LOCUS       NM_029348               7824 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Mus musculus zinc finger and BTB domain containing 4 (Zbtb4),
            transcript variant 1, mRNA.
ACCESSION   NM_029348 XM_894801 XM_992938
VERSION     NM_029348.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7824)
  AUTHORS   Wu,H., Wang,Q., Liao,Y. and Wang,S.
  TITLE     MSC-derived exosomes deliver ZBTB4 to mediate transcriptional
            repression of ITIH3 in astrocytes in spinal cord injury
  JOURNAL   Brain Res Bull 212, 110954 (2024)
   PUBMED   38641154
  REMARK    GeneRIF: MSC-derived exosomes deliver ZBTB4 to mediate
            transcriptional repression of ITIH3 in astrocytes in spinal cord
            injury.
REFERENCE   2  (bases 1 to 7824)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 7824)
  AUTHORS   Roy,T.A., Bubier,J.A., Dickson,P.E., Wilcox,T.D., Ndukum,J.,
            Clark,J.W., Sukoff Rizzo,S.J., Crabbe,J.C., Denegre,J.M.,
            Svenson,K.L., Braun,R.E., Kumar,V., Murray,S.A., White,J.K.,
            Philip,V.M. and Chesler,E.J.
  TITLE     Discovery and validation of genes driving drug-intake and related
            behavioral traits in mice
  JOURNAL   Genes Brain Behav 23 (1), e12875 (2024)
   PUBMED   38164795
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   4  (bases 1 to 7824)
  AUTHORS   Medeiros de Araujo,J.A., Barao,S., Mateos-White,I., Espinosa,A.,
            Costa,M.R., Gil-Sanz,C. and Muller,U.
  TITLE     ZBTB20 is crucial for the specification of a subset of callosal
            projection neurons and astrocytes in the mammalian neocortex
  JOURNAL   Development 148 (16) (2021)
   PUBMED   34351428
REFERENCE   5  (bases 1 to 7824)
  AUTHORS   Sundberg,J.P., Dadras,S.S., Silva,K.A., Kennedy,V.E., Garland,G.,
            Murray,S.A., Sundberg,B.A., Schofield,P.N. and Pratt,C.H.
  TITLE     Systematic screening for skin, hair, and nail abnormalities in a
            large-scale knockout mouse program
  JOURNAL   PLoS One 12 (7), e0180682 (2017)
   PUBMED   28700664
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 7824)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   7  (bases 1 to 7824)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   8  (bases 1 to 7824)
  AUTHORS   Barrett,C.W., Smith,J.J., Lu,L.C., Markham,N., Stengel,K.R.,
            Short,S.P., Zhang,B., Hunt,A.A., Fingleton,B.M., Carnahan,R.H.,
            Engel,M.E., Chen,X., Beauchamp,R.D., Wilson,K.T., Hiebert,S.W.,
            Reynolds,A.B. and Williams,C.S.
  TITLE     Kaiso directs the transcriptional corepressor MTG16 to the Kaiso
            binding site in target promoters
  JOURNAL   PLoS One 7 (12), e51205 (2012)
   PUBMED   23251453
REFERENCE   9  (bases 1 to 7824)
  AUTHORS   Tamplin,O.J., Cox,B.J. and Rossant,J.
  TITLE     Integrated microarray and ChIP analysis identifies multiple Foxa2
            dependent target genes in the notochord
  JOURNAL   Dev Biol 360 (2), 415-425 (2011)
   PUBMED   22008794
REFERENCE   10 (bases 1 to 7824)
  AUTHORS   Okazaki,N., F-Kikuno,R., Ohara,R., Inamoto,S., Koseki,H.,
            Hiraoka,S., Saga,Y., Seino,S., Nishimura,M., Kaisho,T., Hoshino,K.,
            Kitamura,H., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: IV. The complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (3), 205-218 (2004)
   PUBMED   15368895
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ106077.1, AK147212.1, CA325272.1 and BE943927.1.
