LOCUS       NM_145931               3771 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus zinc finger CCCH type containing 7 A (Zc3h7a),
            transcript variant 1, mRNA.
ACCESSION   NM_145931
VERSION     NM_145931.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3771)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3771)
  AUTHORS   Timmermans,S. and Libert,C.
  TITLE     Overview of inactivating mutations in the protein-coding genome of
            the mouse reference strain C57BL/6J
  JOURNAL   JCI Insight 3 (13), 121758 (2018)
   PUBMED   29997285
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3771)
  AUTHORS   Liang,J., Song,W., Tromp,G., Kolattukudy,P.E. and Fu,M.
  TITLE     Genome-wide survey and expression profiling of CCCH-zinc finger
            family reveals a functional module in macrophage activation
  JOURNAL   PLoS One 3 (8), e2880 (2008)
   PUBMED   18682727
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK040507.1, AK150952.1 and AV228180.1.
            
            On Jan 15, 2019 this sequence version replaced NM_145931.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the functional protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK167758.1, SRR1660817.222154.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1334              AK040507.1         1-1334
            1335-3764           AK150952.1         1306-3735
            3765-3771           AV228180.1         230-236
FEATURES             Location/Qualifiers
     source          1..3771
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 6.35 cM"
     gene            1..3771
                     /gene="Zc3h7a"
                     /gene_synonym="A430104C18Rik; HSPC055; Zc3h7; Zc3hdc7"
                     /note="zinc finger CCCH type containing 7 A"
                     /db_xref="GeneID:106205"
                     /db_xref="MGI:MGI:2445044"
     exon            1..122
                     /gene="Zc3h7a"
                     /gene_synonym="A430104C18Rik; HSPC055; Zc3h7; Zc3hdc7"
                     /inference="alignment:Splign:2.1.0"
     exon            123..224
                     /gene="Zc3h7a"
                     /gene_synonym="A430104C18Rik; HSPC055; Zc3h7; Zc3hdc7"
                     /inference="alignment:Splign:2.1.0"
     CDS             157..3069
                     /gene="Zc3h7a"
                     /gene_synonym="A430104C18Rik; HSPC055; Zc3h7; Zc3hdc7"
                     /note="zinc finger CCCH type domain containing 7"
                     /codon_start=1
                     /product="zinc finger CCCH domain-containing protein 7A"
                     /protein_id="NP_666043.2"
                     /db_xref="CCDS:CCDS49762.1"
                     /db_xref="GeneID:106205"
                     /db_xref="MGI:MGI:2445044"
                     /translation="MSSVSEERRKRQHSIKEGLQFIQSPLSYPGTQEQYAVYLHALVR
                     NLFNEGNDIYRECDWRGSLIQYSEALSIANYAKSEEILIPTEIIEKLRINRIACYSNM
                     GLRDEVLEDCNAVLSVNASNCKALYRKAKALSDLGHYREAYDAVAKCSLAVPQDEHVI
                     KLTQELAQKLGFKIRKAYVRAEHLLKAVPGDGAPKAVNYSVEDIEPDLLAPRQEALSV
                     ASLPTSSFSHVIGSELASVPIMPVTSVLQLQVDESPLPSTVFANGGKIPFTISDAFLD
                     DDIVLGDEIDALLDSAPETNDAVMSSTLVRGPLPTASAAPSLPFRTQSLLGTLPMGTR
                     YPEPSFADFFPPLTSSLEEFYSSLNSFSVTESKRDLCTSTAREGTPLNNSNSSLLLMN
