LOCUS       NM_198631               6107 bp    mRNA    linear   ROD 09-JUL-2024
DEFINITION  Mus musculus zinc finger CCCH-type containing 4 (Zc3h4), transcript
            variant 2, mRNA.
ACCESSION   NM_198631 XM_284266
VERSION     NM_198631.2
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6107)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 6107)
  AUTHORS   Zhou,Z., Ye,Q., Ren,H., Zhang,Y., Han,B., Yao,H. and Bai,Y.
  TITLE     CircDYM attenuates microglial apoptosis via CEBPB/ZC3H4 axis in
            LPS-induced mouse model of depression
  JOURNAL   Int J Biol Macromol 254 (Pt 3), 127922 (2024)
   PUBMED   37944732
  REMARK    GeneRIF: CircDYM attenuates microglial apoptosis via CEBPB/ZC3H4
            axis in LPS-induced mouse model of depression.
REFERENCE   3  (bases 1 to 6107)
  AUTHORS   Jiang,R., Zhou,Y., Gao,Q., Han,L. and Hong,Z.
  TITLE     ZC3H4 governs epithelial cell migration through ROCK/p-PYK2/p-MLC2
            pathway in silica-induced pulmonary fibrosis
  JOURNAL   Environ Toxicol Pharmacol 104, 104301 (2023)
   PUBMED   37866415
  REMARK    GeneRIF: ZC3H4 governs epithelial cell migration through
            ROCK/p-PYK2/p-MLC2 pathway in silica-induced pulmonary fibrosis.
REFERENCE   4  (bases 1 to 6107)
  AUTHORS   Ghafoor,H., Chu,H., Huang,J., Chen,M., Wang,S., Wang,J. and Chao,J.
  TITLE     ZC3H4 promotes pulmonary fibrosis via an ER stress-related positive
            feedback loop
  JOURNAL   Toxicol Appl Pharmacol 435, 115856 (2022)
   PUBMED   34979141
  REMARK    GeneRIF: ZC3H4 promotes pulmonary fibrosis via an ER stress-related
            positive feedback loop.
REFERENCE   5  (bases 1 to 6107)
  AUTHORS   Austenaa,L.M.I., Piccolo,V., Russo,M., Prosperini,E., Polletti,S.,
            Polizzese,D., Ghisletti,S., Barozzi,I., Diaferia,G.R. and Natoli,G.
  TITLE     A first exon termination checkpoint preferentially suppresses
            extragenic transcription
  JOURNAL   Nat Struct Mol Biol 28 (4), 337-346 (2021)
   PUBMED   33767452
REFERENCE   6  (bases 1 to 6107)
  AUTHORS   Suto,J.
  TITLE     Coincidence of loci for glucosuria and obesity in type 2
            diabetes-prone KK-Ay mice
  JOURNAL   Med Sci Monit 14 (2), CR65-CR74 (2008)
   PUBMED   18227763
REFERENCE   7  (bases 1 to 6107)
  AUTHORS   Suto,J. and Sekikawa,K.
  TITLE     Confirmation and characterization of murine body weight QTLs, Bwq1
            and Bwq2, identified in C57BL/6J x KK-Ay/a F2-Ay/a mice
  JOURNAL   J Vet Med Sci 66 (9), 1039-1045 (2004)
   PUBMED   15472465
REFERENCE   8  (bases 1 to 6107)
  AUTHORS   Rogers,M.S., Rohan,R.M., Birsner,A.E. and D'Amato,R.J.
  TITLE     Genetic loci that control the angiogenic response to basic
            fibroblast growth factor
  JOURNAL   FASEB J 18 (10), 1050-1059 (2004)
   PUBMED   15226265
  REMARK    Erratum:[FASEB J. 2015 Jan;29(1):354-5]
REFERENCE   9  (bases 1 to 6107)
  AUTHORS   Chae,T.H., Allen,K.M., Davisson,M.T., Sweet,H.O. and Walsh,C.A.
