LOCUS       NM_172414               4482 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus zinc finger, C2HC-type containing 1C (Zc2hc1c), mRNA.
ACCESSION   NM_172414
VERSION     NM_172414.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4482)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4482)
  AUTHORS   Hoffman,B.G., Zavaglia,B., Witzsche,J., Ruiz de Algara,T.,
            Beach,M., Hoodless,P.A., Jones,S.J., Marra,M.A. and Helgason,C.D.
  TITLE     Identification of transcripts with enriched expression in the
            developing and adult pancreas
  JOURNAL   Genome Biol 9 (6), R99 (2008)
   PUBMED   18554416
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BX525619.1, AK032455.1, AK036602.1 and AC159237.2.
            
            On Nov 17, 2009 this sequence version replaced NM_172414.3.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK036602.1, AK033213.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-546               BX525619.1         26-571
            547-2536            AK032455.1         451-2440
            2537-2852           AK036602.1         2475-2790
            2853-4482           AC159237.2         206268-207897
FEATURES             Location/Qualifiers
     source          1..4482
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 39.63 cM"
     gene            1..4482
                     /gene="Zc2hc1c"
                     /gene_synonym="2810002I04Rik; Fam164c"
                     /note="zinc finger, C2HC-type containing 1C"
                     /db_xref="GeneID:72350"
                     /db_xref="MGI:MGI:1919600"
     exon            1..195
                     /gene="Zc2hc1c"
                     /gene_synonym="2810002I04Rik; Fam164c"
                     /inference="alignment:Splign:2.1.0"
     exon            196..1525
                     /gene="Zc2hc1c"
                     /gene_synonym="2810002I04Rik; Fam164c"
                     /inference="alignment:Splign:2.1.0"
     CDS             215..1798
                     /gene="Zc2hc1c"
                     /gene_synonym="2810002I04Rik; Fam164c"
                     /note="protein FAM164C; family with sequence similarity
                     164, member C"
                     /codon_start=1
                     /product="zinc finger C2HC domain-containing protein 1C"
                     /protein_id="NP_766002.2"
                     /db_xref="CCDS:CCDS26056.1"
                     /db_xref="GeneID:72350"
                     /db_xref="MGI:MGI:1919600"
                     /translation="MAGLQLAPHLPVGVMFPHNKTEAPGLHSAKHDPYEQSDSSQRPS
                     MGHLRNSFQSKLWSNTEMEQEDEVSTRPKRNVCTKARRHSCPHSAGIRQQGSGNNAQG
                     QGKGLFYLSSPTPRYPKANDQDFIPFRRKRVGVDRAYPLKPMVHRKSHSTSDAGADGD
                     QNGYPRLPDSSEFSDNSFGLRSWVNSSLLASVQAEKVVAELHRTEWTQIQRLEAAGES
                     LQKEIRRKEILLQEKLKKTEEGLRRMQKEKKQAIFQEDRELQRMVLPRRRVRDGDHDT
                     PHKPCLSPEFRSEVFSRNRGEDQTCDQAQENPSPRQLSDYELQKLKRERLMASNSKIR
                     DQDAGPSADAFFQPAEELGSTLQESSRSGTPGSSGSSSSTEEPELAKCSHCGRSFLSL
                     RLQRHSTVCGKMQGSKRKVFDSSRARAKGTELEQYLNWRGPATAKAETPPPPRKSTWR
                     QKHESFIRTLRHARQVQQVIARGGNPSDLPSILPADNPDYVQCPHCSRHFAPKVAERH
                     IPKCKTIKNRPPPPRRHDS"
     exon            1526..4482
                     /gene="Zc2hc1c"
