LOCUS       NM_025893               4361 bp    mRNA    linear   ROD 06-JUN-2024
DEFINITION  Mus musculus zinc finger, CCHC domain containing 18 (Zcchc18),
            transcript variant 3, mRNA.
ACCESSION   NM_025893
VERSION     NM_025893.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4361)
  AUTHORS   Bohuslavova,R., Fabriciova,V., Lebron-Mora,L., Malfatti,J.,
            Smolik,O., Valihrach,L., Benesova,S., Zucha,D., Berkova,Z.,
            Saudek,F., Evans,S.M. and Pavlinkova,G.
  TITLE     ISL1 controls pancreatic alpha cell fate and beta cell maturation
  JOURNAL   Cell Biosci 13 (1), 53 (2023)
   PUBMED   36899442
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4361)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4361)
  AUTHORS   Wang,H., Liu,X.L., Shu,S.N., Huang,Y.J. and Fang,F.
  TITLE     Identification of proteins that interact with murine
            cytomegalovirus early protein M112-113 in brain
  JOURNAL   Chin Med J (Engl) 124 (21), 3532-3536 (2011)
   PUBMED   22340173
REFERENCE   4  (bases 1 to 4361)
  AUTHORS   McKee,A.E., Minet,E., Stern,C., Riahi,S., Stiles,C.D. and
            Silver,P.A.
  TITLE     A genome-wide in situ hybridization map of RNA-binding proteins
            reveals anatomically restricted expression in the developing mouse
            brain
  JOURNAL   BMC Dev Biol 5, 14 (2005)
   PUBMED   16033648
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL672008.8, BY261402.1, AK005317.1, AK075607.1, AV174394.2,
            AL954296.9 and AK134856.1.
            
            On Dec 1, 2017 this sequence version replaced NM_025893.2.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK005317.1, SRR1660825.124867.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849377
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-8                 AL672008.8         157803-157810
            9-31                BY261402.1         1-23
            32-1290             AK005317.1         2-1260
            1291-2268           AK075607.1         887-1864
            2269-2812           AV174394.2         59-602
            2813-3048           AL954296.9         3009-3244
            3049-4361           AK134856.1         3422-4734
FEATURES             Location/Qualifiers
     source          1..4361
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 59.1 cM"
     gene            1..4361
                     /gene="Zcchc18"
                     /gene_synonym="1500031H04Rik; Sizn2"
                     /note="zinc finger, CCHC domain containing 18"
                     /db_xref="GeneID:66995"
                     /db_xref="MGI:MGI:1914245"
     exon            1..206
                     /gene="Zcchc18"
                     /gene_synonym="1500031H04Rik; Sizn2"
                     /inference="alignment:Splign:2.1.0"
     exon            207..261
                     /gene="Zcchc18"
                     /gene_synonym="1500031H04Rik; Sizn2"
                     /inference="alignment:Splign:2.1.0"
     exon            262..401
                     /gene="Zcchc18"
                     /gene_synonym="1500031H04Rik; Sizn2"
                     /inference="alignment:Splign:2.1.0"
     exon            402..4361
                     /gene="Zcchc18"
                     /gene_synonym="1500031H04Rik; Sizn2"
                     /inference="alignment:Splign:2.1.0"
     CDS             527..1708
                     /gene="Zcchc18"
                     /gene_synonym="1500031H04Rik; Sizn2"
                     /note="SMAD-interacting zinc finger protein 2"
                     /codon_start=1
                     /product="zinc finger CCHC domain-containing protein 18"
                     /protein_id="NP_080169.2"
