LOCUS       NM_001007460            5864 bp    mRNA    linear   ROD 12-FEB-2025
DEFINITION  Mus musculus zinc finger, DHHC domain containing 23 (Zdhhc23),
            transcript variant 1, mRNA.
ACCESSION   NM_001007460 XM_017317056 XM_285173 XM_358846
VERSION     NM_001007460.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5864)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 5864)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 5864)
  AUTHORS   Duncan,P.J., Bi,D., McClafferty,H., Chen,L., Tian,L. and
            Shipston,M.J.
  TITLE     S-Acylation controls functional coupling of BK channel pore-forming
            alpha-subunits and beta1-subunits
  JOURNAL   J Biol Chem 294 (32), 12066-12076 (2019)
   PUBMED   31213527
REFERENCE   4  (bases 1 to 5864)
  AUTHORS   Jones,M.R., Dilai,S., Lingampally,A., Chao,C.M., Danopoulos,S.,
            Carraro,G., Mukhametshina,R., Wilhelm,J., Baumgart-Vogt,E., Al
            Alam,D., Chen,C., Minoo,P., Zhang,J.S. and Bellusci,S.
  TITLE     A Comprehensive Analysis of Fibroblast Growth Factor Receptor 2b
            Signaling on Epithelial Tip Progenitor Cells During Early Mouse
            Lung Branching Morphogenesis
  JOURNAL   Front Genet 9, 746 (2019)
   PUBMED   30728831
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 5864)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   6  (bases 1 to 5864)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   7  (bases 1 to 5864)
  AUTHORS   Tian,L., McClafferty,H., Knaus,H.G., Ruth,P. and Shipston,M.J.
  TITLE     Distinct acyl protein transferases and thioesterases control
            surface expression of calcium-activated potassium channels
  JOURNAL   J Biol Chem 287 (18), 14718-14725 (2012)
   PUBMED   22399288
REFERENCE   8  (bases 1 to 5864)
  AUTHORS   Lau,N.C., Seto,A.G., Kim,J., Kuramochi-Miyagawa,S., Nakano,T.,
            Bartel,D.P. and Kingston,R.E.
  TITLE     Characterization of the piRNA complex from rat testes
  JOURNAL   Science 313 (5785), 363-367 (2006)
   PUBMED   16778019
REFERENCE   9  (bases 1 to 5864)
  AUTHORS   Fukata,M., Fukata,Y., Adesnik,H., Nicoll,R.A. and Bredt,D.S.
  TITLE     Identification of PSD-95 palmitoylating enzymes
  JOURNAL   Neuron 44 (6), 987-996 (2004)
   PUBMED   15603741
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC129306.5 and CT025520.10.
            
            On or before Feb 16, 2019 this sequence version replaced
            XM_017317056.1, NM_001007460.1.
            
            Transcript Variant: This variant (1) represents the longer
            transcript. Variants 1 and 2 both encode the same protein.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR10662773.767423.1,
                                           SRR7345562.1696414.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-351               AC129306.5         19798-20148
            352-620             AC129306.5         20431-20699
            621-1319            CT025520.10        309-1007
            1320-1487           CT025520.10        2909-3076
            1488-5864           CT025520.10        5062-9438
FEATURES             Location/Qualifiers
     source          1..5864
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 28.44 cM"
     gene            1..5864
                     /gene="Zdhhc23"
