LOCUS       NM_133879               2169 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus zinc finger and BTB domain containing 48 (Zbtb48),
            transcript variant 1, mRNA.
ACCESSION   NM_133879
VERSION     NM_133879.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2169)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2169)
  AUTHORS   Medeiros de Araujo,J.A., Barao,S., Mateos-White,I., Espinosa,A.,
            Costa,M.R., Gil-Sanz,C. and Muller,U.
  TITLE     ZBTB20 is crucial for the specification of a subset of callosal
            projection neurons and astrocytes in the mammalian neocortex
  JOURNAL   Development 148 (16) (2021)
   PUBMED   34351428
REFERENCE   3  (bases 1 to 2169)
  AUTHORS   Guo,G., Huss,M., Tong,G.Q., Wang,C., Li Sun,L., Clarke,N.D. and
            Robson,P.
  TITLE     Resolution of cell fate decisions revealed by single-cell gene
            expression analysis from zygote to blastocyst
  JOURNAL   Dev Cell 18 (4), 675-685 (2010)
   PUBMED   20412781
REFERENCE   4  (bases 1 to 2169)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   5  (bases 1 to 2169)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL611927.21.
            
            On Apr 10, 2020 this sequence version replaced NM_133879.2.
            
            Transcript Variant: This variant (1), as well as variant 2, encodes
            the functional protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AM161454.1, SRR13422600.1236163.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-70                AL611927.21        28994-29063         c
            71-742              AL611927.21        27839-28510         c
            743-984             AL611927.21        27229-27470         c
            985-1096            AL611927.21        24147-24258         c
            1097-1189           AL611927.21        23478-23570         c
            1190-1276           AL611927.21        22993-23079         c
            1277-1431           AL611927.21        22740-22894         c
            1432-1568           AL611927.21        22230-22366         c
            1569-1733           AL611927.21        21995-22159         c
            1734-1822           AL611927.21        21641-21729         c
            1823-2169           AL611927.21        21225-21571         c
FEATURES             Location/Qualifiers
     source          1..2169
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 82.83 cM"
     gene            1..2169
                     /gene="Zbtb48"
                     /gene_synonym="0610011D15Rik; Hkr3; TZAP"
                     /note="zinc finger and BTB domain containing 48"
                     /db_xref="GeneID:100090"
                     /db_xref="MGI:MGI:2140248"
     exon            1..70
                     /gene="Zbtb48"
                     /gene_synonym="0610011D15Rik; Hkr3; TZAP"
                     /inference="alignment:Splign:2.1.0"
     exon            71..742
                     /gene="Zbtb48"
                     /gene_synonym="0610011D15Rik; Hkr3; TZAP"
                     /inference="alignment:Splign:2.1.0"
     CDS             74..2119
                     /gene="Zbtb48"
                     /gene_synonym="0610011D15Rik; Hkr3; TZAP"
                     /note="GLI-Kruppel family member HKR3; zinc finger and BTB
                     domain-containing protein 48; GLI-Krueppel family member
                     HKR3; Krueppel-related zinc finger protein 3 homolog"
                     /codon_start=1
                     /product="telomere zinc finger-associated protein"
                     /protein_id="NP_598640.2"
                     /db_xref="CCDS:CCDS38982.1"
                     /db_xref="GeneID:100090"
                     /db_xref="MGI:MGI:2140248"
                     /translation="MDGSFVQHSVRVLQELNKQREKGQYCDATLDVGGLVFKAHWSVL
                     ACCSHFFQRIYGDGTGGSVVLPAGFAEIFGLLLDFFYTGHLALTSGNRDQVLLAAKEL
                     RVPEAVELCQSFQPQTSVGQAQSGLGQPASQDVKSHLKEPTDLDEEEVFRTLSLASVD
                     QEPRDTEQPQLGTPAQSTTAFLCGKLTQALKPSPSEDKESEDCKEPPRPFEAGGAPLQ
                     GESNEWEVVVQVEDDRDGDYVSEPETVLTRRKSKVIRKPCAAEPALGAGSLTAEPTDS
                     RKGAAVPVECPTCHKKFLSKYYLKVHNRKHTGEKPFECPKCGKCYFRKENLLEHEARN
                     CMNRSEQVFTCSVCQETFRRRMELRLHMVSHTGEMPYKCSSCSQQFMQKKDLQSHMIK
                     LHGAPKPHACPTCAKCFLSRTELQLHEAFKHRGEKLFVCEECGHRASSRNGLQMHIKA
                     KHRNERPYVCEFCSHAFTQKANLNMHLRTHTGEKPFQCHLCGKTFRTQASLDKHNRTH
                     TGERPFSCEFCEQRFTEKGPLLRHVASRHQEGRPHFCQICGKTFKAVEQLRVHVRRHK
                     GVRKFECTECGYKFTRQAHLRRHMEIHDRVENYNPRQRKLRNLIIEDEKMVVVALQPP
                     ADLEVGSAEVIVESLTQGGLASQLPSQRLCSEESFASPGVLEPSLIITAAVPEDCDT"
     exon            743..984