  TITLE     Mapping of the mouse hyh gene to a YAC/BAC contig on proximal
            Chromosome 7
  JOURNAL   Mamm Genome 13 (5), 239-244 (2002)
   PUBMED   12016511
REFERENCE   10 (bases 1 to 6107)
  AUTHORS   Suto,J., Matsuura,S., Imamura,K., Yamanaka,H. and Sekikawa,K.
  TITLE     Genetics of obesity in KK mouse and effects of A(y) allele on
            quantitative regulation
  JOURNAL   Mamm Genome 9 (7), 506-510 (1998)
   PUBMED   9657845
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ101946.1, BY167917.1, BC057627.1, AC164880.3, CF538051.1,
            AK129275.1, CN667093.1 and BC060274.1.
            
            On Nov 28, 2007 this sequence version replaced NM_198631.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data because no single transcript was available
            for the full length of the gene. The extent of this transcript is
            supported by transcript alignments and orthologous human data.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849375,
                              SAMN00849379 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-106               CJ101946.1         6-111
            107-111             BY167917.1         94-98
            112-424             BY167917.1         161-473
            425-675             BC057627.1         370-620
            676-786             AC164880.3         88271-88381         c
            787-1512            CF538051.1         1-726
            1513-2126           AK129275.1         637-1250
            2127-2375           CN667093.1         47-295
            2376-6045           AK129275.1         1251-4920
            6046-6107           BC060274.1         3965-4026
FEATURES             Location/Qualifiers
     source          1..6107
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 9.03 cM"
     gene            1..6107
                     /gene="Zc3h4"
                     /gene_synonym="Bwq1; Gm768; Kiaa1064-hp"
                     /note="zinc finger CCCH-type containing 4"
                     /db_xref="GeneID:330474"
                     /db_xref="MGI:MGI:2682314"
     exon            1..111
                     /gene="Zc3h4"
                     /gene_synonym="Bwq1; Gm768; Kiaa1064-hp"
                     /inference="alignment:Splign:2.1.0"
     CDS             98..3865
                     /gene="Zc3h4"
                     /gene_synonym="Bwq1; Gm768; Kiaa1064-hp"
                     /note="isoform 2 is encoded by transcript variant 2; zinc
                     finger CCCH domain-containing protein 4"
                     /codon_start=1
                     /product="zinc finger CCCH domain-containing protein 4
                     isoform 2"
                     /protein_id="NP_941033.2"
                     /db_xref="CCDS:CCDS52040.1"
                     /db_xref="GeneID:330474"
                     /db_xref="MGI:MGI:2682314"
                     /translation="MLRGREDGELEEGELEDDGAEEVQDPPGGQERSRKEKGEKHHSD
                     SEEEKSHRRLKRKRKKEREKEKRRSKKRRKSKHKRHASSSDDFSDFSDDSDFSPSEKS
