LOCUS       NM_030713               3877 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus zinc finger protein 202 (Zfp202), transcript variant
            1, mRNA.
ACCESSION   NM_030713
VERSION     NM_030713.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3877)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3877)
  AUTHORS   Vrins,C.L., Out,R., van Santbrink,P., van der Zee,A., Mahmoudi,T.,
            Groenendijk,M., Havekes,L.M., van Berkel,T.J., Willems van Dijk,K.
            and Biessen,E.A.
  TITLE     Znf202 affects high density lipoprotein cholesterol levels and
            promotes hepatosteatosis in hyperlipidemic mice
  JOURNAL   PLoS One 8 (2), e57492 (2013)
   PUBMED   23469003
  REMARK    GeneRIF: Znf202 overexpression in vivo reveals an important role of
            this transcriptional regulator in liver lipid homeostasis, while
            firmly establishing the proposed key role in the control of HDL
            levels
REFERENCE   3  (bases 1 to 3877)
  AUTHORS   Guo,G., Huss,M., Tong,G.Q., Wang,C., Li Sun,L., Clarke,N.D. and
            Robson,P.
  TITLE     Resolution of cell fate decisions revealed by single-cell gene
            expression analysis from zygote to blastocyst
  JOURNAL   Dev Cell 18 (4), 675-685 (2010)
   PUBMED   20412781
REFERENCE   4  (bases 1 to 3877)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   5  (bases 1 to 3877)
  AUTHORS   Patterson,E.S., Addis,R.C., Shamblott,M.J. and Gearhart,J.D.
  TITLE     SOX17 directly activates Zfp202 transcription during in vitro
            endoderm differentiation
  JOURNAL   Physiol Genomics 34 (3), 277-284 (2008)
   PUBMED   18523156
  REMARK    GeneRIF: SOX17-Chromatin immunoprecipitation identified zinc finger
            protein 202 (Zfp202) as a direct target of SOX17 during endoderm
            differentiation of F9 embryonal carcinoma cells.
REFERENCE   6  (bases 1 to 3877)
  AUTHORS   Honer,C., Chen,P., Toth,M.J. and Schumacher,C.
  TITLE     Identification of SCAN dimerization domains in four gene families
  JOURNAL   Biochim Biophys Acta 1517 (3), 441-448 (2001)
   PUBMED   11342224
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC136021.5, BC049772.1 and AC135353.3.
            
            On Sep 11, 2009 this sequence version replaced NM_030713.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC049772.1, AF292648.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849382, SAMN00849384
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-72                AC136021.5         16375-16446         c
            73-3462             BC049772.1         1-3390
            3463-3877           AC135353.3         127444-127858       c
FEATURES             Location/Qualifiers
     source          1..3877
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 21.42 cM"
     gene            1..3877
                     /gene="Zfp202"
                     /gene_synonym="C130037E22Rik; Znf202"
                     /note="zinc finger protein 202"
                     /db_xref="GeneID:80902"
                     /db_xref="MGI:MGI:1933401"
     exon            1..122
                     /gene="Zfp202"
                     /gene_synonym="C130037E22Rik; Znf202"
                     /inference="alignment:Splign:2.1.0"
     exon            123..618
                     /gene="Zfp202"
                     /gene_synonym="C130037E22Rik; Znf202"
                     /inference="alignment:Splign:2.1.0"
     CDS             217..2142
                     /gene="Zfp202"
                     /gene_synonym="C130037E22Rik; Znf202"
                     /note="isoform 1 is encoded by transcript variant 1; zinc
                     finger 202"
                     /codon_start=1
                     /product="zinc finger protein 202 isoform 1"
