LOCUS       NM_029492               5288 bp    mRNA    linear   ROD 01-AUG-2024
DEFINITION  Mus musculus zinc finger, DHHC domain containing 20 (Zdhhc20),
            transcript variant 2, mRNA.
ACCESSION   NM_029492
VERSION     NM_029492.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5288)
  AUTHORS   Tomic,G., Sheridan,C., Refermat,A.Y., Baggelaar,M.P., Sipthorp,J.,
            Sudarshan,B., Ocasio,C.A., Suarez-Bonnet,A., Priestnall,S.L.,
            Herbert,E., Tate,E.W. and Downward,J.
  TITLE     Palmitoyl transferase ZDHHC20 promotes pancreatic cancer metastasis
  JOURNAL   Cell Rep 43 (5), 114224 (2024)
   PUBMED   38733589
REFERENCE   2  (bases 1 to 5288)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 5288)
  AUTHORS   Guo,G., Huss,M., Tong,G.Q., Wang,C., Li Sun,L., Clarke,N.D. and
            Robson,P.
  TITLE     Resolution of cell fate decisions revealed by single-cell gene
            expression analysis from zygote to blastocyst
  JOURNAL   Dev Cell 18 (4), 675-685 (2010)
   PUBMED   20412781
REFERENCE   4  (bases 1 to 5288)
  AUTHORS   Fukata,M., Fukata,Y., Adesnik,H., Nicoll,R.A. and Bredt,D.S.
  TITLE     Identification of PSD-95 palmitoylating enzymes
  JOURNAL   Neuron 44 (6), 987-996 (2004)
   PUBMED   15603741
REFERENCE   5  (bases 1 to 5288)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC119813.16, AK017158.1, AK163174.1, AK160951.1 and BC033914.1.
            
            On Jan 27, 2018 this sequence version replaced NM_029492.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK163174.1, AK151840.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-74                AC119813.16        145318-145391       c
            75-76               AK017158.1         2-3
            77-2892             AK163174.1         1-2816
            2893-3346           AK160951.1         135-588
            3347-5288           BC033914.1         1-1942
FEATURES             Location/Qualifiers
     source          1..5288
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 30.51 cM"
     gene            1..5288
                     /gene="Zdhhc20"
                     /gene_synonym="4930542A17Rik; 5033406L14Rik;
                     B230110O18Rik; HK11"
                     /note="zinc finger, DHHC domain containing 20"
                     /db_xref="GeneID:75965"
                     /db_xref="MGI:MGI:1923215"
     exon            1..274
                     /gene="Zdhhc20"
                     /gene_synonym="4930542A17Rik; 5033406L14Rik;
                     B230110O18Rik; HK11"
                     /inference="alignment:Splign:2.1.0"
     CDS             157..1263
                     /gene="Zdhhc20"
                     /gene_synonym="4930542A17Rik; 5033406L14Rik;
                     B230110O18Rik; HK11"
                     /EC_number="2.3.1.225"
                     /note="isoform 2 is encoded by transcript variant 2;
                     probable palmitoyltransferase ZDHHC20; DHHC-20; zinc
                     finger DHHC domain-containing protein 20; DHHC-containing
                     protein 20; acyltransferase ZDHHC20; DHHC
                     domain-containing cysteine-rich protein 20"
                     /codon_start=1
                     /product="palmitoyltransferase ZDHHC20 isoform 2"
                     /protein_id="NP_083768.4"
                     /db_xref="CCDS:CCDS27162.1"
                     /db_xref="GeneID:75965"
                     /db_xref="MGI:MGI:1923215"
                     /translation="MAPWTLWRCCQRVVGWVPVLFITFVVVWSYYAYVVELCVSTISR
                     TGEKGKTVVYLVAFHLFFVMFVWSYWMTIFTSPASPSKEFYLSNSEKERYEKEFSQER
