LOCUS       NM_001368810            8563 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus zinc finger CCCH type containing 12C (Zc3h12c),
            transcript variant 2, mRNA.
ACCESSION   NM_001368810 XM_006510334
VERSION     NM_001368810.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 8563)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 8563)
  AUTHORS   Wawro,M., Kochan,J., Sowinska,W., Solecka,A., Wawro,K., Morytko,A.,
            Kwiecinska,P., Grygier,B., Kwitniewski,M., Fu,M., Cichy,J. and
            Kasza,A.
  TITLE     Molecular Mechanisms of ZC3H12C/Reg-3 Biological Activity and Its
            Involvement in Psoriasis Pathology
  JOURNAL   Int J Mol Sci 22 (14), 7311 (2021)
   PUBMED   34298932
  REMARK    GeneRIF: Molecular Mechanisms of ZC3H12C/Reg-3 Biological Activity
            and Its Involvement in Psoriasis Pathology.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 8563)
  AUTHORS   Liu,B., Huang,J., Ashraf,A., Rahaman,O., Lou,J., Wang,L., Cai,P.,
            Wen,J., Anwaar,S., Liu,X., Ni,H., Ganguly,D., Zhao,J. and Yang,C.Y.
  TITLE     The RNase MCPIP3 promotes skin inflammation by orchestrating
            myeloid cytokine response
  JOURNAL   Nat Commun 12 (1), 4105 (2021)
   PUBMED   34215755
  REMARK    GeneRIF: The RNase MCPIP3 promotes skin inflammation by
            orchestrating myeloid cytokine response.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 8563)
  AUTHORS   Garg,A., Roske,Y., Yamada,S., Uehata,T., Takeuchi,O. and
            Heinemann,U.
  TITLE     PIN and CCCH Zn-finger domains coordinate RNA targeting in ZC3H12
            family endoribonucleases
  JOURNAL   Nucleic Acids Res 49 (9), 5369-5381 (2021)
   PUBMED   33950203
  REMARK    GeneRIF: PIN and CCCH Zn-finger domains coordinate RNA targeting in
            ZC3H12 family endoribonucleases.
REFERENCE   5  (bases 1 to 8563)
  AUTHORS   Guo,G., Fu,R., Zhang,L., Chao,T., Jiang,Z., Dong,L., Huang,R.,
            Lu,L., Yang,W., Gu,Y., Liang,Y. and Zheng,Q.
  TITLE     Gfi1 and Zc3h12c orchestrate a negative feedback loop that inhibits
            NF-kB activation during inflammation in macrophages
  JOURNAL   Mol Immunol 128, 219-226 (2020)
   PUBMED   33157351
  REMARK    GeneRIF: Gfi1 and Zc3h12c orchestrate a negative feedback loop that
            inhibits NF-kB activation during inflammation in macrophages.
REFERENCE   6  (bases 1 to 8563)
  AUTHORS   von Gamm,M., Schaub,A., Jones,A.N., Wolf,C., Behrens,G., Lichti,J.,
            Essig,K., Macht,A., Pircher,J., Ehrlich,A., Davari,K., Chauhan,D.,
            Busch,B., Wurst,W., Feederle,R., Feuchtinger,A., Tschop,M.H.,
            Friedel,C.C., Hauck,S.M., Sattler,M., Geerlof,A., Hornung,V.,
            Heissmeyer,V., Schulz,C., Heikenwalder,M. and Glasmacher,E.
  TITLE     Immune homeostasis and regulation of the interferon pathway require
            myeloid-derived Regnase-3
  JOURNAL   J Exp Med 216 (7), 1700-1723 (2019)
   PUBMED   31126966
  REMARK    GeneRIF: required for immune homeostasis and regulation of the
            interferon pathway
REFERENCE   7  (bases 1 to 8563)
  AUTHORS   Liang,J., Wang,J., Azfer,A., Song,W., Tromp,G., Kolattukudy,P.E.
            and Fu,M.
  TITLE     A novel CCCH-zinc finger protein family regulates proinflammatory
            activation of macrophages
  JOURNAL   J Biol Chem 283 (10), 6337-6346 (2008)
   PUBMED   18178554
  REMARK    GeneRIF: MCPIP1, 2, 3, and 4, encoded by four genes, Zc3h12a,
            Zc3h12b, Zc3h12c, and Zc3h12d, respectively, regulates macrophage
            activation.
