LOCUS       NM_026917               6988 bp    mRNA    linear   ROD 12-JUN-2024
DEFINITION  Mus musculus zinc finger, DHHC domain containing 3 (Zdhhc3),
            transcript variant 2, mRNA.
ACCESSION   NM_026917
VERSION     NM_026917.6
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6988)
  AUTHORS   Yu,T., Hou,D., Zhao,J., Lu,X., Greentree,W.K., Zhao,Q., Yang,M.,
            Conde,D.G., Linder,M.E. and Lin,H.
  TITLE     NLRP3 Cys126 palmitoylation by ZDHHC7 promotes inflammasome
            activation
  JOURNAL   Cell Rep 43 (4), 114070 (2024)
   PUBMED   38583156
REFERENCE   2  (bases 1 to 6988)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 6988)
  AUTHORS   Baldwin,T.A., Teuber,J.P., Kuwabara,Y., Subramani,A., Lin,S.J.,
            Kanisicak,O., Vagnozzi,R.J., Zhang,W., Brody,M.J. and
            Molkentin,J.D.
  TITLE     Palmitoylation-dependent regulation of cardiomyocyte Rac1 signaling
            activity and minor effects on cardiac hypertrophy
  JOURNAL   J Biol Chem 299 (12), 105426 (2023)
   PUBMED   37926281
REFERENCE   4  (bases 1 to 6988)
  AUTHORS   Cui,X., Liu,H., Shi,T., Zhao,Q., Li,F., Lv,W., Yu,C., Huang,H.,
            Tang,Q.Q. and Pan,D.
  TITLE     IFI27 Integrates Succinate and Fatty Acid Oxidation to Promote
            Adipocyte Thermogenic Adaption
  JOURNAL   Adv Sci (Weinh) 10 (28), e2301855 (2023)
   PUBMED   37544897
  REMARK    GeneRIF: IFI27 Integrates Succinate and Fatty Acid Oxidation to
            Promote Adipocyte Thermogenic Adaption.
REFERENCE   5  (bases 1 to 6988)
  AUTHORS   Wang,S., Mott,K.R., Cilluffo,M., Kilpatrick,C.L., Murakami,S.,
            Ljubimov,A.V., Kousoulas,K.G., Awasthi,S., Luscher,B. and Ghiasi,H.
  TITLE     The Absence of DHHC3 Affects Primary and Latent Herpes Simplex
            Virus 1 Infection
  JOURNAL   J Virol 92 (4), e01599-17 (2018)
   PUBMED   29187538
  REMARK    GeneRIF: Absence of zinc finger protein GODZ affects primary and
            latent infection, as well as reactivation, in ocularly infected
            mice. The reduced virus infectivity is due to the absence of the
            GODZ interaction with HSV-1 UL20. These results strongly suggest
            that binding of UL20 to GODZ promotes virus infectivity in vitro
            and viral pathogenesis in vivo.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 6988)
  AUTHORS   Fang,C., Deng,L., Keller,C.A., Fukata,M., Fukata,Y., Chen,G. and
            Luscher,B.
  TITLE     GODZ-mediated palmitoylation of GABA(A) receptors is required for
            normal assembly and function of GABAergic inhibitory synapses
  JOURNAL   J Neurosci 26 (49), 12758-12768 (2006)
   PUBMED   17151279
  REMARK    GeneRIF: GODZ-mediated palmitoylation of GABA(A) receptor gamma 2
            subunit, and possibly other substrates, contributes selectively to
            the formation and normal function of GABAergic inhibitory synapses.
REFERENCE   7  (bases 1 to 6988)
  AUTHORS   Hayashi,T., Rumbaugh,G. and Huganir,R.L.
  TITLE     Differential regulation of AMPA receptor subunit trafficking by
            palmitoylation of two distinct sites
  JOURNAL   Neuron 47 (5), 709-723 (2005)
   PUBMED   16129400
REFERENCE   8  (bases 1 to 6988)
  AUTHORS   Fukata,M., Fukata,Y., Adesnik,H., Nicoll,R.A. and Bredt,D.S.