                     QQDILRRAARDLPIYTTSASKAIRYCEKCQLIKPDRAHHCSACDRCVLKMDHHCPWVN
                     NCVGFTNYKFFMLFLLYSLLYCLFVAATVLEYFIKFWTNEPTVLNFPSAKFHVLFLFF
                     VSAMFFVSVLSLFSYHCWLVGKNRTTIESFRAPMFSYGIDGNGFSLGCSKNWRQVFGD
                     EKKYWLVPIFSSLGDGCSFPARLVGMDPEQASVANQSDYVRSIGSNQPFPIKPLSESK
                     NRLLDSESQWLENGAEEGVTKSGTNNHVTVEIEN"
     exon            275..301
                     /gene="Zdhhc20"
                     /gene_synonym="4930542A17Rik; 5033406L14Rik;
                     B230110O18Rik; HK11"
                     /inference="alignment:Splign:2.1.0"
     exon            302..405
                     /gene="Zdhhc20"
                     /gene_synonym="4930542A17Rik; 5033406L14Rik;
                     B230110O18Rik; HK11"
                     /inference="alignment:Splign:2.1.0"
     exon            406..526
                     /gene="Zdhhc20"
                     /gene_synonym="4930542A17Rik; 5033406L14Rik;
                     B230110O18Rik; HK11"
                     /inference="alignment:Splign:2.1.0"
     exon            527..596
                     /gene="Zdhhc20"
                     /gene_synonym="4930542A17Rik; 5033406L14Rik;
                     B230110O18Rik; HK11"
                     /inference="alignment:Splign:2.1.0"
     exon            597..629
                     /gene="Zdhhc20"
                     /gene_synonym="4930542A17Rik; 5033406L14Rik;
                     B230110O18Rik; HK11"
                     /inference="alignment:Splign:2.1.0"
     exon            630..750
                     /gene="Zdhhc20"
                     /gene_synonym="4930542A17Rik; 5033406L14Rik;
                     B230110O18Rik; HK11"
                     /inference="alignment:Splign:2.1.0"
     exon            751..892
                     /gene="Zdhhc20"
                     /gene_synonym="4930542A17Rik; 5033406L14Rik;
                     B230110O18Rik; HK11"
                     /inference="alignment:Splign:2.1.0"
     exon            893..1019
                     /gene="Zdhhc20"
                     /gene_synonym="4930542A17Rik; 5033406L14Rik;
                     B230110O18Rik; HK11"
                     /inference="alignment:Splign:2.1.0"
     exon            1020..1109
                     /gene="Zdhhc20"
                     /gene_synonym="4930542A17Rik; 5033406L14Rik;
                     B230110O18Rik; HK11"
                     /inference="alignment:Splign:2.1.0"
     exon            1110..1225
                     /gene="Zdhhc20"
                     /gene_synonym="4930542A17Rik; 5033406L14Rik;
                     B230110O18Rik; HK11"
                     /inference="alignment:Splign:2.1.0"
     exon            1226..1302
                     /gene="Zdhhc20"
                     /gene_synonym="4930542A17Rik; 5033406L14Rik;
                     B230110O18Rik; HK11"
                     /inference="alignment:Splign:2.1.0"
     exon            1303..5247
                     /gene="Zdhhc20"
                     /gene_synonym="4930542A17Rik; 5033406L14Rik;
                     B230110O18Rik; HK11"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5157..5162
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zdhhc20"
                     /gene_synonym="4930542A17Rik; 5033406L14Rik;
                     B230110O18Rik; HK11"
                     /note="hexamer: AATAAA"
     regulatory      5165..5170
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zdhhc20"
                     /gene_synonym="4930542A17Rik; 5033406L14Rik;
