LOCUS       NM_198248               7208 bp    mRNA    linear   ROD 04-AUG-2023
DEFINITION  Mus musculus zinc finger and BTB domain containing 40 (Zbtb40),
            mRNA.
ACCESSION   NM_198248 XM_149534
VERSION     NM_198248.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7208)
  AUTHORS   Cui Y, Zhou M, He Q and He Z.
  TITLE     Zbtb40 Deficiency Leads to Morphological and Phenotypic
            Abnormalities of Spermatocytes and Spermatozoa and Causes Male
            Infertility
  JOURNAL   Cells 12 (9), 1264 (2023)
   PUBMED   37174664
  REMARK    GeneRIF: Zbtb40 Deficiency Leads to Morphological and Phenotypic
            Abnormalities of Spermatocytes and Spermatozoa and Causes Male
            Infertility.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7208)
  AUTHORS   Shi Z, Zhong Q, Chen Y and Luo X.
  TITLE     Long noncoding RNA ZBTB40-IT1 regulates bone mass by directing the
            differentiation of human bone marrow mesenchymal stromal cells via
            the microRNA-514a-3p/FOXO4 axis
  JOURNAL   Hum Cell 35 (5), 1408-1423 (2022)
   PUBMED   35676609
  REMARK    GeneRIF: Long noncoding RNA ZBTB40-IT1 regulates bone mass by
            directing the differentiation of human bone marrow mesenchymal
            stromal cells via the microRNA-514a-3p/FOXO4 axis.
REFERENCE   3  (bases 1 to 7208)
  AUTHORS   Medeiros de Araujo JA, Barao S, Mateos-White I, Espinosa A, Costa
            MR, Gil-Sanz C and Muller U.
  TITLE     ZBTB20 is crucial for the specification of a subset of callosal
            projection neurons and astrocytes in the mammalian neocortex
  JOURNAL   Development 148 (16) (2021)
   PUBMED   34351428
REFERENCE   4  (bases 1 to 7208)
  AUTHORS   Doolittle ML, Calabrese GM, Mesner LD, Godfrey DA, Maynard RD,
            Ackert-Bicknell CL and Farber CR.
  TITLE     Genetic analysis of osteoblast activity identifies Zbtb40 as a
            regulator of osteoblast activity and bone mass
  JOURNAL   PLoS Genet 16 (6), e1008805 (2020)
   PUBMED   32497039
  REMARK    GeneRIF: Genetic analysis of osteoblast activity identifies Zbtb40
            as a regulator of osteoblast activity and bone mass.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 7208)
  AUTHORS   Piao Y, Ko NT, Lim MK and Ko MS.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC059177.1.
            
            On Dec 17, 2003 this sequence version replaced XM_149534.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC059177.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..7208
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 69.05 cM"
     gene            1..7208
                     /gene="Zbtb40"
                     /gene_synonym="C230087D24; Gm571; mKIAA0478"
                     /note="zinc finger and BTB domain containing 40"
                     /db_xref="GeneID:230848"
                     /db_xref="MGI:MGI:2682254"
     exon            1..50
                     /gene="Zbtb40"