            
            On Nov 28, 2007 this sequence version replaced NM_029348.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK147212.1, SRR10223971.11622.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-47                CJ106077.1         2-48
            48-2012             AK147212.1         2-1966
            2013-2391           CA325272.1         78-456
            2392-7821           AK147212.1         2346-7775
            7822-7824           BE943927.1         15-17               c
FEATURES             Location/Qualifiers
     source          1..7824
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 42.87 cM"
     gene            1..7824
                     /gene="Zbtb4"
                     /gene_synonym="2310026P19Rik; 9230111I22Rik; mKIAA1538"
                     /note="zinc finger and BTB domain containing 4"
                     /db_xref="GeneID:75580"
                     /db_xref="MGI:MGI:1922830"
     exon            1..174
                     /gene="Zbtb4"
                     /gene_synonym="2310026P19Rik; 9230111I22Rik; mKIAA1538"
                     /inference="alignment:Splign:2.1.0"
     exon            175..241
                     /gene="Zbtb4"
                     /gene_synonym="2310026P19Rik; 9230111I22Rik; mKIAA1538"
                     /inference="alignment:Splign:2.1.0"
     exon            242..1269
                     /gene="Zbtb4"
                     /gene_synonym="2310026P19Rik; 9230111I22Rik; mKIAA1538"
                     /inference="alignment:Splign:2.1.0"
     CDS             251..3199
                     /gene="Zbtb4"
                     /gene_synonym="2310026P19Rik; 9230111I22Rik; mKIAA1538"
                     /codon_start=1
                     /product="zinc finger and BTB domain-containing protein 4"
                     /protein_id="NP_083624.2"
                     /db_xref="CCDS:CCDS36197.2"
                     /db_xref="GeneID:75580"
                     /db_xref="MGI:MGI:1922830"
                     /translation="MPPPAEVTDPSHAPAVLHQLNEQRLRGLFCDVTLIAGDTKFPAH
                     RSVLAASSPFFREALLASAPLPLPPVTGGSAPSPATTTAASSSSSSPPPASPHSSSPP
                     RVLELPGVPAAAFSDVLNFIYSARLALPGGGGDGAAVAEIGALGRRLGISRLQGLGEG
                     GDTWVPPAPTSMVTSDPTEDGLGAGPRTDGEWVGDKAEALTPDSQPRRPFPCPRCGKS
                     FIHPKRLQTHEAQCRRGSNTRGSAGLGPGVSGSGGPAGVDASALPQPVGFRDGPEHVV
                     KVVGGHVLYVCAACERSYVTLSSLKRHSNVHSWRRKYPCRYCEKVFALAEYRTKHEVW
                     HTGERRYQCIFCWDTFVTYYNLKTHQRAFHGISPGLLASEKTPNGGYKPRLNTLKLYR
                     LLPMRAAKRPYKTYSQGAPEAPLSPSLHTPAPAAMPASPQPLPPPAPEPGPPPSVITF
                     AHPAPSVIVHGSSSSGAAGGGPAGTGGSQAASVITYTTPPRPPKKREYPPPPPEPTAT
                     PTSPASTAVSPATAAGPATATEEAKGRNLRAGRTLTYTAKPVGGLSGSGGSPTGTGRG
                     SSQLQAPPPLCQITVRIGEEAIVKRRISETDLRPGELSGEEVEESEEEEEEEEEEDQE
                     EQEESKAGGEDQLWRPYYSYKPKRKAGATAGGASGVSGLPRGRRPPRWRQKLERRGWE
