LOCUS       NM_011981               3851 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Mus musculus zinc finger protein 260 (Zfp260), mRNA.
ACCESSION   NM_011981
VERSION     NM_011981.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3851)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3851)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   3  (bases 1 to 3851)
  AUTHORS   Komati,H., Maharsy,W., Beauregard,J., Hayek,S. and Nemer,M.
  TITLE     ZFP260 is an inducer of cardiac hypertrophy and a nuclear mediator
            of endothelin-1 signaling
  JOURNAL   J Biol Chem 286 (2), 1508-1516 (2011)
   PUBMED   21051538
  REMARK    GeneRIF: pex1 is a novel nuclear effector of ET-1 signaling and may
            be a regulator of the early stages of cardiac hypertrophy
REFERENCE   4  (bases 1 to 3851)
  AUTHORS   Guo,G., Huss,M., Tong,G.Q., Wang,C., Li Sun,L., Clarke,N.D. and
            Robson,P.
  TITLE     Resolution of cell fate decisions revealed by single-cell gene
            expression analysis from zygote to blastocyst
  JOURNAL   Dev Cell 18 (4), 675-685 (2010)
   PUBMED   20412781
REFERENCE   5  (bases 1 to 3851)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   6  (bases 1 to 3851)
  AUTHORS   Debrus,S., Rahbani,L., Marttila,M., Delorme,B., Paradis,P. and
            Nemer,M.
  TITLE     The zinc finger-only protein Zfp260 is a novel cardiac regulator
            and a nuclear effector of alpha1-adrenergic signaling
  JOURNAL   Mol Cell Biol 25 (19), 8669-8682 (2005)
   PUBMED   16166646
REFERENCE   7  (bases 1 to 3851)
  AUTHORS   Kozak,C.A., Su,Y., Raj,N.B. and Pitha,P.M.
  TITLE     Identification and genetic mapping of differentially expressed
            genes in mice differing at the If1 interferon regulatory locus
  JOURNAL   Mamm Genome 10 (9), 853-857 (1999)
   PUBMED   10441734
REFERENCE   8  (bases 1 to 3851)
  AUTHORS   Blottiere,L., Apiou,F., Ferbus,D., Guenzi,C., Dutrillaux,B.,
            Prosperi,M.T. and Goubin,G.
  TITLE     Cloning, characterization, and chromosome assignment of Zfp146 the
            mouse ortholog of human ZNF146, a gene amplified and overexpressed
            in pancreatic cancer, and Zfp260 a closely related gene
  JOURNAL   Cytogenet Cell Genet 85 (3-4), 297-300 (1999)
   PUBMED   10449921
REFERENCE   9  (bases 1 to 3851)
  AUTHORS   Altomare,D.A., Kozak,C.A., Sonoda,G. and Testa,J.R.
  TITLE     Chromosome mapping of the mouse Akt2 gene and Akt2 pseudogene
  JOURNAL   Cytogenet Cell Genet 74 (4), 248-251 (1996)
   PUBMED   8976376
REFERENCE   10 (bases 1 to 3851)
  AUTHORS   Danciger,M., Brady,J., Adamson,M.C., Farber,D.B., Piatigorsky,J.
            and Kozak,C.A.
  TITLE     Chromosomal localization of the genes for five zinc finger proteins
            expressed in mouse lens
  JOURNAL   Genomics 28 (1), 39-43 (1995)
   PUBMED   7590745
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC085180.1.