                     /gene_synonym="DHHC-23; Gm1751; Gm779; nidd"
                     /note="zinc finger, DHHC domain containing 23"
                     /db_xref="GeneID:332175"
                     /db_xref="MGI:MGI:2685625"
     exon            1..351
                     /gene="Zdhhc23"
                     /gene_synonym="DHHC-23; Gm1751; Gm779; nidd"
                     /inference="alignment:Splign:2.1.0"
     exon            352..620
                     /gene="Zdhhc23"
                     /gene_synonym="DHHC-23; Gm1751; Gm779; nidd"
                     /inference="alignment:Splign:2.1.0"
     CDS             478..1755
                     /gene="Zdhhc23"
                     /gene_synonym="DHHC-23; Gm1751; Gm779; nidd"
                     /EC_number="2.3.1.225"
                     /note="probable palmitoyltransferase ZDHHC23; zinc finger
                     DHHC domain-containing protein 23; DHHC-containing protein
                     11; nNOS-intereacting DHHC-containing Dem protein-L"
                     /codon_start=1
                     /product="palmitoyltransferase ZDHHC23"
                     /protein_id="NP_001007461.1"
                     /db_xref="CCDS:CCDS28180.1"
                     /db_xref="GeneID:332175"
                     /db_xref="MGI:MGI:2685625"
                     /translation="MKPVKKKKTEEPELEPLCCCEYIDRNGEKNHVAACLCDCQDLDE
                     GCDRWLTCQSLRPETCERITDTISDRLRIPWLRGAKKVNISIVPPLVLLPVFLHVASW
                     HFLLGVVVLTSLPMLALWYYYLTHRRKEQTLFFLSLGLFSLGYMYYVFLREVVPQGRV
                     GPTQLALLTCGLLLILLALYRAKKNPGYLSNDKSPSNSQIECPVKKGQEKTKGFPGTD
                     ASGSLNNRTLKDDVRGSSRVGLDSPAKVKEDWCAKCQLVRPARAWHCRICGICVRRMD
                     HHCVWINSCVGESNHQAFILALSIFLLTSVYGISLTLNTICRDRSLFTALFYCPGVYA
                     NYSSALSFTCVWYSVIITAGMAYIFLIQLINISYNVTEREVQQALRQKTGRRLLCGLI
                     VDTGQYNRGFLRNWLQFSTLGTHTVHTPAEDIV"
     exon            621..1319
                     /gene="Zdhhc23"
                     /gene_synonym="DHHC-23; Gm1751; Gm779; nidd"
                     /inference="alignment:Splign:2.1.0"
     exon            1320..1487
                     /gene="Zdhhc23"
                     /gene_synonym="DHHC-23; Gm1751; Gm779; nidd"
                     /inference="alignment:Splign:2.1.0"
     exon            1488..5864
                     /gene="Zdhhc23"
                     /gene_synonym="DHHC-23; Gm1751; Gm779; nidd"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggaagcgcgc gccgacctgc ggagcggcga ccgggggcga ctggctcgct cggcaggcgc
       61 gcgcaccggc ggtgctcaca ggtgggcgac tccgcccggc actcccgagc ctgccgtgcg
      121 gggtcgcagg ctcagccgcg cccaggggag tcggtcctcc tcccggtccc cgcctctgtc
      181 gggagggcag gtaacttccc cgccaaggtc attctccagg cccgcccacg ccctcggagc
      241 ggcgggttcg gagtgggctg gacgggcgac ctcggggctg ctggggctcc tggcatcccc
      301 gggccggtgg gtggttgcag cgccagggcg tcgctgcctg cacctgcgag ggcgttggcg
      361 ttaatgagaa gcaaggatgt gtttacagga tgtgagttga gttcttgcca cctttacctt
      421 ctgtgagctt cttatgcctc atggtgacag gtacaaatcc gtacactaaa gggcaatatg
      481 aagccagtca aaaaaaagaa aaccgaagaa cctgaattgg agcccctgtg ctgttgcgaa
      541 tacatagatc gaaatgggga aaagaaccac gtggctgcct gtttgtgtga ttgtcaagac
      601 ctcgatgaag gctgtgacag atggcttacc tgtcaatcac ttcggccgga gacttgcgaa
