LOCUS       NM_001034907            6483 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus zinc finger CCCH-type containing 12B (Zc3h12b), mRNA.
ACCESSION   NM_001034907 XM_141968
VERSION     NM_001034907.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6483)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 6483)
  AUTHORS   Liang,J., Wang,J., Azfer,A., Song,W., Tromp,G., Kolattukudy,P.E.
            and Fu,M.
  TITLE     A novel CCCH-zinc finger protein family regulates proinflammatory
            activation of macrophages
  JOURNAL   J Biol Chem 283 (10), 6337-6346 (2008)
   PUBMED   18178554
  REMARK    GeneRIF: MCPIP1, 2, 3, and 4, encoded by four genes, Zc3h12a,
            Zc3h12b, Zc3h12c, and Zc3h12d, respectively, regulates macrophage
            activation.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK134628.1, AL732438.17 and BX005184.8.
            
            On Jul 28, 2018 this sequence version replaced NM_001034907.2.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7345562.1969430.1,
                                           SRR9219380.83760.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164132
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1258              AK134628.1         2-1259
            1259-1417           AL732438.17        141241-141399
            1418-1837           AK134628.1         1419-1838
            1838-1944           BX005184.8         11174-11280
            1945-6483           BX005184.8         12460-16998
FEATURES             Location/Qualifiers
     source          1..6483
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 42.14 cM"
     gene            1..6483
                     /gene="Zc3h12b"
                     /gene_synonym="A130028J20Rik; CXorf32; Gm373"
                     /note="zinc finger CCCH-type containing 12B"
                     /db_xref="GeneID:547176"
                     /db_xref="MGI:MGI:2442133"
     exon            1..469
                     /gene="Zc3h12b"
                     /gene_synonym="A130028J20Rik; CXorf32; Gm373"
                     /inference="alignment:Splign:2.1.0"
     exon            470..536
                     /gene="Zc3h12b"
                     /gene_synonym="A130028J20Rik; CXorf32; Gm373"
                     /inference="alignment:Splign:2.1.0"
     exon            537..611
                     /gene="Zc3h12b"
                     /gene_synonym="A130028J20Rik; CXorf32; Gm373"
                     /inference="alignment:Splign:2.1.0"
     exon            612..701
                     /gene="Zc3h12b"
                     /gene_synonym="A130028J20Rik; CXorf32; Gm373"
                     /inference="alignment:Splign:2.1.0"
     exon            702..1462
                     /gene="Zc3h12b"
                     /gene_synonym="A130028J20Rik; CXorf32; Gm373"
                     /inference="alignment:Splign:2.1.0"
     CDS             858..3365
                     /gene="Zc3h12b"
                     /gene_synonym="A130028J20Rik; CXorf32; Gm373"
                     /codon_start=1
                     /product="probable ribonuclease ZC3H12B"
                     /protein_id="NP_001030079.2"
                     /db_xref="CCDS:CCDS41069.1"
                     /db_xref="GeneID:547176"
                     /db_xref="MGI:MGI:2442133"
                     /translation="MTATAAVETPKMEKSASKEEKQQPKQEDSTDRGNADPEEWANSE
