LOCUS       NM_134003               2096 bp    mRNA    linear   ROD 08-JUN-2024
DEFINITION  Mus musculus zinc finger CCCH type containing 10 (Zc3h10), mRNA.
ACCESSION   NM_134003
VERSION     NM_134003.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2096)
  AUTHORS   Audano,M., Pedretti,S., Ligorio,S., Gualdrini,F., Polletti,S.,
            Russo,M., Ghisletti,S., Bean,C., Crestani,M., Caruso,D., De
            Fabiani,E. and Mitro,N.
  TITLE     Zc3h10 regulates adipogenesis by controlling translation and
            F-actin/mitochondria interaction
  JOURNAL   J Cell Biol 220 (3) (2021)
   PUBMED   33566069
  REMARK    GeneRIF: Zc3h10 regulates adipogenesis by controlling translation
            and F-actin/mitochondria interaction.
REFERENCE   2  (bases 1 to 2096)
  AUTHORS   Yi,D., Nguyen,H.P., Dinh,J., Viscarra,J.A., Xie,Y., Lin,F., Zhu,M.,
            Dempersmier,J.M., Wang,Y. and Sul,H.S.
  TITLE     Dot1l interacts with Zc3h10 to activate Ucp1 and other thermogenic
            genes
  JOURNAL   Elife 9, e59990 (2020)
   PUBMED   33107819
  REMARK    GeneRIF: Dot1l interacts with Zc3h10 to activate Ucp1 and other
            thermogenic genes.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2096)
  AUTHORS   Yi,D., Dempersmier,J.M., Nguyen,H.P., Viscarra,J.A., Dinh,J.,
            Tabuchi,C., Wang,Y. and Sul,H.S.
  TITLE     Zc3h10 Acts as a Transcription Factor and Is Phosphorylated to
            Activate the Thermogenic Program
  JOURNAL   Cell Rep 29 (9), 2621-2633 (2019)
   PUBMED   31775033
REFERENCE   4  (bases 1 to 2096)
  AUTHORS   Audano,M., Pedretti,S., Cermenati,G., Brioschi,E., Diaferia,G.R.,
            Ghisletti,S., Cuomo,A., Bonaldi,T., Salerno,F., Mora,M.,
            Grigore,L., Garlaschelli,K., Baragetti,A., Bonacina,F.,
            Catapano,A.L., Norata,G.D., Crestani,M., Caruso,D., Saez,E., De
            Fabiani,E. and Mitro,N.
  TITLE     Zc3h10 is a novel mitochondrial regulator
  JOURNAL   EMBO Rep 19 (4) (2018)
   PUBMED   29507079
  REMARK    GeneRIF: our study identifies Zc3h10 as a novel mitochondrial
            regulator.
REFERENCE   5  (bases 1 to 2096)
  AUTHORS   Guo,G., Huss,M., Tong,G.Q., Wang,C., Li Sun,L., Clarke,N.D. and
            Robson,P.
  TITLE     Resolution of cell fate decisions revealed by single-cell gene
            expression analysis from zygote to blastocyst
  JOURNAL   Dev Cell 18 (4), 675-685 (2010)
   PUBMED   20412781
REFERENCE   6  (bases 1 to 2096)
  AUTHORS   Guardiola-Serrano,F., Haendeler,J., Lukosz,M., Sturm,K.,
            Melchner,Hv. and Altschmied,J.
  TITLE     Gene trapping identifies a putative tumor suppressor and a new
            inducer of cell migration
  JOURNAL   Biochem Biophys Res Commun 376 (4), 748-752 (2008)
   PUBMED   18814840
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB842371.1, AK050662.1, BY441443.1 and AC117232.3.