                     /protein_id="NP_109638.2"
                     /db_xref="CCDS:CCDS23079.1"
                     /db_xref="GeneID:80902"
                     /db_xref="MGI:MGI:1933401"
                     /translation="MATALEPEDQDLWEEEGVLMVKLEDDFTCGPESALEGDDPVLET
                     SHQNFRRFRYQEASSPREALIRLRELCHQWLRPERRTKEQILELLVLEQFLTVLPGEL
                     QSWVRGQRPESGEEAVTLVEGLQKQPRRPRRWVTVHVQGQEVLSEETLHLGLEPESSS
                     EQQDPTQTLTTEQPHEEALRSPDLGTQEQETLQHDEEHLPLPECEVPVSQDVDLPTEQ
                     GSGHPEMVALLTALSQGLVTFKDVALCFSQDQWSDLDPTQKEFYGEYVLEEDCGIVVS
                     LSFPIPRLDDTSQIREEEPQVPGVHESQEPAEPEILSFTYTGDMSEAEEESVEQQDTH
                     KSTLANTEVHQSPDWEIVIEDNTSRLNERFGTNVSKVNSFTNIRETMPVHSQSGRQHH
                     CPLCAKSFTCNSHLIRHLRTHTGEKPYKCMECGKSYTRSSHLARHQKVHKMNTPHKHP
                     PNRKTVDGPLVQSEVTTRVEKPYTCDDCGKHFRWTSDLVRHQRTHTGEKPFFCTICSK
                     SFSQKSVLTTHQRIHVGGKPYVCANCGENFSEQKQYLTHRKTHVSEEHHLCNECGRSF
                     SHSAAFAKHLKGHASVRNCRCDECGKTFSRRDHLVRHQRTHTGEKPFTCATCGKSFSR
                     GYHLIRHQRVHTGKTKT"
     exon            619..829
                     /gene="Zfp202"
                     /gene_synonym="C130037E22Rik; Znf202"
                     /inference="alignment:Splign:2.1.0"
     exon            830..918
                     /gene="Zfp202"
                     /gene_synonym="C130037E22Rik; Znf202"
                     /inference="alignment:Splign:2.1.0"
     exon            919..1048
                     /gene="Zfp202"
                     /gene_synonym="C130037E22Rik; Znf202"
                     /inference="alignment:Splign:2.1.0"
     exon            1049..1168
                     /gene="Zfp202"
                     /gene_synonym="C130037E22Rik; Znf202"
                     /inference="alignment:Splign:2.1.0"
     exon            1169..3877
                     /gene="Zfp202"
                     /gene_synonym="C130037E22Rik; Znf202"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3219..3224
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp202"
                     /gene_synonym="C130037E22Rik; Znf202"
                     /note="hexamer: AGTAAA"
     polyA_site      3248
                     /gene="Zfp202"
                     /gene_synonym="C130037E22Rik; Znf202"
                     /note="major polyA site"
     regulatory      3438..3443
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp202"
                     /gene_synonym="C130037E22Rik; Znf202"
                     /note="hexamer: ATTAAA"
     polyA_site      3462
                     /gene="Zfp202"
                     /gene_synonym="C130037E22Rik; Znf202"
                     /note="major polyA site"
ORIGIN      
        1 cagaggaccc acgtgttccg acccgctggg ccccgcgcga ctcggatccc gctcggctct
       61 ttcggccggg agtgggtggg ggagcaccgg gcaggggagg agccgccgga gccgcgggag
      121 acgtccctta ggaggaaccc cttgagctac ccggtctaaa acacgttatc gccagtgtga
      181 gggctaaatg gtgtgataac acccaagagc caggaaatgg caacagcctt ggagccagag
      241 gaccaagatc tttgggaaga agaaggagtt ctgatggtga aactggagga tgatttcacg
      301 tgcgggccag aatccgcctt ggagggcgat gatcctgtac tggagacctc tcaccagaac
      361 ttccgacgct ttcgatacca ggaagcatca agccctcgag aagctctcat cagacttcga
      421 gagctttgtc atcagtggct gaggccagag aggagaacta aggagcagat tcttgagctg
      481 ctcgtgttgg agcagttcct cactgtcctg cctggagaac tgcagagctg ggtgcgaggc
      541 cagcggcccg agagtggcga ggaggcagtg acgctggtgg agggtttgca gaaacaaccc
      601 aggagaccaa ggcggtgggt aaccgtccat gttcagggcc aggaagtcct gtcagaggag
      661 accctacacc tagggctgga gccggagtcc tccagtgagc aacaagatcc aacacagacc
      721 ttgaccactg agcagcccca tgaggaagcc ctccgaagcc cagatctggg gacacaggaa
      781 caggagacct tgcagcatga cgaggagcac ctgcccctgc cggaatgtga ggttccagtg