                     ETPSVEGPGGRGRGERRHRCGDCAQAFATVRKLRKHQEAHSGGSHTSRTGRRSSTRFT
                     CPHCAKVCKTAAALNRHGQRHAVERPGGTPTPVIAYSKGSIGTRPTDVKEEAPQEMQV
                     SSSSGEAGSGSAAAAEASESASLQDPVISGGEEPPVAGGGSYVYPPVQEFPLALIGGS
                     REPSAGKGKPGNEGSLGASEGDRMEGMGTAKVTFYPEPYPLVYGPQLLAAYPYNFSNL
                     AALPVALNMVLPDEKGGGALPFLPGVFGYAVNPQAAPPTPPPPLPLPVSPKGIGGMTG
                     VERTQKGDVG"
     exon            1270..7824
                     /gene="Zbtb4"
                     /gene_synonym="2310026P19Rik; 9230111I22Rik; mKIAA1538"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5726..5731
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zbtb4"
                     /gene_synonym="2310026P19Rik; 9230111I22Rik; mKIAA1538"
                     /note="hexamer: AATAAA"
     polyA_site      5748
                     /gene="Zbtb4"
                     /gene_synonym="2310026P19Rik; 9230111I22Rik; mKIAA1538"
                     /note="major polyA site"
     polyA_site      6523
                     /gene="Zbtb4"
                     /gene_synonym="2310026P19Rik; 9230111I22Rik; mKIAA1538"
     regulatory      7315..7320
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zbtb4"
                     /gene_synonym="2310026P19Rik; 9230111I22Rik; mKIAA1538"
                     /note="hexamer: AATAAA"
     polyA_site      7334
                     /gene="Zbtb4"
                     /gene_synonym="2310026P19Rik; 9230111I22Rik; mKIAA1538"
     regulatory      7798..7803
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zbtb4"
                     /gene_synonym="2310026P19Rik; 9230111I22Rik; mKIAA1538"
                     /note="hexamer: AATAAA"
     polyA_site      7824
                     /gene="Zbtb4"
                     /gene_synonym="2310026P19Rik; 9230111I22Rik; mKIAA1538"
ORIGIN      
        1 gatgatgtca gcggcggcgg cggcggcggt ggggctgggc cggggccggg cgctgggggg
       61 ggccggggcc ggggccggag ccggagccgg agctggagga gagcgaaacc caagcggccg
      121 gggctggcca cggtgatgag ccgggcctgg cagacgcggc gccatcgcag tcagaaggaa
      181 aaggccaggc tggagggact tgctgagcca cgacgcttct ccatgttggc tatgctctca
      241 ggctggcatc atgccacccc ctgcagaggt gacggaccca tcccatgccc cagctgtcct
      301 gcatcagctc aatgagcagc ggctccgtgg cctcttctgt gacgtcaccc tcatagctgg
      361 agacaccaag ttccctgctc accgcagtgt cctggccgcc tctagtccct tcttcagaga
      421 agccctacta gcttcagccc cactgcccct tccaccagtt actggcggct cagcccccag
      481 ccccgcaacc accacagctg cctcctcttc gtcctcctct ccccctccag cctctcctca
      541 ctcttcatct cctccccggg tgctagagct gcccggggtc ccagcagctg ccttctccga
      601 tgtcctcaac ttcatctata gtgcccggct tgcactccct ggcggtggtg gggatggggc
      661 agctgtggca gagattggag ctctgggccg gaggctgggt atctcccgtc tacagggcct
      721 gggggaagga ggtgatactt gggtaccacc tgccccaact tccatggtca cctcagatcc
      781 tactgaggat ggtttggggg cagggcctag aacagatgga gagtgggtgg gtgacaaagc