                     SDPEQMSCKSGHTSYQATDIQLKKKEMPSKPHRPLCRSPCLDRPSFSQSSILQDGKLD
                     LEKEYQAKMDFALKLGYAEEQIQSVLNKLGPESLINDVLAELVRLGNKGDSEAQVNLS
                     LLLPRGASSREIASPELSLEDEIDNSDNLRPIVIDGSNVAMSHGNKEEFSCRGIQLAV
                     DWFLDKGHKDITVFVPAWRKEQSRPDAPITDQDILRKLEKEKILVFTPSRRVQGRRVV
                     CYDDRFIVKLAFDSDGIIVSNDNYRDLQVEKPEWKKFIEERLLMYSFVNDKFMPPDDP
                     LGRHGPSLENFLRKRPVVPEHKKQPCPYGKKCTYGHKCKYYHPERANQPQRSVADELR
                     ISAKLSTVKIMSEDTLAKCGAGMSTAKGEITSEIKRVASKRQSDPSIRSVAVEPEEWL
                     SIARKPEASSVPSLVTALSVPTIPPPKSHAVGALNTRSASSPVPGSSHFPHQKASLEH
                     MVSMQYPPILVTNSHGTPINYTEQYPKFETMGDHDYYSVLSDFSKLSINNMHNHEYYM
                     AEANQGVYVRNPGLCTDSHMSHTRNDNYSSYNNLYLAVADAHPEGTLKLHRSASHNHL
                     QPFSHGYHEALARVQSYGSEDSKQAPHKQSVPHLAVHTQNPATGAHSSCPGDYTMPPS
                     IHPVGPSQPGRALVMTRMDSISDSRLYDSNPMRQRRPPLCREQHASWDPLPCTADSYG
                     YHSYPLGNSLMQPCYEPVMVRSMPEKMEQLWRNPWVGMCNDSREHMIPEHQYQTYKNL
                     CNIFPSNIVLAVMEKNPHTADAQQLAALIVAKLRAAR"
     exon            1463..1602
                     /gene="Zc3h12b"
                     /gene_synonym="A130028J20Rik; CXorf32; Gm373"
                     /inference="alignment:Splign:2.1.0"
     exon            1603..1837
                     /gene="Zc3h12b"
                     /gene_synonym="A130028J20Rik; CXorf32; Gm373"
                     /inference="alignment:Splign:2.1.0"
     exon            1838..1944
                     /gene="Zc3h12b"
                     /gene_synonym="A130028J20Rik; CXorf32; Gm373"
                     /inference="alignment:Splign:2.1.0"
     exon            1945..6483
                     /gene="Zc3h12b"
                     /gene_synonym="A130028J20Rik; CXorf32; Gm373"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aactgcgccg gggctgtgtg tgtaggcagc agcgccagag gaagaggagc acgaggatgc
       61 agctgcgacc gcggccccaa gagggagcag ccactgttct gtggtcgcgg ggccaaagca
      121 attggaatta agcctggggg gtcctgttgc tgagaggacc ggggcagacg gtcctgccag
      181 aagcgcaggc ctagtattcc gggagagttc ggtctgctgg gcgaaggcct gccgcctttg
      241 cttcctcctg gccctccaag tcgatggtgg tgaagttggt ggccgccagg ggcacaagcg
      301 ccaggctggt tctcttgcac ccggcgctta tctggccctg cttgaacagc tgcgacgccg
      361 cctcctctct tccgcggatc ccaccctcag cggcggggga gggggaaagt tttcccctcc
      421 gcaggggctg catggtgcga ggcgacaaca agaccttagg agagtagggg aagaagccaa
      481 cagttgagtt tgctcctgat tatactctgc tgagctggac agagagatca tggagaatgc
      541 aacgtgacca aatgtctcat aatcctgctg ctgtatattc actgccatga tggactgtat
      601 ccattcaaac tggtctccct ctgttgccta tggggaggga tatctctccc aaggctcaag
      661 ggaacctcct gtcttggcct cctgaattaa tgggacttga gagactgcta acatctgaac
      721 atacaaaacc aaacagacaa agtcttgcac cattgctccc cccgcattct actctagagg
      781 aatgccactg tacatggatt ccaaacaggt taaaaagaaa aatagctgat tagatctcag
      841 agtacccagt gaacgggatg acggccacag ctgcagtgga gacaccaaaa atggagaaga
      901 gtgcttccaa ggaagagaag caacagccaa agcaggagga cagcacagac cgaggcaatg
      961 ctgatcctga agaatgggcg aactctgaga gtgaccctga gcagatgagc tgtaagagtg
     1021 gccacaccag ctaccaagcc acagatattc aactgaagaa gaaagagatg ccctctaagc
     1081 cacatcgtcc gctctgtcgg tcaccctgcc tggaccggcc aagcttctcc cagagcagca
     1141 ttttacagga tgggaagcta gacttggaga aagaatacca agccaagatg gattttgctc