            
            On Nov 15, 2004 this sequence version replaced NM_011981.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC085180.1, SRR1660819.93855.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
FEATURES             Location/Qualifiers
     source          1..3851
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 17.26 cM"
     gene            1..3851
                     /gene="Zfp260"
                     /gene_synonym="Ozrf1; PEX1; Zfp63; Znf260"
                     /note="zinc finger protein 260"
                     /db_xref="GeneID:26466"
                     /db_xref="MGI:MGI:1347071"
     exon            1..136
                     /gene="Zfp260"
                     /gene_synonym="Ozrf1; PEX1; Zfp63; Znf260"
                     /inference="alignment:Splign:2.1.0"
     exon            137..331
                     /gene="Zfp260"
                     /gene_synonym="Ozrf1; PEX1; Zfp63; Znf260"
                     /inference="alignment:Splign:2.1.0"
     exon            332..3716
                     /gene="Zfp260"
                     /gene_synonym="Ozrf1; PEX1; Zfp63; Znf260"
                     /inference="alignment:Splign:2.1.0"
     CDS             779..2002
                     /gene="Zfp260"
                     /gene_synonym="Ozrf1; PEX1; Zfp63; Znf260"
                     /note="zfp-260"
                     /codon_start=1
                     /product="zinc finger protein 260"
                     /protein_id="NP_036111.2"
                     /db_xref="CCDS:CCDS21078.1"
                     /db_xref="GeneID:26466"
                     /db_xref="MGI:MGI:1347071"
                     /translation="MLESLQPESHLLHDEPDPGESVYECNECKETFSLEQNFVEHKKT
                     HSGEKSPECTGCGEESSQASSLTLHLRSRPRRESYKCGECGKAFSQRGNFLSHQKQHT
                     EERPSESKKTPVPMTTTVRNQRNTGNKPYACKECGKAFNGKSYLKEHEKIHTGEKPFE
                     CSQCGRAFSQKQYLIKHQNIHSGKKPFKCNECGKAFSQKENLIIHQRIHTGEKPYECK
                     GCGKAFIQKSSLIRHQRSHTGEKPYTCKECGKAFSGKSNLTEHEKIHIGEKPYKCNEC
                     GTIFRQKQYLIKHHNIHTGEKPYECNKCGKAFSRITSLIVHVRIHTGDKPYECKICGK
                     AFCQSSSLTVHMRSHTGEKPYGCNECGKAFSQFSTLALHMRIHTGEKPYQCSECGKAF
                     SQKSHHIRHQRIHIH"
ORIGIN      
        1 gcgaaagaga gagactagaa tggaaaaaga tcctctagtt cagagccctg gtgggcagag
       61 acctctggga gtgctagctc actgaaggag tgcgcaggcg caggcttcgt ggctcgccat
      121 cgtcgccttt gtctggtccc ccttcctgtg tactcccgag accggaagtt tctctaccct
      181 ccagagctct cttgagtgct gaggcttcgg tctgacttgc agccgctgca gagataacgc
      241 ctgagtcctg aattgcttta cctattgcaa gttaaaagtc tacagttcaa acaaaaaccc
      301 tgactgtctg agaagcagca tcaatctgca gaagcggcct ctggagttat acacagataa
      361 ggacacagga tgaaagacgt gtgagttaag tctcagcttt ctgtagagag atagactaaa
      421 aaacaaattc aggaaaccta gaaaacaatt atttcccctg ggcacagaca ttggttctgc
      481 aagagttccc cttatatatg ggattcagtt gaagagaatt tgaactgtga ctttcccaca
      541 ttcgtcattt atgaccacga gagaaactgt aagaaagaac cattgataca aagacagttc
      601 tgtgtttcaa tcccttctaa ccacatctca ggtcacttac gtaaaaagtc tcatctatcg
      661 ggcttcactg gacacttgtg aattaatatc gaaaagaaat cgtatgtact tagtgaatgt
      721 ggcaaagctt tcgtccagtc tcagtagatg ctaggagaga acccctgtgc agatcagaat
      781 gttggagagc cttcagcctg agtcacatct tctgcatgac gaacctgatc ccggagagag
      841 tgtttatgaa tgtaatgaat gtaaggagac cttcagcttg gaacaaaact ttgtagaaca
      901 taagaaaacg catagtggag agaagtcccc tgagtgtaca gggtgtggcg aagagtcctc
      961 acaagcctcc tcattaactc tacatctgag aagtcgccca aggagggagt cctacaagtg
