LOCUS       NM_027248               2938 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus zinc finger protein 219 (Zfp219), transcript variant
            1, mRNA.
ACCESSION   NM_027248
VERSION     NM_027248.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2938)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2938)
  AUTHORS   El Abdellaoui-Soussi,F., Yunes-Leites,P.S., Lopez-Maderuelo,D.,
            Garcia-Marques,F., Vazquez,J., Redondo,J.M. and Gomez-Del Arco,P.
  TITLE     Interplay between the Chd4/NuRD Complex and the Transcription
            Factor Znf219 Controls Cardiac Cell Identity
  JOURNAL   Int J Mol Sci 23 (17), 9565 (2022)
   PUBMED   36076959
  REMARK    GeneRIF: Interplay between the Chd4/NuRD Complex and the
            Transcription Factor Znf219 Controls Cardiac Cell Identity.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2938)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2938)
  AUTHORS   Shimizu,H., Kubo,A., Uchibe,K., Hashimoto,M., Yokoyama,S.,
            Takada,S., Mitsuoka,K. and Asahara,H.
  TITLE     The AERO system: a 3D-like approach for recording gene expression
            patterns in the whole mouse embryo
  JOURNAL   PLoS One 8 (10), e75754 (2013)
   PUBMED   24146773
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2938)
  AUTHORS   Wiese,C.B., Ireland,S., Fleming,N.L., Yu,J., Valerius,M.T.,
            Georgas,K., Chiu,H.S., Brennan,J., Armstrong,J., Little,M.H.,
            McMahon,A.P. and Southard-Smith,E.M.
  TITLE     A genome-wide screen to identify transcription factors expressed in
            pelvic Ganglia of the lower urinary tract
  JOURNAL   Front Neurosci 6, 130 (2012)
   PUBMED   22988430
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 2938)
  AUTHORS   Zhou,Q., Law,A.C., Rajagopal,J., Anderson,W.J., Gray,P.A. and
            Melton,D.A.
  TITLE     A multipotent progenitor domain guides pancreatic organogenesis
  JOURNAL   Dev Cell 13 (1), 103-114 (2007)
   PUBMED   17609113
REFERENCE   7  (bases 1 to 2938)
  AUTHORS   Yoshikawa,T., Piao,Y., Zhong,J., Matoba,R., Carter,M.G., Wang,Y.,
            Goldberg,I. and Ko,M.S.
  TITLE     High-throughput screen for genes predominantly expressed in the ICM
            of mouse blastocysts by whole mount in situ hybridization
  JOURNAL   Gene Expr Patterns 6 (2), 213-224 (2006)
   PUBMED   16325481
REFERENCE   8  (bases 1 to 2938)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
REFERENCE   9  (bases 1 to 2938)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   10 (bases 1 to 2938)
  AUTHORS   Hildebrand,J.D. and Soriano,P.
  TITLE     Overlapping and unique roles for C-terminal binding protein 1
            (CtBP1) and CtBP2 during mouse development
  JOURNAL   Mol Cell Biol 22 (15), 5296-5307 (2002)
   PUBMED   12101226
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AB063578.1, BQ890732.1, AK008516.1 and AK053445.1.
            
            On Mar 21, 2009 this sequence version replaced NM_027248.1.
