LOCUS       NM_173399               4360 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus zinc finger and BTB domain containing 5 (Zbtb5),
            transcript variant 3, mRNA.
ACCESSION   NM_173399
VERSION     NM_173399.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4360)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4360)
  AUTHORS   Medeiros de Araujo,J.A., Barao,S., Mateos-White,I., Espinosa,A.,
            Costa,M.R., Gil-Sanz,C. and Muller,U.
  TITLE     ZBTB20 is crucial for the specification of a subset of callosal
            projection neurons and astrocytes in the mammalian neocortex
  JOURNAL   Development 148 (16) (2021)
   PUBMED   34351428
REFERENCE   3  (bases 1 to 4360)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   4  (bases 1 to 4360)
  AUTHORS   Guo,G., Huss,M., Tong,G.Q., Wang,C., Li Sun,L., Clarke,N.D. and
            Robson,P.
  TITLE     Resolution of cell fate decisions revealed by single-cell gene
            expression analysis from zygote to blastocyst
  JOURNAL   Dev Cell 18 (4), 675-685 (2010)
   PUBMED   20412781
REFERENCE   5  (bases 1 to 4360)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   6  (bases 1 to 4360)
  AUTHORS   Sharov,A.A., Piao,Y., Matoba,R., Dudekula,D.B., Qian,Y.,
            VanBuren,V., Falco,G., Martin,P.R., Stagg,C.A., Bassey,U.C.,
            Wang,Y., Carter,M.G., Hamatani,T., Aiba,K., Akutsu,H., Sharova,L.,
            Tanaka,T.S., Kimber,W.L., Yoshikawa,T., Jaradat,S.A., Pantano,S.,
            Nagaraja,R., Boheler,K.R., Taub,D., Hodes,R.J., Longo,D.L.,
            Schlessinger,D., Keller,J., Klotz,E., Kelsoe,G., Umezawa,A.,
            Vescovi,A.L., Rossant,J., Kunath,T., Hogan,B.L., Curci,A.,
            D'Urso,M., Kelso,J., Hide,W. and Ko,M.S.
  TITLE     Transcriptome analysis of mouse stem cells and early embryos
  JOURNAL   PLoS Biol 1 (3), E74 (2003)
   PUBMED   14691545
REFERENCE   7  (bases 1 to 4360)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: III. the complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (4), 167-180 (2003)
   PUBMED   14621295
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC057545.1 and BC054551.1.
            
            On Jul 15, 2009 this sequence version replaced NM_173399.2.
            
            Transcript Variant: This variant (3) differs in the 5' UTR,
            compared to variant 1. Variants 1-3 encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC054551.1, SRR1660815.239268.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-142               BC057545.1         1-142
            143-2580            BC054551.1         1-2438
            2581-2595           BC057545.1         3853-3867
            2596-4360           BC054551.1         2455-4219
FEATURES             Location/Qualifiers
     source          1..4360
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 23.66 cM"
     gene            1..4360
                     /gene="Zbtb5"
                     /gene_synonym="5930421I10; 9430083K24Rik; mKIAA0354"
                     /note="zinc finger and BTB domain containing 5"
                     /db_xref="GeneID:230119"
                     /db_xref="MGI:MGI:1924601"
     exon            1..189
                     /gene="Zbtb5"
                     /gene_synonym="5930421I10; 9430083K24Rik; mKIAA0354"
                     /inference="alignment:Splign:2.1.0"
     exon            190..4334
                     /gene="Zbtb5"
                     /gene_synonym="5930421I10; 9430083K24Rik; mKIAA0354"
                     /inference="alignment:Splign:2.1.0"
     CDS             194..2206
                     /gene="Zbtb5"
