LOCUS       NM_146073               3115 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus zinc finger, DHHC domain containing 14 (Zdhhc14),
            mRNA.
ACCESSION   NM_146073
VERSION     NM_146073.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3115)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3115)
  AUTHORS   Sanders,S.S., Hernandez,L.M., Soh,H., Karnam,S., Walikonis,R.S.,
            Tzingounis,A.V. and Thomas,G.M.
  TITLE     The palmitoyl acyltransferase ZDHHC14 controls Kv1-family potassium
            channel clustering at the axon initial segment
  JOURNAL   Elife 9, e56058 (2020)
   PUBMED   33185190
  REMARK    GeneRIF: The palmitoyl acyltransferase ZDHHC14 controls Kv1-family
            potassium channel clustering at the axon initial segment.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3115)
  AUTHORS   Jung,H., Park,H., Choi,Y., Kang,H., Lee,E., Kweon,H., Roh,J.D.,
            Ellegood,J., Choi,W., Kang,J., Rhim,I., Choi,S.Y., Bae,M.,
            Kim,S.G., Lee,J., Chung,C., Yoo,T., Park,H., Kim,Y., Ha,S.,
            Um,S.M., Mo,S., Kwon,Y., Mah,W., Bae,Y.C., Kim,H., Lerch,J.P.,
            Paik,S.B. and Kim,E.
  TITLE     Sexually dimorphic behavior, neuronal activity, and gene expression
            in Chd8-mutant mice
  JOURNAL   Nat Neurosci 21 (9), 1218-1228 (2018)
   PUBMED   30104731
REFERENCE   4  (bases 1 to 3115)
  AUTHORS   Inagawa,M., Nakajima,K., Makino,T., Ogawa,S., Kojima,M., Ito,S.,
            Ikenishi,A., Hayashi,T., Schwartz,R.J., Nakamura,K., Obayashi,T.,
            Tachibana,M., Shinkai,Y., Maeda,K., Miyagawa-Tomita,S. and
            Takeuchi,T.
  TITLE     Histone H3 lysine 9 methyltransferases, G9a and GLP are essential
            for cardiac morphogenesis
  JOURNAL   Mech Dev 130 (11-12), 519-531 (2013)
   PUBMED   23892084
REFERENCE   5  (bases 1 to 3115)
  AUTHORS   Guo,G., Huss,M., Tong,G.Q., Wang,C., Li Sun,L., Clarke,N.D. and
            Robson,P.
  TITLE     Resolution of cell fate decisions revealed by single-cell gene
            expression analysis from zygote to blastocyst
  JOURNAL   Dev Cell 18 (4), 675-685 (2010)
   PUBMED   20412781
REFERENCE   6  (bases 1 to 3115)
  AUTHORS   Corbo,J.C. and Cepko,C.L.
  TITLE     A hybrid photoreceptor expressing both rod and cone genes in a
            mouse model of enhanced S-cone syndrome
  JOURNAL   PLoS Genet 1 (2), e11 (2005)
   PUBMED   16110338
  REMARK    Erratum:[PLoS Genet. 2008 Jan;4(1):e18]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK036699.1, AK041648.1, AK041496.1, AK046719.1 and AK080845.1.
            
            On Sep 1, 2004 this sequence version replaced NM_146073.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK046719.1, BC059814.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-130               AK036699.1         2-131
            131-912             AK041648.1         123-904
            913-1092            AK036699.1         915-1094
            1093-1690           AK041648.1         1089-1686
            1691-1915           AK041496.1         1374-1598
            1916-2468           AK046719.1         1904-2456
            2469-3033           AK080845.1         2473-3037
            3034-3115           AK046719.1         3022-3103
FEATURES             Location/Qualifiers
     source          1..3115
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 3.23 cM"
     gene            1..3115
                     /gene="Zdhhc14"
                     /gene_synonym="B530001K09Rik; New1cp"
                     /note="zinc finger, DHHC domain containing 14"
                     /db_xref="GeneID:224454"
                     /db_xref="MGI:MGI:2653229"