                     /gene_synonym="C230087D24; Gm571; mKIAA0478"
                     /inference="alignment:Splign:2.1.0"
     exon            51..794
                     /gene="Zbtb40"
                     /gene_synonym="C230087D24; Gm571; mKIAA0478"
                     /inference="alignment:Splign:2.1.0"
     CDS             98..3874
                     /gene="Zbtb40"
                     /gene_synonym="C230087D24; Gm571; mKIAA0478"
                     /codon_start=1
                     /product="zinc finger and BTB domain-containing protein
                     40"
                     /protein_id="NP_937891.1"
                     /db_xref="CCDS:CCDS18814.1"
                     /db_xref="GeneID:230848"
                     /db_xref="MGI:MGI:2682254"
                     /translation="MELPSYSQQLLLQLYALCKEQRFCDCTISVGNIYFRAHKPVLAA
                     ASLLFKTLLDSTDAISIDASVVSPEEFALLLEMTYTGKLPVGKHNFSKIISLADSLQM
                     FDVAVSCKNLLTNLVNCSVQGQVVRDVSVLSSEAGNKESEKPQVEALSSEGAEEPSSS
                     PEVSAVPAGPEKAKTQDVINIATQEINADPPVAQEVQVAAEITGATPHTAEVCSPSPV
                     GQIPSETKEVNTEAECETKQDQLTLLLEHESVFSDAALLTPDTLRRLAGCSEIEGPQK
                     ETIIECLTSEGGSSAFQRILDKVHDGSLDVQVALSLVRLYQESTPAEKVSQIQPEGSA
                     GEGKTLSVLLLEHKEDLIQCVTQLRPIVEFLETAKEEFLPDSEKRVIQSCCEGRTPKE
                     MIENLLHRVTEEKTLPAKSLVKLLQAVRTAFPNLDLLLDNLQKGAGSAGTTGLARVSC
                     ESEWTDEPRPVCIPADRVDGSSPSPDAYGAELLRKYHENLSEILIDNQVLLKVISRMQ
                     SLAPGDREVMQTLVKQGSGSGGFSSLMLAALERQTLSATAIWQLLLAVEETETRPLNL
                     LLEEVGKEPGAGAFFRAVTAPESTVLEAILRHSKLLREAIQQTAGCERLSSEEEHLAE
                     TVQEMLSISSETVSPEASLRAVLSKAMEKSVSASVVCHLLCSVHKSFPGLQPLMQELA
                     HVGFLTKESGEERWKVTDGLHPGAKDKVEEVAKATGEDCQANEQKEQGEPGPVPEQPE
                     KDTSASPDSAKKSFVCKACDKSFHFYCRLKVHMKRCRVAKSRQVQSEEGSETKGSEKG
                     LEKQQPDARGTGGEPDAPKKKKKRLPVTCDLCGREFAHASGMQYHKLTEHFDEKPFSC
                     EECGAKFAANSTLKNHLRLHTGDRPFMCKHCLMTFTQASALAYHTKKKHSEGKMYACQ
                     YCDAVFAQSIELSRHVRTHTGDKPYVCRDCGKGFRQANGLSIHLHTFHTDIEDPYDCK
                     KCRMSFSTLQDHRKHIHEVHAKEYHPCPTCGKIFSAPSMLERHMVTHVGGKPFSCGIC
                     NKAYQQLSGLWYHNRTHHPDVFAAQNHRSPKFSSLQCSSCDKTFSNTVEHKKHIKTEH
                     TDVKFHECDQCKELFPTPALLQVHVKCQHSGSQPFRCLYCAATFRFPGALQHHVTTEH
                     FKQSESTFPCELCGELFTSQAQLDSHLESEHPKVAGTESQAAASRMVQVIRAPEPAAP
                     AEQVITLEETQLAGSQVFVTLPDSQTSQNSSELVAVTVEDLLDGTVTLICGEAK"
     exon            795..928
                     /gene="Zbtb40"
                     /gene_synonym="C230087D24; Gm571; mKIAA0478"
                     /inference="alignment:Splign:2.1.0"
     exon            929..1091
                     /gene="Zbtb40"
                     /gene_synonym="C230087D24; Gm571; mKIAA0478"
                     /inference="alignment:Splign:2.1.0"
     exon            1092..1234
                     /gene="Zbtb40"
