LOCUS       NM_011748               3491 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus zinc finger protein 14 (Zfp14), transcript variant 1,
            mRNA.
ACCESSION   NM_011748
VERSION     NM_011748.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3491)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3491)
  AUTHORS   Mohibi,S., Chen,M., Chen,X. and Zhang,J.
  TITLE     Poly zinc finger protein ZFP14 suppresses lymphomagenesis and
            abnormal inflammatory response via the HOXA gene cluster
  JOURNAL   Biochim Biophys Acta Mol Basis Dis 1869 (1), 166587 (2023)
   PUBMED   36349645
  REMARK    GeneRIF: Poly zinc finger protein ZFP14 suppresses lymphomagenesis
            and abnormal inflammatory response via the HOXA gene cluster.
REFERENCE   3  (bases 1 to 3491)
  AUTHORS   Cui,W., Dai,X., Marcho,C., Han,Z., Zhang,K., Tremblay,K.D. and
            Mager,J.
  TITLE     Towards Functional Annotation of the Preimplantation Transcriptome:
            An RNAi Screen in Mammalian Embryos
  JOURNAL   Sci Rep 6, 37396 (2016)
   PUBMED   27869233
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3491)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   5  (bases 1 to 3491)
  AUTHORS   Wiese,C.B., Ireland,S., Fleming,N.L., Yu,J., Valerius,M.T.,
            Georgas,K., Chiu,H.S., Brennan,J., Armstrong,J., Little,M.H.,
            McMahon,A.P. and Southard-Smith,E.M.
  TITLE     A genome-wide screen to identify transcription factors expressed in
            pelvic Ganglia of the lower urinary tract
  JOURNAL   Front Neurosci 6, 130 (2012)
   PUBMED   22988430
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 3491)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   7  (bases 1 to 3491)
  AUTHORS   Chavrier,P., Lemaire,P., Revelant,O., Bravo,R. and Charnay,P.
  TITLE     Characterization of a mouse multigene family that encodes zinc
            finger structures
  JOURNAL   Mol Cell Biol 8 (3), 1319-1326 (1988)
   PUBMED   2452975
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY128777.1, AK045631.1, AK032214.1 and AK030632.1.
            
            On Dec 14, 2005 this sequence version replaced NM_011748.1.
            
            Transcript Variant: This variant (1) represents the longest
            transcript. Variants 1, 2 and 3 encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK045631.1, SRR7345562.1158489.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-52                BY128777.1         2-53
            53-433              AK045631.1         23-403
            434-2957            AK032214.1         355-2878
            2958-3491           AK030632.1         2764-3297
FEATURES             Location/Qualifiers
     source          1..3491
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 17.26 cM"
     gene            1..3491
                     /gene="Zfp14"
                     /gene_synonym="4732429I09Rik; Krox-9; mKIAA1559; Zfp-14"
                     /note="zinc finger protein 14"
                     /db_xref="GeneID:243906"
                     /db_xref="MGI:MGI:99160"
     exon            1..52
                     /gene="Zfp14"
                     /gene_synonym="4732429I09Rik; Krox-9; mKIAA1559; Zfp-14"
                     /inference="alignment:Splign:2.1.0"
     exon            53..116
                     /gene="Zfp14"
                     /gene_synonym="4732429I09Rik; Krox-9; mKIAA1559; Zfp-14"
                     /inference="alignment:Splign:2.1.0"
     exon            117..217
                     /gene="Zfp14"