     1021 tggggaatgt gggaaggcct tcagccagag aggaaacttc ctttctcatc agaaacaaca
     1081 taccgaagag agacccagtg aatctaagaa aactcccgtt cccatgacaa ccaccgttag
     1141 aaatcagaga aacacaggga ataaaccata cgcgtgtaag gagtgtggga aagcctttaa
     1201 tggcaagtca tatctcaaag aacacgagaa aattcacacc ggagagaaac cgtttgaatg
     1261 tagtcagtgt ggaagagcct tcagccagaa gcaatacctc attaaacacc agaatatcca
     1321 tagtgggaag aaacctttta agtgtaatga gtgtggtaag gcttttagcc agaaagaaaa
     1381 cctcattata caccagagaa tccatactgg agagaagcct tatgaatgta aagggtgtgg
     1441 gaaagctttc attcagaaat caagcctcat cagacaccag agaagtcata ctggagagaa
     1501 accgtataca tgtaaggaat gtggaaaagc cttcagtggc aaatcaaatc tgactgagca
     1561 tgagaaaatt catattggag agaaacccta taagtgtaac gaatgtggaa cgattttcag
     1621 gcagaaacaa tacctcatca aacatcacaa tattcacacg ggtgaaaagc cctatgagtg
     1681 caataagtgc gggaaagcct tttctcgaat tacatcgctc attgtccatg tgagaattca
     1741 cacaggtgat aaaccctatg aatgtaaaat ctgtgggaaa gccttctgtc agagttcctc
     1801 tcttacagtg catatgagga gccatacggg tgagaaaccc tatggctgca atgaatgtgg
     1861 gaaggccttt tctcagttct caactcttgc tttacacatg agaatccaca ctggggaaaa
     1921 gccttatcag tgcagtgagt gtgggaaggc tttcagccag aagtcccatc acattagaca
     1981 ccagagaatc cacattcatt aaaactcttt gaatgcctta gatgaacgaa cacttgagca
     2041 gagtgtatgg ttagtaatgt atcaaaggat ttgtcttaca ctaagttaca caaatgtagg
     2101 agatgcttct gtagtgactc aaaccttaaa atacaaaggt atttaatagg atagatcata
     2161 gcattatata cttcccagac ccccacaaga aacattatta gtattctaat tttaggagtc
     2221 cagtgattcc aatcagaatg gtcttctaaa gtatatcaac tatattgaga taatatgagc
     2281 aatataaagg tttgaaatta agaggcaaag atatttttga tatacgcttt ggtatataga
     2341 taatttgtag aaattgtttt tcagagaagg cgttttggga cagatctccc tatgtacata
     2401 gcccagggtg accttaaact ccctatgtag cccaagctgg cctccagttt cttctgattc
     2461 acttacccat ctgcccagtg ttgcagttcc agacatcacc aggccaactc aaggtctttg
     2521 ttgataagat tgtctaaact tgaggtcaga acagaatctt gaatctagaa acatgaatga
     2581 attcacagag cattggtaat tgattgtggc agtatcccag gtcagtggga aaatcgtgga
     2641 tgactgaaaa aaataatctc aggataatta actctttgca tgggaaaata ataggcctct
     2701 gatgtcatca ctgatttaga aattacagtg tctttgcaca aagcaaagct ttgtataaga
     2761 attttctagg gtagtttctg agaccctgaa gtaggaaaca aattgtagat tctggattcc
     2821 tcagctattt ttctggagca tttatactta ttcaaagagc tggtatgctt atatagggaa
     2881 tcatgtacca gttgatctct tcatcacagc gtaaattata gtagcaaaaa atgggttcag
     2941 atgtttgttg cttacaaagt agatgaagaa aatgtaatgg tcatgctgta gaatatgcta
     3001 gcagctaagc acaacagatg aatctatgtg tcaacagcaa aagaaaaaaa atcatcagag
     3061 tgaagaattg aaatggtaga tacgttgtga ttcctgcgta aatttgaata aaaccaactt
     3121 accaactctg gtactaagca tcgtttatgg gaaactcttc tctaaaacca gagttgggag
     3181 tatatatatg tgttcagttc ccaaaaccta gttgttgcta ttatagtaac agtggagttc
     3241 cttgggaacg aagttttcac aaagcagggt aatccaatgc tacttcagct ttctagtctt
     3301 catagttaca tatctacttt ccaatagagc agttccaaac aaatgtgaca gatggatact
     3361 tggctctaca ttgtagtaac acgtaatctt tgttatcttg cttaggtaga catggatgag
     3421 atgtacacga gatgcatatt atcacaacgg tcccattgtg cgtgtgtgca tcccaaggcc
     3481 cctcatggat atctgaagcc ttgtgtagta ttaactctct ctatcaggtt ttcctatgta
     3541 catacatccc taggctgatg tttataagca ccacaagagt cttcacgtca aagaattaca
     3601 actccacttc cacctcagta ttcttgggct ttggaaccat tgttaagtaa aataaatgtt
     3661 gctgggtagt ttctgcccat tgattggact cagactaata aattttggaa aagtccaaaa
     3721 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     3781 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     3841 aaaaaaaaaa a
//
