LOCUS       NP_001123641             495 aa            linear   ROD 27-APR-2025
DEFINITION  BUB3-interacting and GLEBS motif-containing protein ZNF207 isoform
            1 [Mus musculus].
ACCESSION   NP_001123641
VERSION     NP_001123641.1
DBSOURCE    REFSEQ: accession NM_001130169.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 495)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (residues 1 to 495)
  AUTHORS   Malla,S., Prasad Bhattarai,D., Groza,P., Melguizo-Sanchis,D.,
            Atanasoai,I., Martinez-Gamero,C., Roman,A.C., Zhu,D., Lee,D.F.,
            Kutter,C. and Aguilo,F.
  TITLE     ZFP207 sustains pluripotency by coordinating OCT4 stability,
            alternative splicing and RNA export
  JOURNAL   EMBO Rep 23 (3), e53191 (2022)
   PUBMED   35037361
  REMARK    GeneRIF: ZFP207 sustains pluripotency by coordinating OCT4
            stability, alternative splicing and RNA export.
REFERENCE   3  (residues 1 to 495)
  AUTHORS   Zhang,J., Liu,W., Li,G., Xu,C., Nie,X., Qin,D., Wang,Q., Lu,X.,
            Liu,J. and Li,L.
  TITLE     BCAS2 is involved in alternative splicing and mouse oocyte
            development
  JOURNAL   FASEB J 36 (2), e22128 (2022)
   PUBMED   34972250
REFERENCE   4  (residues 1 to 495)
  AUTHORS   Wang,A., Wang,J., Tian,K., Huo,D., Ye,H., Li,S., Zhao,C., Zhang,B.,
            Zheng,Y., Xu,L., Hua,X., Wang,K., Wu,Q.F., Wu,X., Zeng,T., Liu,Y.
            and Zhou,Y.
  TITLE     An epigenetic circuit controls neurogenic programs during neocortex
            development
  JOURNAL   Development 148 (22) (2021)
   PUBMED   35020876
REFERENCE   5  (residues 1 to 495)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   6  (residues 1 to 495)
  AUTHORS   Tamplin,O.J., Kinzel,D., Cox,B.J., Bell,C.E., Rossant,J. and
            Lickert,H.
  TITLE     Microarray analysis of Foxa2 mutant mouse embryos reveals novel
            gene expression and inductive roles for the gastrula organizer and
            its derivatives
  JOURNAL   BMC Genomics 9, 511 (2008)
   PUBMED   18973680
  REMARK    Publication Status: Online-Only
REFERENCE   7  (residues 1 to 495)
  AUTHORS   Evsikov,A.V., Graber,J.H., Brockman,J.M., Hampl,A., Holbrook,A.E.,
            Singh,P., Eppig,J.J., Solter,D. and Knowles,B.B.
  TITLE     Cracking the egg: molecular dynamics and evolutionary aspects of
            the transition from the fully grown oocyte to embryo
  JOURNAL   Genes Dev 20 (19), 2713-2727 (2006)
   PUBMED   17015433
REFERENCE   8  (residues 1 to 495)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
REFERENCE   9  (residues 1 to 495)
  AUTHORS   Misawa,K., Nosaka,T., Morita,S., Kaneko,A., Nakahata,T., Asano,S.
            and Kitamura,T.
  TITLE     A method to identify cDNAs based on localization of green
            fluorescent protein fusion products
  JOURNAL   Proc Natl Acad Sci U S A 97 (7), 3062-3066 (2000)
   PUBMED   10716735
REFERENCE   10 (residues 1 to 495)
  AUTHORS   Taguchi,E., Muramatsu,H., Fan,Q.W., Kurosawa,N., Sobue,G. and
            Muramatsu,T.
  TITLE     Zep: A novel zinc finger protein containing a large proline-rich
            domain
  JOURNAL   J Biochem 124 (6), 1220-1228 (1998)
   PUBMED   9832628
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB666896.1, AK146787.1 and DV661373.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660811.222574.1,
                                           SRR1660813.273033.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..495
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 47.83 cM"
     Protein         1..495
                     /product="BUB3-interacting and GLEBS motif-containing
                     protein ZNF207 isoform 1"
                     /note="49 kDa zinc finger protein; BUB3-interacting and
                     GLEBS motif-containing protein ZNF207"
                     /calculated_mol_wt=52662
     Region          1..92
                     /region_name="Microtubule-binding region.
                     /evidence=ECO:0000250|UniProtKB:O43670"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9JMD0.1)"
     Region          10..90
                     /region_name="SUF4-like"
                     /note="N-terminal domain of Oryza sativa transcription
                     factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana
                     SUF4 (AtSUF4), and similar proteins; cd20908"
                     /db_xref="CDD:411020"
     Region          13..34
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:411020"
     Region          13..34
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275371"
     Site            order(18,24,31,33,36,43)
                     /site_type="other"
                     /note="putative DNA binding site [nucleotide binding]"
                     /db_xref="CDD:411020"
     Region          37..58
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:411020"
     Region          99..161
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9JMD0.1)"
     Region          252..292
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9JMD0.1)"
     Region          316..372
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9JMD0.1)"
     Region          376..408
                     /region_name="GLEBS.
                     /evidence=ECO:0000250|UniProtKB:O43670"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9JMD0.1)"
     Region          <437..472
                     /region_name="SMN"
                     /note="Survival motor neuron protein (SMN); pfam06003"
                     /db_xref="CDD:428716"
     Region          462..495
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9JMD0.1)"
     CDS             1..495
                     /gene="Zfp207"
                     /gene_synonym="8430401D15Rik; BuGZ; Zep; Znf207"
                     /coded_by="NM_001130169.1:177..1664"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /db_xref="CCDS:CCDS48863.1"
                     /db_xref="GeneID:22680"
                     /db_xref="MGI:MGI:1340045"
ORIGIN      
        1 mgrkkkkqlk pwcwycnrdf ddekiliqhq kakhfkchic hkklytgpgl aihcmqvhke
       61 tidavpnaip grtdieleiy gmegipekdm derrrlleqk tqesqkkkqq ddsdeyddde
      121 saastsfqpq pvqpqqgyip pmaqpglppv pgapgmppgi pplmpgvppl mpgmppvmpg
      181 mppglhhqrk ytqsfcgeni mmpmggmmpp gpgipplmpg mppgmpppvp rpgippmtqa
      241 qavsapgiln rppaptaavp apqppvtkpl fpsagqmgtp vtssstassn seslsasska
      301 lfpstaqaqa avqgpvgtdf kplnstpaat tteppkptfp aytqstastt sttnstaakp
      361 aasitskpat ltttsatskl ihpdedisle erraqlpkyq rnlprpgqtp ignppvgpig
      421 gmmppqpglp qqqamrppmp phgqygghhq gmpgylpgam ppygqgppmv ppyqggpprp
      481 pmgmrppvms qggry
//