                     /gene_synonym="C230087D24; Gm571; mKIAA0478"
                     /inference="alignment:Splign:2.1.0"
     exon            1235..1427
                     /gene="Zbtb40"
                     /gene_synonym="C230087D24; Gm571; mKIAA0478"
                     /inference="alignment:Splign:2.1.0"
     exon            1428..1508
                     /gene="Zbtb40"
                     /gene_synonym="C230087D24; Gm571; mKIAA0478"
                     /inference="alignment:Splign:2.1.0"
     exon            1509..1645
                     /gene="Zbtb40"
                     /gene_synonym="C230087D24; Gm571; mKIAA0478"
                     /inference="alignment:Splign:2.1.0"
     exon            1646..1847
                     /gene="Zbtb40"
                     /gene_synonym="C230087D24; Gm571; mKIAA0478"
                     /inference="alignment:Splign:2.1.0"
     exon            1848..1981
                     /gene="Zbtb40"
                     /gene_synonym="C230087D24; Gm571; mKIAA0478"
                     /inference="alignment:Splign:2.1.0"
     exon            1982..2150
                     /gene="Zbtb40"
                     /gene_synonym="C230087D24; Gm571; mKIAA0478"
                     /inference="alignment:Splign:2.1.0"
     exon            2151..2612
                     /gene="Zbtb40"
                     /gene_synonym="C230087D24; Gm571; mKIAA0478"
                     /inference="alignment:Splign:2.1.0"
     exon            2613..2819
                     /gene="Zbtb40"
                     /gene_synonym="C230087D24; Gm571; mKIAA0478"
                     /inference="alignment:Splign:2.1.0"
     exon            2820..2984
                     /gene="Zbtb40"
                     /gene_synonym="C230087D24; Gm571; mKIAA0478"
                     /inference="alignment:Splign:2.1.0"
     exon            2985..3202
                     /gene="Zbtb40"
                     /gene_synonym="C230087D24; Gm571; mKIAA0478"
                     /inference="alignment:Splign:2.1.0"
     exon            3203..3365
                     /gene="Zbtb40"
                     /gene_synonym="C230087D24; Gm571; mKIAA0478"
                     /inference="alignment:Splign:2.1.0"
     exon            3366..3452
                     /gene="Zbtb40"
                     /gene_synonym="C230087D24; Gm571; mKIAA0478"
                     /inference="alignment:Splign:2.1.0"
     exon            3453..3679
                     /gene="Zbtb40"
                     /gene_synonym="C230087D24; Gm571; mKIAA0478"
                     /inference="alignment:Splign:2.1.0"
     exon            3680..7192
                     /gene="Zbtb40"
                     /gene_synonym="C230087D24; Gm571; mKIAA0478"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctcaatggcg ctgtcaataa agaacggcag tttgaatcgg tgctgagcag gtggagtctg
       61 aagggctaga ggaaggcggc aagggcagag ccacagcatg gaactcccca gctacagcca
      121 gcagctgctt ctgcagctct acgccctgtg caaggagcag cggttctgtg attgcaccat