      841 tgaggccctg actcctgact cccagccccg gcggcccttt ccttgccctc gatgtggaaa
      901 aagcttcatc catcccaagc gactacagac ccacgaggct cagtgtcgac gagggtccaa
      961 cactcggggg tctgcagggc tggggcctgg agtctctggc tctgggggtc ctgcaggagt
     1021 ggatgcctct gccctgccac aaccagtggg cttcagagat ggccctgagc atgtggtgaa
     1081 ggttgtgggc ggccacgtgc tctatgtgtg tgcggcctgt gagcgttcct acgtgaccct
     1141 gtccagcctg aagcggcaca gcaatgtaca ctcgtggcgg aggaagtacc cctgccgcta
     1201 ctgtgagaag gtgtttgccc tggctgagta ccgcaccaag cacgaggtgt ggcacactgg
     1261 ggagcgcagg taccagtgca tcttctgctg ggacaccttt gtcacctatt ataacctgaa
     1321 gacccaccag cgagccttcc atggcattag ccctggcctc ctagccagtg agaagacacc
     1381 caatggaggc tacaaaccca ggcttaatac cctcaagctg taccgcctgc tccctatgcg
     1441 ggcggccaag cggccctaca agacctacag tcagggagcc cctgaggccc ctctttctcc
     1501 aagcctccac acaccggccc ccgcggcaat gccagccagc ccccaacccc tacccccacc
     1561 cgccccagag cctggtcctc ccccctctgt catcaccttt gctcatccgg ctccctctgt
     1621 cattgtccac gggagcagta gtagtggtgc agccgggggc ggaccagccg gcacaggagg
     1681 gtcccaagct gcctcagtca tcacttatac gactccccca agacccccca agaaacgaga
     1741 gtacccacct cctccccctg agcctacagc aacacccacc agcccagcct ccaccgccgt
     1801 cagcccagcc acagctgcag ggccagccac agccacagag gaggccaagg gccggaatct
     1861 gcgggctggg aggactctga cttacacagc caaacccgtg ggtgggttga gtgggagtgg
     1921 gggttccccc acagggactg gccgaggctc ttctcagctt caggctccac ctccactgtg
     1981 tcagatcact gtgcgaattg gggaagaggc cattgtcaag cgccgcatct cagaaactga
     2041 cctgcgtcct ggagagctga gtggagagga agtagaggag agcgaggaag aggaggagga
     2101 agaggaggag gaggaccagg aggaacaaga ggaatcgaag gctggagggg aagatcagct
     2161 ttggagaccc tactattcat acaagcctaa gcgcaaggct ggagctactg ccggcggggc
     2221 cagcggggtc agtggactgc cccgaggacg aagaccacca cgctggaggc aaaagctgga
     2281 acgaaggggc tgggaggaga ccccatcagt ggagggccca ggaggacgag gacgtggtga
     2341 gcgtaggcac cgttgtgggg actgtgccca ggcctttgcc actgtgagga agctgagaaa
     2401 gcaccaggaa gcccatagtg gaggctccca cacctccagg actgggagga ggtcttccac
     2461 ccgcttcacc tgtccccact gtgccaaggt gtgcaagacg gcagctgccc tgaaccgaca
     2521 tgggcaaagg catgctgtgg aacggcccgg gggcactccc acacctgtca ttgcctattc
     2581 caaaggaagc attggcacca ggcccactga cgtcaaggag gaggcccccc aggagatgca
     2641 agtgtcctct tccagtgggg aggcaggcag tggtagcgct gccgctgctg aagcttctga
     2701 gtctgcctca ctccaggacc cggtcatctc tgggggtgag gagcctccag tagcaggtgg
     2761 gggcagctat gtatacccac ctgtgcagga atttcccctg gccctgatag gaggcagccg
     2821 ggagcccagt gccggcaaag gaaaacctgg gaatgagggt tccttgggag cttctgaggg
     2881 tgaccggatg gaggggatgg ggactgccaa agtcaccttc taccctgagc cctacccact
     2941 tgtctatggc ccccagctcc ttgctgccta cccttacaac ttcagcaact tggctgctct
     3001 cccagttgct ctcaacatgg tcctacctga cgaaaaaggt ggtggggccc ttcccttcct
     3061 accaggggtc tttggctacg cagtgaatcc tcaagcggcg ccacccactc cccctccccc
     3121 tctccctctg ccagtttccc ctaagggaat agggggaatg acaggggtag agagaaccca