  TITLE     Identification of PSD-95 palmitoylating enzymes
  JOURNAL   Neuron 44 (6), 987-996 (2004)
   PUBMED   15603741
REFERENCE   9  (bases 1 to 6988)
  AUTHORS   Keller,C.A., Yuan,X., Panzanelli,P., Martin,M.L., Alldred,M.,
            Sassoe-Pognetto,M. and Luscher,B.
  TITLE     The gamma2 subunit of GABA(A) receptors is a substrate for
            palmitoylation by GODZ
  JOURNAL   J Neurosci 24 (26), 5881-5891 (2004)
   PUBMED   15229235
  REMARK    GeneRIF: GODZ-mediated palmitoylation is a novel posttranslational
            modification that is selective for gamma-subunit-containing GABA(A)
            receptor subtypes, a mechanism that may be important for regulated
            trafficking of these receptors in the secretory pathway.
REFERENCE   10 (bases 1 to 6988)
  AUTHORS   Mu,X., Zhao,S., Pershad,R., Hsieh,T.F., Scarpa,A., Wang,S.W.,
            White,R.A., Beremand,P.D., Thomas,T.L., Gan,L. and Klein,W.H.
  TITLE     Gene expression in the developing mouse retina by EST sequencing
            and microarray analysis
  JOURNAL   Nucleic Acids Res 29 (24), 4983-4993 (2001)
   PUBMED   11812828
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC134248.3 and AC133650.4.
            
            On Sep 4, 2019 this sequence version replaced NM_026917.5.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC052464.1, AK080541.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164143 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-199               AC134248.3         53815-54013         c
            200-529             AC133650.4         162655-162984       c
            530-654             AC133650.4         151424-151548       c
            655-751             AC133650.4         146606-146702       c
            752-833             AC133650.4         145937-146018       c
            834-964             AC133650.4         142743-142873       c
            965-6988            AC133650.4         134690-140713       c
FEATURES             Location/Qualifiers
     source          1..6988
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 73.66 cM"
     gene            1..6988
                     /gene="Zdhhc3"
                     /gene_synonym="1110020O22Rik; 1810006O10Rik;
                     2210017C02Rik; DHHC-3; GODZ; Gramp1; Zfp373"
                     /note="zinc finger, DHHC domain containing 3"
                     /db_xref="GeneID:69035"
                     /db_xref="MGI:MGI:1926134"
     exon            1..199
                     /gene="Zdhhc3"
                     /gene_synonym="1110020O22Rik; 1810006O10Rik;
                     2210017C02Rik; DHHC-3; GODZ; Gramp1; Zfp373"
                     /inference="alignment:Splign:2.1.0"
     exon            200..529
                     /gene="Zdhhc3"
                     /gene_synonym="1110020O22Rik; 1810006O10Rik;
                     2210017C02Rik; DHHC-3; GODZ; Gramp1; Zfp373"
                     /inference="alignment:Splign:2.1.0"
     CDS             224..1123
                     /gene="Zdhhc3"
                     /gene_synonym="1110020O22Rik; 1810006O10Rik;
                     2210017C02Rik; DHHC-3; GODZ; Gramp1; Zfp373"
                     /EC_number="2.3.1.225"
                     /note="isoform 2 is encoded by transcript variant 2;