                     /gene_synonym="2810002I04Rik; Fam164c"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2046..2051
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zc2hc1c"
                     /gene_synonym="2810002I04Rik; Fam164c"
                     /note="hexamer: ATTAAA"
     polyA_site      2072
                     /gene="Zc2hc1c"
                     /gene_synonym="2810002I04Rik; Fam164c"
                     /note="major polyA site"
     regulatory      2224..2229
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zc2hc1c"
                     /gene_synonym="2810002I04Rik; Fam164c"
                     /note="hexamer: TATAAA"
     polyA_site      2247
                     /gene="Zc2hc1c"
                     /gene_synonym="2810002I04Rik; Fam164c"
     polyA_site      2471
                     /gene="Zc2hc1c"
                     /gene_synonym="2810002I04Rik; Fam164c"
     polyA_site      2539
                     /gene="Zc2hc1c"
                     /gene_synonym="2810002I04Rik; Fam164c"
ORIGIN      
        1 gattgcttgt ggactgcgcc tgcgcacatc tggagctaaa agttctcaac cagaggcggt
       61 gctctggtct ccaggcaacg ggataacaga ggtggacaga gagcgcctgc gtggacggcg
      121 gttgggttta gtcaggtgtg gaaaactagg tcttggggat tttccctgag ctggagcggc
      181 ccccgagcgc ctcaggcttc ggtccaggca ctgaatggct ggtctccagt tggctccaca
      241 tctgcctgtg ggcgttatgt tcccacataa taaaacagaa gctcctggac tccactcagc
      301 taagcacgac ccttacgaac aaagtgactc ttcccagcgg ccctcgatgg gacatttgag
      361 gaatagtttc cagtcgaagc tttggagcaa cacagaaatg gagcaggagg acgaggtctc
      421 cacccgcccc aaaaggaacg tctgcacaaa agcccggagg cactcctgtc cccacagtgc
      481 aggaatcagg cagcaaggct cagggaacaa tgcccagggc caaggaaagg gtctgtttta
      541 cttgtctagt ccgacacccc ggtatcccaa agcaaatgac caggacttca ttccctttag
      601 gaggaaacga gtgggagtgg atcgggctta cccactgaaa cccatggtcc accggaagtc
      661 acatagtaca agtgatgcgg gcgcagacgg ggaccagaat ggctacccaa gactccctga
      721 ctcaagtgag ttttcagaca acagctttgg tttaaggagc tgggtgaatt catctcttct
      781 tgcctctgtg caggcagaga aggtcgtggc ggagctccat aggaccgagt ggacccagat
      841 ccaaaggctc gaagctgcag gggagagttt acagaaggag atccgcagaa aggagattct
      901 cctacaagaa aagctgaaga agacagagga gggtcttcga aggatgcaga aggaaaagaa
      961 acaggccatt ttccaggaag acagagagct acaaaggatg gtactaccta gaaggagggt
     1021 tcgagatggt gaccatgaca ccccacacaa accctgcttg tccccagagt tcaggtctga
     1081 ggtattcagt agaaacaggg gagaggatca aacttgtgat caggctcagg aaaaccctag
     1141 tccacgccag ctctctgatt atgaactcca aaagctcaaa agggaaagac tgatggccag
     1201 taacagtaaa atccgagatc aagacgcagg accctcagca gacgcgttct ttcaaccggc
     1261 agaggagctg ggcagtacac tgcaggagtc aagtcggtcc gggacaccag gctcctctgg
     1321 gtccagctcc tccacagaag agccagagct ggccaagtgc agccactgtg gacgatcgtt
     1381 tctttccctc aggctgcaga gacactccac cgtctgtggc aagatgcaag ggtccaaaag
     1441 aaaagtgttt gactcttcca gggcccgggc gaagggcaca gaactagagc agtacttgaa
     1501 ctggagggga ccagccacag ccaaggctga aactccgcct ccccctcgga agagcacctg
     1561 gagacagaag cacgagtctt ttatccgtac cctccggcat gcgcgacagg tccagcaggt
     1621 aatcgccaga ggtggcaatc cctcagactt gccttccatc ctgcctgcag acaacccaga
     1681 ctatgttcag tgtcctcact gcagccgcca ctttgctccc aaggtggctg aacgccacat
     1741 acctaagtgt aagaccatca agaaccgacc accgccgcca aggaggcacg acagctgagc
     1801 agaaaatggc agaaaccaac cccactcagg ctgtgcttcc cttcagcagt aaaccagaga