      841 tcccaggatg tagaccttcc cacagaacaa gggtctggac acccagagat ggttgctctt
      901 ctcactgctc tctctcaggg actggtcaca ttcaaggatg tggctctgtg cttctcacag
      961 gatcagtgga gtgatctgga tccaacacaa aaagaattct atggagagta tgtcttggaa
     1021 gaagactgtg gaattgtggt ctctctgtca tttccaattc ccagactaga tgatacctcc
     1081 cagattagag aagaagagcc tcaggtccca ggtgtccatg agtctcaaga gcctgcagaa
     1141 ccagaaatcc tgagttttac ctatacagga gacatgagtg aagctgagga agaaagtgtt
     1201 gagcaacaag atacacacaa gtctactttg gcaaacacag aagttcacca gtctccagat
     1261 tgggaaatag tcattgagga taataccagt agacttaatg aaagatttgg tacaaacgtt
     1321 tctaaagtta atagtttcac aaatattagg gaaactatgc ctgttcactc ccaatcaggg
     1381 aggcagcatc attgccctct atgtgcaaaa agcttcacgt gtaattctca tcttattagg
     1441 cacttaagaa ctcacacagg agaaaaaccc tataaatgta tggagtgtgg gaaaagttac
     1501 acacggagct cacatctagc taggcaccag aaagtccata agatgaacac tcctcataaa
     1561 catcctccaa accggaagac tgtggatggc cctctggtcc agtctgaggt aactacccgt
     1621 gtggagaaac catatacctg tgatgattgt ggaaaacatt tccgttggac gtcggacctg
     1681 gtcaggcacc agaggacaca tacaggagaa aaaccttttt tctgtactat ctgtagcaaa
     1741 agcttcagcc agaaatctgt gttaacgaca caccaaagaa tccatgttgg aggcaagccc
     1801 tacgtgtgtg cgaactgtgg cgagaacttc agtgagcaga agcagtatct gacacaccgc
     1861 aagacacacg tgtctgagga gcaccatctg tgcaatgagt gtggccgctc cttcagccat
     1921 agtgcagcat ttgccaagca cctgaaaggc catgcttcag tgaggaactg ccgctgcgat
     1981 gagtgtggta aaacctttag caggagggat caccttgtca gacatcaacg aacacacact
     2041 ggggaaaagc cttttacctg tgccacctgt gggaaaagct tcagcagagg ctatcactta
     2101 atccggcatc agagagtcca cacaggaaag accaagacct agctaggggc cttatgtgga
     2161 gagcttaatt ccgccgccaa ctgagacgga tgggttctgt gttcaacctg agaagaactc
     2221 ttctgaggca tctctgacct gcccgtacct tacatcacct cttccaacta ccaaacaaaa
     2281 gccccatcca gaacgactca gcttttctca gttgaggctt ctgtttcact ggcatgctcc
     2341 tgcctctacc tcataggtgt ggtgtaggag atgtgggact taaggaaatt tgggtcactg
     2401 tattttgaga aacataggct gctctagatc ctggagacta cttgacagcc tcaacttcag
     2461 tgtggtcaag gataagtacg taggtctgat aagcgaccaa cttaaaacgg tctgtcctta
     2521 ctggactcaa accttaaagc acaaaaccct aaactcaaga taggaggttt gggtcctgat
     2581 agatttgcca cactgacggg atagctacag tttctcacta actcgcctct tcactgtaca
     2641 ctttcctttg atgctggaga caaaggggaa gaattttgaa ggacaaatcc ttaaggctcc
     2701 ttcacaagga ttttgacagg ctgctccttt ccccattgtc agaatgacac taagtgccac
     2761 atactgctac aaaagcgggc ctaagcaaaa gcctcttggg gtgtaccacc cctgtctaaa
     2821 tactcctgtc tactattcag ccactgtcag tttgtccctt acatgcctac tgcaaaagag
     2881 gtgtagtact ggagtgctga agaactcagt aaagcataat taagacatgg tgaaatccat
     2941 tccattccca cataatgttt aagcctgccc tccttcattt ggcttgtgag aagggatcta
     3001 aagctcttgt tagcatagaa aggcactgta tctagtgcag aatcataatt gactgagaga
     3061 gactagagga gatataaaac cagttcggaa gactatgaaa cagctgttgc cactggctga
     3121 gactattctg acacccagtc cttggtatcc ctgcctgggt tctctaattt ctgggaagat
     3181 tatgaaccct agtacttggg accctgagaa ttcatcagag taaagggatt tttatgtgtc
     3241 ttgtgttact tggtttttca tgtgtaagtt cattttcatg taattgtgaa ctaaaaagta
     3301 gtatctcctg gtggcctacg ggtcttttac ctgttcaatg ttcccaggag gctgaaattt
     3361 tatgacctta catgtctgat catctatctg aaaaggactg aggacagata ttccataaat
     3421 ggggcacagg atgtgggatt aaagcatgag aaggaagata tacatctatg cctggtttct
     3481 tctgcttatt ttacaatcac aaagggatat ggtgggttag caggcatctt ctcagctcta
     3541 atccaatagg gaaattctct taacgatgga ctagtcaaat tttaatgcca gtcaatcatt
     3601 gtcgtgaaga tacataagaa ataaataaag tgggctggag agatggctca gtggttaaga
     3661 gcactgactg ctcttctgga ggtcctgagt tcaaatccca gcaaccgcat ggtggctcac
     3721 aaccatctgt aatgagatct gatgccctct tctggtatgt ttgaagacag ctacagtgta
     3781 cttacatata ataaaataaa acaataaatc ttggggccgg agtgagaaga caaaaaaaaa
     3841 ttatttaaaa gaaagaaata aagtgatatt tgcaacc
//