                     palmitoyltransferase ZDHHC3; GABA-A receptor-associated
                     membrane protein 1; golgi-specific DHHC zinc finger
                     protein; zinc finger DHHC domain-containing protein 3;
                     acyltransferase ZDHHC3"
                     /codon_start=1
                     /product="palmitoyltransferase ZDHHC3 isoform 2"
                     /protein_id="NP_081193.2"
                     /db_xref="CCDS:CCDS23654.1"
                     /db_xref="GeneID:69035"
                     /db_xref="MGI:MGI:1926134"
                     /translation="MMLIPTHHFRDIERKPEYLQPEKCAPPPFPGPAGAMWFIRDGCG
                     IACAIVTWFLVLYAEFVVLFVMLVPSRDYAYSIINGIVFNLLAFLALASHCRAMLTDP
                     GAVPKGNATKEFIESLQLKPGQVVYKCPKCCSIKPDRAHHCSVCKRCIRKMDHHCPWV
                     NNCVGENNQKYFVLFTMYIALISLHALIMVGFHFLHCFEEDWTKCSSFSPPTTVILLI
                     LLCFEALLFLIFTSVMFGTQVHSICTDETGIEQLKKEERRWAKKTKWMNMKAVFGHPF
                     SLGWASPFATPDQGKADPYQYVV"
     exon            530..654
                     /gene="Zdhhc3"
                     /gene_synonym="1110020O22Rik; 1810006O10Rik;
                     2210017C02Rik; DHHC-3; GODZ; Gramp1; Zfp373"
                     /inference="alignment:Splign:2.1.0"
     exon            655..751
                     /gene="Zdhhc3"
                     /gene_synonym="1110020O22Rik; 1810006O10Rik;
                     2210017C02Rik; DHHC-3; GODZ; Gramp1; Zfp373"
                     /inference="alignment:Splign:2.1.0"
     exon            752..833
                     /gene="Zdhhc3"
                     /gene_synonym="1110020O22Rik; 1810006O10Rik;
                     2210017C02Rik; DHHC-3; GODZ; Gramp1; Zfp373"
                     /inference="alignment:Splign:2.1.0"
     exon            834..964
                     /gene="Zdhhc3"
                     /gene_synonym="1110020O22Rik; 1810006O10Rik;
                     2210017C02Rik; DHHC-3; GODZ; Gramp1; Zfp373"
                     /inference="alignment:Splign:2.1.0"
     exon            965..6988
                     /gene="Zdhhc3"
                     /gene_synonym="1110020O22Rik; 1810006O10Rik;
                     2210017C02Rik; DHHC-3; GODZ; Gramp1; Zfp373"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2434..2439
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zdhhc3"
                     /gene_synonym="1110020O22Rik; 1810006O10Rik;
                     2210017C02Rik; DHHC-3; GODZ; Gramp1; Zfp373"
                     /note="hexamer: AATAAA"
     polyA_site      2454
                     /gene="Zdhhc3"
                     /gene_synonym="1110020O22Rik; 1810006O10Rik;
                     2210017C02Rik; DHHC-3; GODZ; Gramp1; Zfp373"
                     /note="major polyA site"
     regulatory      5112..5117
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zdhhc3"
                     /gene_synonym="1110020O22Rik; 1810006O10Rik;
                     2210017C02Rik; DHHC-3; GODZ; Gramp1; Zfp373"
                     /note="hexamer: AATACA"
     polyA_site      5143
                     /gene="Zdhhc3"
                     /gene_synonym="1110020O22Rik; 1810006O10Rik;
                     2210017C02Rik; DHHC-3; GODZ; Gramp1; Zfp373"