                     /db_xref="CCDS:CCDS30427.1"
                     /db_xref="GeneID:66995"
                     /db_xref="MGI:MGI:1914245"
                     /translation="MASLLARMGNSRRQNAAFMPFAHSMLRALGRSLGPLIANIAERN
                     IQSFSGRAELGPGEETFENWLSQVHEVLPDWPMSEEEKIKRLMRTLRGPAREAMRLFQ
                     ADNPNLNVAEFLRAMKLLFGASESSITAHGKFLSTLQAQGEKPSLYVIRLEVQLQNAI
                     QAGVLPQSEANRTRLHQLLVGAELSRELRTKLKGLLQMHAHNEQENLPDFLELIRMIR
                     EEEDWDETFLRNKRPRRSETVMERAASPVVFQGSLPIVIGSADCNVIEIDDSQDDSDE
                     DVILVEPEDPPLSSPGASSLRGTASTQEEMLIIESPDDFDEESPSTSSGSGQRNNGPG
                     DLGRTRKRKYPIRCPHCGEEGHAKETCDNTSNKGQVFENLIVTLQELTHMERPKPSVP
                     Y"
     regulatory      2240..2245
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zcchc18"
                     /gene_synonym="1500031H04Rik; Sizn2"
                     /note="hexamer: AATAAA"
     polyA_site      2253
                     /gene="Zcchc18"
                     /gene_synonym="1500031H04Rik; Sizn2"
                     /note="major polyA site"
     polyA_site      2269
                     /gene="Zcchc18"
                     /gene_synonym="1500031H04Rik; Sizn2"
     regulatory      2791..2796
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zcchc18"
                     /gene_synonym="1500031H04Rik; Sizn2"
                     /note="hexamer: CATAAA"
     polyA_site      2817
                     /gene="Zcchc18"
                     /gene_synonym="1500031H04Rik; Sizn2"
     regulatory      4313..4318
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zcchc18"
                     /gene_synonym="1500031H04Rik; Sizn2"
                     /note="hexamer: AATAAA"
     polyA_site      4347
                     /gene="Zcchc18"
                     /gene_synonym="1500031H04Rik; Sizn2"
ORIGIN      
        1 ttcgtcactc tcttttgtct caatgggcag agactaaaag ccgccgctgc tgctctgcag
       61 gctgaaattg agggcggggg cagctatagc tgccttggaa accgcggctg cgactctgct
      121 acccctggct gggcgaccct gcagagagcc taacccagac agctctgagg ctgaggcgcc
      181 atcctttcct ctgcaaggcc tacgagcagc tcatcaaagc cgatttcaaa cgtgaattct
      241 gtgtgactga ttgcagagct gtttagacta gaggcccagg gcacctggat cggagagcct
      301 gcggtcagag atcaatccta cccggacaag agctattgcg gaaagcacct gttgcagaga
      361 gtaggcttga aataaaggtg gaagccagtt tctgagctct gtttctaccc aaacacaagg
      421 aagagactgc tggggaacgt tcctttggag gtttctgcag attggactgc ttttgtttgc
      481 agaaagtcca ggcgtcttgt attcagatat ccaattgttg tcaggcatgg ctagcctcct
      541 tgctaggatg ggtaacagtc gccggcagaa tgcagctttt atgccttttg cccattccat
      601 gctgagggcc ctggggagga gccttggtcc tttgattgcc aacattgcag agagaaacat
      661 acagtcgttc tctgggaggg cagagctagg acccggggaa gaaacctttg aaaactggct
      721 aagccaagtc catgaggtcc tgccagattg gcctatgtct gaagaagaaa agatcaagcg
      781 cctgatgaga acccttaggg gccctgcccg ggaggccatg cgtttgttcc aggctgacaa
      841 tcccaatcta aatgtcgcag aatttttgcg ggcaatgaag ctgctctttg gagcgtctga
      901 gagcagtata acagcgcatg gcaaattttt aagcaccctg caggcacagg gagagaaacc
      961 atccctgtat gtgatccgtt tagaggtgca gctacagaat gctatccagg caggggtcct
     1021 tcctcagagc gaggcaaaca ggactcgcct gcaccagctc cttgtagggg ctgagctgag
     1081 tagggagctg cgcaccaagc ttaaggggct tctccaaatg catgcgcata atgagcagga
     1141 aaaccttcct gacttcctgg agttgatcag gatgataagg gaggaagagg attgggatga
     1201 gacattcctt agaaataagc ggcccagaag atctgagaca gtgatggagc gggcagccag
     1261 ccctgtggtc tttcaaggct ccctgcctat agtgataggc agtgccgact gtaatgtgat
     1321 agagatagat gattcccagg atgattcaga tgaagatgtg atcctggtgg agcccgagga
     1381 ccctccactc tcatccccag gtgcctcatc cctccgaggc acagccagta ctcaggaaga