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (1). Variants 1-3 encode the same isoform 1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB063578.1, SRR7974084.27845.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-435               AB063578.1         1-435
            436-1048            BQ890732.1         72-684
            1049-2156           AK008516.1         367-1474
            2157-2938           AK053445.1         1996-2777
FEATURES             Location/Qualifiers
     source          1..2938
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 26.76 cM"
     gene            1..2938
                     /gene="Zfp219"
                     /gene_synonym="2010302A17Rik; Znf219"
                     /note="zinc finger protein 219"
                     /db_xref="GeneID:69890"
                     /db_xref="MGI:MGI:1917140"
     exon            1..211
                     /gene="Zfp219"
                     /gene_synonym="2010302A17Rik; Znf219"
                     /inference="alignment:Splign:2.1.0"
     exon            212..300
                     /gene="Zfp219"
                     /gene_synonym="2010302A17Rik; Znf219"
                     /inference="alignment:Splign:2.1.0"
     CDS             295..2475
                     /gene="Zfp219"
                     /gene_synonym="2010302A17Rik; Znf219"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="zinc finger protein 219 isoform 1"
                     /protein_id="NP_081524.2"
                     /db_xref="CCDS:CCDS36916.1"
                     /db_xref="GeneID:69890"
                     /db_xref="MGI:MGI:1917140"
                     /translation="MEGSRPRILVGHLEPSPPAFDGELDLQRYSNGPGVSGTPGPGSP
                     GMGAVGWSETRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRA
                     LLRSHLRTHQPERPRSPAARLLLELEERALLREARLGRARSSGGMQSSPAAEGLARPQ
                     VPSSSAFRCPFCKGKFRTSAERERHLHILHRPWKCSLCSFGSSQEEELLHHSLTAHGA
                     SERPLAATSTPEPPPPPQQEPRSALEPEPEPEPRPEPDREANPAPTPAPPEEPPAPPE
                     FRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHTSKLGPL
                     RAPGPGSAPARAPQPPDLSLLAYEPLGPALLLAPAPAPAERREPPSLLGYLSVRAGEV
                     RPNGEGADPGGGRSYGGFRPLPSALPNRARRHRTEEPEEEEEVVEAEEESWARGRSLG
                     SLTSLHPNPGEGSGQPAPAAGTQARSTATQEENGLLVGGTRSEAGRGATGKDCPFCGK
                     SFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSSAGPGPPPE
                     PPPPSQRGSLQPQSGAKPTQASATWVEGTASTRPPSSSTGPGSRRKPASPGRTLRNGR
                     GGEAEPLDLSLRAGPGGEAGAGGALHRCLFCPFATGAPELMALHLQVHHSRRARGRRQ
                     PRADTSPTYVRAPSGETPPSPPLEEEGSPGLSRSGEAGLGGQER"
     exon            301..1735
                     /gene="Zfp219"
                     /gene_synonym="2010302A17Rik; Znf219"
                     /inference="alignment:Splign:2.1.0"
     exon            1736..1867
                     /gene="Zfp219"
                     /gene_synonym="2010302A17Rik; Znf219"
                     /inference="alignment:Splign:2.1.0"
     exon            1868..2938
                     /gene="Zfp219"
                     /gene_synonym="2010302A17Rik; Znf219"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2909..2914
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp219"
                     /gene_synonym="2010302A17Rik; Znf219"
                     /note="hexamer: AATAAA"
     polyA_site      2933
                     /gene="Zfp219"
                     /gene_synonym="2010302A17Rik; Znf219"
                     /note="major polyA site"
ORIGIN      
        1 ccactcccaa ggtgtcacaa acagaaagga tctgcagctg gcgccactgc aatgtcaagg
