LOCUS       NM_172467               6538 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus zinc finger CCCH-type, antiviral 1-like (Zc3hav1l),
            mRNA.
ACCESSION   NM_172467
VERSION     NM_172467.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6538)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 6538)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK045287.1 and AC125530.4.
            
            On Feb 19, 2010 this sequence version replaced NM_172467.2.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK045287.1, AK051064.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN01164137
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2060              AK045287.1         2-2061
            2061-6538           AC125530.4         124028-128505       c
FEATURES             Location/Qualifiers
     source          1..6538
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 17.71 cM"
     gene            1..6538
                     /gene="Zc3hav1l"
                     /gene_synonym="B130055L09Rik; E430016P22Rik"
                     /note="zinc finger CCCH-type, antiviral 1-like"
                     /db_xref="GeneID:209032"
                     /db_xref="MGI:MGI:2443387"
     exon            1..396
                     /gene="Zc3hav1l"
                     /gene_synonym="B130055L09Rik; E430016P22Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             20..910
                     /gene="Zc3hav1l"
                     /gene_synonym="B130055L09Rik; E430016P22Rik"
                     /codon_start=1
                     /product="zinc finger CCCH-type antiviral protein 1-like"
                     /protein_id="NP_766055.1"
                     /db_xref="CCDS:CCDS20011.1"
                     /db_xref="GeneID:209032"
                     /db_xref="MGI:MGI:2443387"
                     /translation="MADLTLCAFLTKVLCAHGGRMFLQDLRGHVELSEAKLRAVLRRA
                     GPERFLLQEVELRDGPWDAEAEVAAGEGAGAGSGGGATACRVMAVSSARLCARYQRGE
                     CQGCDQLHLCRRHMLGKCPHRDCWSTCSLSHDIHTPINVQVLKSRGLFGLNEGQLRIL
                     LLQNDPCLFPEVCQMYNKGVDVLYGYCSLKDRCNKFHVCKSFVRGECPFQPCKRSHQL
                     IHAATLKLLEDQELSVSSVVNFQIISVYRHKKLHKMLEEKDHSASTEQPQGLGKQGAL
                     GAVEARPFLPARAQSPRKPQ"
     exon            397..532
                     /gene="Zc3hav1l"
                     /gene_synonym="B130055L09Rik; E430016P22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            533..794
                     /gene="Zc3hav1l"
                     /gene_synonym="B130055L09Rik; E430016P22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            795..6538
                     /gene="Zc3hav1l"
                     /gene_synonym="B130055L09Rik; E430016P22Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6440..6445
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zc3hav1l"
                     /gene_synonym="B130055L09Rik; E430016P22Rik"
                     /note="hexamer: AATAAA"
     polyA_site      6467
                     /gene="Zc3hav1l"
                     /gene_synonym="B130055L09Rik; E430016P22Rik"
                     /note="major polyA site"
ORIGIN      
        1 ggggacgcgc tggcgggcca tggcggacct cactctgtgc gcgttcctca ccaaggtgct
       61 gtgtgctcac ggcggccgca tgttcctgca ggacctgcgc ggccacgtgg agctgtcgga
      121 ggcgaagctg cgggccgtgc tgcggcgcgc gggtccagag cgcttcctgc tgcaggaggt
      181 ggagctgcgc gacggcccgt gggacgcaga ggccgaggtg gcggcgggcg agggcgcggg
      241 cgcgggctca ggcggcggcg ccacggcctg cagggtgatg gccgtgtcct ccgcgcgcct
      301 ctgcgcccgc taccagcgcg gggagtgtca gggctgcgac cagctgcact tgtgtcgccg
      361 ccacatgctg ggcaagtgcc cccaccgcga ctgctggtct acctgttctc tgtcccatga
      421 tatccacaca cctatcaacg tccaagtcct gaaaagccgg gggctttttg gcctcaatga