     exon            1..1092
                     /gene="Zdhhc14"
                     /gene_synonym="B530001K09Rik; New1cp"
                     /inference="alignment:Splign:2.1.0"
     CDS             848..2317
                     /gene="Zdhhc14"
                     /gene_synonym="B530001K09Rik; New1cp"
                     /EC_number="2.3.1.225"
                     /note="NEW1 domain containing protein; probable
                     palmitoyltransferase ZDHHC14; DHHC-14; zinc finger DHHC
                     domain-containing protein 14; DHHC domain-containing
                     cysteine-rich protein 14"
                     /codon_start=1
                     /product="palmitoyltransferase ZDHHC14"
                     /protein_id="NP_666185.3"
                     /db_xref="CCDS:CCDS37422.1"
                     /db_xref="GeneID:224454"
                     /db_xref="MGI:MGI:2653229"
                     /translation="MPPGGGGPMKDCEYSQISTHSSSPMESPHKKKKIAARRKWEVFP
                     GRNKFFCNGRIMMARQTGVFYLTLILILVTSGLFFAFDCRYLAEKITPAIPVVGGILF
                     FFVMGTLLRTSFSDPGVLPRATPDEAADLERQIDIANGTSSGGYRPPPRTKEVVINGQ
                     TVKLKYCFTCKIFRPPRASHCSLCDNCVEQFDHHCPWVGNCVGKRNYRFFYMFILSLS
                     FLTVFIFAFVITHVIHRSQQKGFLDALKDSPASVLEAVICFFSVWSIIGLSGFHTYLI
                     SSNQTTNEDIKGSWSNKRGKENYNPYSYGNIFTNCCVALCGPISPSLIDRRGYVQPDT
                     PQPAAPSNGITMYGATQSQSDMCDQDQCIQSTKFVLQAAATPLLQSEPSLTSEELHMP
                     GKPGLGTPCASLTLGQPTPPSSMPNLATEATLSDIMPLKDEHGGHQFLTPDEAPSPPR
                     MLGAGSPLAHSRTMHMLGLASQDSLHEDSVRGLVKLSSV"
     exon            1093..1253
                     /gene="Zdhhc14"
                     /gene_synonym="B530001K09Rik; New1cp"
                     /inference="alignment:Splign:2.1.0"
     exon            1254..1412
                     /gene="Zdhhc14"
                     /gene_synonym="B530001K09Rik; New1cp"
                     /inference="alignment:Splign:2.1.0"
     exon            1413..1550
                     /gene="Zdhhc14"
                     /gene_synonym="B530001K09Rik; New1cp"
                     /inference="alignment:Splign:2.1.0"
     exon            1551..1599
                     /gene="Zdhhc14"
                     /gene_synonym="B530001K09Rik; New1cp"
                     /inference="alignment:Splign:2.1.0"
     exon            1600..1702
                     /gene="Zdhhc14"
                     /gene_synonym="B530001K09Rik; New1cp"
                     /inference="alignment:Splign:2.1.0"
     exon            1703..1812
                     /gene="Zdhhc14"
                     /gene_synonym="B530001K09Rik; New1cp"
                     /inference="alignment:Splign:2.1.0"
     exon            1813..1915
                     /gene="Zdhhc14"
                     /gene_synonym="B530001K09Rik; New1cp"
                     /inference="alignment:Splign:2.1.0"
     exon            1916..3115
                     /gene="Zdhhc14"
                     /gene_synonym="B530001K09Rik; New1cp"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3000..3005
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zdhhc14"
                     /gene_synonym="B530001K09Rik; New1cp"
                     /note="hexamer: AATAAA"
     polyA_site      3035
                     /gene="Zdhhc14"
                     /gene_synonym="B530001K09Rik; New1cp"
                     /note="major polyA site"
ORIGIN      
        1 gcgcgccggg gctgagcctt gcaaacaagt gtctctggca gtgtccccgc ggccctccgg
       61 cggccctcgt cgcgctaggg ttgtcttctc cggacagaag gaaccgagga agccccggga
      121 gccgccaccg ctaccgccgc caccaccctc ggccttagcc ccgcgttagg ggccgcggac