REFERENCE   8  (bases 1 to 8563)
  AUTHORS   Lau,N.C., Seto,A.G., Kim,J., Kuramochi-Miyagawa,S., Nakano,T.,
            Bartel,D.P. and Kingston,R.E.
  TITLE     Characterization of the piRNA complex from rat testes
  JOURNAL   Science 313 (5785), 363-367 (2006)
   PUBMED   16778019
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CT009732.8.
            
            On Feb 28, 2019 this sequence version replaced XM_006510334.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR9219380.15403.1,
                                           SRR7345562.183504.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164138, SAMN01164139
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-95                CT009732.8         143820-143914
            96-847              CT009732.8         148757-149508
            848-987             CT009732.8         166481-166620
            988-1222            CT009732.8         172792-173026
            1223-1329           CT009732.8         175538-175644
            1330-8563           CT009732.8         176381-183614
FEATURES             Location/Qualifiers
     source          1..8563
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 28.62 cM"
     gene            1..8563
                     /gene="Zc3h12c"
                     /gene_synonym="A230108E06; C230027N18Rik; mKIAA1726"
                     /note="zinc finger CCCH type containing 12C"
                     /db_xref="GeneID:244871"
                     /db_xref="MGI:MGI:3026959"
     exon            1..95
                     /gene="Zc3h12c"
                     /gene_synonym="A230108E06; C230027N18Rik; mKIAA1726"
                     /inference="alignment:Splign:2.1.0"
     CDS             72..2726
                     /gene="Zc3h12c"
                     /gene_synonym="A230108E06; C230027N18Rik; mKIAA1726"
                     /note="isoform 2 is encoded by transcript variant 2;
                     probable ribonuclease ZC3H12C; zinc finger CCCH
                     domain-containing protein 12C; regnase-3"
                     /codon_start=1
                     /product="probable ribonuclease ZC3H12C isoform 2"
                     /protein_id="NP_001355739.1"
                     /db_xref="GeneID:244871"
                     /db_xref="MGI:MGI:3026959"
                     /translation="MSLYFPANEYGVLCIQEYRKSSKVESSARNSFMGLKDHLGHDLG
                     HLYMESTDPQMSAAVPWPMVEKPTMDTVNSGKEGKGVSEENVSSGDSEGSTSSDHESE
                     QLSSLSVEPCSLTKTHRQLCRSPCLEPRLLKHSDILQDFKPEESQTPSKEVKKPPDVV
                     REYQTKLEFALKLGYSEEQVQLVLNKLGTDALINDILGELVKLGNKSEADQTVSTINS
                     VMRETSSLESQRSESPMQEVVVDDGENLRPVVIDGSNVAMSHGNKEVFSCRGIKLAVD
                     WFLERGHKDITVFVPAWRKEQSRPDALITDQEILRKLEKEKILVFTPSRRVQGRRVVC
                     YDDRFIVKLAFESDGIIVSNDNYRDLANEKPEWKKFIDERLLMYSFVNDKFMPPDDPL
                     GRHGPSLDNFLRKKPIVPEHKKQPCPYGKKCTYGHKCKYYHPERGSQPQRSVADELRA
                     MSRNTAAKTTNEGGLVKSNSVPCSTKADSTSDVKRGAPKRQSDPSIRTHVYQDIEEKL
                     PTKNKLETRSVPSLVSIPATSTAKPQSTTPLSNGLPSGVHFPPQDQRPQGQYPPMMMA
                     TKNHGTPMPYEQYPKCDSPVDVGYYSMLNAYSNLSISGPRSPERRFSLDTDYRVNSVA