                     B230110O18Rik; HK11"
                     /note="hexamer: GATAAA"
     polyA_site      5174
                     /gene="Zdhhc20"
                     /gene_synonym="4930542A17Rik; 5033406L14Rik;
                     B230110O18Rik; HK11"
                     /note="major polyA site"
     polyA_site      5190
                     /gene="Zdhhc20"
                     /gene_synonym="4930542A17Rik; 5033406L14Rik;
                     B230110O18Rik; HK11"
ORIGIN      
        1 gggccaggcg cagggagggg cggagttgtg gcgtcgccct tcgccactgc ttgcggcggc
       61 ggagcctcgg gggcggggaa gctggcgaca gggccgctgg ggtcttgtgg tcctacagaa
      121 tcgtgggcag cgggacccgg cagtcagcag aggaacatgg cgccctggac actctggcgc
      181 tgctgccaac gcgtggtggg ctgggttccg gtgctcttca tcacctttgt ggtcgtctgg
      241 tcctactacg cgtacgtggt ggagctgtgc gtgagtacta tttccagaac aggagagaaa
      301 ggaaagaccg ttgtttacct tgtggctttc catctgttct ttgttatgtt tgtatggtct
      361 tattggatga caatattcac gtctcctgct agcccttcca aagagttcta cttgtcaaac
      421 tctgagaagg agcgttatga gaaggagttc agccaagaaa gacagcaaga cattttgaga
      481 agagcggcaa gagacctgcc tatctacacc acatcagctt caaaggctat ccgatattgt
      541 gaaaaatgtc agttgattaa acctgaccga gcccatcact gctcagcatg tgacagatgt
      601 gttcttaaga tggatcatca ctgtccatgg gtgaataact gtgtgggatt tactaattac
      661 aaattcttca tgctgttttt gttgtattct ctactatatt gcctttttgt ggctgcaaca
      721 gttttagagt attttataaa attttggacg aatgaaccaa cagttttaaa tttccccagc
      781 gcaaagttcc acgtactgtt cctttttttt gtgtctgcaa tgttcttcgt cagtgtgctc
      841 tcactattta gctaccattg ctggctggtt ggaaaaaata gaacgacaat agaatcattt
      901 cgtgcaccta tgttttctta tggaatagat ggaaatggtt tctctcttgg atgcagtaaa
      961 aattggagac aagtctttgg tgatgaaaag aaatattggc tagttccaat attctcaagt
     1021 ttgggtgatg gttgcagttt tccagctcgc cttgtgggga tggatccaga acaagcttct
     1081 gttgcaaacc agagtgacta cgtcagaagt attggctcaa atcaaccttt tcctatcaaa
     1141 ccacttagtg aatcaaaaaa ccgcttattg gacagtgaat ctcagtggct agagaatgga
     1201 gctgaagaag gagtcaccaa atcagggaca aataaccatg ttacagtgga aatagaaaat
     1261 tgagtactac ttgttcataa ctaaccattt gatgagtgca aggtatataa aaacacattt
     1321 tggactattt tcaattttat ttgcaagaaa atgatggatg gaatgaaata cttgaagtgt
     1381 aacagaagat atatttttaa aaggaaatgt ttgtacagtt tgatggatcc acagaagcac
     1441 tgcagagcgg aaagatgcct taatttttag tgtccatttg tgtgacattg cctcacagct
     1501 caaaagtgac ttaattttcc tttggaaata acacctgttt tacaatgcta tcgtcacgtg
     1561 ttaacatgcc atatgtattt taaacatctg agttacaaca ttagagctat ttcttagtat
     1621 ccacataaat tttcacccca aaaacacaaa ctaaaaagtt gtctgtggtg aagtatacct
     1681 agggaaaacg ggggctaaaa atgatgccca aatcactgat tcttgtgctg tataagggaa
     1741 agaaataccg ctttttttat tagatgttta ctaatttata attactgttt tatacttttc
     1801 aacattttaa taaagatttt ttaattattg gctataaaat aacactcaaa gaaggattca
     1861 ggtacctaaa tataatcatt tagaacattg aagatattaa tataattcag tgaaggttta
     1921 gttagaagca ttaatacttc taattagtac ttttaaaagc caagtggcac atgcctataa
     1981 tcccagcatt cagaaggctg aggtaatatt ctgtgatttt gagtctagca ttggttgcat
     2041 agagaccgta tctaaaacac agaataatac agccatgtgg tgtagtgtga gcccaaggct
     2101 caaaggaaac atggtaggaa acaactacac gttggtattc tctgctcttt aattactagt
     2161 tgttgagtgt tcaagggaag tttttatggg cagggaagca cagaggttca cgtgctatcc
     2221 aaagacctaa cacatatatg aataggtggg agtgactaga aaaaaagaga atgaaagaag
     2281 gagtattata aacaagtaaa caaattttca tccctaaaag tatatagact acaacatgct
     2341 attaaatagg atttcattta ggcaatgtct aaaaattact gtggtcgttt acaggaatcc
     2401 tgtagccgag tcaacagcaa ctcaaatgca gttcagataa ggatgaaata tgtaaaacaa