                     GPGNLLASENFLGITSQPRNDFGNFFGSVIAKPFSSGTPRHPLEGTHELRQACQICFV
                     KSGPKLMDFTYHANVDHKCKKDILIGRIKNVEDKSWKKIRPRPTKTNYEGPYYICKDV
                     AADDECRYPGHCTFAYCQEEIDVWTLERKGAFSREAFFGGNGKINLTVVRILQEHHGE
                     FTFLCEKCFDHKPRMISKRNKDNSTACSHPVTKHEFEDNKCLVHILRETTVKYSKIRS
                     FHKQCQFDICRHEVRYGCVREDECFYAHSLIELKVWIMQSERGISHDDIAQQSKQYWR
                     SLQASMPGVQVLGNQIMPGLLNMEIKFVCAQCLRNGQVIEPDRNRKYCSAKAQHSWTK
                     ERRAMRAMSFERKKWMNIRPLPTKKQMPLQFDLCNHIANRKKCQYVGNCSFAHSPEER
                     EVWTYMKDNKIHDIEQFYELWLKNQKTEKSDETASHCSKENGKQIHMPTDYAEVTVDF
                     HCWMCGKNCNSEKQWQDHISSEKHKEKVFHTEDDQYCWQHRFPTGYFSICERYINGSC
                     TEGSSCKFAHGNAELHEWEERRKALQMKFKKARKDHLIAPNDNDFGKYSFLFKDLK"
     exon            225..264
                     /gene="Zc3h7a"
                     /gene_synonym="A430104C18Rik; HSPC055; Zc3h7; Zc3hdc7"
                     /inference="alignment:Splign:2.1.0"
     exon            265..462
                     /gene="Zc3h7a"
                     /gene_synonym="A430104C18Rik; HSPC055; Zc3h7; Zc3hdc7"
                     /inference="alignment:Splign:2.1.0"
     exon            463..621
                     /gene="Zc3h7a"
                     /gene_synonym="A430104C18Rik; HSPC055; Zc3h7; Zc3hdc7"
                     /inference="alignment:Splign:2.1.0"
     exon            622..702
                     /gene="Zc3h7a"
                     /gene_synonym="A430104C18Rik; HSPC055; Zc3h7; Zc3hdc7"
                     /inference="alignment:Splign:2.1.0"
     exon            703..741
                     /gene="Zc3h7a"
                     /gene_synonym="A430104C18Rik; HSPC055; Zc3h7; Zc3hdc7"
                     /inference="alignment:Splign:2.1.0"
     exon            742..775
                     /gene="Zc3h7a"
                     /gene_synonym="A430104C18Rik; HSPC055; Zc3h7; Zc3hdc7"
                     /inference="alignment:Splign:2.1.0"
     exon            776..1056
                     /gene="Zc3h7a"
                     /gene_synonym="A430104C18Rik; HSPC055; Zc3h7; Zc3hdc7"
                     /inference="alignment:Splign:2.1.0"
     exon            1057..1261
                     /gene="Zc3h7a"
                     /gene_synonym="A430104C18Rik; HSPC055; Zc3h7; Zc3hdc7"
                     /inference="alignment:Splign:2.1.0"
     exon            1262..1326
                     /gene="Zc3h7a"
                     /gene_synonym="A430104C18Rik; HSPC055; Zc3h7; Zc3hdc7"
                     /inference="alignment:Splign:2.1.0"
     exon            1327..1513
                     /gene="Zc3h7a"
                     /gene_synonym="A430104C18Rik; HSPC055; Zc3h7; Zc3hdc7"
                     /inference="alignment:Splign:2.1.0"
     exon            1514..1675
                     /gene="Zc3h7a"
                     /gene_synonym="A430104C18Rik; HSPC055; Zc3h7; Zc3hdc7"
                     /inference="alignment:Splign:2.1.0"
     exon            1676..1872
                     /gene="Zc3h7a"
                     /gene_synonym="A430104C18Rik; HSPC055; Zc3h7; Zc3hdc7"
                     /inference="alignment:Splign:2.1.0"
     exon            1873..1973
                     /gene="Zc3h7a"
                     /gene_synonym="A430104C18Rik; HSPC055; Zc3h7; Zc3hdc7"
                     /inference="alignment:Splign:2.1.0"