                     SDCSSEGSMSCGSSDSYVGYNDRSYVSSPDPQLEESLKCQHMHPHSRLNSQPFLQNFH
                     DPLTRVQSYSHEEPKFHPKRPLPHLAMHLQHPAVGARSSCPGDYPSPPSSAHSKAPHL
                     GRSLVATRIDSISDSRLYDSSPSRQRKPYSRQEGLGSWGRPSYGLEAYGYRQTYSLPD
                     NSTPPCYESITFQSLPEQQEPTWRIPYCGMPHDPPRYQDNREKIFINLCNIFPPDLVR
                     LVMKRNPHMTDAQQLAAAILVEKSQLGY"
     exon            96..847
                     /gene="Zc3h12c"
                     /gene_synonym="A230108E06; C230027N18Rik; mKIAA1726"
                     /inference="alignment:Splign:2.1.0"
     exon            848..987
                     /gene="Zc3h12c"
                     /gene_synonym="A230108E06; C230027N18Rik; mKIAA1726"
                     /inference="alignment:Splign:2.1.0"
     exon            988..1222
                     /gene="Zc3h12c"
                     /gene_synonym="A230108E06; C230027N18Rik; mKIAA1726"
                     /inference="alignment:Splign:2.1.0"
     exon            1223..1329
                     /gene="Zc3h12c"
                     /gene_synonym="A230108E06; C230027N18Rik; mKIAA1726"
                     /inference="alignment:Splign:2.1.0"
     exon            1330..8563
                     /gene="Zc3h12c"
                     /gene_synonym="A230108E06; C230027N18Rik; mKIAA1726"
                     /inference="alignment:Splign:2.1.0"
     regulatory      8532..8537
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zc3h12c"
                     /gene_synonym="A230108E06; C230027N18Rik; mKIAA1726"
                     /note="hexamer: ATTAAA"
     polyA_site      8563
                     /gene="Zc3h12c"
                     /gene_synonym="A230108E06; C230027N18Rik; mKIAA1726"
                     /note="major polyA site"
ORIGIN      
        1 attgttcttc ttgcctgcct ggaagtctgc agctaaaatt gttgttactg ctggagctgc
       61 cacagaaacc aatgtctttg tattttcctg ctaacgaata cggggtgctt tgcattcaag
      121 aatacaggaa aagcagcaaa gtggagtcaa gtgcacggaa cagcttcatg ggcctgaagg
      181 atcacctggg gcatgatctt ggccatcttt atatggagag cactgaccca cagatgagtg
      241 cagctgtgcc ttggcctatg gtagagaaac caacaatgga tacagtcaat tcggggaagg
      301 aaggaaaagg ggtgtcagaa gagaatgtga gctccggcga ctctgaggga agcacgagtt
      361 ctgatcatga gtcagaacaa ctgagtagcc tttcggtaga gccatgctca ttaaccaaga
      421 ctcacagaca gctatgtcgc tctccctgct tagagcctcg cctactgaaa cacagtgaca
      481 ttttgcaaga ctttaaacca gaagagtccc agactccatc taaggaagtg aagaaacccc
      541 ctgatgtggt tcgagaatac caaacaaaac tggagtttgc acttaagtta ggttattctg
      601 aagaacaggt ccagcttgtg ctaaacaaac ttggtactga tgctttaatc aatgatatat
      661 tgggagaact tgtcaaactt ggaaataaaa gtgaagccga tcaaacagtt agtactatta
      721 acagcgtaat gcgagaaacc tcatccctgg agtctcagag gtctgaatct ccaatgcaag
      781 aggttgtagt agatgacggt gagaatctga gaccagtagt tattgatggc agcaatgtgg
      841 caatgagcca tggaaacaaa gaagtattct cgtgccgagg aataaaattg gcggtggatt
      901 ggtttttgga aagaggccat aaagatatca cggtctttgt tcctgcttgg agaaaagaac
      961 agtcccgccc tgacgccctc atcacagatc aggaaatttt acgtaaacta gagaaggaaa
     1021 aaatcctggt attcacacca tcacggcgtg tccagggcag gcgagtggtg tgctatgatg