      181 tcagctcggc tgctcggctc gtggatgcgg ggtcgcagcg cgggcagcgc cccggctcct
      241 acagagcagc tcctgacaga agaacgcgcg tggctgtccc cacccctggg aggggttgcc
      301 ggtgtcgcga gctgccgctc agtttgcagc tctctctcct gggagaatcc gtcaccggga
      361 aagagtagaa accacctggt cgaggcgcag aagtggctcc ggagggagcc ggcgtaaggt
      421 ctgctgcctc gtgtccgcta agggcgcggc gatccgggat ccgccggccg gagcccaagc
      481 gcagccggga gcttgcgggt ggcgaagcca ggcgcaccgc cttctgggtg tctgctgagc
      541 ggttccccgc gtcccgcggg gtcctgcagc cccgaccccc cggctggaag ccacggagaa
      601 ccgctgccga ggactgcgga ccaacatcgt ccctcccgaa agcggattct gctatgacag
      661 ctgggctctc caaggggtta acctgggtgt cctccgtaaa gttgtcgccg agccgggagc
      721 ccgtttaggg gtcgcagcgc cgcggctcgg ggggcggccg agtggccggc ggcggccgtg
      781 gctcggcgga acccgcgcgg ccggggggct tctgggggtg tgcgccccca gccggctgcc
      841 ctcgtggatg cctcccggcg gcggcgggcc catgaaagac tgcgagtaca gtcagatcag
      901 cacccacagc tcctctccca tggagtcgcc ccacaagaag aagaaaatcg cggcccggag
      961 gaaatgggag gtgttcccag gaagaaacaa gttcttttgc aacgggagga tcatgatggc
     1021 ccggcagacc ggcgtcttct acctgactct cattctcatc ctggtcacta gtggactctt
     1081 cttcgccttc gactgtcggt acctggcaga gaagatcacc cctgccatcc ccgtggtcgg
     1141 tggcatcctg ttcttctttg tgatggggac actgcttcgg accagcttca gtgacccggg
     1201 agtcctccct cgagccactc ctgatgaagc cgctgatctg gaaaggcaaa tagatatagc
     1261 caacggcacc agttcagggg ggtatcgccc gcctcccaga accaaagaag tcgtcatcaa
     1321 tggccagacc gtgaaactaa agtactgttt tacctgcaag attttccgcc cccctcgagc
     1381 ctcccactgc agcctgtgtg ataactgcgt agaacagttt gatcaccact gtccctgggt
     1441 aggcaactgt gtggggaaaa gaaactacag atttttttat atgtttattt tatccctgtc
     1501 ctttctgaca gtctttatat ttgcattcgt tatcacacac gtcatccatc gttcacagca
     1561 aaagggattc ctcgatgccc ttaaggacag tccagcgagt gtgctagagg ctgtaatatg
     1621 cttcttctct gtctggtcca tcattggcct ttcaggtttc cacacgtacc tgatcagctc
     1681 caaccagacc acaaacgaag acatcaaagg ctcttggtcc aataaaagag gtaaagaaaa
     1741 ttacaatccc tacagctatg gaaacatctt cacaaattgc tgtgtcgccc tatgtgggcc
     1801 catctctccc agcctaattg acagaagagg ctatgtccag cccgacacac cacagccagc
     1861 agcaccatca aatgggatca ctatgtatgg ggccacacag tcgcagagtg acatgtgcga
     1921 ccaagaccag tgcattcaga gcaccaaatt cgttttgcag gccgcagcca cgcccctgct
     1981 tcagagcgag cccagcctca ccagcgaaga gctgcatatg cctgggaaac ccggcctggg
     2041 caccccatgt gctagcctga cgctgggcca gcccacacca ccctcctcca tgcccaacct
     2101 tgccacggag gccacactct cagacattat gcccctgaag gatgagcatg ggggccatca
     2161 gtttctgacc ccagatgagg caccctcacc gccaaggatg ctgggggcag gcagccctct
     2221 agcacatagc cgtaccatgc acatgttggg tctggccagc caggactccc tgcacgaaga
     2281 ctccgtgagg ggcttggtaa agctcagctc cgtgtgacct gcatggccag ccctggggac
     2341 cacaggtgac aaacaaaaac aaattactgg acatagccaa gaggacgttt tgtttggaat
     2401 ctgcagagtg gaccgggaag aggagactcc ctcaatggga ggagcctgga attgaaagag
     2461 gcagcgtgga tgcagcgtgc agcgccctct gtcggctgct tttgggacag acacgaggaa
     2521 aattttcgac actggtggcc agactgaaat tggacctaat gttacagcta ctaattgaaa
     2581 tccacccgcc gttccatttg ttcattaaaa caaaacgaaa caaaagttcc aaagggaaaa
     2641 gccggccaga catgggattg catgccacac tatagtctgt gttacagcag tggtattcca
     2701 gaagaaaaga tgtctctctg ttttccttct ttttaatctt gtgatacttt ccaatgtgac
     2761 agaccgaacc cggtgggtaa tgccatcctt cgcgacttac tggacttagc tgtatgagga
     2821 tgggcgtttc ctgatgaaga gggttactgg gggcatcccc tgttgcagac ggcacctggg
     2881 gtctatcctg ccctggacag acattttaac cctctgtcaa tgctcagatg gatgtcatat
     2941 tgtgccacca tggggcagtc ctcgcctcct gtgtgacaat gaccttccta tggacagcca
     3001 ataaaatgac tcctctgtta ttttcttgat ctgtatacag ttgtcaacag cttgcatgta
     3061 gttacttact tgttcacatt atctctggta aggaataatt caaaacagcc aaagt
//