     exon            1974..2155
                     /gene="Zc3h7a"
                     /gene_synonym="A430104C18Rik; HSPC055; Zc3h7; Zc3hdc7"
                     /inference="alignment:Splign:2.1.0"
     exon            2156..2232
                     /gene="Zc3h7a"
                     /gene_synonym="A430104C18Rik; HSPC055; Zc3h7; Zc3hdc7"
                     /inference="alignment:Splign:2.1.0"
     exon            2233..2366
                     /gene="Zc3h7a"
                     /gene_synonym="A430104C18Rik; HSPC055; Zc3h7; Zc3hdc7"
                     /inference="alignment:Splign:2.1.0"
     exon            2367..2472
                     /gene="Zc3h7a"
                     /gene_synonym="A430104C18Rik; HSPC055; Zc3h7; Zc3hdc7"
                     /inference="alignment:Splign:2.1.0"
     exon            2473..2581
                     /gene="Zc3h7a"
                     /gene_synonym="A430104C18Rik; HSPC055; Zc3h7; Zc3hdc7"
                     /inference="alignment:Splign:2.1.0"
     exon            2582..2715
                     /gene="Zc3h7a"
                     /gene_synonym="A430104C18Rik; HSPC055; Zc3h7; Zc3hdc7"
                     /inference="alignment:Splign:2.1.0"
     exon            2716..2879
                     /gene="Zc3h7a"
                     /gene_synonym="A430104C18Rik; HSPC055; Zc3h7; Zc3hdc7"
                     /inference="alignment:Splign:2.1.0"
     exon            2880..3771
                     /gene="Zc3h7a"
                     /gene_synonym="A430104C18Rik; HSPC055; Zc3h7; Zc3hdc7"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3741..3746
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zc3h7a"
                     /gene_synonym="A430104C18Rik; HSPC055; Zc3h7; Zc3hdc7"
                     /note="hexamer: AATAAA"
     polyA_site      3765
                     /gene="Zc3h7a"
                     /gene_synonym="A430104C18Rik; HSPC055; Zc3h7; Zc3hdc7"
                     /note="major polyA site"
ORIGIN      
        1 ggcagctgcg gtgggtcgcc cagggaagct gcgagactgt gagagctctt gagccggtga
       61 acgcacatcc cgctgtcgcc tccgcactcc gcgcccctcg gctcctgggt gccgccccgc
      121 agattgctca tttagcaagt ggatgtgcag ggtaacatgt ccagtgtgtc cgaggagaga
      181 agaaagaggc agcacagcat aaaggaaggt ctacagttca tccagtctcc gctgtcatat
      241 cctgggaccc aggagcagta tgcggtgtat ttgcatgctc tcgtgagaaa tctttttaat
      301 gaaggaaatg atatttatcg ggaatgtgac tggcgtggct ctctaattca gtactcagaa
      361 gctttgagta tagctaatta tgcaaagtct gaagaaattt taattcctac agaaatcatt
      421 gaaaaacttc gtataaatcg tattgcttgc tattctaata tgggcctccg tgatgaagtt
      481 ttagaagact gtaacgctgt cctcagtgtt aatgccagta actgcaaggc tctgtatcgg
      541 aaggctaagg ctctaagtga cttagggcac tacagagagg cctacgacgc tgtggcaaag
      601 tgctccttag cagtgcctca ggatgaacat gtaataaaat taactcaaga attagctcag
      661 aaattgggat ttaaaataag gaaagcatat gttagagctg agcacttact gaaagcagtt
      721 cctggggatg gggctcccaa ggctgtgaac tattctgtgg aagatattga gccagatttg
      781 ttagccccaa ggcaagaagc actttcggtt gcctcccttc ctacatccag tttttctcat
      841 gtcattggga gtgagctggc ctctgttcct attatgccgg taacttctgt tttgcaactg
      901 caagtggatg agagtcctct gccatccaca gtgtttgcaa atggagggaa gatccccttc
      961 accatatccg atgcttttct ggatgatgac attgtccttg gggatgaaat agatgctctt
     1021 cttgattctg ccccagaaac aaatgatgct gttatgtcct ccactctggt cagaggaccc