      661 agaatcacgg atacaatttc tgaccgcctc cgaattcctt ggctcagagg agccaaaaag
      721 gttaatatta gcatcgtccc tccacttgtg cttttgccgg ttttccttca cgtggcttcc
      781 tggcacttcc tgctgggggt ggtggttctg acctcccttc ccatgctggc actctggtat
      841 tactacctca ctcacagaag gaaagaacag acgctgtttt tcctgagcct cgggctgttc
      901 tcactgggct acatgtacta tgtgttcctg cgggaagtgg tcccccaagg gcgcgtgggg
      961 cccactcagc tggccctcct aacctgcggg ttacttctga tactcttagc cttgtaccga
     1021 gccaagaaga atccaggcta cctcagcaat gacaaatccc caagcaacag ccaaattgaa
     1081 tgcccggtca aaaaagggca ggagaagacc aaagggttcc ccggcacaga cgcctcgggg
     1141 agcctcaaca accgcacact gaaggacgat gttaggggtt cctccagggt ggggcttgac
     1201 agccctgcca aagtgaagga agactggtgt gccaagtgcc agctagtacg acccgcccgg
     1261 gcatggcatt gccggatatg cggtatctgt gtacggagaa tggaccatca ttgtgtctgg
     1321 ataaatagct gcgtcggaga atcaaaccat caagcattta tacttgccct ttccatcttc
     1381 ttgctcactt cggtttacgg aatatcgctg accttgaaca ccatttgtag ggatagaagc
     1441 ctcttcacag ccctcttcta ctgtcctgga gtttacgcta attacagctc agccctgtcc
     1501 ttcacctgtg tgtggtactc tgtgatcatc acagccggca tggcctacat cttcctcatc
     1561 cagctgataa acatcagcta caatgtaacg gagagggaag tgcagcaggc ccttcgccag
     1621 aagacagggc gccggctcct ctgcgggctc atcgtggaca caggccagta caacaggggc
     1681 ttcctgcgca actggctcca gttctccacc ctgggcacac acacagtcca cacccccgcc
     1741 gaagacatcg tctgaagtgc cttccgcgca gctctgcggg acattcctgt cctttccatt
     1801 tcacacgtca gtgtccatgc aggattcatt tccaccgccc acttctcaga gggactggag
     1861 ggctatactc aggtttggag agaggactgg agaaagggcc attttcttct gcctttataa
     1921 cttacgggag tttagtcctg aagccgcgag acagagccat tccttcctgt caccttgctg
     1981 actcaggcac cagatgctgc acagaggctg tggctcactc aaaccattca tgtaagtaag
     2041 gatgttagtt agaactcggg gcatttctcg ccctcctttc aattcttaat agccatatga
     2101 cccctcggta gagtcacttt tcccgagtct caggttcatc tgtatggggg cttctgctgc
     2161 ctggctacct catggagcag ccatgatggc cacctgagga gggatgtgga aacactccag
     2221 cccagtcaag cactcaaagg aatccggcat caggaaatcc cggggaccga agcagaccgc
     2281 ctgtcggtca gaacattgac accgatacta ttaagacggt cagtttgtac agtggcggaa
     2341 attctccgtg ttagactttg ttctcacagg ttagcaatga cgagaggtca agaggtcatc
     2401 ttgtcttgag aaggacagct gatgaagatt atgtgcgcag tgtggaatgg gaagaaattt
     2461 atttatttgt taatatatca tcttatagtt attataattc taacaagttt ttccctcctt
     2521 ccatgtttta cctggatgag gcgctagcac actggtagtg gtggctggaa ggtgaggaga
     2581 ctgtcctgag aacactgccc ctcttctgtg gctgtggagg ctggttacta tcaagggctt
     2641 gattttttat tattgttcat gtatttccag tgctgtaggt ttacggcact gaatgggaac
     2701 atcagcctac catgaactct ctccggggtg actgacacct tcccacgtcc acacggctac
     2761 tcactaatcc tccctaggaa cacgcatctc actaggagag aagagcatgg cacatgcact
     2821 ccccagtatg gaacagagca ttgctttcca gctcttcccc aggactaaga tgattccttt
     2881 gtgtctcaga actgaaactt ggagaagtct gcagattggg ccctcattct gccatagaaa
     2941 caggaggaaa actccatctt gaaagcattt gtcttttaca cttgtactgt ttcgggatcc
     3001 caaagataat ctgtgagacc ttaaatttgc cttggccttg ttgcttcata gaggagaaac
     3061 agtactttgt gggtttcttg ttggttgctg ttctgtgcct gcttgtacac actgaggaaa
     3121 tgccccgcct cttgagttag tctgccctta gcgccgcgtg ccaccctgag acttgccatt
     3181 aaccagggct ctcctgaaga caggtaccac attttcattc aggcttgtca ttgatctccc
     3241 cagatagcta ttgtttaata aacaatagac tccatattcc actgggtaag ccagagcgag