     2461 aaccacgacg tcccaggctt gggctggaga aatgtctcag tagataaagg cccttgccct
     2521 cagacctaca acctgacatc agccacattc tggaagaaga tacctaactc ccacacattg
     2581 tcctctggca tttacatgtg cactatggtg cacatagact ctttaaaaga tagtacgttt
     2641 ttagcgtcta gtggctttaa tagaaatggc tgtattgagg agattagtcc actggtctgt
     2701 caaaaggcaa tgtagagatg ctatttttgg tttataccgt ttatcaaaga aacaaacgcc
     2761 aggcgtggtg gcgcacgcct ttaatcccag cacttgggag gcagaggcag gtggatttct
     2821 gagttcgagg ccggcctggt ctacagagtg agttccagga cagccagggc tacacagaga
     2881 aacccagtct tgaaaaacca aaaaaaaaag aaagaaaaaa agaaagaaag aaagaaagaa
     2941 agaaagaaag aaagaaagaa agaaatgaaa caatcccaaa tgattgcttg aggtggacca
     3001 gcagagagac gtctctgatg tgctgctgtc taggatgtgg ctatgcagtg tctgtgtgca
     3061 caataggact gtggagaagg catcctgcag gagttggact ataggactcc caacattacc
     3121 cagtgctgaa gtttgcagat aaccttgctt tttatttacc caccaagtag ctgtcaagtc
     3181 ctctgaatat caaatattat actaaagata gcgctgtgat ttccaaatcc tgcataaatc
     3241 aagatcgctg ctgttctaac tttgcgattt gggaagttta ctgaattccc attgactgca
     3301 ctaattatga atcttaagta actttccctt tggaccaaag gagtgagtca gctttggcac
     3361 catggtttaa agttgtatgt agtatgaatt cctcttcatt tcagctcttt tgactttcat
     3421 tctataaaaa cagtgactta agagatagca gttactgcta ggcatgctgg cgcctgctgg
     3481 ccgtctcagc acttgggagt gtgaatcagg ttggtctagc tcactctcag caccaccagc
     3541 agcctgtgct gcatgaagcc tgtgctaaac agcccgagag gaaacgaaga tcaattacta
     3601 accagaaata caacttcaat ttggtagtgt gcatgctact ttcagaaata ttctagtatt
     3661 tcagtgtttc tatatttata ccaagggatt tgcatgcacc tggcatagtt tgccccttta
     3721 acatactatt acgtagaagt atcaaatttc tgagttctta tcatttgttt attagcagag
     3781 taaaaccatt tctagttttc cactttggta gcctttatag ccagcttttt gccacattct
     3841 aaaatattta gctgcctttt gttgtttcgg ttttgtttca ttttagtgct gggaatcaaa
     3901 tccagggcct tctgcatact aggcaagtcc cctaccactg agctacatcc ctggcccgag
     3961 ctgaagctgt tcatacgtgt cagtggccgc tcattaggga ccagcaaggg accagcatgg
     4021 gaatcaggga aggctggctg tttagtatgt gaactggcat tgcgtctgct atcagggggg
     4081 gactacattg aaacagagct ttgccaaaat ttcaaacact tgaacatttg tgaagaaaat
     4141 ggagttgaat ttcaggtctt gcccttgcca ttaaaaacat cagacaggag acttggttta
     4201 ctgggtacag aggtacttga ctgttgagta cctgcggcac ctgaccctgt cactgtgcca
     4261 accaaagcag ctgcagtgta ccagctattg acatgaacat gtttacaaag ttgagttttg
     4321 tcttcataaa agaatgattt ttaaaaaact ttttacatag ttatgactca atgtgtttaa
     4381 agcataacaa gttagcttaa atatatggtc tttacttgaa ttttaattct tacagatagc
     4441 aaattttgac tgtttacagg aatgcttgaa atgagtcaag agatctctaa ttctctctga
     4501 agcaaaactg atacaggctt agtgttcgag cctgtgtatt tgtggcattg gataggcagt
     4561 aactcaaaac tacgtttcgc ttacatcttg ttctataaag tagtactttt gcgtggataa
     4621 gtatttttaa ctgatattaa gaaatcatat ttttgcattt cagtcaaact agtaagaaca
     4681 tacgtaaaag tacaaatgag atgtaaatct gaaattcatg tttcatatga tcaagctgta
     4741 tttttaaatt caaatttaaa atacaataga gattcagaaa ggtccatatt tttctaatga
     4801 cttcatgcta tattattttc ttgagttacg taaagcaagg aattgtattt gtattaagga
     4861 gctaaggaag ctgttagttt attatatttg tacatgatta cagacaagcc tatgcccatt
     4921 taaaagaaaa gatggatact atttaaggtg atatttaata tgtttttcta taaacaagtt
     4981 tgaaatatag tttgccttag ttgtcttatc agtagcatag ccttctattt atttctcatt
     5041 atgtgaacct ggactatgac cagtgactct tgtctctgta ttttggatgg cctaacctac
     5101 attactatgt gtgcatttta caactttttt ttttcagaaa ccataattac tttattaata
     5161 aacagataaa gatattgtct tgttttttaa tggttttgtt gccattatat ttgtcaaatg
     5221 agaaaataat tgtcattttg atccgcaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     5281 aaaaaaaa
//