     1861 gtaagggatg ggaagcaggg agataaactt ctccagagct caggatctgc ctgcggggca
     1921 aattgacccc tgagggcagc cactgctacg tggcaagaga caaacagaag ccccagcttc
     1981 tcactgaatc agaacttggc tgagtgttta tgttcttgcc tgaagacttg gtaggtgagg
     2041 actgcattaa agctctcttt tcctgagcct gaccatggtt tgtgctggtg aagtgcccca
     2101 atccgcatcc cctggccacg gcacatgtcc aggggttctg ttagcccttc ttgctcttga
     2161 aaattgggat ataaagaaga gagagtgggg tcggagtact actgtcacac agatggtaac
     2221 tcttataaaa ggcagttcga ctatgcagtg aggtgctcat aatggaagtc tgttcttggc
     2281 ctccatgggc cacagtcctg gctgaaagcc aacaaaagta tggaccgtta gggaaccagt
     2341 gtatcctaac ccttccctgt ggtgtactgt ataatgaaat agctttatgc tcttcacaga
     2401 gtaggggtgg gtagaaaagt tttacttctc tgtacttgtt ctctttaaat gtgtttccta
     2461 tgttgatgga agaagtggct ggtatccttt caaatatgac tgtgtggctg tccgcctcga
     2521 ggcagcagag cctgtctaag caagtgtgga caatgctcac tgtttttcat ggcccagaga
     2581 tcagaacata gtcgtgcttc tattttaaac tctgaaaggg atcaggtctt cttaaccgtg
     2641 ggaagagtgc ccacttcaag ttaggccttc aactaatgga tttggggagc ttaagaaggt
     2701 tggctgctta agctcttagg accactgggt ctttaacctg acatgccctc tcccccaggc
     2761 aagttcactg aggagtacac aatgttcttt attccatgta acaaatacgc cacggctaaa
     2821 atcacaaggt cgcatcccca cagatgttca gagtttaaaa tgatttacga gtgttttgac
     2881 cacatgtatg tatgtgcacc atgtgcacgc ctggtgcctg cagaagtcag agggtgttgg
     2941 atctccagat actggagctg cagatggttg tgggtcacca tgtgtgtgct gaggacccag
     3001 gtcatctaca agagcaacaa gtggtcttaa cctcagagcc atctctccag cacccccacc
     3061 ccattcatat aacattcata aatgttacga agcatttcaa atgatcttct gaccctgggg
     3121 taggagcatg tcttggcaat ctggaggctg tggaaacact gggcagcaac ctacacgggg
     3181 cacactggaa ggagttcaaa atctgctgct ctgctccttc tagagggaat gatggcagac
     3241 agaaccagat tccctgcctc atctgctggg cctcctgagc ataaggattt gggatccatt
     3301 atgatgttat tagagtcata ggttagagct ctcaagaggg aacaagtgtg tgtagggctt
     3361 tctccagacg tggcacttac tcatttttaa ggtaccaagg agaaaacaag cagctgtctt
     3421 tgtattccct gcgaccttga ttgtcagcct tgggaattta gctagctcca actctggggg
     3481 agggaagggc cccgttacaa gctcaactag agatcacgca ggtactgctt gccaatgtcc
     3541 atggacttta agcacacgtc gtaaacagta tacattttaa agttccaaag ctctgggaaa
     3601 ttctcacagt caaactcctg aggtgctctt tccatttaga aatgtgtgca gacatgttgg
     3661 ggcaaagact tcctagttca catagcacag tgcctcttgt caacatttgc tttcggtcag
     3721 ttgatcattc ttcacaacca cacagatggc aagcagagct gggatgtaga tcttcctcct
     3781 caaagcccat gacccgtgag gtttaatgac cggcgtattt atgtcggcag ttaatcactg
     3841 aggcaataaa tgacttctgg ctttgcaggg catctcagag tcctgaccct gcctcctgct
     3901 atcatgactg gtacttcctt tgaggcctgg ggatctcata taagtaactt tctctaaaat
     3961 acatattttt tttccttggc tgttcctccc atcataaatg tttctgaata gataacaaac
     4021 cagatgaaat ttgagcatta gaagcctttt gctttaaact ttagtgtgat gttcagccaa
     4081 gagcaacagc tgttgtgcca aggagaccaa gttcaactca gctttcttga ggaagtttta
     4141 tagacaaact ggcatgatca cttggaaaag tctccccatg agaaccaagg aggtgtgtag
     4201 aactctgatt cttctcaatg ttatgtaggc ccatggtgtg tatgagtgca ggcatgcaca
     4261 cgccagtgtg tgagaccaca cacagctgtg tggactctgt aggttggact ctggtcacct
     4321 tgagtgccta gcaagccact cttgacctgc tgacaatcct tcctttaatg gcttttcccc
     4381 cttctgcact ttctaaattt ttacaaactt ctggggaaaa aattgtttgc tttttttttc
     4441 tggcaagaat gagattggaa aacagcagag attatttccg tg
//