     regulatory      6592..6597
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zdhhc3"
                     /gene_synonym="1110020O22Rik; 1810006O10Rik;
                     2210017C02Rik; DHHC-3; GODZ; Gramp1; Zfp373"
                     /note="hexamer: GATAAA"
     polyA_site      6613
                     /gene="Zdhhc3"
                     /gene_synonym="1110020O22Rik; 1810006O10Rik;
                     2210017C02Rik; DHHC-3; GODZ; Gramp1; Zfp373"
     regulatory      6960..6965
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zdhhc3"
                     /gene_synonym="1110020O22Rik; 1810006O10Rik;
                     2210017C02Rik; DHHC-3; GODZ; Gramp1; Zfp373"
                     /note="hexamer: AATAAA"
     polyA_site      6988
                     /gene="Zdhhc3"
                     /gene_synonym="1110020O22Rik; 1810006O10Rik;
                     2210017C02Rik; DHHC-3; GODZ; Gramp1; Zfp373"
ORIGIN      
        1 agcccgcgcg gtggccgctc ccgcagccgc ggctgccgcc accgcctgga gctccatggg
       61 cttctccttc gcaccgcccc gtgtgaggcc gagtccggca agccgtggcg ccgggtgccc
      121 gtgccatcgc ggacgctggc ggctgggccc cggggcagca gcaggcggcg cgggactgct
      181 agctgcctcc agattgacga tgccagtatg gacagaatag cttatgatgc ttatccccac
      241 ccatcacttc cgagacattg agcggaaacc agagtacctc cagccagaga agtgtgcccc
      301 acctcccttc cctggtcctg cgggagccat gtggtttatc cgagatggct gtggcattgc
      361 ttgtgccatt gtcacctggt ttctggtcct ctatgcggag tttgtagtcc tctttgtcat
      421 gctggttcca tcccgagact acgcgtacag catcatcaac ggaattgtgt tcaacctgct
      481 ggccttcttg gccctggcct cccactgccg ggccatgctg acggaccccg gggcagtgcc
      541 caaaggaaat gccactaaag agttcatcga gagccttcag ctgaagcctg ggcaggtggt
      601 gtacaagtgt cccaagtgct gcagcatcaa gcccgaccgg gcacaccact gcagtgtttg
      661 taagcggtgc attcgcaaga tggatcacca ctgtccttgg gtcaacaact gtgtcggcga
      721 gaacaaccag aagtactttg tcctattcac aatgtacata gctctcattt ccttgcacgc
      781 cctcatcatg gtgggattcc acttcctgca ttgctttgaa gaagactgga caaagtgcag
      841 ctccttctcg ccgcccacca cagtcatcct gctcatcctg ctgtgctttg aggccctgct
      901 cttcctcatt ttcacatcag tgatgtttgg gacccaagta cactccatct gcacagatga
      961 gacgggcata gaacaattga aaaaggaaga gagaagatgg gctaaaaaaa caaaatggat
     1021 gaacatgaaa gccgtgtttg gccacccttt ctctctaggc tgggccagcc cctttgccac
     1081 accagaccaa gggaaggcag acccgtacca gtatgtggtc tgaaggaccc tgaccagcat
     1141 tgccactcag accacatcat ggcacctccc atccgctctt gtgaatgttt aggccaaaac
     1201 tcttaaaact tttttatgtc ttcagaaaaa tggctgagca ttgcagagaa aaaaaaagtc
     1261 ctcatgtttt atttttaaaa aaaaaatcat cctttcaatt ttttgatgac tggagctgct
     1321 cttttccctt ttaaaatcac ttctctggcc tctgtttcct ctctgctctg tcagcatgac
     1381 taacgtcgag ggtgctgctc aggccctgcc ccttctacta attgaatgcc cctgatgctg
     1441 tgtatggatg aactggccca gtaggaaagc caagagggcc ctgacctcct cctgcccaca
     1501 gggcagcact ggcgcccgca ggactcagaa cctcttcgaa gataatgcta accccttgaa
     1561 gcctaaggat gaaaagattg ggctggagcc atcataaggg tccttggtgc agtggcctcc
     1621 tgcccaagtg gacagttcgc ctcagtttca gaaatcgatg ggtgtgggtg tacagaatga
     1681 cttgggggag gtgggagagg taaaggggcc tttgtattct gaatcagcaa ttatgtcact
     1741 ctggcttttg ggaagactat gaaagagatg tttcccagtt caaaaatgcc ttatacaatc
     1801 acaagaggaa aacaatttca ggcaagctac aacaactttc taccccagtt cccgcccttt