      181 ttccgtcggc aacatctact tcagggccca caagccagtc ctggcagcag ccagcctcct
      241 gttcaaaacc ctgctggaca gcacagacgc catctccatc gatgcatccg tggtgagccc
      301 cgaagagttt gccctcttgc tagaaatgac atacaccggt aagctacctg tgggcaagca
      361 caacttctcc aagatcatct ccttagcaga tagcctgcag atgtttgacg tggccgttag
      421 ttgtaaaaac cttctgacca acctggtaaa ctgctctgtc caggggcagg tggtaagaga
      481 tgtctcagtg ctgtcctcag aggcagggaa caaggagtca gagaagccac aagtagaagc
      541 cctctcctct gaaggtgctg aggagccctc ttcttccccg gaagtttctg ccgtgccagc
      601 gggccctgag aaagccaaga cccaggacgt aatcaacata gctacccaag agataaatgc
      661 agaccctccc gttgcccaag aggttcaggt ggctgcagag atcacagggg cgactcctca
      721 cacagctgaa gtttgttccc cttcccctgt tggacaaatc ccaagtgaga cgaaagaagt
      781 caatacagaa gcagagtgcg agacaaagca ggaccaactg actctcctgc tagagcatga
      841 aagcgtcttc tcagatgcag ccttgctcac cccagacacc ctgagaagac tggcaggatg
      901 ctcagagatt gaagggcctc agaaggagac cataatagaa tgtctcacga gtgaaggagg
      961 cagttcagcg ttccagagaa ttctggacaa agtgcacgat gggagcctgg atgtgcaggt
     1021 ggctctgtct ctggtgagac tataccagga gtctacacct gcagagaaag tgtctcagat
     1081 tcaaccagaa gggagcgcag gagagggaaa gaccttgtct gttctgctac tggaacacaa
     1141 agaggacctg atccagtgtg taacacagct cagacctatt gtggagttcc tggaaacagc
     1201 caaggaggaa ttcctgccag attccgaaaa aagggtgatt cagagctgct gtgagggcag
     1261 aacacccaag gagatgatag agaatttgtt gcacagagtg actgaagaga agaccctgcc
     1321 tgccaagagt ctggtaaaac tcctccaggc tgtgaggaca gcattcccaa acctggacct
     1381 cctgctggac aatttgcaga aaggagcggg atcagccggc accacaggcc tggccagagt
     1441 ctcctgtgaa tcagaatgga cagatgagcc caggccagtg tgcattccag cagaccgcgt
     1501 ggatggatcc tcccctagcc ctgatgctta cggagctgag ctgttgagaa agtaccatga
     1561 gaacctgtct gagattctca tagacaacca ggtgctgctg aaggtgatct cacggatgca
     1621 aagcttagcc cctggagaca gagaggtcat gcagaccctc gtgaaacagg gctctggctc
     1681 gggtggcttc agttccctga tgttggcagc tctggaaagg cagactctct cagcaacggc
     1741 catttggcaa ctactgctag cagttgaaga gactgagacc cgcccactga acctgctctt
     1801 ggaggaagta ggaaaggagc ccggcgctgg ggctttcttc cgggcagtga ctgccccaga
     1861 gagcacagta ttggaagcca tcctgaggca cagcaagctg ctccgggaag ccatccagca
     1921 gacagcgggg tgtgagcgcc tttcttcaga ggaagaacac ctggcagaga ccgtgcaaga
     1981 gatgctgagc atatcctccg agacagtgag ccctgaagcc tccctgagag cggtgctgag
     2041 caaagccatg gagaaatctg tctcggcctc tgtggtctgt cacctcctct gcagtgtcca
     2101 caagtctttc cctggcctgc agcccctgat gcaggagttg gcacatgttg gtttccttac
     2161 caaggaaagc ggagaggaga ggtggaaggt gactgatggc cttcaccctg gagccaagga
     2221 caaagtggag gaagtggcca aggcaaccgg agaagactgc caggccaatg aacaaaagga
     2281 gcagggagag cctgggcccg tgccagagca accggagaaa gacacttctg cctccccaga
     2341 ctctgccaag aagagcttcg tctgcaaagc ctgtgataag agcttccatt tctactgccg
     2401 tctgaaggtg cacatgaagc gctgccgggt ggccaagagc aggcaggtgc agagcgagga
     2461 gggcagcgag accaagggct cggagaaggg gctggagaag cagcagccgg acgcccgcgg
