgt ggcttgttaa
     2701 tgtgaaaatt catcacaggc caagataata taggacacag gtggattgtg gaaagacact
     2761 cctaggcaac tactcggacc ccattggttc tgatgagcat accaagaagt agttcctacc
     2821 tgttcttaat agctagtcta cttacagatg ttaatcctgt ggtcctttat aaaattcaga
     2881 tcgtccattc tgccccatct tttgaatcca ttttggattg cagtgacagt aactttgtcc
     2941 atattcctca ggttggttga gattgatgat ctgaggatag aactgggggc ctcgtggatg
     3001 ctaggcaagt actctgtcac taagctacat tcctagctgg cctagtctct tagcacagat
     3061 ttctcagtta ttgtagtgtg gataggctga gagttttttt aaaggtacag ttctctttgt
     3121 ttaacaattt cttcttagct tcagtgttct ccccttttca tattttacta aaggcactca
     3181 ggaggaacca agttgctcct tttgaacact ttaattacag ataagtttct gagtctatca
     3241 ctctcaagtt ctaacttcca cacaaaatgt ttctatacag atctgctcgg ttcaatatca
     3301 ctacacacca ctgattgctt tttcttcatg ttctaataac atgttcttcc ttcttaacta
     3361 agggagtcct caccagaata gctggcctct acctgtcact cagtttcaag gctacttgca
     3421 tgtgtttaag tgtgtggttt ttttttgttt tttttttttg tttttttttt ttttactgca
     3481 ttgccacagt accacaaaac actagagctg gcaaaatggc tcagaaggta aaggtgcttg
     3541 tgagcaggaa ctgagtttga tcccagggac ccacacagtc aaaggagagc acggactgct
     3601 acacattagc ctctacttct acatgcatac cacacttgca cacacatgta tacaccataa
     3661 atataacaca aaacagcata aaccaaggtg ctttaaaatt tccctttaaa agaaacaaaa
     3721 ttttaggtta gcataagtat tgggttttat tatggcattt tcatttctat agatcgctgt
     3781 acttctcatt agcttaccac ttttggataa aggtttaggg ctgtgagttt tgctcagtgg
     3841 taatagtcct tacctagcat atgaatagct agttttcatt tcctgcagtg gacagaccat
     3901 atatagcaat ttattttctc acacatgcaa gaataacagc atgggagcta gtgaaatggt
     3961 tcagagggca aagctctttc cctgcaaaca cgagaaccag agtttgcttt ctcagaaccc
     4021 atctaagtgc aggtggctgt gggggcaggc cgcctgtaac cccaaggctt gggaagtaag
     4081 aggggagtcc tcaggctatc tgagtagtta ggttacttga atctacgagc ttcgggctca
     4141 gcaagagacc ctgcttcagt gaataaaatg gaaagtgctt agggaagcct aatattactt
     4201 tctggtttcc acatgccacc tgcaaatgtg gaaacaccaa catgcacatg cacacacatg
     4261 aacacaaaat aacagcatgc ttggcttctg gagtagactc ttcctggcat gcagtcgctt
     4321 tcatatgaca aagtctgaaa atgaggattt tttttttccc tctactcata caaatcgcag
     4381 cattgtggaa tgacgtttcc actcattgtc ctggactatc aaatgaaatt ctaaagaccc
     4441 tatctgaaca gtcatgctga gctttagatt taacatgaat ttgagagggt catagattct
     4501 tttggtttcc tagacaggta atgatatttg tagataatga tgttattttt ttttttctat
     4561 tttagttgtt tccttacata aattagtatg atgtccagca cactagtgaa agtagtaaaa
     4621 gcatattttt ctttagaatt ataatgaggt atgctctcca ttatactgat ttgcttatta
     4681 ggatagaggg tttttttaat atctggattt tgcataatgg ttttatagta tttctttctt
     4741 tgtgaggcaa aattcctctt ggattcatta attgctttcc ctgtatcctc tgagatgact
     4801 atcctcattg gctggtagca ctcaagtatc taggatttca ttgttccata ataataaata
     4861 ctggaatgac taaaaggact ccaaaataaa gcagtcattt attaatgatt atatattatt
     4921 tgttttctga tgttaacttt aaattcttag atacattcaa cttggacatt aaggttcatt
     4981 tttgttttgt gtgattgctg aggatcaaac aagcccagct gaggcaagca ctctgccact
     5041 gagctataat cttgagccca gtggatcgat tctactactt catgttgttt atgcttgctc
     5101 acataaagac taccatagat attcttgagt agcattggca tagaactttt ccttatatgt
     5161 gaagaaatgg agtagggata agaagagtgc ctgtttagca atgcacaagg ctgtggtttc
     5221 agtcctcagc gccaccaaaa cagccagatg taaaacgaac tgactggttt tagctgtaga
     5281 ttagaacagt gtcatacact gcagtgaatg tattcctctc ctgtcctaat tctaaacctg
     5341 ttcaggtatc ctgatttaga ataattgaca ctgttttagg tacccgtttt ctattacctt
     5401 aaactattca gtatctttta tgtttatagg acacctaaga tttacagtat catttaaatt
     5461 ttttgagtat atttttctag gcatgctttc attttcacat atgaaattta ttttttcttg
     5521 tattcctgat gtttcatggt tgcataatta actaactttg ggtctgcctt gtatttcaat
     5581 ctgcaataat ttctccttgt atttaaattg agttaatcct cagtcagtat tcttttggag
     5641 agtatttgtc tcaaactaca gcatgttgcc tcacactgta atcttagggg ttgggaagcc
     5701 aaggcaggag gatcacagat ttaaggggag cctgagcctg ggctattttg tgagacactg
     5761 tcttaagaag acaaaaataa aaaaataaga caagacaaat gtgcccaggg aggagttggg
     5821 gcctggtaaa taatctggga gggaaaaaaa ttttgtcttg aaatacttaa ctttccaata
     5881 tagtttttat ttcattgact ctggcaggta tgtacatggt tatatatttt aattttcttt
     5941 ttgtatcctt ggttaaaaaa aatttggggg ggaggtgcta ggattcaaag tgggggcttt
     6001 acacatgcta taacccaggt gtagatgtgt cttttatata tactttagtt agagttttaa
     6061 aactctgatt acttgaaaat tcctgattaa caattctttt agaccattat gtataatgca
     6121 actagtaaca aaattggaat tttagcaact tttttcttct gtatttgttg catgtacctt
     6181 ttctgtaatg ttttcactga aaattttacc cagtgcttga aatttatgta ctccatttac
     6241 tatttagttg ctattctaaa acattaaatc cagttttaaa ataaaaaaaa aaaaaaaaaa
     6301 aaaaa
//