                     /gene="Zbtb48"
                     /gene_synonym="0610011D15Rik; Hkr3; TZAP"
                     /inference="alignment:Splign:2.1.0"
     exon            985..1096
                     /gene="Zbtb48"
                     /gene_synonym="0610011D15Rik; Hkr3; TZAP"
                     /inference="alignment:Splign:2.1.0"
     exon            1097..1189
                     /gene="Zbtb48"
                     /gene_synonym="0610011D15Rik; Hkr3; TZAP"
                     /inference="alignment:Splign:2.1.0"
     exon            1190..1276
                     /gene="Zbtb48"
                     /gene_synonym="0610011D15Rik; Hkr3; TZAP"
                     /inference="alignment:Splign:2.1.0"
     exon            1277..1431
                     /gene="Zbtb48"
                     /gene_synonym="0610011D15Rik; Hkr3; TZAP"
                     /inference="alignment:Splign:2.1.0"
     exon            1432..1568
                     /gene="Zbtb48"
                     /gene_synonym="0610011D15Rik; Hkr3; TZAP"
                     /inference="alignment:Splign:2.1.0"
     exon            1569..1733
                     /gene="Zbtb48"
                     /gene_synonym="0610011D15Rik; Hkr3; TZAP"
                     /inference="alignment:Splign:2.1.0"
     exon            1734..1822
                     /gene="Zbtb48"
                     /gene_synonym="0610011D15Rik; Hkr3; TZAP"
                     /inference="alignment:Splign:2.1.0"
     exon            1823..2169
                     /gene="Zbtb48"
                     /gene_synonym="0610011D15Rik; Hkr3; TZAP"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2147..2152
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zbtb48"
                     /gene_synonym="0610011D15Rik; Hkr3; TZAP"
                     /note="hexamer: AATAAA"
     polyA_site      2169
                     /gene="Zbtb48"
                     /gene_synonym="0610011D15Rik; Hkr3; TZAP"
                     /note="major polyA site"
ORIGIN      
        1 agtcttgtgg gcggtggaag tggtctaggc cggagcagtg aagccggtgt gagccgggag
       61 gaccggcggg attatggacg gttccttcgt gcagcacagc gtgagggttc tgcaggaact
      121 caacaagcag cgcgagaagg gccagtattg cgacgccaca ctggacgtgg ggggcctggt
      181 gttcaaggcg cactggagtg tcctggcgtg ttgcagccat ttcttccaga gaatctacgg
      241 ggatggcaca gggggcagcg ttgtcctccc agcgggcttt gctgagattt ttggcctcct
      301 gctggacttt ttctacactg gccacctcgc cctcacctca gggaacaggg atcaggtact
      361 cttggcagcc aaagagttga gggtgcctga ggctgtggag ctatgtcaga gcttccagcc
      421 ccaaacctca gtgggacagg cacagagtgg actgggtcaa cctgcctccc aggacgtgaa
      481 aagccacctg aaggagccga cagacttgga tgaggaggaa gttttcagga ctctgagcct
      541 ggcctccgtg gatcaggagc ccagagacac tgagcagccc cagctgggta cacctgctca
      601 gagcaccacg gccttcctct gtgggaaact cacgcaggct ttgaagcctt ctccctcaga
      661 ggacaaagag tctgaggact gcaaagagcc cccaaggccc ttcgaggctg gaggtgcccc
      721 gctgcagggc gagagcaatg agtgggaagt ggtggtccaa gtggaggacg acagggacgg
      781 tgattacgta tctgagcctg agactgtgct aaccagaagg aagtcaaaag tgattagaaa
      841 accctgtgca gccgagccag ccctgggtgc gggttctctc acagccgagc ccactgacag
      901 cagaaaaggt gcagccgttc cggtcgaatg tcccacatgt cacaaaaagt tcctcagcaa
      961 atattacctg aaagtccaca acaggaaaca cactggggag aaacccttcg agtgtcccaa
     1021 atgtgggaag tgttacttcc gcaaggagaa tctcttggaa catgaagcca ggaattgcat
     1081 gaaccgctca gaacaggtct tcacatgctc cgtatgccag gagaccttcc gacggaggat
     1141 ggagctgcgc ttgcacatgg tgtctcacac aggggagatg ccctacaagt gttcctcctg
     1201 ctcccagcag ttcatgcaga agaaagactt gcagagccac atgatcaagc tgcacggagc
     1261 ccctaaaccc cacgcatgcc ccacttgtgc caagtgcttc ctgtctagga cggagctaca
     1321 gctgcacgag gcttttaagc atcgtggaga aaagctcttt gtgtgtgagg aatgcgggca
     1381 ccgggcctcg agccgcaacg gactgcagat gcacatcaag gccaagcaca ggaatgaaag
     1441 gccttatgtc tgtgagttct gcagccatgc cttcacccag aaggccaacc tcaacatgca
     1501 cctgcgcaca cacaccggcg agaagccttt ccagtgccac ctctgtggga agaccttccg
     1561 cacccaagcc agtttggaca agcacaaccg cacccacacg ggcgagaggc ctttcagctg
     1621 tgaattctgt gagcagcgct tcactgagaa gggccccctt ctgaggcatg tggccagccg
     1681 ccatcaagag ggcaggcccc acttctgcca gatctgtggc aagaccttca aagctgtgga
     1741 acagttacga gtgcacgtca ggcgacacaa aggtgtgaga aagttcgagt gcaccgagtg
     1801 tggctacaag ttcacgcggc aggctcacct gcggaggcac atggagatcc acgacagagt
     1861 ggagaactac aatccccggc agcgcaagct ccggaacctc atcattgagg atgagaagat
     1921 ggtggtcgtg gctctccagc cccctgcaga cctggaggtg ggctctgctg aggtcattgt
     1981 ggagtccctg acccagggtg gccttgcctc ccaactccct agccagagac tgtgttcaga
     2041 ggagagcttt gctagccctg gcgtcctgga gccctctctc atcatcaccg ctgctgttcc
     2101 cgaggactgt gacacgtaga cccctgcccg gatggcccca ctgaccaata aacatgtgac
     2161 ttagcactt
//
