LOCUS       NM_028379               1363 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus zinc finger, DHHC domain containing 4 (Zdhhc4),
            transcript variant 1, mRNA.
ACCESSION   NM_028379
VERSION     NM_028379.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1363)
  AUTHORS   Wang,J., Hao,J.W., Wang,X., Guo,H., Sun,H.H., Lai,X.Y., Liu,L.Y.,
            Zhu,M., Wang,H.Y., Li,Y.F., Yu,L.Y., Xie,C., Wang,H.R., Mo,W.,
            Zhou,H.M., Chen,S., Liang,G. and Zhao,T.J.
  TITLE     DHHC4 and DHHC5 Facilitate Fatty Acid Uptake by Palmitoylating and
            Targeting CD36 to the Plasma Membrane
  JOURNAL   Cell Rep 26 (1), 209-221 (2019)
   PUBMED   30605677
REFERENCE   2  (bases 1 to 1363)
  AUTHORS   Hald,J., Galbo,T., Rescan,C., Radzikowski,L., Sprinkel,A.E.,
            Heimberg,H., Ahnfelt-Ronne,J., Jensen,J., Scharfmann,R.,
            Gradwohl,G., Kaestner,K.H., Stoeckert,C. Jr., Jensen,J.N. and
            Madsen,O.D.
  TITLE     Pancreatic islet and progenitor cell surface markers with cell
            sorting potential
  JOURNAL   Diabetologia 55 (1), 154-165 (2012)
   PUBMED   21947380
REFERENCE   3  (bases 1 to 1363)
  AUTHORS   Guo,G., Huss,M., Tong,G.Q., Wang,C., Li Sun,L., Clarke,N.D. and
            Robson,P.
  TITLE     Resolution of cell fate decisions revealed by single-cell gene
            expression analysis from zygote to blastocyst
  JOURNAL   Dev Cell 18 (4), 675-685 (2010)
   PUBMED   20412781
REFERENCE   4  (bases 1 to 1363)
  AUTHORS   Hoffman,B.G., Zavaglia,B., Witzsche,J., Ruiz de Algara,T.,
            Beach,M., Hoodless,P.A., Jones,S.J., Marra,M.A. and Helgason,C.D.
  TITLE     Identification of transcripts with enriched expression in the
            developing and adult pancreas
  JOURNAL   Genome Biol 9 (6), R99 (2008)
   PUBMED   18554416
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB868748.1, AK013609.1 and BE853198.1.
            
            On Jan 4, 2012 this sequence version replaced NM_028379.4.
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC019523.1, AK013609.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-147               BB868748.1         2-148
            148-1342            AK013609.1         135-1329
            1343-1363           BE853198.1         1-21                c
FEATURES             Location/Qualifiers
     source          1..1363
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 82.08 cM"
     gene            1..1363
                     /gene="Zdhhc4"
                     /gene_synonym="1810021D01Rik; 2900029I10Rik; DHHC-4"
                     /note="zinc finger, DHHC domain containing 4"
                     /db_xref="GeneID:72881"
                     /db_xref="MGI:MGI:1920131"
     exon            1..73
                     /gene="Zdhhc4"
                     /gene_synonym="1810021D01Rik; 2900029I10Rik; DHHC-4"
                     /inference="alignment:Splign:2.1.0"
     exon            74..253
                     /gene="Zdhhc4"
                     /gene_synonym="1810021D01Rik; 2900029I10Rik; DHHC-4"
                     /inference="alignment:Splign:2.1.0"
     exon            254..378
                     /gene="Zdhhc4"
                     /gene_synonym="1810021D01Rik; 2900029I10Rik; DHHC-4"
                     /inference="alignment:Splign:2.1.0"
     CDS             262..1293
                     /gene="Zdhhc4"
                     /gene_synonym="1810021D01Rik; 2900029I10Rik; DHHC-4"
                     /EC_number="2.3.1.225"
                     /note="isoform 1 is encoded by transcript variant 1;
                     probable palmitoyltransferase ZDHHC4; zinc finger DHHC
                     domain-containing protein 4"
                     /codon_start=1
                     /product="palmitoyltransferase ZDHHC4 isoform 1"