     3181 gaagggggat gtggggtgag caacaaggcc aggtccccct cttaccagat gccaccctcc
     3241 ccgagtcccc tccccccact ctcagctccc tggcctccct gccctttggg agccccatca
     3301 cactcttgtg cagggatttg ggggcccctg gagctcagga gtcaggctgc tttgtgtgat
     3361 tgtagtttcc ccattccctg agaagggagt tttggtggtt cctctctgtc ttctccaggg
     3421 aatggcccct gtgaggggaa gagccagctc ccatccctca tccagccctt ggggcaactg
     3481 agcaatatac ttatctgagt ctctacttac agcccccacc agctctgaat gtctaacctg
     3541 ctcccctgat ctgtaagcct agggggaacc atctctcacc caacgatgcc tgctcattct
     3601 gacgctgtct ctaagacctt cttccccaga ggcttcctag cacattccat cctttgtggc
     3661 ccaaggcctg gaccagacca ttgtgatatc caacccacca gcctggaagc atggcttttg
     3721 gattccgttc ttcccaaggg tgggtttccc tgtccttgtt tctttcatat taagacgcca
     3781 tgccttcctt ggcttccatg cctttggatc ttccatattc cttcctgtgc tcctagactt
     3841 ggagatggcc taacccattt caggtcaaaa ggaggtggga ggtgtcctgt ggctaagcac
     3901 tttctcaata cagggcaggg aaatcgtggg ccctaccttt acccccacgt ccagtgaccc
     3961 cagattcttc caagacaaaa gaggtgaata gatcataact cttctggcct ttatatgtgg
     4021 cttctttggg gctaacctaa ctttgagcac caggtatgaa gcactccata gagaatggag
     4081 aagatactct actttctccc tgacaacccc ttactagggc ttctcctaga ttagaccaaa
     4141 tagccagata aatggatggg gtttgatgtg tgggtaagcc caggatttga acatcacctc
     4201 catctttacc tttatccctt ctctgatgtc actgtcctca ccgatcactc cagatggttt
     4261 caaaggaacc atctttctct tctggtgggc tttggggtat ccccaccaac tttgcctcca
     4321 aaatagcacc ttatacccca tctttgactc agtcccccac acccaaagat cccagcctag
     4381 gaatggggtg cagggatttt aaatagtccc taatccctaa tttgcactag ttaaccctgg
     4441 tcaggggacc tatgtttcct tccagtaggg actatagaca aatgtttgtt cttaattccc
     4501 tttgaaaaat ggggcctccc tgatgtgtga ttagatggat atttccaata tacccatctc
     4561 ccctccccca caaagaaaga accagctcac aaagggagag ccagtttggg caagcaaatt
     4621 tgatgtggga gttagaggag tatgacttca aaaggagaaa gactgtttta accaaatgac
     4681 agtctttctc tcagctactg ttttctgggg ccaagatggc tgccctctga cctgctgtgg
     4741 agagggcaag atcatggctt ttggagggag gtgagtttgg gaaggccagg agcatcctcc
     4801 tgccccctcc tagcctccaa gtatatagaa agggggaggt ttttgacagg cttcctgaat
     4861 gttaaccacg gagggggtca ctccacccct cctctgtctc tttgcacttt tcttggtctt
     4921 ggctacagcc tgagtgaaga atttcctact gaatgtacca agttccagtt tttaagggtt
     4981 tggaaaaagt ttcaaacagg gaaaaatgga gagaaaaaaa aagaaaaaga aaaaaaatca
     5041 ctaaaaactc ccgtaaatct tgtttctggc actttagaaa aactgcaaaa aatacataat
     5101 aaagaataca tatatatata tctacacaca aattatatat ataaatatat ctatatatac
     5161 agcggaacca caagagagac tgaggaaggc ctgaaggcag ggggcagaca ggggtccctc
     5221 ctaccctcca ctgccctcct ctgaggaagt catgagagaa ggggtaaaaa atggtctggg
     5281 gaatttgaat ttcagaatag atcaaaattc taccttttgg aagaattgag attcttatgt
     5341 gggctttttt ttgttgtcgt tttttgtttt taataagggt aaagagaata gcttccagaa
     5401 tttagcaaca aatagttgtg gcaaagcaga aacttaaaaa tatgtatttg agatggaagg
     5461 tctcgatatc atgagtttca ggtgttggaa gtttgggatt tcgcaatttt gtcatttgaa