                     /gene_synonym="5930421I10; 9430083K24Rik; mKIAA0354"
                     /note="expressed in brain and neural tube; transcription
                     factor ZNF-POZ"
                     /codon_start=1
                     /product="zinc finger and BTB domain-containing protein 5"
                     /protein_id="NP_775575.2"
                     /db_xref="CCDS:CCDS18129.1"
                     /db_xref="GeneID:230119"
                     /db_xref="MGI:MGI:1924601"
                     /translation="MDFPGHFEQIFQQLNYQRLHGQLCDCVIVVGNRHFKAHRSVLAA
                     CSTHFRALFSVAEGDQTMNMIQLDSEVVTAEAFAALIDMMYTSTLMLGESNVMDVLLA
                     ASHLHLNSVVKACKHYLTTRTLPMSPSSERAQEQSARMQRSFMLQQLGLSIVSSALSS
                     SQSAEEPTAPMSSSMRSSLDQRTPFPMRRLHKRKQSVEERARQRLRSSMEESAISDVT
                     PESGPAGVHSREEFFSPDSLKIVDNPKPDGMADNQEDGAMMFDRPFGAQEDAQVPSQS
                     DGSAGNMASRATQVETSFEQEAVAEKGSFQCENPEVGLGEKEHMRVVVKSEPLSSPEP
                     QDEVSDVTSQAEGSESVEVEGVVVSAEKIDLSPESSDRSFSDPQSSTDRVGDIHILEV
                     TNNLEHKTSFSISNFLNKSRGSNFSASQSTDDNLPNTTSDCRLEGEAPYLLSPEAGPA
                     GGPSSAPGSHVENPFSEPADSHFVRPMQEVMGLPCVQTSGYQGEQFGMDFSRSGLGLH
                     SSFSRAMMGSPRGGASNFPYYRRIAPKMPVVTSVRSSQISENSASSQLMMNGATSFEN
                     GHTSQPGPPQLTRASADVLSKCKKALSEHNVLVVEGARKYACKICCKTFLTLTDCKKH
                     IRVHTGEKPYACLKCGKRFSQSSHLYKHSKTTCLRWQSSNLPSTLL"
     regulatory      4304..4309
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zbtb5"
                     /gene_synonym="5930421I10; 9430083K24Rik; mKIAA0354"
                     /note="hexamer: ATTAAA"
     polyA_site      4334
                     /gene="Zbtb5"
                     /gene_synonym="5930421I10; 9430083K24Rik; mKIAA0354"
                     /note="major polyA site"
ORIGIN      
        1 ggcctccgcc gggtcctcaa agaaccgcgc gaacgggctg aaggagccgg gagcgagggg
       61 cggggcgggc ggaagtcaca gccggggaag ccagtctgga ccttcccgcc tccttcctca
      121 gggtcggtcc gagcggagga gggccaccgc ctcctcctgc gaggagaagg ggggcggagc
      181 ccggctcagg acaatggatt ttcctggtca ctttgagcag atctttcagc agctgaacta
      241 ccagagactt catgggcagc tgtgtgactg tgtcattgta gtggggaaca ggcatttcaa
      301 agcccaccgc tccgtgctgg cagcatgcag tacgcatttc cgagcactgt tctcggtggc
      361 ggaaggagat cagaccatga acatgatcca gctagatagt gaggtggtga cagccgaggc
      421 cttcgccgcc ctgattgaca tgatgtatac ctccaccctc atgctagggg agagcaacgt
      481 tatggatgtc ttattggcag cctctcacct gcatctgaac tccgttgtta aggcatgtaa
      541 acattacctg acgacaagga cgctccccat gtctccctct agtgagcgtg ctcaggagca
      601 gagtgcccgc atgcagcgct cttttatgct gcagcagctg ggactcagca ttgtgagctc
      661 agccctcagt tccagccaga gtgccgagga gccgacagcc cctatgagct catccatgcg
      721 cagcagcctg gaccagcgga cacccttccc catgagacgc cttcacaagc gcaaacagtc
      781 tgtagaggag cgggcccggc agcgcctgcg atcctccatg gaggaatctg ccatttcaga
      841 tgttactcca gagagcgggc ctgcgggagt tcattcccgg gaggaattct tctcaccgga
      901 ttctctgaaa attgtggata atcctaaacc cgatgggatg gctgacaacc aggaagacgg
      961 tgccatgatg tttgatcggc cttttggtgc ccaagaagat gctcaagtgc ccagccagtc
     1021 agatggcagt gctggcaaca tggcctctcg tgcaactcag gttgaaacga gttttgaaca
     1081 agaggccgtg gctgagaaag gcagtttcca gtgtgaaaat cctgaggttg gcctcgggga
     1141 gaaggagcac atgagagtgg tggtgaagtc tgagcccctg agctctcccg agccgcagga
     1201 tgaagtgagc gacgtgacct cccaagcaga gggcagtgag tctgtggagg tggaaggagt
     1261 ggtggtcagt gccgagaaga tagacctcag ccctgaaagc agtgaccgga gcttttccga
     1321 tccccagtcc agcaccgaca gggtcgggga catccacatc ttggaagtca cgaataatct
     1381 agaacataag acctctttta gtatttccaa ttttctcaac aagagcaggg ggagtaattt