     1201 taaagttggg ttatgcagaa gagcaaattc aatcagtgct taataaacta ggcccagaat
     1261 cacttattaa tgatgtatta gcagagcttg tcagacttgg aaacaaaggt gattcggaag
     1321 cacaagtcaa cttgagtcta ttactgcccc gaggagcaag ctccagagag attgcaagcc
     1381 ctgaattgtc tcttgaagat gaaatagaca atagtgataa tttaagacca attgttattg
     1441 atggaagtaa tgtggcaatg agccatggga ataaagaaga attctcctgc aggggaatac
     1501 aacttgctgt ggattggttt ctagacaaag gccataaaga tatcacggta tttgtaccag
     1561 catggagaaa ggagcaatcc cgccccgatg caccaattac agatcaagat attctacgta
     1621 aactggagaa ggaaaagatt ctcgtcttca caccatcgcg aagggtccaa ggcaggaggg
     1681 tggtctgcta tgatgatcgg ttcatagtca aattggcttt cgattctgat ggcatcattg
     1741 tgtccaatga taactaccga gaccttcaag ttgaaaagcc agaatggaag aagtttatag
     1801 aggaacggtt gctgatgtat tcttttgtga atgataaatt tatgccgcca gatgatcctc
     1861 ttggacgcca tggtccgagc cttgagaatt tcttaagaaa gagacctgtg gttcctgagc
     1921 ataagaagca gccatgtcct tatggcaaaa aatgtaccta cggccacaag tgcaaatact
     1981 atcatccgga gcgggccaac caaccccagc gttcggtggc tgatgagctc cgcatcagtg
     2041 ccaaactgtc cacagtgaaa ataatgagtg aagacaccct ggccaaatgt ggcgcaggga
     2101 tgtctactgc caaaggtgag ataacctcag agataaaacg tgtggcctcc aagcgccaat
     2161 cagatcccag catccggtct gtggctgtag agcctgagga gtggctgtcc atcgcccgta
     2221 aacctgaggc cagttctgtc ccttcacttg tgaccgcttt aagtgtccct acaatccctc
     2281 ctcccaaaag ccatgcagtg ggtgcactca acacccgttc agccagcagc ccagtgccag
     2341 ggtcctccca ttttccccat caaaaggcct ctttggaaca catggtcagc atgcaatatc
     2401 cacctatcct ggttaccaac agccatggca cccctattaa ctatactgag caatacccaa
     2461 agtttgagac catgggggac catgactact attcagtgtt aagtgacttc tccaaactga
     2521 gcatcaacaa catgcataat catgaatatt atatggctga ggcaaaccag ggggtatatg
     2581 ttcggaatcc cggcctatgt actgatagtc acatgagcca taccaggaat gacaactatt
     2641 cctcttacaa caacctgtac ttggctgtag ctgatgccca tcctgaaggc actttgaagc
     2701 tgcaccgctc agcatctcat aaccatcttc agcctttttc ccatggttac catgaagcct
     2761 tagcaagagt tcaaagttat ggttccgaag attccaagca agcaccccac aagcagtcag
     2821 tccctcactt agctgtgcat acccagaatc cagcaactgg agcacactct agctgtcctg
     2881 gagactacac catgcctccc agtatccatc ctgtgggacc ctcccagcca ggccgggctc
     2941 tggtgatgac tcgaatggac agcatttctg actcccgcct ctatgacagc aaccccatga
     3001 ggcaaagacg gcctcctctg tgcagagaac agcatgctag ctgggaccca ttgccttgta
     3061 cagccgactc ctatggatac cactcctatc ccttagggaa cagcctcatg caaccgtgtt
     3121 atgaaccagt catggtaagg agcatgcctg aaaaaatgga gcagctttgg aggaatcctt
     3181 gggttggaat gtgcaatgat tctagggagc acatgatacc agagcatcaa tatcagacat
     3241 acaagaacct ctgcaacatc ttcccttcta acattgttct tgcagtgatg gagaagaatc
     3301 cccacacagc agacgctcaa caactggcag ccttgattgt tgccaagctt agagctgcac
     3361 gttgacatga tataggactt attcctttac agaaatatga gtactattaa tacattgata
     3421 ctataattct agtaagtaat aatttgtgtt gtgcgtttaa aattacagag tgttcctatc
     3481 ttttaagtac ataacaactc tgtgaggtag atctcagcaa catttgattt tatagagaag
     3541 gaaacaaaga ttgatgctac caaatgacag tcaagacata cacctaagtt ctctagccca
     3601 atggcccatg cccttttcca ctaaagtgtg gagataatga aggacaaaac ccaggaggcc
     3661 taagtgcaca agaaacccca agggaactca ttaccattat tttctttcca ttttcttttt
     3721 tttagttttt tgagacaggg tctcaccttg taactctggc tttcatgaaa cttgctatgt
     3781 caacctgaac tcagagagcc acctttctct gcctgcagag tgctgggatt gaaggtgtat
