LOCUS       NM_001359875            6206 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus zinc finger CCCH type containing 13 (Zc3h13),
            transcript variant 1, mRNA.
ACCESSION   NM_001359875 XM_006519445
VERSION     NM_001359875.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6206)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 6206)
  AUTHORS   Wen,J., Lv,R., Ma,H., Shen,H., He,C., Wang,J., Jiao,F., Liu,H.,
            Yang,P., Tan,L., Lan,F., Shi,Y.G., He,C., Shi,Y. and Diao,J.
  TITLE     Zc3h13 Regulates Nuclear RNA m6A Methylation and Mouse Embryonic
            Stem Cell Self-Renewal
  JOURNAL   Mol Cell 69 (6), 1028-1038 (2018)
   PUBMED   29547716
  REMARK    GeneRIF: Zc3h13 plays a critical role in anchoring WTAP, Virilizer,
            and Hakai in the nucleus to facilitate m(6)A methylation and to
            regulate murine embryonic stem cell self-renewal.
REFERENCE   3  (bases 1 to 6206)
  AUTHORS   Knuckles,P., Lence,T., Haussmann,I.U., Jacob,D., Kreim,N.,
            Carl,S.H., Masiello,I., Hares,T., Villasenor,R., Hess,D.,
            Andrade-Navarro,M.A., Biggiogera,M., Helm,M., Soller,M., Buhler,M.
            and Roignant,J.Y.
  TITLE     Zc3h13/Flacc is required for adenosine methylation by bridging the
            mRNA-binding factor Rbm15/Spenito to the m6A machinery component
            Wtap/Fl(2)d
  JOURNAL   Genes Dev 32 (5-6), 415-429 (2018)
   PUBMED   29535189
  REMARK    GeneRIF: identified Zc3h13 (zinc finger CCCH domain-containing
            protein 13)/Flacc [Fl(2)d-associated complex component] as a novel
            interactor of m(6)A methyltransferase complex components in
            Drosophila and mice
REFERENCE   4  (bases 1 to 6206)
  AUTHORS   Yue,Y., Liu,J., Cui,X., Cao,J., Luo,G., Zhang,Z., Cheng,T., Gao,M.,
            Shu,X., Ma,H., Wang,F., Wang,X., Shen,B., Wang,Y., Feng,X., He,C.
            and Liu,J.
  TITLE     VIRMA mediates preferential m6A mRNA methylation in 3'UTR and near
            stop codon and associates with alternative polyadenylation
  JOURNAL   Cell Discov 4, 10 (2018)
   PUBMED   29507755
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 6206)
  AUTHORS   Guo,G., Huss,M., Tong,G.Q., Wang,C., Li Sun,L., Clarke,N.D. and
            Robson,P.
  TITLE     Resolution of cell fate decisions revealed by single-cell gene
            expression analysis from zygote to blastocyst
  JOURNAL   Dev Cell 18 (4), 675-685 (2010)
   PUBMED   20412781
REFERENCE   6  (bases 1 to 6206)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   7  (bases 1 to 6206)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY127373.1, BC138264.1, AW536655.1 and BC082576.1.
            
            On Jan 18, 2018 this sequence version replaced XM_006519445.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC138264.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-61                BY127373.1         2-62
            62-5626             BC138264.1         1-5565
            5627-6164           AW536655.1         1-538               c
            6165-6206           BC082576.1         3665-3706
FEATURES             Location/Qualifiers
     source          1..6206
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 39.8 cM"
     gene            1..6206
                     /gene="Zc3h13"
                     /gene_synonym="2600010B19Rik; 3110050K21Rik;
                     4930570G11Rik"
                     /note="zinc finger CCCH type containing 13"
                     /db_xref="GeneID:67302"
                     /db_xref="MGI:MGI:1914552"
     exon            1..300
                     /gene="Zc3h13"
                     /gene_synonym="2600010B19Rik; 3110050K21Rik;
                     4930570G11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            301..426
                     /gene="Zc3h13"
                     /gene_synonym="2600010B19Rik; 3110050K21Rik;