     1861 cccagcaaga tgtcagtcat tctgagggaa acagacaacc tcctgtcagg atcatctcag
     1921 ttttaaccgt gtcatgagca tagactttct ggagttgaaa gtcctccaga tgtgcacaga
     1981 cctgtgtctt atgtgtgttt agtctgggaa gtggttgtag atgttaggta acattcttag
     2041 agttgccagg tagcccctac tcacctgctt ctcagcctgc tacacagaca agctttccca
     2101 tcagcaggta ctgctaagca aagtcacaca gggaagagct ggtcttgagc tagggaggaa
     2161 ccaggggatg taggaggtgc taagagaaga ctgctcttga accctacagc cacgtggaac
     2221 ctgagcacca tgaagtcccc caaaccagtg ggttttaaag caatcaccac aaaactccct
     2281 ttttagcttt tgcttggggt gggggtgggg ataaggtttt tcattctagt tgtgggtagg
     2341 aagaaagtta atgtagccct gtggtttttc agaagtcggt gggacgttct gcctcttccc
     2401 aactctgtca gtgcttccac atggaaacaa tgcaataaac cttttccaaa cctgcttctg
     2461 ctctgctctc tccccacggc ctgtgcagaa gggcaggtgg tgtcaggctg caggctgagg
     2521 gagtttagtt ttgttcttaa aggctatgga tggcctttct gcaggcagaa ttctctgcat
     2581 gagttgctgg tgagggtgcc ctatggctcc aagaggtcag tctttctgga gtctagggcc
     2641 agagcctgcc cagcagagag caaaagctgt gccaacagaa agtgcctagc atctataccc
     2701 acagtgcgag gtgctgtttt tctggggggt tcttgttgat ggtatctagt gatgacagat
     2761 gaggcaacac tgaggaactg gccacctccc ctacctccgt aggctttgat ttgcctcggc
     2821 tgtgccgttt aggctgagat cctgggtgtg tgctcatgtg gagttttaca cataactata
     2881 tatcgacata gataggttta gatgaagttc atagcatttg ttctccaggt gcctttgaaa
     2941 ttttgtttat ttatctcttg gtttatatga aagaggtgtg gcctgttcca ggttcagcag
     3001 gttagaaggg tccagctgtc cagccttgct cgaatactca ggttagatct gctgtggcaa
     3061 agagcagcta cactgcacac tgcagctatg gttctgttgt caacatattc atattctctc
     3121 tctctctccc tctccccccc ccccaagact ggaactaagg aaatagcctt tagcctttaa
     3181 gggcattttg tgaatggctc tagcttttgc tatggggttt cacagtagat ggcactgcag
     3241 gaatttgaat cctgaaatta aagctcacac tctaaatagg catgcgacca gcttactgcc
     3301 caggcccttg taagtctccc tctgcattat tacaaccaaa ggctgcaaag tggaggtcct
     3361 tagtgctcaa actacagcaa aaaggcctca agacaggact accctagggt ggcctgtgag
     3421 taccattgca ttctctctga agccaggaga atttttctgt gagcacagta gtgaccaagg
     3481 ctgtgtgtca acaaatgact ctgtcctgag tcttctgatc cctttagatg gagtaaaagg
     3541 tctttctccg tggcctactg gaaagtgagc ctttgtcgcc catcttccag aatggtaact
     3601 gggtaatagg agtgaagaag acatggccag tagactgggt aacccacgta cttgtccatt
     3661 tcttcatgtc atatctgcat atttgcatga gcttggtgac atgtatacag tagaaatgtg
     3721 tgcccagtct ttccttaata ccattttacc tttgtaacac ttggacctta caagacttac
     3781 aggactaaag ggtagctagc ttttgctcat tctgactgaa ccactttgca tcctgatgag
     3841 agaaatcttc caaagaaggc aaattcccaa gtgcttatta aggaataccc atgcaagact
     3901 ggcatcacag acactccact gtagaagggt gggctcggac tatccatcca aactaagaag
     3961 ttctcagttt ctcttctttc aaaacaaagt ataccagttc caaagggtga actagccaag
     4021 ggacacaagc agttccagca aaaaaggagg gccagtggtt tttttgcaca agctcagggc
     4081 ctcagaattt atagggatgg ggcttcaggt tagccctgct gccactgctg gtaggtacag
     4141 caaactagtt cctgggatgt tatatctgag gccagcatgc tcccactgat gaaccactga
     4201 ctccttccac tctgttacct gtgacctctt taaacatgtc atctgagttt gtcttgacca
     4261 atggcacctt tactgaagag ccagcaagat gagggtagaa ccaaggaacc aaccttcctg
     4321 tgaggagtgt gcagtgagtt ctccagacca cacagtgttt gagcaaccca accactggca
     4381 gtgttctggt cttcattttc cactgtagct tcactgacgg ggccaactgg ttatctgaag