                     HRKYRDYSPPYAPSHQQYSSSHNAPLPKKSYSKMDSKGYSMYEDYENEQYGEYEGDEE
                     EDMGKEDYDDFTKELNQYRRAKEGSSRGRGSRGRGRGYRGRGSRGGSRGRGMGRGSRG
                     RGRGSMGEHPEDEEDLYEEEIEYGESEEPMGDDDYDDYSKELNQYRRSKDSRGRGLSR
                     GRGRGSRGGRGKGMGRGRGRGGRGGMSKGGMNDDEDFYDDDMGDGGGGSYRRSDHDKP
                     HQQSDKKGKVICKYFVEGRCTWGDHCNFSHDIELPKKRELCKFYITGFCARAENCPYM
                     HGDFPCKLYHTTGNCINGDDCMFSHDPLTEETRELLDKMLADDAEAGAEDEKEVEELK
                     KQGINPLPKPPPGVGLLPTPPRPPGPPAPTSPNGRPMQGGPPPPPPPPPPPPGPPQMS
                     LPTHEPLSPQQLQQDMYNKKIPSLFEIVVRPTGQLAEKLGVRFPGPGGPSGPMGPGPN
                     MGPPGPMGGPMHPDMHPDMHPDMHPDMHPDMHPDMHPDMHPDMHPDMPMGPGMNPGPP
                     MGPGGPPMMPYGPGDSPHSGMMPPIPPAQNFYENFYPQQEGMEMEPGLVGDAEDYGHY
                     EELPGQPGEPLFPEHPLEPDSFPEGGPPGRPKAGAGVPDFLPSAQRALYLRIQQKQQE
                     EERARRLAESSKQDRENEEGDTGNWYSSDEDEGGSSVTSILKTLRQQTSSRPQASVGE
                     PSSSGLGDPRLQKGHPTGSRLSDPRLSRDPRLSRHAETSGGSGPGDSGPSDPRLARAL
                     PTSKAEGSLHSSPAGPSSSKGQPPAEEEEGERALREKAVNIPLDPLPGHPLRDPRSQL
                     QQFSHIKKDVTLSKPSFARTVLWNPEDLIPLPIPKQDVPPVPAALQSLPALDPRLHRS
                     TPPGPPNTRQRPGSTDPSTSGSNLPDFELLSRILKTVNVNTPGQSEKPSDPRVRKTPT
                     DPRLQKPADPVAASRAAKPCPTEASPPAASPSGDSSPPATAPYDPRVLAAGGLGQGSS
                     SGQSSVLSGISLYDPRTPNAGGKTAEPASDTSAQPKGPEGNGKGSASKAKEPPFVRKS
                     ALEQPETGKASTDGATATDRYNSYNRPRPKATAAPTAASSTPPPEGATPQPGVHNLPV
                     PTLFGTVKPAPKTGTGSPFAGNSPAREGEQDAGSLKDVFKGFDPTASPFCQ"
     exon            112..331
                     /gene="Zc3h4"
                     /gene_synonym="Bwq1; Gm768; Kiaa1064-hp"
                     /inference="alignment:Splign:2.1.0"
     exon            332..442
                     /gene="Zc3h4"
                     /gene_synonym="Bwq1; Gm768; Kiaa1064-hp"
                     /inference="alignment:Splign:2.1.0"
     exon            443..665
                     /gene="Zc3h4"
                     /gene_synonym="Bwq1; Gm768; Kiaa1064-hp"
                     /inference="alignment:Splign:2.1.0"
     exon            666..817
                     /gene="Zc3h4"
                     /gene_synonym="Bwq1; Gm768; Kiaa1064-hp"
                     /inference="alignment:Splign:2.1.0"
     exon            818..914
                     /gene="Zc3h4"
                     /gene_synonym="Bwq1; Gm768; Kiaa1064-hp"
                     /inference="alignment:Splign:2.1.0"
     exon            915..1054
                     /gene="Zc3h4"
                     /gene_synonym="Bwq1; Gm768; Kiaa1064-hp"
                     /inference="alignment:Splign:2.1.0"
     exon            1055..1165
                     /gene="Zc3h4"
                     /gene_synonym="Bwq1; Gm768; Kiaa1064-hp"
                     /inference="alignment:Splign:2.1.0"
     exon            1166..1277
                     /gene="Zc3h4"
                     /gene_synonym="Bwq1; Gm768; Kiaa1064-hp"