     1081 ctcccgactg ccagtgcagc tccgagcttg cccttcagga cacaatccct gcttggaacc
     1141 ttgcccatgg gtacaaggta tcctgagccc tcctttgcag acttttttcc acctctgact
     1201 tcatccttgg aagaatttta ctcttcttta aattcatttt cagtgactga atccaaacga
     1261 gatctgtgca cctcaactgc tagagaggga acaccgctta acaacagtaa ttcctccctt
     1321 ttacttatga atggaccagg taatttgttg gcctctgaaa attttctggg aattacaagt
     1381 cagcctagaa atgactttgg aaactttttt ggaagtgtga tcgctaaacc attttcatca
     1441 gggactccta ggcatcccct cgaaggaacc cacgagctga ggcaagcttg ccagatctgc
     1501 tttgtaaaat caggccctaa gttaatggat ttcacatacc atgctaatgt agatcataaa
     1561 tgtaagaaag atattttaat tggtaggata aaaaatgttg aagataaatc atggaaaaaa
     1621 atacgtccaa gaccaacaaa aacaaattat gaaggaccat attatatatg caaagatgtt
     1681 gctgcagatg atgaatgccg atatcctggc cactgtacat ttgcttattg ccaagaagag
     1741 atagatgtgt ggaccctgga aagaaaaggg gcattcagtc gagaggcttt ctttgggggc
     1801 aatggaaaga tcaaccttac tgtggtcaga attctccaag agcatcatgg agagtttaca
     1861 ttcctttgtg agaaatgttt tgatcataaa cctagaatga taagtaaaag aaataaagat
     1921 aattccactg cctgctctca ccccgtcaca aagcatgaat ttgaggacaa taagtgcctt
     1981 gtccacattt tgagagagac cacagtaaaa tattccaaaa tacgttcttt tcataaacaa
     2041 tgtcaatttg atatttgtcg acatgaagtt cgttatggct gcgtgaggga agatgagtgc
     2101 ttctatgccc atagtcttat tgaactgaaa gtctggataa tgcaaagtga aagaggtatc
     2161 tcccatgatg atattgctca acaatccaaa caatattgga gaagtttgca agcaagcatg
     2221 ccgggagtgc aggtccttgg taatcaaata atgcctggat tacttaacat ggagataaag
     2281 tttgtatgtg ctcagtgtct gagaaatggc caagtcattg aaccagacag gaacagaaag
     2341 tactgcagtg ccaaagcaca gcattcgtgg accaaagaac gtcgtgcaat gagagcgatg
     2401 tcttttgaac gtaagaagtg gatgaacatc cgtcctctcc ccacaaagaa acaaatgcct
     2461 ttacagtttg atctatgcaa ccatattgct aatagaaaaa agtgtcagta tgttggcaac
     2521 tgttcctttg ctcatagtcc agaggagcgg gaagtgtgga cttacatgaa ggataacaaa
     2581 atacatgata tagagcaatt ttatgaactc tggctgaaga accaaaaaac tgaaaaaagt
     2641 gatgagacag ccagtcactg tagcaaagaa aacgggaagc agatccatat gccaacagac
     2701 tatgctgaag tcactgtgga cttccactgc tggatgtgtg ggaagaactg taacagtgag
     2761 aagcaatggc aagaccacat ctcctctgag aagcacaagg agaaggtttt ccacactgag
     2821 gatgaccagt actgctggca gcaccgcttc cccactgggt acttcagtat ttgtgagagg
     2881 tatataaatg gctcctgcac agaaggaagc agctgtaaat ttgcacatgg aaatgctgaa
     2941 cttcatgaat gggaagaaag aagaaaggcc ctacagatga aattcaagaa agcacggaaa
     3001 gatcacttaa ttgccccaaa tgataatgac tttggaaaat atagtttttt gtttaaagat
     3061 ttaaagtaat atgctggctt ttatgtaacc caatcagagc actgaccaga aaaattgcaa
     3121 gtgttgagag gcacacagca gaagagctgc agatttctgc ttgattggca tctatcgttc
     3181 ctcctgagca gcaacccaca gtagatagga aaaaggctgt ttgacaggcc tggctaagct
     3241 cttgcggagc cactggcatc agatggcgaa gggacttgct gccaggttgc tgtctgttgg
     3301 acagaagctc ggatgaggtg tgctggggaa ggggtaaggt tgaggatgac tctgaggtca
     3361 gagccacagc agtgagtgta atgcacagtg ggatcggagt acatgatgga tgaaattcct
     3421 tatgtgtttt agtggaatga agttatttaa tataataaag tctgctactt atctgtatgt
     3481 aggttgctaa aaaggatttt cttaactcag atttttaagc caaataacca tttagcacta
     3541 gtgtctgtta aatgggtttt tctgtatttg tctgtctcac tgtggcaagg gaaccgatga
     3601 tgatcatgca catcaatatt tggaaaataa tcaattgaca caaattttat ttcttggtct
     3661 tttgctgttt aaataatgat ttttgaaaga ttcaacttgt actgctggta ttgtgtagtg
     3721 tatggaccaa tattgcttgt aataaaagat cttacataga gatgactttc a
//