     5521 ggtgatcaag tcttgtcagt ttgtgccctc tttccccatg tgacctggga agaagggaga
     5581 aagtgggaag ccactggttc tgtgccacag cacgcaagat ttagaatttt acagactcta
     5641 gctctatatg tagtgaggac ccagatttag agaatctgac cactatttat ctccagattt
     5701 gtgtgtgttt ccaattctct aggccaataa atcaacaaga caaatgaact atgctcacag
     5761 cgggatgcca gatgcgatca tttgtgtgac tgggggtagg gggcaggcat ttgttgtctt
     5821 tgcttggcag ggatcctgag acctgtagcc tactcctgac tccaggtgct tcactgtagt
     5881 tgtctagccc ctaggctgca gctcacttct atctgacctc tctacacaga gatgctaact
     5941 ctggagctgg ggatgtagct cagtcggtag agagagggct tgagtagaat gcgggtgtgt
     6001 ttctcagctc aacaagatgg cacacaccta taaaacaagc gcttgggagg tgaaggttaa
     6061 gggtcatctt cagctacaca tagagttcca tagccccttt ctcacaaggt cccttcttaa
     6121 aaatgcagtg ctcccctgcc cccaccttta gaagcaccct taagtgctgt gttcaagatt
     6181 tctatgtccc agaataacct ttgccttaag ccaggtgcag agattgcatc attgccataa
     6241 gagctcctta ctccactcct gtctccttgg cttcatcttg cctgctgggt ctctttatgg
     6301 aggaatagct gggagcacga gtaaggctgg acaggtagat gagatcttgt ctggtttgag
     6361 tatcctgacc agagtgggtt gcgactcata agccctggca agttgctgtc aacagccgca
     6421 tctggtctct cgtcactata gctttctaaa tgttttcaag agaagccaaa aaacccaaat
     6481 gtctgtaagg tacacaaact ttaaaggtac caagcttcaa ctactttttt tcctttgagt
     6541 gttttgcttg catgtaggtc tgtgtaccac acatatacgg tgccagagga ggtcagaaag
     6601 agggtattcg atccactggg ggctggagtt gcacatgtgg gtgataggaa tcaaatcctg
     6661 aagaagagca gccaatgttc ctaacctcgg aatcatctct ctccagtccc taatccacat
     6721 ttaagatatc tttaatccta gcattcatga ggcagaagca agtggagttt gaggccaacc
     6781 tggtctacac aacaagctcc aggctagcca tggttacaga gcgagaccat gtctcgaggc
     6841 tgtgtaccgt agtgagttaa aggccaggtt ggacaactta ctaagactct gtttctaaaa
     6901 caaaaaccag gcttggtgag atgtgtctat aatcccagtt cttgaaagaa gcagatggat
     6961 caggagttta agtggttctt agctctgtag tgagttcagc caacctggac tgtatgagac
     7021 cctgtctcaa aacaaaacaa aaattaaagc tgcactagtg gtgaaaaact gtgaccccag
     7081 catttgagag ggtaaggcaa aagggttgct gagagttcaa gaccagcctg gactatatca
     7141 agactgtctt aaacaacagt aacaaaacca tgaagtcaaa aatgaaggaa aaataaggtc
     7201 tgttaaatag ctcagaggta gatgacttgc ctactgtttg caattctggg ttcaattcca
     7261 actactctaa aaacaaacca ataaatactg tacagcccaa ggacataggc aaaaaataaa
     7321 acaaaacaaa aaaacccaag ccaaaaaaaa aaatgcacct gtttgaaagc tctgatatat
     7381 actgttagga attctctatg ggcacatact actacgtgct ccattttaca gatataacaa
     7441 cagatagtga gtagtttagt ggtttgtgtg ccagagctag cacttgaata aggttgtgtg
     7501 tgagacaagg tctcattcta taacctcgac tgggtgaaac ccacagcagt cctgcctcag
     7561 ccttccaacg ctggggttct aagtatggga cactatgcct ggtttgaatg agatctctca
     7621 atatgtagca gaggttggcc ttgaactcat agcaatcctc ctgcctctgt cttccaagtt
     7681 ctgagattac aggcattcac caccactccc cccctccccc ttttttaaat gtttattgca
     7741 aatgctgact tttagaaata accttttttc actctaaagg tggtaatcat tgcaaaaaat
     7801 aaattttaga aagttaaaaa taga
//