     1441 gatgctgatt attgagtccc ctgatgattt tgatgaggag tctccttcca ctagcagtgg
     1501 ttctgggcaa aggaataacg ggcctgggga tctaggtaga accagaaagc gcaagtaccc
     1561 aatccgctgt cctcattgtg gtgaagaggg ccacgccaaa gaaacctgtg acaataccag
     1621 caacaagggc caggtttttg agaatttgat agtcactctg caggagctga ctcacatgga
     1681 gagacccaaa ccctctgtac catactaagg tgtgaccctc ggccccagat cagtgtttga
     1741 atctcctcag aagctaattc tggaggaaaa agggatgggg tgggctgctg acattaagga
     1801 attcatttaa aacaagcttt ttctttggag aagaaaaagc aaactggggt accatgcaac
     1861 agagaggcat gggcccacat cattccttgc tcattccatt aactgcttaa tggttgtttc
     1921 tctgtgtgtc tttctctggt gattttaatc tatccgtgaa gtggtacctt tttgaacctt
     1981 ccaaatgaaa ttaaaaagaa aaaaactaaa gtgtgcatta cctgaaaaat ctcaccctga
     2041 attgtcagcc ccttggtgaa tgtcctgcgt atttccctgt acctgtgtgc ctcggtatat
     2101 atgtattgat aaaagtgatc acatataagt gctgttctat agtatgtatt ttttcatcag
     2161 gcagtatata ttgtggactt ctaaatagat gaatatataa ccatctaatg tcatgcatac
     2221 tatatctttg gtgaagacaa ataaaaactg aaactaattg taacaactac ggcaggggtg
     2281 ttctatttaa agataggagg ggaagttgaa atgagctata tctcttttca acacctgttg
     2341 taattactgg cctgcctcct agttcataca gccatctgca cctactagtt agggtctcaa
     2401 tgtcctcaac catattgaga aatctgacca tggcccataa gaggagccac ccctgtctgg
     2461 ttctccctca cgtctcagcc tgcaatcaga agctgaagct gacctctggt atctgtcttt
     2521 gagcattctt cttgtgggta cattagtctt ttactgagaa aaaaaaaaaa gaatgactgc
     2581 atataaggct gacagcagag tgtaaatgaa tgccaatctg aggatctgaa acatttgtaa
     2641 aagattaatt tttatgtgaa gtataggact ttttgcctgc atgtattatg agcctacaga
     2701 ggccagaaga tgatgtcaga tcccgtgtac ctggagtttg taagtcacca tatgggtagg
     2761 tactgtgaac aaaatctagg tctttgaggg cataaagtgc tcttgtctga tgaaatacct
     2821 ctgcggctgc agtctgaatc attttacaat ataacagggt ttgcagaggt ctgtctgtga
     2881 agagggtgta cagcactggt agctggcatg tcagggacag aagtagagat caggtgctac
     2941 atgcaggtta tacagccttc ttggggattc tgcactcaca tctggccttc gagtgcctag
     3001 aatcaccctt cttgggtggt cctgcctggc ctcttatcct gttccatccc tacccccaca
     3061 atatcatttt gtactccccc tttactgaag ccacactcat ttcctggtga tagagttggc
     3121 tcacaccctt ttgtgttttc tgcctatgac catttcccct gctcccagca cttcatgttg
     3181 tcctaaagcc ttcagggcca gaaggagagt agaaggccct gtgttcctga gatagagctt
     3241 gccagggtca aaggttcaag ggggagggac atttcttaca tctttctcaa ataattctgg
     3301 gcacttggca gtcatatcca tatttgaata gtcaaaatgg gcccctcccc tacctcttcc
     3361 tgcctaggtc actcaggcct acagagttac agggtcctca accttctttc agatttatag
     3421 ctcttacctt tctctataat caaatctacc ccaatagcca gagtataaga tcatttctgc
     3481 acgggctgct catcttttca tcttttactc tatttggggg gtatttcccc agacttacag
     3541 gttccattag aaagtagcta gctttaagaa gaaatatatg ctatacccac actgccatcc
     3601 ttcttgctgc tattaccttg gaggtccagt gtggactgct gattggaaaa agctatagct
     3661 tttatattct gtagcacatc ctcttgtctt cctttcccat cctttcaact atacaaacct
     3721 gagggtgtgt gaattttcat ctcaccaaaa atggtgcaaa gctcatggtt tctattttac
     3781 tttatgggac actgagtttt cctttattga agaaacatgt acagacttca tgtgtgacaa
     3841 ctggcctagg acctagtacc tgtcaccctt ttagtggctg ctgagccctg ccaactacct
     3901 agtgcttgct gctgccctta aggccatgcc ctggagctct ttgataaagc agccctaaac
     3961 gtgctgcagc ctccagagtt tagaaatgaa aaaattttat ctttagcttc aaccttgaag
     4021 acacttctgt tctttaaagc tttaaggatc acagttccta tctggctatt ttacaatgaa
     4081 atcttatatt tgaagatgct gttggaatgt ccaatagaga cagctatttt tatgctgcaa
     4141 ttattgctgt tcacgtggtt ctggccctgt ttgtctatgt ggcctggaat gaaggctcat
     4201 ggtggcatgg aggcaaacag gactaaagtg aacatcacct tttgatcaca tgaaatttat
     4261 ttttggaata tgttaaacac ttctgggata ttgataataa atatattgtt tgaataaagt
     4321 tgaaaggaca tgtttaaaaa taaagaacta tgtacaaact g
//