     4441 ccaagtatgg aggagcacgt gtgcaaaccc agcgagttcg gaactggagg caagagggtc
     4501 agttcaaggt catcctttgc catacagaga gctcaggatt aacctgtggt acatgagacc
     4561 ctacctcaaa aaacaaagac ttcataaaga gccaggtcta tgtgtctgta gacccaacac
     4621 tcagcaagtt agggccagaa tatgccttaa gttcaggagt tcaagaccag cccaggcagc
     4681 acagtgagcc tctgtttaaa aaagaaaagg aaagaagcca ctgaaccgct tgttctccca
     4741 aacctggccc ttcaactccc ttctccctcc tctacgctcc cacggacaaa taaaaacaaa
     4801 ggaacgatga ctggtacttc taagatggca tgctagaaac cctctagggg aaaggcgcca
     4861 ttaactctct tgtggaataa aggacacctg gaattcttca gctggggtga tggagttcag
     4921 cacttgtcta acctcagtgt gtggtctctg tagaacatga tcacctactc tcatggtttc
     4981 tgtaagcact ggataaaaat ggaaggtaga atggtatggg cgggctttgg tttctgtgtg
     5041 tgtaacagct gcacaggagc tgtgattttt ccagtctggg tcaccaatgt ctgcccctgc
     5101 ccctttctta caatacatga ccgctgcgtg atacttcaga gtactttggt tgtgagtctg
     5161 tgcatcttct gggttgcaac aggaagacgt ttcgtgctgt gggctgcagt agaagggtat
     5221 ggagctgctg ctcgagagag ttggtatcat ctgaccagct ctccagagct tgctgtgggg
     5281 atgctggcca gcttatctgc tggcactggg gtcctattcc aggagtctca caagccctga
     5341 actgatgcct gtggtccctg ccacccttgg gagccttagg cctcacacat tcatgctggg
     5401 gtgttggtgc aatgttcacc ggtcagactc tacaggccgt tcaggtgagg ccgaggcctg
     5461 ctcacttgtg tcagtcactg ttcgcttgag cctgacatgg ctcacacctg tgaatctcag
     5521 gctgcagaac tttgccttct ggacaccttt aagtctacaa ctcttagaaa aagaagctct
     5581 ggggtctgtt ttatgcatca attttcttag attattttct ttccctgctc aaagctgaca
     5641 ctcctgatgt ctatatatat agctgctaag gaatgtgggc acacaggcca gttgatccta
     5701 acacaccact ttacagtggt aatcctgggc ttgctctgcc tctgcacctg actttgagac
     5761 ctacagagtg aggctttgtc agacaatggg gaaaacacct ggtggagaga aaaaaaagca
     5821 cttgtcctgc ttctgcataa ctttctgttt ttgttttttt gtttttgttt ttgttttttg
     5881 agacagggtt tctctgtaga gccctggctg tcctggaact cactttgtag accaggctgg
     5941 ccttgaactc agaaatctgc ctgcctctgc ctctaggatt aaaggtgtgc gccaccacgc
     6001 ctggcttctg cataactttc taaccaagct tgggctgctg tctcagcctc tcgggaactt
     6061 aatactgaca ccttcacaag gggtgtgtgt gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt
     6121 ctgtgtcagg acctgtgttc ctggcggtgg agggcatcat ctgcctgtct tcatgacctg
     6181 cagagactat taaaactctg gtcttagctg attcttgttc ttattacaaa aactaatgct
     6241 tgctccatgg tgaaaacatg aaatgtggac aagtccacag aaatacaccc catctgcaac
     6301 ggtaacagcc ccatgggggg tgtcctgtgc aaagtgcttc tccttaaggc aagacacagg
     6361 ttgcaggatg tcccagggtc atgcaaaaca tggtttctca gtgccacact tgcaacttat
     6421 agaactagtt acttagactg cgttgctgca cattccagtt ctcaatttat cattataact
     6481 cagtgtcaat tctgtcttgg gttctcttga acttctcatt gtaaaataat gtcagactta
     6541 taaaaatcag caaaattgta tatcttctga atgacattca gtgttaccaa agataaacat
     6601 cttacaacaa caacaacaac aaattccttt ctcttttaag aaagtaattt ggaaagaaaa
     6661 aggagggggt ggggaaaact tgcagtctcc atagtggtgc acacctgtag tcctagctgt
     6721 tcaagagact agggtgggaa gatcactgat tctcggagtt tgaggccagc ttgaactgtg
     6781 cggcagaccg aaacccattc tctccttaag aacaaaactc ttactgtcct ctacctcggg
     6841 ggagctttct ctacctgcct tttgtcttca gggattccac attctactac ttgtctctac
     6901 cccatttcta tcagttcctc agtcttaaat ttgtcatgac ctagattttt ttaattgaga
     6961 ataaattcat ataatgtaat acaaatca
//