                     4930570G11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            427..536
                     /gene="Zc3h13"
                     /gene_synonym="2600010B19Rik; 3110050K21Rik;
                     4930570G11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            537..648
                     /gene="Zc3h13"
                     /gene_synonym="2600010B19Rik; 3110050K21Rik;
                     4930570G11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            649..757
                     /gene="Zc3h13"
                     /gene_synonym="2600010B19Rik; 3110050K21Rik;
                     4930570G11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            758..897
                     /gene="Zc3h13"
                     /gene_synonym="2600010B19Rik; 3110050K21Rik;
                     4930570G11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            898..1055
                     /gene="Zc3h13"
                     /gene_synonym="2600010B19Rik; 3110050K21Rik;
                     4930570G11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1056..1253
                     /gene="Zc3h13"
                     /gene_synonym="2600010B19Rik; 3110050K21Rik;
                     4930570G11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1254..1561
                     /gene="Zc3h13"
                     /gene_synonym="2600010B19Rik; 3110050K21Rik;
                     4930570G11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1562..2212
                     /gene="Zc3h13"
                     /gene_synonym="2600010B19Rik; 3110050K21Rik;
                     4930570G11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2213..2404
                     /gene="Zc3h13"
                     /gene_synonym="2600010B19Rik; 3110050K21Rik;
                     4930570G11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2405..3005
                     /gene="Zc3h13"
                     /gene_synonym="2600010B19Rik; 3110050K21Rik;
                     4930570G11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3006..3109
                     /gene="Zc3h13"
                     /gene_synonym="2600010B19Rik; 3110050K21Rik;
                     4930570G11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3110..4300
                     /gene="Zc3h13"
                     /gene_synonym="2600010B19Rik; 3110050K21Rik;
                     4930570G11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            4301..4813
                     /gene="Zc3h13"
                     /gene_synonym="2600010B19Rik; 3110050K21Rik;
                     4930570G11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            4814..4966
                     /gene="Zc3h13"
                     /gene_synonym="2600010B19Rik; 3110050K21Rik;
                     4930570G11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            4967..5167
                     /gene="Zc3h13"
                     /gene_synonym="2600010B19Rik; 3110050K21Rik;
                     4930570G11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            5168..5331
                     /gene="Zc3h13"
                     /gene_synonym="2600010B19Rik; 3110050K21Rik;
                     4930570G11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            5332..6165
                     /gene="Zc3h13"
                     /gene_synonym="2600010B19Rik; 3110050K21Rik;
                     4930570G11Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6145..6150
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zc3h13"
                     /gene_synonym="2600010B19Rik; 3110050K21Rik;
                     4930570G11Rik"
                     /note="hexamer: AATAAA"
     polyA_site      6164
                     /gene="Zc3h13"
                     /gene_synonym="2600010B19Rik; 3110050K21Rik;
                     4930570G11Rik"
                     /note="major polyA site"