     2521 cacaggtggg gagcccgatg cccccaagaa gaagaagaag cggctgccag tgacatgtga
     2581 cctctgcgga agagagtttg cccatgcctc aggcatgcag taccacaagc tgaccgagca
     2641 cttcgacgag aaacctttct cctgtgagga atgtggggcg aagtttgcag ccaactctac
     2701 cctgaagaac cacctgcgcc tgcacaccgg agaccgcccg ttcatgtgca agcattgcct
     2761 catgaccttc acgcaggcct ccgccctggc ttaccacacc aagaagaagc actcggaagg
     2821 gaaaatgtac gcgtgccagt actgtgacgc cgtgttcgcc cagtcgatcg agctatcccg
     2881 gcatgtgagg acccacaccg gggacaagcc atatgtctgt agggactgtg gaaagggctt
     2941 ccggcaagcc aacggcctct ccatccacct gcacaccttc cacacagaca tagaagaccc
     3001 ttatgactgc aagaaatgca ggatgagctt ctccacactg caggaccacc ggaagcacat
     3061 ccacgaggtg cacgccaagg agtaccaccc ctgccccacg tgcggcaaga tcttcagtgc
     3121 cccttccatg ctggagcggc acatggtgac ccacgtggga gggaagccct tcagctgtgg
     3181 gatctgcaac aaggcctacc agcaattgtc tggattgtgg taccacaatc ggacgcacca
     3241 cccagatgtg tttgctgctc agaaccatcg gtcacccaag ttctcatcac tgcagtgtag
     3301 ctcctgtgac aagacctttt ccaatactgt cgaacacaag aagcacatca aaacagaaca
     3361 cacagatgtg aagttccatg agtgtgacca gtgcaaggag ctcttcccca cacctgctct
     3421 gctccaggtt cacgtcaagt gccagcattc agggtcgcag ccattccggt gcttgtactg
     3481 tgcagccacc ttccgcttcc cgggagccct gcagcaccac gtcaccacag agcactttaa
     3541 gcagtcggaa agcaccttcc cctgcgagct ctgtggcgag ctcttcacct cccaggccca
     3601 gcttgatagc cacttggagt ctgagcaccc aaaggtggca ggcactgagt cccaggcagc
     3661 tgcctctcgc atggtgcagg tgatccgagc tccggagcca gcggccccgg ccgagcaggt
     3721 gatcacgttg gaggagacgc agctcgctgg ctcgcaggtg tttgtgacct tgccagattc
     3781 acagacctct cagaacagct ccgagcttgt ggcagtgacg gtggaggatt tgctggatgg
     3841 tactgtcaca ttgatctgtg gtgaggccaa gtgagtggct tccttcagta gaggagcccg
     3901 tgctgtacca gcaaggatgc tctctgcctg cctctgctct agctgctcgg ctgagctcca
     3961 ccctggtgct ctcacttgaa aaacagaggc tttgtcgttc tcataggatc cacagtgtct
     4021 gagctatcca cgctgacacc aatactaccg ccctgtgtgg tggagcctca atcctccagg
     4081 cttcagctca tgcctggact ccacccaccc cagggaagtc tggcttctgg aatcagagtc
     4141 tgggggaatc agagtggagg ggagctggta gccaggatgg ccaaggagat acagcatgct
     4201 ggctgccctc aggagcagga gagttacctg agtctgagcc agcagaaggc cacagacacc
     4261 gccagtgcct ctgccaggga agcacccaca cagcctctag ggactcctgc gtggcagcct
     4321 gtcctccctg gcccctgctc aggttcccct tggaggctgt aagacaggtg gccatgttaa
     4381 cagtgcaggc attggcatcc ctgatcctcc ctgctctgtc tttcccaaaa cacagcttca
     4441 gagcattgcc actggggggg cagcttcatg tgaggccatc ctgctgcctc tgccttgctg
     4501 ggtgttcatt gcattcccat atcagaacct ccctgtgagg ctctggcctg ccacaccttc
     4561 aagctaatca aggctgaagc atcccagcct ggagacctct tgctgacttc ctctgtacca
     4621 tgtggtagtc taatgaagca gctcctgggg gcaggcctgt gcctgcatgt gacggattag
     4681 aggcatctga ggtggcttct gcttctcccg tggccggccc acatgcctgg tgcatggcct
     4741 gctccctggg atccccctgg ctgcatgctt actgcagcgc catgctcctt tcaagtctga
     4801 gtgtcacaga gccttttatc ttcagttcct gacacacagt ctggtaattg atggctcgtg