                     /gene_synonym="4732429I09Rik; Krox-9; mKIAA1559; Zfp-14"
                     /inference="alignment:Splign:2.1.0"
     exon            218..306
                     /gene="Zfp14"
                     /gene_synonym="4732429I09Rik; Krox-9; mKIAA1559; Zfp-14"
                     /inference="alignment:Splign:2.1.0"
     CDS             292..1797
                     /gene="Zfp14"
                     /gene_synonym="4732429I09Rik; Krox-9; mKIAA1559; Zfp-14"
                     /note="zinc finger protein Krox-9"
                     /codon_start=1
                     /product="zinc finger protein 14"
                     /protein_id="NP_035878.1"
                     /db_xref="CCDS:CCDS39875.1"
                     /db_xref="GeneID:243906"
                     /db_xref="MGI:MGI:99160"
                     /translation="MALAQGLVTFGDVAVDFSQEEWEFLDPAQKNLYRDVMWETYSNF
                     ISLDLESRFKTDTSSSDKGICEVYSLQWELIEKIKNLSPQGSGLSDDQECKHKTGLQK
                     EPQEGYFGQLKITSEKVTYEKHSFLSEYQRVQNGEKFYECKECRKTFIRRSTLSQHLR
                     IHTGEKPYKCKECGQPFRQRAHLIRHHKLHTGEKPYECKDCGKAFTVLQELTQHQRLH
                     TGEKPYECKECGKAFRVHQQLARHQRIHTGEKPYECKECGKTFRQCTHLTRHQRLHTS
                     EKLYECKECGKAFVCGPDLRVHQKIHFGEKPYACKDCGKSFRICQQLTVHQSIHTGEK
                     PYECKECGKTFRLRQQLVRHQRIHTHERPYECLECWKTFSSYSQLISHQSIHVGERPY
                     ECEECGKAFRLLSQLTQHQSIHTGEKPYECQECRKPFRLLSQLTQHRSIHTGEKPYEC
                     KDCGKAFRLYSFLSQHQRIHTGEKPYKCKECKKAFRQHSHLTQHQKIHSGT"
     exon            307..433
                     /gene="Zfp14"
                     /gene_synonym="4732429I09Rik; Krox-9; mKIAA1559; Zfp-14"
                     /inference="alignment:Splign:2.1.0"
     exon            434..3491
                     /gene="Zfp14"
                     /gene_synonym="4732429I09Rik; Krox-9; mKIAA1559; Zfp-14"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2779..2784
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp14"
                     /gene_synonym="4732429I09Rik; Krox-9; mKIAA1559; Zfp-14"
                     /note="hexamer: AATAAA"
     polyA_site      2804
                     /gene="Zfp14"
                     /gene_synonym="4732429I09Rik; Krox-9; mKIAA1559; Zfp-14"
                     /note="major polyA site"
     regulatory      2937..2942
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp14"
                     /gene_synonym="4732429I09Rik; Krox-9; mKIAA1559; Zfp-14"
                     /note="hexamer: ATTAAA"
     polyA_site      2959
                     /gene="Zfp14"
                     /gene_synonym="4732429I09Rik; Krox-9; mKIAA1559; Zfp-14"
                     /note="major polyA site"
ORIGIN      
        1 aggcctctgc gcagcatcct tccggctgct tagcgccggt ccgctctgag agcagaagcc
       61 aggagaaggt gtctgattcc caggaactgg agttatagac ggtcgtgaaa caccattgct
      121 ggggttcgaa ctcaggcctt tatgtgttga ggccagccct ctccctctga gccttgtctc
      181 caggagtctt ctgctttgga gcctcacgag gagagagcgt tgcttgttga cccccagttt
      241 atcacaaaga aatactgaaa agagccgacc ggttcctgca gttctaacac tatggccctg
      301 gctcagggtt tagtgacgtt tggggatgtg gctgtggatt tctctcagga ggagtgggaa
      361 ttcctggacc ctgctcagaa gaacctgtac agggatgtga tgtgggagac ctatagcaat
      421 tttatttcac tggatttgga gtctagattc aagaccgata cttcatcttc agacaagggc
      481 atttgtgaag tatattcgtt acagtgggag ttgattgaga aaattaaaaa cctaagccct
      541 cagggttctg gtcttagtga tgatcaggaa tgtaaacaca agactgggct acaaaaggaa
      601 ccgcaggagg gttattttgg gcagttgaaa attacctctg aaaaagtcac atatgaaaag