                     /inference="alignment:Splign:2.1.0"
     exon            1278..1387
                     /gene="Zc3h4"
                     /gene_synonym="Bwq1; Gm768; Kiaa1064-hp"
                     /inference="alignment:Splign:2.1.0"
     exon            1388..1746
                     /gene="Zc3h4"
                     /gene_synonym="Bwq1; Gm768; Kiaa1064-hp"
                     /inference="alignment:Splign:2.1.0"
     exon            1747..2126
                     /gene="Zc3h4"
                     /gene_synonym="Bwq1; Gm768; Kiaa1064-hp"
                     /inference="alignment:Splign:2.1.0"
     exon            2127..2375
                     /gene="Zc3h4"
                     /gene_synonym="Bwq1; Gm768; Kiaa1064-hp"
                     /inference="alignment:Splign:2.1.0"
     exon            2376..6051
                     /gene="Zc3h4"
                     /gene_synonym="Bwq1; Gm768; Kiaa1064-hp"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6025..6030
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zc3h4"
                     /gene_synonym="Bwq1; Gm768; Kiaa1064-hp"
                     /note="hexamer: ATTAAA"
     polyA_site      6050
                     /gene="Zc3h4"
                     /gene_synonym="Bwq1; Gm768; Kiaa1064-hp"
                     /note="major polyA site"
ORIGIN      
        1 tttctcgctt cgctttctct cccggcctca tgcgttgccc cccctcgcgg cgttcgcccg
       61 ctctccctcg ctctcgctct gtcttttttt gggcgccatg ctgaggggaa gggaagatgg
      121 tgagttggaa gaaggtgaac tggaagacga cggggctgag gaggtccagg acccccctgg
      181 aggacaagag aggagtcgga aggagaaggg ggagaagcac cacagcgact ctgaggagga
      241 gaagtctcac cggaggctga agcggaagcg gaagaaggag cgggagaagg aaaagaggcg
      301 ctcgaagaaa aggcggaaat ctaagcacaa acgccatgct tcctccagcg atgacttctc
      361 ggacttctca gatgactcag atttcagccc cagtgagaag agtcaccgca agtaccggga
      421 ctatagtccc ccatacgcac catcccacca gcagtactcc tcgtcacaca acgcacccct
      481 gcccaagaag tcctactcca agatggatag caagggctac agcatgtatg aggactacga
      541 gaatgagcag tatggggagt acgaggggga tgaagaggag gacatgggta aggaagacta
      601 tgacgacttc accaaagaac tgaaccagta ccggcgtgcc aaggagggca gcagccgggg
      661 cagaggtagc cgaggccgag gcaggggcta caggggccgt gggagtcgag gaggatctcg
      721 aggccgaggc atgggcaggg gcagcagagg ccgaggccga ggctccatgg gagagcaccc
      781 agaggacgaa gaggacttgt atgaagagga gatagagtat ggagaaagtg aggagcccat
      841 gggagacgat gattacgatg actattccaa ggagctgaac cagtaccgca ggtccaagga
      901 cagccgaggt cgagggttga gtcgaggccg aggccgcggt tcccgaggag gccgagggaa
      961 ggggatgggc cggggcagag gtcgaggcgg cagaggtgga atgagcaagg gcggaatgaa
     1021 tgatgacgag gacttctacg atgatgacat gggtgacggt ggtggcggaa gctaccggcg
     1081 gagtgatcat gacaagcccc accagcagtc tgacaagaaa ggcaaagtca tctgcaaata
     1141 ctttgtggag ggacgatgca cttggggaga ccactgcaat tttagccacg acattgagct
     1201 accgaagaag cgagagttgt gcaaatttta catcacgggg ttctgtgctc gtgctgagaa
     1261 ctgcccctac atgcatggtg actttccgtg taaattatac cacaccactg ggaactgcat