            
            On Feb 7, 2019 this sequence version replaced NM_134003.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC022677.1, AK031312.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164138 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-365               BB842371.1         21-385
            366-2060            AK050662.1         358-2052
            2061-2093           BY441443.1         359-391
            2094-2096           AC117232.3         29136-29138         c
FEATURES             Location/Qualifiers
     source          1..2096
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 77.01 cM"
     gene            1..2096
                     /gene="Zc3h10"
                     /note="zinc finger CCCH type containing 10"
                     /db_xref="GeneID:103284"
                     /db_xref="MGI:MGI:2143670"
     exon            1..53
                     /gene="Zc3h10"
                     /inference="alignment:Splign:2.1.0"
     exon            54..117
                     /gene="Zc3h10"
                     /inference="alignment:Splign:2.1.0"
     exon            118..2096
                     /gene="Zc3h10"
                     /inference="alignment:Splign:2.1.0"
     CDS             170..1477
                     /gene="Zc3h10"
                     /codon_start=1
                     /product="zinc finger CCCH domain-containing protein 10"
                     /protein_id="NP_598764.1"
                     /db_xref="CCDS:CCDS24281.1"
                     /db_xref="GeneID:103284"
                     /db_xref="MGI:MGI:2143670"
                     /translation="MPDRDSYANGTGSSGGGPGGGGSEEASGAGTGSGGATSDAICRD
                     FLRNVCKRGKRCRYRHPDMSEVSNLGVSKNEFIFCHDFQNKECSRPNCRFIHGSKEDE
                     DGYKKTGELPPRLRQKVAAGLGLSPADLPNGKEEVPICRDFLKGDCQRGAKCKFRHLQ
                     RDFEFDARGGGGTGGGGSTGSAPPGRRHDLYDIYDLPERGFEDHEPGPKRRRGGCCPP
                     DGPHFESYECNLAPLRGVECRLLEEENALLRKRVEELKKQVSNLLATNEVLLEQNAQF
                     RNQAKVMTLSSTAPATEQTLAPTVGTVATFNHGIAQTHTTLSSQALQPRPVSQQELVA
                     PTGAPAAPPTNAAPPAAPPPPPPHLNPEITPLSAALAQTIAQGMAPPPVSMAPVAVSV
                     APVAPVAVSMAQPLAGITMSHTTTPMVTYPIASQSMRITAMPH"
     regulatory      2066..2071
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zc3h10"
                     /note="hexamer: AATAAA"
     polyA_site      2088
                     /gene="Zc3h10"
                     /note="major polyA site"
ORIGIN      
        1 gtcgaagcta gaggaccggc aggcggcagc agcaactacg gcggcggcgg cagaacccag
       61 cagtgatgtg gaggtggaga ctcacgggag ccccggactt cacctgagct acctcagtcg
      121 ccaagagtgg caagaaaagg aagaagaccc tgacttgggg gggaccagga tgcctgaccg
      181 ggacagctat gccaacggca ctggcagcag cggtggaggc cctggaggtg gtggcagtga
      241 ggaggccagt ggggcaggga caggcagcgg gggagccacc tcagatgcca tctgtagaga
      301 cttcctgagg aacgtctgca aacgaggcaa gcgatgtcga taccgccacc cagacatgag
      361 tgaggtatcc aatttggggg taagcaaaaa tgaatttatc ttctgccatg acttccaaaa
      421 caaggagtgt agccgcccca actgtcgttt catccacggc tccaaggagg atgaggatgg
      481 ctataagaag acaggagagc tgcctccccg gctgaggcag aaagtggccg ctgggctggg
      541 tctctcaccc gccgacctac ccaatggtaa ggaggaggtc cccatctgcc gcgacttcct
      601 caaaggtgac tgtcagagag gagccaagtg caagtttcgt cacctgcaaa gggattttga
      661 gtttgatgct cgcggtggag gaggcactgg aggtggaggc tccacaggct ctgctccccc
      721 aggacgccgt catgatctct atgacatcta cgaccttccg gaaaggggct ttgaggacca
      781 cgaaccaggc cctaagcgcc ggagaggtgg ctgctgccct cctgacggcc cccatttcga
      841 gtcctacgaa tgtaacttgg ctccgctccg tggggttgag tgcagactgc tggaggagga
      901 gaacgccctg ctcaggaaac gcgtggagga gctgaagaag caggtcagca acctgctggc
      961 caccaatgag gtacttctgg agcagaatgc ccagttccgg aatcaggcca aggtgatgac
     1021 tctgagctcc actgcccccg cgactgagca gaccctggcc cccactgtgg gcacagtggc
     1081 cacttttaac catggcatcg cccagactca taccactctg agcagccagg ctctacagcc
     1141 tcggcctgtg tcccagcaag aacttgttgc tcccacaggg gcaccggctg ctcccccgac
     1201 taatgctgca cctcctgccg ctccgccgcc cccacctcca cacctgaacc ccgagatcac
     1261 gccgctgtca gccgctctgg ctcagaccat cgcccagggg atggcacccc cacctgtttc
     1321 catggcccct gtagctgtgt ctgtggctcc tgtggctcct gtggctgtgt ccatggccca
     1381 gcccttagca ggaatcacaa tgagccacac cactactcct atggtgactt accccattgc
     1441 ttcccagagc atgcgcatca cagccatgcc acactgacag gactaatgga tactctactc
     1501 cctgttacag catccgaggg ctggggtcac ggggcccttc cccacttgca tagccctccc
     1561 aggctctgtc cgaagggcca ctcagaaact aggacaagag actacaagga atatacttgg
     1621 taggagcatc tcctgaggca gggttgtgct ggtgtgttct ccccactctt gagaggggtc
     1681 tctccttcag gcctcaactc aaacaggctt gcacaggagt ggagacttga gccggcagag
     1741 agaaaggact gagggactgt cttttctcat aggaagttgg gggtgtccct ggtcttgttt
     1801 tcattgtgaa cagcacagat tccagcactg gtgtgggaga gagaaattcc ccacccagac
     1861 agagagccag gaaagatgga gaaagtgaaa gtcagtggtc aggagcaaag acctcatatg
     1921 agccttcaga tggttcgggg cccaaaaaca ctcctgggcc cctgggaagg ctgggaccat
     1981 agtactcaaa cccagagtag gggaacattc acttacctcg cttggcctgg aaatctgtag
     2041 ggcagtgccc actactttcc aaagaaataa aagaacgtta ttttttaaca aaagtg
//