      481 agggcagctg cgaatcctgc ttttgcagaa cgacccctgc cttttcccag aggtctgtca
      541 gatgtacaac aaaggtgtcg atgtccttta tggctactgc agcctcaagg atagatgcaa
      601 caagtttcac gtgtgcaaat cctttgtgcg aggtgaatgc ccctttcagc cctgcaaacg
      661 ctcccaccag ctcatccatg ctgccaccct caagttgcta gaggaccaag aacttagtgt
      721 ttcaagcgtc gtgaatttcc agataatctc tgtctacaga cataagaagt tgcacaagat
      781 gcttgaagag aaagaccact cggcttctac tgagcaacca caaggccttg ggaaacaagg
      841 agccctcggg gctgtggaag ccaggccttt cctccctgcc cgtgctcagt cgcccaggaa
      901 gccccaataa acctgaacga gcttcggagg aagtgagaag cccctgtcca tcttggagga
      961 tcagaagcaa gacttttgct gagctgcagt ttttagccgg tctttctctc cctcacttag
     1021 tatcattggc aactgtaata cctacctcac aactaactga tcgccaggac ccagggtgga
     1081 aacgaaaata cacttgcggc tgagggctga ggttggacct ggagccagcc aagagagggt
     1141 aaattctgag cacgtaatcc agggtgaatc ctgaagctgt agtctctctc tgcagcccct
     1201 gaatgccttc gagcctcaat ggagggcagg tttcttctgc tgtctgctag gtcccgctgg
     1261 tgttttctag actccattta catagcttat gttatggaca tcacagtttg tgaactctgt
     1321 attgtttgtt acttgggctt atacttagtt ccttttttgc aaagaattgt taatataagt
     1381 gtaatcacct cccttattct gtaatatttc atactcctaa cagtgtttga atatctcatt
     1441 ttgtatctgt gcagtattga atttaaaagc caatttgtac ctttgcttgg cttgtaggtg
     1501 ctaaacaata ctgttttctg atacatattt ctttaactgt ctgtgtggat aacctctgtc
     1561 cctgctttct gtgtctcttg cttgattttg tgaatttccc atgttgcatt ttgtggcttg
     1621 ggccctctgt gctgtcatca atactgtgtt cataatattc aagtttctgg gtccatcctc
     1681 agtcagcaac ccagctaatg atctctggac tctgctcgga ggtttctacc tcaccccacc
     1741 cctctctcat cctctatcga gcctatcaga gctcagctgc tctatcctga aggatgtgtg
     1801 gttcactcct tccagttata tctccccggt gtggatggga cagaccatca ggaatccata
     1861 tataccttgc ccatttcgtg gtctctccct ccctcctccc tctcccctcc tctccttctc
     1921 cctctctctc ctccgtcctc cctcttccct cctcccttcc ctcctccctt cctccagcct
     1981 ctctgtaccc actcatcctg ttgttttcag tgtgtgcttt gctgatattt gttgtggtca
     2041 tgttccccaa tgtaactgtg taaaaagatt tgtgtttctt tccataacgt gacatttgag
     2101 aaataggagc aatttagtaa gttttcataa agccaaactt accttatttg gagaaacttt
     2161 tatcatgata ccaatggatc aaaggagagg agggatgtaa aagtgtcctt tccaaaccag
     2221 tttcctctta gtggacagta agctcgcgga cttagggctt ctcacttcag ttgtcagtaa
     2281 cagtacttct gagattgtgt tttatattct tttctttctt ttaaaattca agttgtgaca
     2341 tttttttcct agtggtattt gtgtgtgtgt gtgtgtgtgt gtgtgtgttt gtgtgtgtgt
     2401 ttgtgtgtgt gtttatgcat tgggatcaaa ccaagggcct tgcccatgtg aaacaaagtc
     2461 ctccaccagc aaggtacatc taagtcctgg actaaacttt aaagtaaaat tttagtccag
     2521 tcccagtggt gcaggccttt aatcccagca ctccagaggc agaggcaagc agatctgtga
     2581 gttcaagact gcctgatgta cagagtgagt tccaggctag tcagagctgc acagtgagac
     2641 cctgcctcaa aagaaattgc atttaattat tattactatt tacactctgt cattttccta
     2701 tatgtatttt gctgtaagcc atcttaaatc cttgatggga tggggtggct cagtgtgttc
     2761 tctttccatc aatagacgtg gtagctctta cagtggtagc tcttatagta ttgctttctc
     2821 atgtgtctca ccagcatgct ctcagatatg atgttcctgg tctgtaacca ttgttgcaac
     2881 attttattca agtccatagt atttcatttt aagttttagt tcttttggga atttagtcta
     2941 caaaattatc tttttgtgta tatgatactg ggaatgggcc tgtggctcat gagcactagg
     3001 caagtgtgct ctacctctga gctgtattct cagcactcaa attatgttat gtaagtgtta
     3061 ccagatcgag tctggctgct caccccatgc tgggcagata aagttaagag atgtggtact
     3121 gagggaagag ggtgatttta ttcacaaacc ttcgtagaaa ggaaggatgg gggtgtttgg
     3181 agcctgctcg ctggggagct aacttggggt cagtttacac tagtgggtga tggctgacct
     3241 tgggcactct ctcgcggtgc gtgggccaga gaatgcgcag ctctttgctt tgtcttgtgt
     3301 tttcatttct tcatgtctca gaaacagagc agtgtttcct tggactttac ttttcaaatt
     3361 agttccacag cacacaggga aatgactccc ggggtggaga ggtcctgagc cctccccccc
     3421 ccttgtgtaa tgagcgaact aggcttcatg atcacgcccc caaccgatag ttcaagtgga
     3481 gccttgtcac tttactgcac aaacttctct agctctaaca cgagaattct ctgaggactc