       61 caagccagcc aggctgcgct ctagcctcac tggtacctgg gcttgcctga gcccggagaa
      121 gcagcattct ctagggaaaa gaagccttct caagtgggaa caaaaatgaa tgtgaggcga
      181 acacccatcc cgggcactat gtgaatttgg gcacctccgc acctgttgcc ttcattagca
      241 gcttttcttc ttcctccttc caatcctcag aaccaaagaa tgtgaagggg gtccatggag
      301 ggctcacgtc cccgcatcct ggtcggccac ctagagcctt ccccaccagc cttcgacggc
      361 gagctggatc tgcagcgcta ctccaacgga ccaggtgtca gtgggactcc aggacccggc
      421 tcgcctggga tgggagcagt gggttggtct gagactcgtg caggcgaacg gcgcttccct
      481 tgtcctgtgt gcggaaagcg cttccgattc aattccatct tggctttgca cctgagagcc
      541 cacccgggcg cccaagcctt ccagtgccca cattgcggcc accgcgcagc gcagcgggct
      601 ctgctgcgct cacacctccg aacgcaccag ccggagcgtc cacgcagccc tgctgcacgg
      661 ctgttgctgg agttggagga acgcgccctg cttcgcgaag cccgactcgg gagagccaga
      721 agctcaggcg gcatgcagtc cagccctgcc gcagagggcc tggctcgccc tcaggtccct
      781 tcctcatctg ccttccgttg ccctttctgc aaaggcaagt ttcgcacctc agcggagcgg
      841 gaacgccacc tgcatatcct gcacaggccc tggaagtgca gcttgtgcag ttttggctcc
      901 agccaggagg aggagttgct gcaccacagt ctgacggccc acggggcttc cgagcgcccc
      961 ctggcggcta catctacgcc tgaacccccg cctccacccc agcaagaacc cagatctgcc
     1021 cttgagcctg agcctgagcc tgaacctagg ccagagcctg accgggaggc aaaccctgcc
     1081 ccaactcctg cacctccgga ggagccccct gcgccacctg aattccgttg ccaggtgtgc
     1141 ggccagagct ttacacagtc ctggtttctc aagggtcaca tgcgcaagca caaggcctcc
     1201 tttgatcatg cgtgccccgt atgtggtcgc tgcttcaagg agccctggtt ccttaagaac
     1261 cacatgaagg tgcacaccag caagctgggt cctttgcgtg ctccaggccc tggctctgca
     1321 cctgccaggg cccctcagcc tcccgacctg agcctactgg catatgagcc actgggccct
     1381 gcactcctcc tggccccagc acccgctccg gctgagcgcc gagagccccc aagcctctta
     1441 ggctacctga gtgtacgagc tggggaagta cgacccaatg gtgagggtgc tgaccctgga
     1501 ggtggccgaa gctatggagg gttccgccca ctgccttcag ctcttcccaa ccgggctcgg
     1561 cgacaccgta cagaggaacc agaagaggaa gaagaagtgg tggaggctga agaggagagc
     1621 tgggcccgag gcaggtcgct gggctctctg acttccctgc accccaaccc aggtgagggg
     1681 tcaggacagc ctgcacctgc cgcggggacc caggcgagat ccacggccac ccaagaagaa
     1741 aacgggctgc tggttggagg gacacgatct gaagcgggcc gtggggccac tggcaaggac
     1801 tgccccttct gtggaaaatc tttccgctcg gcgcatcact taaaagtgca tctccgtgtg
     1861 cacacaggtg agcgtcccta caagtgtcca cactgcgact atgcaggtac ccagtcgggc
     1921 tcgctcaagt atcaccttca gcgtcaccac cgagagcaga ggagcagtgc gggtcctggg
     1981 cctcccccag aacccccgcc accttcccag cggggctcac tgcagccgca gtcaggagcc
     2041 aagccaactc aggcctcagc cacctgggta gagggcactg caagtacccg gcctccttcg
     2101 agcagcaccg gaccagggtc ccgtaggaag cctgctagcc ctgggaggac cctgcgaaac
     2161 gggcgaggtg gtgaagccga acccctggac ctgtccctac gggcgggccc gggaggtgag
     2221 gccggggcag ggggtgccct tcaccgctgc ctcttctgcc cctttgccac tggagctcct
     2281 gagctcatgg ccttgcatct gcaagtacac catagccgtc gtgctcgggg ccgccggcag
     2341 ccccgagccg acacgtctcc aacctatgtc cgggcaccat caggagagac ccctcccagt
     2401 cctccactag aagaggaggg cagcccaggg ctgtctagat ccggagaggc aggtcttggg
     2461 gggcaagaac ggtagggagc cctcttagga gtgattagct tagtaagctt accccgcagg
     2521 agcggggaag tgctagaggt agttgggtag agcagccagc agggagcagt gtgggacccg
     2581 tatcccagcc caaggtggac caagaggtaa agtgggcagt gggtggagga gagtgggcta
     2641 gcagcaccca cccagcccag aggagtcaca gtgccttaga agtggcagag gtgagggtca
     2701 aagaacgggg tcctcgggct ggtagaggat gtgttcctgt taaggagccg ctctgccagt
     2761 tcctgctggt ccataggcat gagagtttat ttttgtataa ggggtggggg tggggggcac
     2821 tgtacccttc tagccctatc aggggccctt gtagacgttg ctatttttgg tacgattcct
     2881 gtcatccctg ttgaagagtc atgtccccaa taaacaggtg tcttgaggca caaggccc
//