     1321 caatggtgac gactgcatgt tctcccatga cccgctgaca gaagagacac gagagctcct
     1381 agataagatg ttggctgatg atgcagaagc aggcgctgag gacgagaagg aggtagagga
     1441 gctgaagaag cagggcatca accctttgcc caagccacct cctggtgtag ggctcctgcc
     1501 tactcctcca cggccccctg ggcctccagc ccccacctct cctaatggca ggcccatgca
     1561 aggtggccct cctccaccac caccacctcc tccaccacct cctggacctc ctcagatgtc
     1621 cctgccaaca catgagccac tgtctccaca acagttacag caggacatgt acaacaagaa
     1681 gatcccctct ttgtttgaga ttgtggtgcg gcccacgggg cagctagctg agaagctggg
     1741 cgtgaggttc cctggacctg gtggaccctc ggggccaatg ggtcctggcc ccaacatggg
     1801 acccccaggg ccaatggggg gacccatgca tcctgacatg caccctgaca tgcacccaga
     1861 catgcacccc gacatgcacc ctgacatgca ccccgacatg caccccgaca tgcaccctga
     1921 catgcatcct gacatgccaa tgggtcctgg catgaaccct ggccctccca tgggtcctgg
     1981 tggcccccca atgatgccct atggtcctgg agactcccca cattctggaa tgatgcctcc
     2041 tatcccgcca gcccagaact tctatgagaa cttctacccg cagcaagagg gcatggaaat
     2101 ggagcctggt cttgttggag atgcagagga ctacgggcac tacgaagagc tgccggggca
     2161 gcctggggag cccctcttcc ctgagcaccc tctggagcct gacagcttcc ccgagggagg
     2221 gcccccaggc cggccgaagg caggcgccgg tgtacccgac ttcttgccct cggctcagag
     2281 ggccctgtac ctgaggatcc agcagaagca gcaggaggag gagagagcga ggaggctggc
     2341 tgagagcagc aagcaggacc gggagaatga ggaaggtgac actggaaact ggtactcaag
     2401 tgatgaggat gaagggggaa gcagtgtcac atccatcctg aagaccttga ggcaacagac
     2461 gtcaagccga ccccaggctt cagttgggga accgagcagc agtgggctgg gggatccccg
     2521 tctccagaag ggacacccca caggaagtcg gctgtctgac ccccgcctca gccgggaccc
     2581 cagactcagc cgccatgcag agacttcagg agggtctggc ccaggggact cggggccctc
     2641 tgaccctcgg ttggctcgtg ctctgcccac ctccaaggct gaaggcagcc ttcattccag
     2701 ccctgcaggc cccagcagtt caaaaggaca gccccctgca gaagaggagg aaggggagag
     2761 agccttgcgt gaaaaggcgg tgaacattcc cctggaccct ctgcctggac acccactacg
     2821 ggaccctcgc tctcagctgc aacagttcag ccacatcaag aaggatgtga ccctgagcaa
     2881 gccgagcttt gctcgcacag tgctctggaa ccctgaagac ctgatccccc tgcccatccc
     2941 caagcaggac gtgcccccag tgcctgctgc cctgcagtcc ctacctgctc tagatcctag
     3001 gctacaccgt tccacacccc ctgggcctcc aaacacccgg cagcgtccag gctccacaga
     3061 tcccagcacc tctggctcta acctacctga ctttgaactc ctctctcgaa tcctcaagac
     3121 cgtcaatgtc aatacccctg gtcagagtga aaagcccagt gatccgaggg tgcggaagac
     3181 ccctactgac cccagattac agaagccagc agatcctgtg gcagcctccc gtgcagccaa
     3241 gccctgtccc actgaagcat cgcctcctgc tgccagccca agcggggatt catccccacc
     3301 ggccacggct ccctatgacc cccgagtgct ggctgctggt ggcttgggcc agggcagcag
     3361 cagcgggcag agcagtgtgc tgagtggtat cagcttatat gacccaagga ctcccaatgc
     3421 aggtggcaaa actgcagagc cagcttctga cacaagtgct cagcccaagg gtcctgaggg
     3481 caatggcaag ggctcagcct ccaaggcaaa agagcctccg tttgtccgaa agtctgccct
     3541 ggagcagcca gagacaggga aggccagcac agatggggcc acagccacgg acagatacaa
     3601 tagctacaac cggccccggc ccaaggccac agcagccccc actgctgcct catccacccc
     3661 gccccctgag ggggccacac cccagcctgg ggtacacaac ctgccagtgc ccactctctt