ORIGIN      
        1 gtcggctttt agatgctgcc agtgtagcgg ccaggcagag ttgtggtctt agcgttgctc
       61 tgcagtggct tctgtgcgtc tctcgtctcg tgtccggagc tctccagagc tgggagaaga
      121 tccgggcggc tccgctgctc cctgttcccg gcgtccgccc cgcttgagga gggccggccc
      181 ctgggagccg cgcgtgcacg tcctcttggt cgtcctcccg gggccgggcg cggggacagc
      241 cggagctgag gcgtcaggga cgtcctgaag actgcgctta caagggtgct tggagaggag
      301 tagttcaaaa tgtcaaaaat taggagaaag gtcacagtgg aaaacaccaa gaccatatct
      361 gagagtacat cccgaagacc tagcgtattt gagaggcttg gccccagcac tggaagcaca
      421 acagagacac agtgtcgtaa ctggctgaag actggcagct gcctctatgg aaacacatgt
      481 aggttcatac atggcccttc acctcgtggg aaaggctaca gcagcaatta cagaaggtca
      541 ccagaaagac ccacaggtga cctcagagaa agaatgaaga ataagcgtca ggatgtggat
      601 tctgaatccc agaaacggaa tacagaggag ccatcctcac ctgttaggaa agaatcttca
      661 agagggagac atagagacaa ggaagacata aaaattgtta aggagagaac tccagaaagt
      721 gaagaagaaa atgtagaatg ggaaactaac agagatgatt ctgacaatgg agatattaat
      781 tatgattatg ttcatgagtt atcattggaa atgaagcggc agaaaataca gagagaattg
      841 atgaaattgg aacaagaaaa tatggataag agagaagaaa ttatcattca aaaggaggtt
      901 tccccagaag tggttagatc aaaattgtct ccatcacctt ctctgagaaa gtccagtaaa
      961 tctccaaaac gaaagtccag ccccaaggca tcttcagctg gcaagaagga gcggaaggct
     1021 gctgtggtgg cttctccgct gttggaccag cagagaaatt caaagggcaa ccaaagtaaa
     1081 aagaaagggc cgcgcactcc gagtccacct cctcctatac tagaagatat cattctgggg
     1141 aaaaagtaca aagaaaagta taaagtgaaa gacaggatag aagaaaaacc aagagatggg
     1201 aaggacagag gccgggattt tgaaaagcaa agagaaaaac gagacaagcc aaggtcttct
     1261 tctccgggac agcaccattc tcctctgtct tctagacatc actcgtcatc ctcacagtca
     1321 gggtcatcta ttcagagaca ctctccttct cctcgccgga agagaactcc ttccccatcc
     1381 taccagagga ctttaactcc atctttacga cgttctgcct ctccttatcc aacccactgt
     1441 ctgtcttctc ctcagagaaa gcaaagtcct ccaagacatc gctctccaat gcgagagaaa
     1501 gggaggcatg atcacgaacg gacttcacag tcacatgacc ggcgtcacga aaggagggaa
     1561 gaaactcgag gcaaaaggga tagagaaaag gataccagag aagagcgaga gtctgaacat
     1621 gaccacaggg atgacagaga accacgagac agccgggacc ggagagacac tagagaccgc
     1681 agggaactta gagactccag agacatgcgg gactccagag agatgaggga ttatagcaga
     1741 gatgccaagg agagccgcga tcccagagac tcccggtcag ctcgggatgt ccatgactac
     1801 agggaccgtg aagctcggga tgctcatgct cgagatgttc gagatgctag ggatgctcgg
     1861 gatgctaggg atgctcggga tattcgggat gtccgtgatg tccgggatgt ccgggatgtc
     1921 cgggatgtcc gggatgtgcg agatgtgcgt gatgtccgag atgttcgaga tgctcgcgat
     1981 gtccgggatg tccgggatgc tcgcgatgtc cgggatgtcc gggatgttcg ggatggtcat
     2041 cgaaaggagg atgtatacca ggaagaagcc cgcagttatg gcagaaacca cctgagagaa
     2101 gagagttcta gagttgaact aaggaatgac tctagaaatg agtctcgaag tgaaattaga
     2161 aacgatcgga tgggcagaag tagggggaga ggtccagaac tgcctgaaaa gggaagtcga
     2221 ggaacaagag gttcccaaat ggatagccac agtagtggca gcaactacca tgacagctgg
     2281 gaaactcgca gtagctatcc tgaaagagac agataccctg agagagacac tcgggatccg
     2341 gccagggatt cttcctttga gagaaggcat ggagaaagag accgtcggga taacagggaa
     2401 cgagatcaaa gaccaagctc acctattcgc catcagggaa ggagtgagga gcttgagcga
     2461 gatgaaagaa gagaggaacg aagaatagac agagtggatg agagacgaga cgatagggtc
     2521 agggacagag atagggatcg agagcgagaa agggagcggg agagggaacg agagcgggag
     2581 cgagaaaagg aaagagaaag agaactagaa agagagagag ctagagagcg ggaaagagag
     2641 agagagaaag agagggagag ggagcgagaa cgagagagag atcagcgaga tcgtgaccat
     2701 gatcgagagc gagaaagaga gagggagcga gagagggaaa aagaacggga gcgagagcga
     2761 gaagagagag agagggagag agaaagggaa agggaacggg agagagagag ggaacgggag
     2821 cgggagagag agcgagaacg ggagcgggag cgagagaggg ccagagaaag agaaaaagaa
     2881 cgagaacggc aaagagagtg ggaagataaa gacaagggac gcgatgaccg gagggagaag
     2941 cgcgaggata ttcatgttcg agaggacagg atccccagag acagccacga ggagaggaag
     3001 tccaagaaac gctatagaaa tgaagggagt cccagccccc ggcagtcccc caagcgccgg
     3061 cgggagcatt ctcctgacag tgacacctac cacagtgggg atgacaaaaa tgaaaaacat