     1081 acagattcat cgtgaagctg gcttttgagt ccgatggtat aattgtgtcc aatgataact
     1141 acagagattt ggcaaatgag aaaccagaat ggaagaagtt catagatgag cggttattga
     1201 tgtattcctt tgtcaatgac aagttcatgc ccccagatga ccctcttggc agacatggcc
     1261 caagtctgga taattttctg aggaagaaac ccattgttcc tgagcacaaa aagcagcctt
     1321 gtccctatgg aaagaagtgt acgtatggac acaagtgcaa atactaccac ccagaaaggg
     1381 gcagtcagcc tcagcggtca gtggctgatg aacttcgtgc catgtctaga aacacagcag
     1441 ccaaaactac aaatgaaggg ggactggtga aaagcaacag tgttccttgc agcaccaagg
     1501 cagacagcac ttcggatgtt aaacgcggtg ctccaaagag gcagtcagac ccaagcataa
     1561 ggactcacgt ctaccaagac atagaggaga agcttcccac caaaaacaag ttggaaacca
     1621 ggtctgtacc ttccttagtt agtatcccgg ccacttctac tgcaaaaccc caaagcacta
     1681 cacctttaag caatggcctt ccatctggag ttcatttccc acctcaggat caaagaccac
     1741 agggacaata ccctccaatg atgatggcaa ccaaaaatca tggaacgcca atgccttatg
     1801 aacagtatcc aaaatgtgac tcccctgttg acgttggata ttattccatg ttgaatgcat
     1861 attctaatct gagtatctca ggcccccgaa gtcctgaaag gcgtttctca ctagacactg
     1921 attacagagt aaactctgtg gcttcagact gcagcagtga agggagcatg agttgtggga
     1981 gcagcgactc ctacgtgggg tacaatgacc gctcctatgt cagctctcct gacccacagc
     2041 tggaagagag tctcaagtgt cagcacatgc acccccacag ccgccttaat tcccagccct
     2101 tcctgcagaa tttccacgat cccttaacca gagtccagag ttacagtcac gaagaaccaa
     2161 agttccatcc caagcgtcct cttccacact tggctatgca tctgcagcac cctgccgtgg
     2221 gtgcccgctc cagctgtcct ggcgattacc cctccccacc aagttcagca cattcgaagg
     2281 caccacacct agggaggtcc ttagtggcca cgagaataga cagcatttct gattcccgac
     2341 tctatgatag ttctccttca agacaaagaa agccttattc tcgccaggaa ggcctaggaa
     2401 gctggggtag gccaagctat gggctggaag catatggcta tcggcagacg tactccttac
     2461 ccgataattc cacgccccca tgctatgagt cgatcacctt ccagagcctg cctgagcagc
     2521 aggaacccac ctggagaatc ccctactgtg gaatgccaca cgatcctcca aggtaccagg
     2581 acaaccgaga gaagattttt atcaatttgt gtaacatctt cccccctgac cttgtgaggc
     2641 tcgtcatgaa aaggaatcct catatgacgg atgcccagca gctcgccgca gccatcttag
     2701 tggagaaatc gcagctgggt tactgaaagc atgatgcatc tttgtggtgt tgagtagttt
     2761 tttgttcagc tcagttgctg agggaggttt gctacaatag cacatgtgat ctccttctcg
     2821 gcagggaggt tatatagtat ccatttatgt gaaatactgt atcatggaat tgtatggaac
     2881 cccacttggt ggacttatca cgggattgct ttacattcaa actttttttt ttttttttta
     2941 acatttcctt tttaaagcta tatacacttg gctggaaatt tctccagttt gatttactag
     3001 atgtatctgt gatctttgat attcctcttt ggtgcatcag gggtttatat gcagcacttt
     3061 ttatccttgt ttcctgtctt attaacttgg tgtttgtctg tcaactgcaa gcaattgcag
     3121 caccttcaga atgtggaggt accgggctag acctagcaaa caatgtcctc aagccaagcg
     3181 tagctagaat cctttacagc tttttaagtt atttttattt ggggaaagtg ggcttctttg
     3241 tgctataatc attatttata ggaacaaaga tatactacag cactgacttt atatttttaa
     3301 aaaatttaag cttccagtta tgttaaaatg gaaatagtac atattagagt gattcccggt
     3361 atggcacttt ttattatttt atttttgttt ggatgtttcc tgttaagaaa attagttatt
     3421 ttaaatggtc agtttaaaag aaagcagatg caatcaatcg aaaaaaaatg tttctttttt
     3481 atgaataagg caaaagctgt gactattaca ggttagggct ttgctttcta gctaaaatgt
     3541 gctttttgac agtagaagtg ggattgaagt ccttgatttc cattaacatg tatttttaat