     1441 cagtgcaagt cagagcactg acgacaacct cccaaacacc accagtgact gtaggctcga
     1501 gggcgaggcc ccttatctgt tgagtccaga ggctgggcca gcaggtgggc cttcctctgc
     1561 ccctggttcc catgtagaga acccgttcag tgagcctgca gactcccact tcgtcagacc
     1621 tatgcaggag gtgatgggcc tgccctgtgt gcagacctca ggctaccaag gagaacaatt
     1681 cgggatggat ttttccaggt ctggcttggg tctccactca tccttctcca gggccatgat
     1741 gggttcccca cgaggagggg ccagtaactt tccatattac cgacgaatag ctccaaaaat
     1801 gccagtggta acttctgtca ggagctcgca gatctctgaa aattcagcca gttcccagct
     1861 aatgatgaac ggggccacct catttgaaaa tggccacacc tcccagcctg gccctcctca
     1921 gttgaccagg gcatctgctg atgtcttgtc aaagtgcaag aaggccttat cggagcacaa
     1981 tgtcttggtt gtggagggag ctcgaaagta tgcctgcaaa atctgctgta aaaccttcct
     2041 gactctgacg gattgcaaga aacacatccg ggtccacaca ggagaaaagc cgtacgcctg
     2101 cctcaagtgt ggcaaacggt tcagtcagtc cagccaccta tataaacact cgaaaacgac
     2161 ctgcctgcgc tggcagagca gcaacctccc cagcaccctg ctctgatcgc ttctcgccac
     2221 agcgcacagg ccagtctgca ctgaaactaa aaccgctgta ggcaggcagc tcttgtcact
     2281 ggactcggtc tcactgtcca gtggctctca tgaatttcag ccaagagtaa gcagagaact
     2341 gttaggtgta gcacttaccc tgcacatttc ttagggtgga ggaatgcagt cctaaagtag
     2401 gttgtcattg ttgttaagaa tatcaaattt aaaaatgaaa gtgcagaaaa cattttaaca
     2461 ctattttaaa gctctgtgaa gcatttaatt aaatgtcctg tatcctgtga tgggagtatt
     2521 ccatccctgt acagcaatgc agaacatact gtgtgtaacc aggtgacttg gtgctatctg
     2581 gaaaaaaaaa aaaaaggccc tggaggacaa gcatgtctgg cacagatgct taaagtgtat
     2641 cctgagctag tcccaggcct ctgaaagtcc tgtggagttt ttatttgtat ctgagttgca
     2701 gtcacaggca ctgccctctg atggtgctca cactgagtcc agggaaatat gcccttggac
     2761 taacaggtgt atagactttc gaatacatct ctatggcata ggtgttttta gtaacttttc
     2821 tgtttgtttt aagaactaaa gttgtaatgg agtgtgtact tgtaggagtg acagtgaggt
     2881 gtttctgttc gtgctgtgtt agcagggttt taaccaacgt gtatttctga tactgtactt
     2941 gtttgatgta agtgggaagc tagtgtccgt ctttcctctg gtgatacgga gtcctgtgta
     3001 tgggttctca cggcgcattt gcctttcatg ccatctggat gcccaaggcc acccaagatc
     3061 agctgccctt gaccttgtca cgtctcactc ccaagcgcca tagaacacct ctcctggcgt
     3121 agccagttag actaaccaca gcagcgctgc tgtagttttc ttcctgttgc atacgctctc
     3181 acagctacac ctcagtgttc agtggtgtcc ctcctctaac tcagtgttga atcagactta
     3241 actgtaggag tgttcatgtc tcctcagttc ttcacaggct ctggaagagt caggcagcct
     3301 acagcataga attcaccaaa aacacccaag attctcgggg tggcattcag ttctctgtcc
     3361 cctgataacc atgctgccag ggctgctgca tcctgacatg cacccaggag aatagcacag
     3421 tttcatgcat atctgtaagc taaagatgga caagaatttt tttcatactt ttttcagaga
     3481 taccaaacca ttgtacacaa ttcagagaaa ttcattaact ttagagagcc acatatttct
     3541 gtatatccta aaacaaaaat gagcatgtgt cttctcttaa gctggtgtga ccatgaatct
     3601 gtggcttgac ctgtaatgct ctgagaaggc atgacatctg agctgattgc cagggaagca
     3661 agcccgaatg gcaggctgga ctcctgctgc tgagcagctg tgggcaagac cactgaaggc
     3721 actggagtca cttgagaaga tgttgtgtgg ctgatggtca gcagtcctgt tgagacacga
     3781 tggggtgggt ctatatcacc ttcataagga ccagtgggag tcagcatgga gaaccagagc
     3841 ggccctgctg gatgaggagc caatgtcaca ggcatagact agcagttgtc ctttctgtct
     3901 tagggacgtg gtgcttcaag tctgcccctc accttggctt cgatacaagt gggctttgct
     3961 ctggggcctg tccctggcgc tcaacagagc ctgcctctct gctgctgggt ggacctggaa
     4021 tctcatctac ctctgtagtc agtctctcca tgtgagaagc aagcttgagg ccagtgtcct
     4081 ccgacatgcc gtagcactta aagatttcca agggtccctg ggaaacgagc ccagggtcgc
     4141 tgcagcctgg agtttcacag ggattctaac ggggactggg gacctgactt ttgactttta
     4201 gccttaattc tagcccggca taatcatgta caatcttttg gaggtggcat caagtgtagg
     4261 ggcacccttt caggtgctaa cgctggtcaa aacagatttt aaaattaaaa ctttgtcata
     4321 tccatgcctc taaaaaaaaa aaaaaaaaaa aaaaaaaaaa
//