     3121 agactcttga gccaggttgt acggccacag gaatctcgtt ctctcagccc atcccacctc
     3181 acagaagata ggcaaggtag atggaaagaa gaggatcgta aatcagaaag aaaggagagt
     3241 tccaggcgct acgaagagca agaactcaaa gagaagcttt cttgtggcga caggcaaagg
     3301 gagcaggccg aaagcgtgga cagctcgaga gtgcgcgccc aagacctcct cagccatcgc
     3361 caggctgaag accgcgaccg tgacgggtct gatcgagccc atgatgaaaa gaaaaaagca
     3421 aaagctccga agaaacctgt aaagaaaaag aaggaggagg atgttggagt agagaggggc
     3481 aaccttgaga cacatgagga tagtcaggta ttttcaccaa aaaaaggaca gaagaagaaa
     3541 aacattgaaa aaaagcgtaa aagatccaag ggtgattctg atgtttctga tgaggaggca
     3601 gccccgcaga ataagaagaa gagagggcct cgcacacccc ctctggccat caaggaggag
     3661 ctggctgaca tctccactga caaggatggc gtcctggagg atccactgaa gaaagaaaat
     3721 acagccttta gtgactggtc tgatgaggat gtgcctgacc gcacagaggg gctggaagcc
     3781 gagcacaccg cagccactgc cactcctggt agcacccctt cccccctgtc ttctcttctc
     3841 cctcctccac cccctgtggc tgctgccagt actgcagcca ctgctcttgc ctcctcagct
     3901 gtttctgcta ccacctctgc cacctcttca agctctgctg ccacctccaa taccaatggc
     3961 agtgaagact cacatagaaa gtgccacagg gcacgagggg agaaggtaga ggtgtcccat
     4021 gtgaccctag aagacacacc acatcgcaag ctggtggatc aaaaaagaag cagcagcctc
     4081 ggaagcaatc gaagtcaccg cagccacacc tctggtcgcc tacgctcccc atctaatgat
     4141 tctgctcatc gaagtgggga tgaccagggt agtcggaaga gagtgctcca tagtggctcc
     4201 agggatagag agaaaacaaa aagcctagaa atcacaggag aaagaaaatc taggattgat
     4261 cagttaaagc gtggagaacc cagtcgaagt acttcttcag atcgccagga ttccagaagc
     4321 catagctcaa gaagaagctc tcctgagtcg gatcggcagg ttcactcaag gtccgggtcg
     4381 tttgacagta gagaccgact tcaagaacga gataggtatg agcatgacag agagcgggag
     4441 agggaccgga gagatcccag acagcgggaa tgggatcgtg aagcggagaa agagtggcct
     4501 cggaccagag accgagacag gcttcgggaa cgagacagag accgggacag aaggagagac
     4561 ttggacagag aaagagagag actgatctct gaccccatgg aaagggacag agaacgagag
     4621 agaacttttg agacatctca gctggaatct gggaaacgaa gcgaagtcaa attagagagt
     4681 gaacatgaga gagatctgga aggcagctcc cgggactccg tggccttgga caaagaaagg
     4741 atggacagag acctgggctc tgtgcaggga tttgaagatg tgagtaaagc tgagagaaca
     4801 gagagtcttg aagcaggaga tgatgaatcc aagttagatg atgcacattc attaggatct
     4861 ggtgctgggg aaggatatga gcccatcagt gatgacgagc tagatgaaat tctggcaggg
     4921 gatgcagaaa agagagagga ccagcaggaa gaagagaaga tgccagatcc attagatgta
     4981 atagatgtgg actggtctgg actaatgcca aagcacccga aagaaccgag agagcctggg
     5041 gctgcactct taaagttcac gcctggagct gttctgctac gagttgggat ttctaaaaag
     5101 ttggctggtt ctgagctctt taccaaagtt aaagaaacat gtcaacaact tgtagaaaaa
     5161 cccaaagatg cagacagcct tttcgaacat gaactagggg ctctcaacat ggctgcttta
     5221 cttcgaaaag aagagcgagc aagtcttctt agtgacctgg gaccatgttg taaagcatta
     5281 tgtttcagac gggactctgc aatccggaag cagcttgtga agaacgaaaa gggaactgtg
     5341 aagcaggcgt acacaaacac tccgatggta gacaatgagc tgcttcggct aagtcttcgg
     5401 ttatttaaga agaaggccac ctgccatgcc cctggacagg aaaagactga agatggcaaa
     5461 ttaggaccgt gcagtatcca gcaggagctg tgtgtgtcct aggcgaagat tgaggatggc
     5521 ccctttgctc catcttccca gtagtgcata atctttcttg acgttctttg gtttgaagac
     5581 attgctaact acagaggcag aggagtcacc agccacatca gcagtgaaaa cttcaatctt
     5641 cagagacacg tgctttggtt catttaagat tttccattaa ttttatacag taattgacac
     5701 tcaggcaaaa taatgtgaaa atgtctagat ttagtaattt cgtctgtgtc ttcattaaaa
     5761 ttgaagattt taagaaacca ggtcacccct gctcttccag cctatgaata cttcttatga
     5821 aataaaagca ctgattttca ctctggatca ccatgcagaa actgacctta gtcagaaagg
     5881 agtgttgcca gaagctgctg cacaggctgc agggccgtgt acagagctct gaggagcgcc
     5941 agcctagtaa gcatgctggg aggccgtctc cactacagga agcccaggtg gtttggtttt
     6001 tttcttttga aatttctaaa ataaatgact ccatgggatt ttttttttac acgtgtacat
     6061 tactacatta tatattggaa gtctttggac ctttgagtgg ggtttaattg ttcattatca
     6121 gagactgtgt gctattttat ttttaataaa tgtatgttcc cttttaaaaa aaaaaaaaaa
     6181 aaaaaaaaaa aaaaaaaaaa aaaaaa
//