                     /protein_id="NP_082655.1"
                     /db_xref="CCDS:CCDS19840.1"
                     /db_xref="GeneID:72881"
                     /db_xref="MGI:MGI:1920131"
                     /translation="MDFLVLFLFYLAFLLICVVLICIFTKSQRLKAVVLGGAQVCSRV
                     IPQCLQRAVQTLLHQLFHTRHPTFIVLHLLLQGLVYAEYTCEVFGYCRELEFSLPYLL
                     LPYVLLSVNLVFFTLTCAANPGTITKANESFLLQVYKFDDVMFPKNSRCPTCDLRKPA
                     RSKHCRLCDRCVHRFDHHCVWVNNCIGAWNTRYFLIYLLTLTASAATIATVTAAFLLR
                     LVTVSDLYQETYLDDVGHFQAVDTVFLIQHLFLAFPRIVFLLGFVIVLSMLLAGYLCF
                     ALYLAATNQTTNEWYKGDWAWCQRWPLVAWSPSAEPRIHQNIHSHGFRSNLREIFLPA
                     TPSYKKKEK"
     exon            379..452
                     /gene="Zdhhc4"
                     /gene_synonym="1810021D01Rik; 2900029I10Rik; DHHC-4"
                     /inference="alignment:Splign:2.1.0"
     exon            453..631
                     /gene="Zdhhc4"
                     /gene_synonym="1810021D01Rik; 2900029I10Rik; DHHC-4"
                     /inference="alignment:Splign:2.1.0"
     exon            632..757
                     /gene="Zdhhc4"
                     /gene_synonym="1810021D01Rik; 2900029I10Rik; DHHC-4"
                     /inference="alignment:Splign:2.1.0"
     exon            758..1002
                     /gene="Zdhhc4"
                     /gene_synonym="1810021D01Rik; 2900029I10Rik; DHHC-4"
                     /inference="alignment:Splign:2.1.0"
     exon            1003..1346
                     /gene="Zdhhc4"
                     /gene_synonym="1810021D01Rik; 2900029I10Rik; DHHC-4"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1316..1321
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zdhhc4"
                     /gene_synonym="1810021D01Rik; 2900029I10Rik; DHHC-4"
                     /note="hexamer: AATACA"
     polyA_site      1346
                     /gene="Zdhhc4"
                     /gene_synonym="1810021D01Rik; 2900029I10Rik; DHHC-4"
                     /note="major polyA site"
ORIGIN      
        1 ggacgcgccg gaagtcttgg ggagcgctcc gctggggtcc gccggcagcg gcggacggtt
       61 ggcccggttt gggccggttc cagcctcctg gaacaaccat gtcgccagtt ttgcgcgtgc
      121 caaattcacg gcgctgccca agcggagctg ctatctgaat tctccttgga tgtggcaaag
      181 ggaaatgaac gcaaaaggtg ccgctggaag tgtccgacct agagaaatat gtagaccgga
      241 gccctgttac cttcctccag catggacttc ctggttctct tcttgttcta cttggccttc
      301 ttattgattt gtgttgtcct gatctgcatc ttcacaaaaa gccagcgttt gaaggccgtg
      361 gtccttggag gagcacaggt gtgctccagg gtaatcccgc agtgcctcca gagggccgtg
      421 cagacgcttc ttcatcagct cttccacaca cgccacccca ccttcatcgt cttgcacctg
      481 ctcttgcaag ggctagtgta tgcagaatac acctgcgagg tcttcggcta ttgccgggag
      541 ctggagttct ctctgcctta ccttctcctg ccctatgtgc tgctaagcgt gaacctggtg
      601 ttcttcaccc tgacttgtgc cgccaatcct ggtaccatca ctaaagcaaa cgaatcattt
      661 cttctgcaag tctataaatt cgatgatgtg atgtttccaa agaactcgag gtgccccact
      721 tgcgatttaa ggaaaccagc ccgctccaag cactgcaggt tgtgtgaccg ctgtgtgcac
      781 cggttcgacc atcactgtgt ttgggtgaac aactgcatcg gggcctggaa caccaggtac
      841 ttcctcattt acctcctgac gctgacggct tctgctgcca ccatagccac cgtgactgct
      901 gcctttctgc tccgcctagt gacagtgtct gatctctacc aggaaactta cctagatgac
      961 gtggggcatt tccaggctgt ggacactgtc tttcttattc agcatctgtt cctggcattt
     1021 ccaaggattg tcttcctact gggctttgtc atcgttttga gcatgctcct ggctggctac
     1081 ttgtgctttg ctctgtacct ggctgccacc aaccagacca caaatgaatg gtataaaggc
     1141 gactgggcct ggtgccagcg ctggcctctg gtggcttggt ccccatcagc tgagccccgg
     1201 atccaccaga acattcactc ccacgggttt aggagcaacc ttcgagagat ctttctacct
     1261 gctaccccca gttacaagaa aaaggagaaa tagagcggaa gtgccctgcc ttttaaatac
     1321 agtgcacacc tatttgtaca catggaaaaa aaaaaaaaaa aaa
//