     3541 tcaggaatcg caaccggttt cctccagccc tccccccacc tcattctgag accattatcc
     3601 agtcatttga cttaagacaa caagttattg attgtcctta ttatcttttc ctcattccat
     3661 ggcaaatctg tttccaagtg ttggaagttc tttccccctc agaaaccttc taaagggtca
     3721 gttttcctta cctctctcca ccttcagaca ctgccctggt gcacaccccc acctctccct
     3781 gccttggtat acacacacac aaaactgtca ctgcctttgt gcacacttct cttatgtatt
     3841 tcataggcac attactcaat gatgtccagg ttaattgttg agtttttttg tttgttttgt
     3901 ttttgttttt tggtatgagg tgctgggtag gctcttatac ccatggtagc catggtagcc
     3961 gcatttaaat attgatatag ttggcctttg aagatttcat ttactctctc tcatttattt
     4021 gttgacacgg tctcatgcag cccgggctag tctcgaactc actatgtagc tcaggctggg
     4081 tttgaactcc ttatcccctg gcctctatct cccatgaggt gggggtgtcg gtgatgctac
     4141 cacatctgcc tctaaagtgg cttgtgtttc cctgctttta aatacgtttt acttatttac
     4201 tatacgtgtt gtgtttacgt tttacttatt tactatacgt gttgtgttta ggcttacgga
     4261 tgtagtgatg tgtgtggttc ggtgatgtat atgtggaggt cagaggtcgc ctccctgttg
     4321 tcagttctcg ccttccatat gtgggaggtg gctttagact tgtaatcctg ctgctcctta
     4381 agtgctaggg tcacaggtgt gggacacacc aggctctctc ctcttctccc tgcctccatt
     4441 ccagctgcct gatcttttgg aagcaaacct aaggatattg cagttctgtt tctcctgccg
     4501 aaattttcat cggcctccat cacgcagggc aagcatccta cgttaggatg cacaggggca
     4561 gagcaacagg taaatggggg taaggaagaa gggctgtggc aagctgtccc aacagtggtg
     4621 gttcctcact ttgggtttct atccggggat atggacccag atctccatat tgttccgttt
     4681 ttcagaagaa gccagaaata cagatttttg tgagatatga ctttggtgat taggtattac
     4741 cttttttggt tgagttttag gaacaaaaag gttagagtct gctgttgtgg aacatgccta
     4801 taattccagc acttaaaagc tggaggcaga aggagccaga gttgaaggcc agtcttcata
     4861 acacagtgag ttagaggctg gcccagctac tagaaaccat gactcaaaaa aacaaacaag
     4921 acagatgcca aaatttccac caacttgaat tttttggaat atatttcatc ttattactct
     4981 tgtttggttg gttagttgtt tttgtttttc ttttgaggca aggtattcta ggctggtctt
     5041 gaactcagta tgtagtctac attttggatc ctcctgcccc cacctcctaa gtgttgacat
     5101 tactggcatt tgctaccatg ccccacttac tcagtgctag ggattgaaga tgggacttga
     5161 tcatgtaagc aagcactctg cctcccgagg cacatcctca ggcctagccc tggactcagt
     5221 ctttaaatgc tgttgcctct tctgtaaaca taatcactac ttccctcact gtgcctcaaa
     5281 gcctggcaaa attacaattg tcaagagtca caataaccct tactgaccct gaaaaggtgg
     5341 tttgtagacc tccagcttat acctcacgct ccatccaaag ctttggtttt gagcaaaacc
     5401 attaattatt cctcgtggca atcctgacac ttagaagtta gaacacttct tgtcagatac
     5461 tgaataagtt gattcagaat atgctaattt tcattgtttt gtttgcttgg ttttggtttt
     5521 ataggtttta tgattttgtt ttgtttttga aacagggttt ctctatgtaa tggagccctg
     5581 gctgtcctag actcactctg tagaccaggc tggccttgaa ctcacagaag cctacctgtc
     5641 tctgtcattg cctttgtgcc ccacactcta cctgagtgct gggattaaag gtgtgtgcca
     5701 ccacttctgg ctctgatttt gttttttttt tttttattta aaaaaaaaaa aagtcagggt
     5761 ctcactgtag ccctgactgg cctggaactc attatgtaga ccaggtaggc tggaggcatc
     5821 tgctaggtct ataggtgttc atgttcacca ccacactcat gatcaccaca accctcagtt
     5881 caggtccttt atttaaaaaa aaatgcttac actttctttt tttcctattg agggtgctgt
     5941 atgatgcaag taattgaatc actgaagttt agagtcaact tctgttcatg aagtgggttg
     6001 cccatcaagg atgctctccg tcccacatca gtgtgtcccg attttcctca ctgtgttttt
     6061 ttatatatat ataaatttat tatgctagtt ctttcctgat tattttgtgt ttgtgttgct
     6121 attctctatg gggatctctc tggagtactg ctaactttta agatgaatgg ttagttgtaa
     6181 taactggaga tggcctgtct gtctgaatag aaaatcatag ctacaaagtg atgtgttatg
     6241 gagctccatc atttcatgtt taatacaaat aaaagtattt ttggtatttc ttcattagag
     6301 ttagttgtta gcttcactct attcttactt gttggaagct gaagacttga taaagtgact
     6361 cagtctttta atatcttcac accttgcatg attgattgca ttcaatgttt ttataatatt
     6421 gaaacatcct taaatttata ataaatcagc tctgtgtgac tatggcatat actcttggca
     6481 tttttttttt tctgtttgca attcactgag attcataaat aaaactcatt tgtatctt
//