     3841 gccaccacac ccagctacct gtattttttc agtcacacat tccatattat aaagtgtgga
     3901 tcatctgtcc agtttagaaa gcaaatacat gaggatcaga ttgtattgtg aattaacttt
     3961 taagggtttt tgttgttgtt gttattgttg gtttcttgag acagggtttc tctgtgtagc
     4021 cctggctgtc ctggaactca ctctgtagac caggctggcc tcgaactcag aaatccacct
     4081 gcctctgcct cccaagtgct gggattaaag gcgtgcgcca ccactgccca gctaaggttt
     4141 ttgttttagt ttttttaaat agaaatcttt aaaatcaaaa gtaacatgat tttattgcat
     4201 gggtatctga tcattcaata tctttaacca gtatagggtc acattgaggc ttctagagaa
     4261 atagatgaac cttcctctta gcaattctac tgcatgtatg aatttacgta tttggtttca
     4321 gatgtgtttg tctctctggt atcaactttt ctatagtgac aagatgggaa gttctataca
     4381 gtctatagtt tacatctgta tagatcacac atacaacttg attttgtcac aattttatag
     4441 tttcaattcg attcaaaagt gaaatcacat gtcgacattt aaattttgct ttcttaaaga
     4501 ccagagtaaa gcagctgtat ttcttctaca tattttactt gaccacattt attaaccatt
     4561 cttagctttc agaaagtctt ttcaccttag caaattaggg gtcaggctga agccttctat
     4621 agaggaacta gtctatgagc ttatgttcaa cacttagtat gtatatcata cacaagtgct
     4681 caagagctgg accaggacca agggacttac atagcagaat ctactgccct tatcctggga
     4741 gggatggcat tcagtgatag ctacagagtt ggaaattctg acaaattcaa cattacagga
     4801 caatgtgtag tgaaagagag tgcagaggca tacaagccac tgtctctagc tgtccaccat
     4861 ttgagcaata agatcagtaa tcaatagagc agaatgtctt taggaaacca aaccagggta
     4921 ttttctaggt ggcaaaagca gtttccaaag gggaagtgtt ctgctacgca cttcaaaccc
     4981 atgcaaagag ggtgcactgg attagctcat actgaaaggc attattaaat gggccaggca
     5041 gcaccatttg cacaatttga atcttattct aggtagaatc atttgtagct acatgcctct
     5101 agaaggggca tttattgttt tttggttttt ttttcatttt tgtttttttt taagatgcat
     5161 taaatgagcc ctcctttctg aattcactgt atatttcaac attttgaacc atgaccagct
     5221 cccaatttct gaggctggca cttactaact tctacagtcc tttttcatga gagttgagaa
     5281 ggcctggcct tggccttttg tttcttcatg agaaggtgta atactgccta taaatgtttc
     5341 ttactgtgaa acactctgac tgtgaggctg tagtcagggt tgtttctggt ggtttgataa
     5401 tggcttccat gctgctttcc agctttctct ctctgtgaaa gttgatgaat agtacatctt
     5461 aatcagtatt cacttagcca cgattttaca tctgtctctt cctaccctct aatagttcca
     5521 ttccccagta tactgataaa gtgtaacaat attttctatc gagtgggccc agcaaacttg
     5581 acagttgcct ctgcagtgct tgttgtctca cacaagcacc tcttcatacc ttgaacttct
     5641 tggaccttct aaatcttccc cttgactaga tcagggtatt tgacaatctc agagtattcc
     5701 gatgccttcg tacaattagt tcatcttcct accaatgaca ctgcagtgtc cattggcttc
     5761 ccaatttgtg gggaaagccc aagattcgtc ttgtcagctg caattcatct ggaatatgtt
     5821 catgtttaaa attcaaagaa aaataaatag taagctcctc ccagtcaggg gaattttttt
     5881 agagatagca tatggatttt ttactttcta agaaaggatt gcctttgttc tctccttgta
     5941 aaatgtggat gaaccaaagc agctaagagc aatgcctcaa ataaccagaa atgacctttc
     6001 gttgatacaa attgtatctc tttttctcct gattgtatag aaacaagtat acaaaactca
     6061 tcttaaacta tgtttagtac ttaattttca ccatatttgt ggcactgtgt gtcacaggaa
     6121 agtagcccag gggtgacgag ggagctttta tttccaaagg gcagtagtag tttatagaca
     6181 aatacagttt tcaaggcctc tttattgtta gatgcacaac tactgtgtgt acaatctgca
     6241 acattgtgat tctctttagc ctattaaatt taatatgtcc ttgtaaaagg gatttttata
     6301 aagtgtcaat agtaatacac catatgtaag aatccttaag gagctgtata aatatgaatg
     6361 cataaatcca acttggttct tacattagag aaacattttt tatatcaaga tctgcatact
     6421 tcttgacttt tccattttgt ctataattat aaaatagcaa ataaagaaga gcattgagac
     6481 ctc
//