     3721 tgggactgta aagccggccc ccaaaacagg cacagggagc ccctttgctg gcaacagccc
     3781 tgcccgtgag ggtgagcagg atgcaggatc cctgaaggac gtttttaaag gctttgaccc
     3841 cacagcctcc cccttctgcc agtagtgtca ctgggggcca gtgctccctc cactccacca
     3901 ccctcccagg gtgacattta agggcagcaa ccagagttac aggcgggagg tggggcaggt
     3961 gggcagggtg ttctttcttc acatttttct tccctttttt ccccattttt aaatagtact
     4021 ttctttgagt cataaattgt atctaaccat cttgggttct ggtcagtgct gcaggctcct
     4081 gggctcccct ctgcccagtg agcaacttat accctgcact ggatagtggc aagtacccag
     4141 cctgggactt ccctggaact gagggatgca tagctgtctg gggaagcact gacggccact
     4201 cactcaccct gtgctgctgc aagtttgaca gaaccacatc acatcgtgga gaagctggtg
     4261 caggagttcc tagagcccca gggtcaactg tcctctctag catgcagcct gtgacagctt
     4321 gcttcaggac aaagcaacag tgaagtgaga aaatgtcaac aggagagaaa gggcccggca
     4381 accctctggc cctaacctgc tctagcctgt acatcccaca tcctccgtcc gtctgtccat
     4441 ccagggtttg tctgtcctga aagtgacacc caccagctct gcgggagact cttggtagac
     4501 agacctgtgg ggtagcaggc ctggcaggag tgggacagcc ccttgaagca ttctccctca
     4561 gtattaccta ccctgtgcca ctggcctgac cctcgagaca gctcaaggat ccgtggtgtg
     4621 gccacctgcc agacccccaa ggagagaggc caagagtggc cctggcacag tgtgtctgct
     4681 agctgcttcc acacccctta gccatgttat ctgtagagta ccggatagtg tttgcttttt
     4741 cctcccaagc tgacagaagc tgggcatcag tgatctgttg tgttggatta ataggtcctt
     4801 ccccaaatgg gacctgagga aatagcaggt gtccagctga tgtgttgggc cttttctagg
     4861 aaagggacca agccccttca agtggggagg cccagagtta cctgccatat cccacatagt
     4921 ggaggcgttc ccgcagccgc caccactagc ctccttaggg ctggccttgt ccaaagaatg
     4981 ggggtgggag cgccaagggg cagagactct ccttgaccct ctccctaagg ttggatcagg
     5041 gaactgggta agacctgcag aaggtttctc tgagtcactc accaggccct acaagtccgc
     5101 tttcttgcag gctgcctctt ttatattggg tctcttggcc caactgcttc cttcttgtta
     5161 ataaggagac ctgacgcaca cagccagtgg attcccctcc acctcgggag gggacaggct
     5221 cccacatccc atcccaccct ccacacccca aagagaaatc ccttcaaaac agtttggggc
     5281 ctgtagccag ggtgggaggg gcttgtgccc cacagcctca caacccttgg ggtcagtgca
     5341 ccaagatcaa gttggttggt ttgtcttgtg ttttttattt tgttttattt tcttaaacaa
     5401 tcatcaatga gatttgtctt tgggccccag ccttggccac gaggccctga ggccaaggct
     5461 ggggccctgg tgagcatagg ataggtaggg tgagtacagt gtggcagtgt ttgggtcccg
     5521 acaccccttt gaaaaccccc tttttgtaaa agccaggctt ggtagtgggc acctgtcatc
     5581 ccagcactca ggaggcaggg tcaggaggat tacaggttca aagccagtct ggtctatatt
     5641 agaaaaagaa aactgtcctt ttgctaaaga aaaattaaat gaatttttaa ggctgaaatc
     5701 tgtgggtaag atggagtctg gagctttcct cttggaacag ttaaccgaag accctcatgg
     5761 gcaaggacat ccgcttgact ccccactcac catcaggcca cacttttaaa gaaaaattgt
     5821 tctctaacca ggattgtaac aaatgtgtaa atagtatttc tgagttgaaa gtcgatggtg
     5881 caaatatgta tataacgtac tgtattttta caatgatcgt cgcatggctc tcccaccccc
     5941 ttttgtactc agtatctgtc ttccagaaac ctcacctgcc ttctctctca tgtggtctct
     6001 taatccagta attgtattac tgccattaaa ggatgcagtt attttaaaca gaaaaaaaaa
     6061 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaa
//