     3601 ctgtcttttt gtgggaggca cagtactgga tgaatagccc tttctcagta cttgcctgtt
     3661 tttaatgaat ccaagtattc tcaatgcaac ttttatattg aatacactct agcttcctgc
     3721 tatttactga ggctggcctg aggtggtctg atgtgttgag gatatgcaac atttactgat
     3781 actgcactag agaaatggca atggaggact tgtaaatggt aacttaaagt ttttgtaaga
     3841 tattgtatat tttccatttt cctgaaggta gtttttttgg ggagcctgct ataatattaa
     3901 ggccagactc ttgccacaaa tagtgtagtt ttagatacag actaaagtct gttctagtat
     3961 tagtaaggga tatttctggt tgcaacgtca tggcttttgc ttgctgtagc gacctttctg
     4021 agcatcagag atggatctat ggcagacagt gcagacagtg ctgtgatgga cagaggctgc
     4081 ctctgacgtt acttgttgca gcgacaagtc tagctctgct cctgtagtca gcctggaggc
     4141 ttggtctaga tgctcctgca gtctgagaga ggcaaagccc tggaaaccag aaagtacctt
     4201 ttactgttga tacaaattgt atctttttaa caataagaac tattttgatt tgtagatcta
     4261 gttaaaaaca caaatgtgta actataatta gacttttggg caacatttta tcccttattt
     4321 aaataaaaaa aatttttaaa ggaaaattga agtctagaat aggatagaaa ataaaagtaa
     4381 caattaaggt aaataaaggt gtctgtctta gttttatata ttaaaatata ttaaataaat
     4441 ttattggcat tttctttttc ctaaaactta cctagtgtga acttaactta aaataaaggt
     4501 aaaatgctgc ctgaaaataa tgtccaagca tcttcgacta ggataacatt ttcactactt
     4561 gtgtgacact gtgtgttgca tggagtagga tttgggtaca cagtaaatgc ttctaaacgg
     4621 cattgtgcat attagcatat ccaataatct gaaccatgtt cagcaaactt aattcaggaa
     4681 agtgatgttc tacagttact gctgttgtgt ttgagtgagc gtggcacaca tctgttcccg
     4741 gagtgctgca ggtggtgcca ccccagccct cccgagtgct gtgtctgaga gtgacacagc
     4801 cgacctgtga aactgtcctt gattctctca gtcataatct aaaggacaag ttgaaatgtg
     4861 gaggctaagt gaatgccaag aacagggttg caaatgtggg gttcctcata cccaggctgc
     4921 ccagccacat tgtgaggcca ggctaggaag tcagttaatg aacatgtcac ttttgcttca
     4981 tattagcact gtgattgttt ggaaatgggc acacttgact aaaatggttt aagcgagacc
     5041 ttaggtaaaa aggatatgac ttaaaatttg gccttcttac atttttagct gaagttgccc
     5101 tctttttcat ctctgccagt gtgtgtcatg gagtgggtag ctctgaccca cccactccta
     5161 catttctcag tgccattggc tgtgtgctaa gaaaaggttt tcttatgaca agaggacagt
     5221 ctgtctgtcc cctttgataa agcaccaatg ctgctttcag acgttaagaa taaggtgatt
     5281 ggcaaatttt agctacatca gtttctcaaa aaacaaaaca aaacaaaaac ctcaggtaat
     5341 aagtaaaagg agtccattat caaatttgta gctgatcata aaccttaatt ttagctagaa
     5401 tatttcttcc caatctctaa tttctattta agagactagc taaaataaat aaataacctg
     5461 aaatggtgtg ctaatgaata gtaaaagtca gaattggtca gctgattaaa aaggactcag
     5521 actggaatat tctgcccctg aataatagac agtcaactgt actttatgca gtaatagcag
     5581 tttgttgtcc ctgtgtctta gtccagaggg aatagtacct aactggccaa aatggccctc
     5641 agaatttcct cttttcttgc atgtaatata gacatttctt gttatcctaa tgggagtttg
     5701 tcactgacct aaacagtgaa agtaatggtc gccagtaaaa tatttgacac tggtgacaac
     5761 ttgaattttt gatttcatga aaatacattt atgaaaatat gtaattacct aaagagggtg
     5821 ttttatatat acacgtttgt tatgaagtat taaaaaatag ggggttgtct ttcaatggat
     5881 aacattttcc tgattgaacg gtgtctttga gttgtgaatg accaagtcta gggtctattt
     5941 gaccaatgat aagattcaga acctcttaca tggaaagaaa cacttggttt tattcttggt
     6001 atttttaaag attattttga taattttaat agaatgtgta atttttaaat acacaaaagt