     3301 cttggggatg tttgctgact gcagtttcta cggcaatgcc tgtccctggt ctagattcag
     3361 acattcattt agaatgagag ttggcgtgga tacaactatt ttctgtcgtt gtgggtttta
     3421 ggtaagagag atggtagtaa tgtcaaagac agcgtatgtg ggcagaaatt ggtagttttc
     3481 atgtctcttg aatgccaggt acatagccaa ctttgaatgt ctaactgctg agaaaattta
     3541 cagaaatcgg atagtcagtc catgtgcctg ctgcctcttg agcttgccac tcaagggtca
     3601 catgaatgag gccactcagt ttccctcaaa tggacaggga ttccttgttg gctttgtggc
     3661 tcacaggaat taagaagctg ggacttttct ttttagattt tattttgcgt gtgtgtgtgt
     3721 gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt ataggggagg ccagaaaacc tcccctggag
     3781 ctggagttat aagcagccat gagtcagcta tcctgggcac tgagaactga acttggtcct
     3841 ctggaagagc agcacgtgct cctaactgct gagccatctc tctagcctcc aaagctgacg
     3901 tttctggaga actttgacgg tttgcagaac gaagctcaaa cctgtaaagg gctcagtccg
     3961 ctcattcgtt tgttttttac acatgtactg tttctgggat tccaaagatc agagataatt
     4021 tgtgagacct taaatttgcc ttggccttgt tgctccgtag aggggaaatg ggaactgtgc
     4081 acgcagcttt ttgcagttgg tttctaagag acagtctaca atcagacctt tgtgctttat
     4141 gatcttaaga tgtttgtggg attctggcat tctccagaca gtagattttt ttcacttgga
     4201 gtcttcaaaa aggcaagccc tttgtgagtg ggttgtccca agcatccgtg gataagctag
     4261 cagtcccttg accatgggag caagaactcc ccaccaaagt gactccagat aagcaggtcc
     4321 tcttgtccta catctaagct tcataaagat ccctccctgt tcccatcctt tatgttactg
     4381 ccatactgtc atgtatattc ccaggaaaga agacagagct tgcttctgaa aaactcaagg
     4441 gcaaacacta gggatgaaga ctggaaggaa ggaggaattc cttccttggt agaaaagtgt
     4501 tttaggagct tacaaagtac tgtgtaggtc accctcactg cctcgtcggc aagccactct
     4561 gacactgcta aaatgaagcc ttaaatgtgt tttggggaca atgctgtctg ctccctcaac
     4621 cacatagttg ctaggatatt gtaaatctct gctctcccag tggcattttc ctctgatgaa
     4681 tgcactgact gtttgttgtc cactgtaccg cctgcctgga aggcaactgc tgtaagcttg
     4741 ctctcttacg caatactcct tggtactcta atatttttag caaaagaaaa ctttgtattc
     4801 aagaacttcc cactgccaga aaacacaatt ccagtaagag tctatgtaat actgatatct
     4861 gcctgcctga cttccttctt ttgggtagga catcagcttt tattattaag ctcaattgac
     4921 agaagtgaaa acttgtagaa gcacagcttt aaccatgacg tctaataaaa gcaatgctcc
     4981 acgcactcac tcgttgcttt aaactagccg agtagatttc tgtgacggaa cttcccgtta
     5041 gccatatttt ggtaccctgc ctttcgaaaa ggacacttct caaacaagca gcgggttcga
     5101 gttgtgctgc ttgaagcctg gtttgctcag cgtaactttg caggtgaact gtttcatgtt
     5161 aaacacgcag aggccgtgtg gtgggaatga aagccatgct gactaaactg aacaccaaat
     5221 gaaactcagt gtgttcttgt gagtgtttgc tgagattcat ggaactgtcc agaagcagcg
     5281 gccagactga gtcctgttgc tgtgagctgg ctctgagcat tccactgtag gaacagcagg
     5341 ctgaatggtg agcagagcac atggctctcg ccacattggg cttgagactt ctaagtagtg
     5401 gagatgtcct ggtgtcgcgt ttcaccttta aaaaccccta cttaaaaggc aaagcttcaa
     5461 acccagagct agtctgctct aatggtacaa acgaaagcct ttcaggcaga gccactgaca
     5521 agatgccatg tcagagcagc caactcaagc ttgtgccaga gtctgggtga ttggatgacg
     5581 tgtgatgtct ttggggcctt ttcgtgatcc gatttctgtg tctgatggta gagtaagtga
     5641 atcctgggaa tgactttaat attaaattca gtatttgata tggatggcct acaacatgaa
     5701 gtaggattcc cgaagccaag ctgaggctga gggctgggct ctactctttt tgtccctttg
     5761 tctacatctt agcctttaaa actggaattt tacaaactcc tgccttttgt gcaaaataat
     5821 gtgaccacat tgtttaaaag gaaaataaag tgctttcttt tatg
//