      661 cacagtttcc tttctgagta ccagagagtt cagaatggag aaaagttcta tgaatgtaaa
      721 gagtgtagga agacctttat ccgccgctca acgcttagtc agcacttgag gatccacacc
      781 ggcgagaaac cttacaaatg caaggagtgt gggcaaccct tcagacagcg ggcgcacctt
      841 atccgacatc acaaacttca caccggtgag aagccctatg agtgtaagga ctgtgggaag
      901 gcctttacag tgctccagga actcacacag caccagcgtc ttcacactgg tgagaagccg
      961 tacgaatgca aggaatgtgg aaaggccttc cgggtccatc agcagctggc tcggcatcag
     1021 aggattcaca ctggggaaaa gccctatgag tgcaaggagt gtgggaagac cttcagacag
     1081 tgcacacacc ttacccgaca ccagagactt cacacttctg agaaactcta tgaatgtaag
     1141 gagtgtggga aagccttcgt gtgtggccca gaccttcgag tacatcagaa aatccacttt
     1201 ggtgagaagc cctatgcctg taaggactgt ggtaagtcct tcagaatatg ccaacagctg
     1261 accgtccacc agagtattca cactggggag aaaccctatg aatgtaagga atgtgggaag
     1321 accttcagat tgaggcagca gcttgttcgc catcagagaa tccataccca cgagagaccc
     1381 tatgagtgtc tggaatgctg gaagaccttc agtagctact cccagctgat ttcacatcag
     1441 agcattcatg ttggggagag accgtacgag tgtgaagagt gtgggaaggc cttccggctg
     1501 ctctcgcagc tcactcagca ccagagcatc catacaggcg agaagcctta tgaatgccag
     1561 gagtgtagaa aacccttccg gctgttgtca cagctcactc agcaccggag catccacacc
     1621 ggcgagaagc cttatgaatg caaggactgt ggcaaggctt ttagacttta ttcatttctt
     1681 tctcagcacc agaggatcca cactggtgag aagccctaca aatgtaagga gtgtaagaag
     1741 gccttcagac agcactcaca cctgacccag caccagaaga tccacagtgg aacctgacaa
     1801 gctctacacc aagttgtaac atgtcaggaa gtccgttttt aagaataatt tattttgtgc
     1861 ttgtaagtca gcataaataa gactgtgttg ctttaaaagc ccaccatccc cacttaaatg
     1921 ttacatttct tcagcaaatt cccatgaaag aattttgatg aatgtaggga aacgtttagc
     1981 ctcatctgtt atcatctaca tctcaccact ctcttccagt gtgacactgg acaggaccct
     2041 aagcattaat gccttgtttt gctcactgtc aaaatggtga caatagcacc tacacatatt
     2101 atttatcatt atgtaacaaa ttaaatagaa aaacagtaga ttaaataata cacttgtatt
     2161 atctaaaaat ttctatagat caagagtcca ggtatgcctt agttgggtct ttgaggtttc
     2221 agctaaggct ggctcccatc cgaaagctta gctagagaag gatccacatt ggagggaaca
     2281 ggttagacac ctgaattcat ttccttaaga gctgatccac tgggattctc agtttctgga
     2341 tggccattgg ctggaagatg agtgaagctc ctagccatat tggctgtcca gtgtggctgc
     2401 tgctctaatg atactgcaca agccaagaaa ggtggctgct agcaggatgg aggccagcta
     2461 gccagactga cgtgataatc tgtgccgtct aatcacagaa ggaacatcca gtcattttac
     2521 cacattctac tggtaaaatg gagttatcag accagcttac tccagaagtc tcgtgaaatt
     2581 gaatgtcaca aggaggctgg tgagtgaggc ccagggtaga gcccacctgc tgtactgcac
     2641 aacagcactg acttaaggat aaagtagtta acacttgacc aactagcagt catggtagca
     2701 tgtatcatac aataacgtct gtaattctta ctgccagtat tgtcaattca tgtgaaagga
     2761 agatgatccc atggaagtaa taaatgtaga aatgcctcct ttcacatctc tgcatttata
     2821 aacctcaaca taatttctcc tgggtaagac ctaggaaatt ataggaaatg ggagattttt
     2881 gtcacttgag caaaaacttc atgttgaaag gagactgagt ttcatgaatg tgtgttatta
     2941 aaacttaact attaaggaat ccgaggaaat gacttcttca catttcaaaa aagcagctca
     3001 tttagaatcc cttctctgac caaattcatg tttaatcacg cagtttcaag gatagctaac
     3061 ataaaggaca actagcagct tagggatctc attgttatgc acacacatat gtaagtattg
     3121 gggccacgga agtgcctgtg tggttaaagt gcttgctgtg taagcatgag gacccaactt
     3181 tggatcccca gaactcaagt taactgccag gtagatgtag tggctcactt gtaattccag
     3241 cctctggaga tagagaccag atatccaaag caagatggct agccaaacta tatctagcta
     3301 tatcggcgag ctctgggttg gattgagagc ccctgcccca gtgcatacag tggaagagtg
     3361 aatggacatg gttcctcaga taacctagga tctccacatg cacctgggca caagtccact
     3421 gcacacatac aaacagaaat cacacaaata aataccgtgc acacacaaat aaataaagaa
     3481 gctttatagt c
//