     4861 gaatccggtt ggaagtgcaa ttagatggat gttggttcct actgctcgga gagaagggct
     4921 tgcatctagc ttgcttttct agaagcccaa agagaggagt gggttatcac agtatttgcc
     4981 catcaggccg ggctccctgt cacctggtgt ggctggttac ctacagaggg gatgccctga
     5041 tttgacactc acctttaagc cacctgctct cagagataag cccacacctt cctgccaagt
     5101 gcagctcgca gaagcatgtg cagagaggga gggtctcttc tgatcatggc ggagatgcat
     5161 cgccaccatg ccttggcggg ctcacaggga gacaggcggt agcagcttaa accgcagcag
     5221 tgttcaaggc ctgctgccct ttggcctcag cttggcacaa gacagcactg gtgagtttct
     5281 attccagtga tggccagcct ctcccagtca gccccaccct cctcattgca tatgcaaatc
     5341 gtttgaactc atcagctagg gaatctcccc tttctaaaag taaatgtttt tcaaagcaag
     5401 tcagcctcag aagccaaaca ctgaccagaa gatggtgctc gagcaccgag acttcgcctc
     5461 cctgtttctt cactgcggcc ctagcctgct ggctttcaga ccgcgcctgc cagccgacca
     5521 ggggagctct cgatctgtaa gtggagaggt ggttcctcag tccatcgtcc aggcttctgt
     5581 caggaacagc acctcacaag ctgtggagga cttaggaact gtagtgtcac caacaaagtc
     5641 ttttcccagc aaaaggcaaa cctcacagag gtcctgagag agaaagtctc taaatacaaa
     5701 gagctgtaag gtagaaacct gagtgtctga gaaacacagt ctcgttttcc tggaacctgg
     5761 gtggtgtgct acctaccttc agtcaccaga ccgtagttgg ctgcagaaag ccttagggca
     5821 ggttggctgg ctgcccatcc ttggatgccc agctctgtaa tgcacactgc tggaggcaca
     5881 gcagtgctgg gtctggagta tggagaattc ctgtcctcaa tgagctctgt gctggtgact
     5941 cgcggcctct gccccagctg cctgactttt tacagtggct ctgaagaagg tgaaaaatct
     6001 ccatctgctg ccccagagac ctgccatgtg ggcctccgtg gtccacattg cttttgcaat
     6061 ggaactgtgg ctccatttgc ttcaacctca tgaatactac ctgcctagcc cgtgggcagg
     6121 agctagagga gcctccaggt cccttggaat ttgtgtattt aagcaacggg gccccagtct
     6181 tccctaaggc tcctgaccca gccaccaaag aggggaaggc gatgccaagc tggagtctgg
     6241 ttggcccgtc gctggtgtat ggactgagca ggtgagattt gctgtccaca tgcatgagca
     6301 gagccgaggc gagcgtggca gataaaggtc tttctcagct gttttatcag gatgggctct
     6361 actgtcttct aagctgtgtg tcagaaaagc tttgagttct gtcagcatcc aagcctgctg
     6421 tactgtaagt tctgggcctg tgtgttgtac tggccattct acagaagcct ccagcccatg
     6481 ctgaccacag gagatacctc agccttgtcc ctagtgcctg agcactgatg gttaggaccg
     6541 agatgaggga cagatgccaa atgaggggga aagatctctg tcgtcctgag gatggaaggg
     6601 tgtgccttta aatttcttgt gcctgagaac ctgtactgac aaaggatgga gaccctgacg
     6661 gccccactta gagtgggcag tgcttgccag gaacagaagt gtttcttctg gaactagaaa
     6721 gttggccagg ggtggagatg gcattggttt gttctagtca gctctcccac cccagctttg
     6781 ttcttccggg tcccgtctgt cccagcagac acttggaaga aattgagagt aagagactta
     6841 gggctgaggg agtcaaagga ggttcatagt tttgttgctg tggaaacctt ggggcactga
     6901 ggacttatac taaaactcag aaactcaaac ctactccagt ctaactgggc ctataaagaa
     6961 gaggagagtg tgagttcttt ggggactgtg ttgttgagga aatcgttcct tgagcaattt
     7021 tacattgcct ccaaattgtg aagctggccg cggtttccct gcccaaggcc gccgctgctc
     7081 gtttccaccc agggccagga cagccagccc cgtgagatgt gaaaactgat tgcaaactag
     7141 agctgctcga catgcactgt ggagagaaat aaagtctgta cttaggaagc aaaaaaaaaa
     7201 aaaaaaaa
//