     6061 agtattgatt atacaaatga ttatttaaca tgtcttttat ggatgtatct atatgtatat
     6121 agacagtaat atatttataa aacaatatac tttatgttgt attttttagt ttgtaatgaa
     6181 tgtaagtatg actgtgtgta tgtgagcaag cactcacatg tgtgtacatg tgcacacacg
     6241 tgttgatgtg tctgtctgcc tgtgtttgaa tgctgaaacc tctttccctg acttgctggg
     6301 atttactcta aaatgtattt gggttttgct ccttttaata cccttattcc ttattcaaga
     6361 taaaataaga ggtacagttt tcttgtctgt ctgttgccag atggctcttc cattgtatta
     6421 atctctaatt cttagagaag gcctgacatc aagcagatta tgactggaga taatgactat
     6481 gttccaaata tattaaaagt gaaccccgct gtgatgtgaa aatttcagga tccacaccaa
     6541 tgaacagaat aagcctagaa gatcgagtca tccacacacc agagttcgag gaggcctggg
     6601 acctgtgaca aggaagacac gtgtgttcta gatgctctct ctataggatc tggtagtcaa
     6661 taattcaggc ttctctgaga atcagatagt ctctttactg tacacctttg cctttacagt
     6721 gtgacagcca caggtagcat agagatgaaa atgtgacctt ttaaataaaa ttttatttac
     6781 agaaacaagc aacaggccag tttttacctg tgggccattc cccagccctg tccttgaggg
     6841 aaaaaaagcc agacatctta agctgtaaat tcttgtgcat gttaatataa tcaacaatag
     6901 ctgtatctca gcagccatct agaggcagta tgacgagtca ctggtgtcct tcagaagatg
     6961 gctgtgcaac agtcacaggg aagcatttgt tacgttcagc acatccatca tttgagatgt
     7021 cacttatcta gccaccaaga aatctataaa agaaaggtat caggactggg aattttgctt
     7081 aagttcttat ttttaagtag gactccttta tcttttgttt ctcagtggcc tcgtgggcca
     7141 aaaaccagcc tttttttttt tttaactcag ccacatgttt ttcaagattg catttgtcag
     7201 ttacgttttt ctgttaggtt tttgtcttct gatgcttaac agacttaccc ttctttacaa
     7261 gtgagtttaa agattaacat actataactt cacagtgtca gatttctctg tgatgtttaa
     7321 agctgactag accaatgagt gtatttttta cattgtcact cttaataaga aacatgcgtc
     7381 ttctttctct gtctgaatgt tcactatgga gtgtttagct accttagggc ctgccatggg
     7441 agtgatgctc tcatgagcac ctgcgagtct gaattgattg aaggtacaca ccactgaaca
     7501 tgctcattca cactgctcca ttcatggtat ctcagcaata acactatctt tacaggattg
     7561 ttaaatagct acgaaaacta ccgcctactt aagtagttac accttctttt aaaattggag
     7621 tgcagtcctg gctttatcag tattgatgtt ttgtctgtta caccctctca cctcctgcct
     7681 gtcacccatg ttatgtcaac actgtcatat ttatacatgg cttttcccct aggatcctca
     7741 atccttcaga cctaaacaca atttcaggtt ttgaccattt gacagtagaa aatgtctatg
     7801 catgttttca atccttacaa acctgtgaag ttttatttct taatccatgt actgaacttt
     7861 ctgtccaggt gaacaagatg cttcccagaa aagcttttcc cacttctatc taaagcagct
     7921 catgtcttta agacaaagaa gtgcgcggtt gttttgtaag gtataaacac atacatgggt
     7981 gtatgtatgt atgtatgtat gtatatattt cctctggggt ttttttaatt ataaattttc
     8041 aaccttctgt gaaatactca caaatggtca aatactgcag acagggtata ccctcgctgt
     8101 caggtcttct attcctccca actgtagctt tttgccagta gagaatttcc ttactcatcc
     8161 ttcaagcttt tcttacagga aaaataaagt aatgaatatg tttagatcaa ccattttata
     8221 aacatattat tctgtttatc actatctgtt ctgtatgttt ctgtatagaa cttttacaat
     8281 tcccaaaaca gtggaaatag ctatatgatt ctgccataga gggggagatt ctaagatatc
     8341 catctttctt gtggcaggtg gttgttacat gaaaaaatag atctcatatg atggcataga
     8401 ttctaaataa acaaagcatt tccttttctg ttcccctggc tttctcagat tctgtgatta
     8461 gtgacattgg gctacacatg ttcagcattg atgtaaatgt tagagccaca attaattcct
     8521 attaaactga aattaaatgt caaaaattag tcatgactca aaa
//
