LOCUS       NM_001085507            6604 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus zinc finger and BTB domain containing 34 (Zbtb34),
            transcript variant 1, mRNA.
ACCESSION   NM_001085507 XM_140881 XM_992685
VERSION     NM_001085507.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6604)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 6604)
  AUTHORS   Medeiros de Araujo,J.A., Barao,S., Mateos-White,I., Espinosa,A.,
            Costa,M.R., Gil-Sanz,C. and Muller,U.
  TITLE     ZBTB20 is crucial for the specification of a subset of callosal
            projection neurons and astrocytes in the mammalian neocortex
  JOURNAL   Development 148 (16) (2021)
   PUBMED   34351428
REFERENCE   3  (bases 1 to 6604)
  AUTHORS   Kirchhof,P., Kahr,P.C., Kaese,S., Piccini,I., Vokshi,I.,
            Scheld,H.H., Rotering,H., Fortmueller,L., Laakmann,S., Verheule,S.,
            Schotten,U., Fabritz,L. and Brown,N.A.
  TITLE     PITX2c is expressed in the adult left atrium, and reducing Pitx2c
            expression promotes atrial fibrillation inducibility and complex
            changes in gene expression
  JOURNAL   Circ Cardiovasc Genet 4 (2), 123-133 (2011)
   PUBMED   21282332
REFERENCE   4  (bases 1 to 6604)
  AUTHORS   Okazaki,N., F-Kikuno,R., Ohara,R., Inamoto,S., Koseki,H.,
            Hiraoka,S., Saga,Y., Seino,S., Nishimura,M., Kaisho,T., Hoshino,K.,
            Kitamura,H., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: IV. The complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (3), 205-218 (2004)
   PUBMED   15368895
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL928955.17.
            
            On Jan 12, 2022 this sequence version replaced NM_001085507.1.
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR9219382.30305.1,
                                           SRR7652917.1085926.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849384,
                                           SAMN01164143 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-97                AL928955.17        35503-35599         c
            98-217              AL928955.17        32373-32492         c
            218-6604            AL928955.17        10381-16767         c
FEATURES             Location/Qualifiers
     source          1..6604
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 22.44 cM"
     gene            1..6604
                     /gene="Zbtb34"
                     /gene_synonym="Gm349; mKIAA1993"
                     /note="zinc finger and BTB domain containing 34"
                     /db_xref="GeneID:241311"
                     /db_xref="MGI:MGI:2685195"
     exon            1..97
                     /gene="Zbtb34"
                     /gene_synonym="Gm349; mKIAA1993"
                     /inference="alignment:Splign:2.1.0"
     exon            98..217
                     /gene="Zbtb34"
                     /gene_synonym="Gm349; mKIAA1993"
                     /inference="alignment:Splign:2.1.0"
     CDS             186..1742
                     /gene="Zbtb34"
                     /gene_synonym="Gm349; mKIAA1993"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="zinc finger and BTB domain-containing protein 34
                     isoform 1"
                     /protein_id="NP_001078976.1"
                     /db_xref="CCDS:CCDS38106.1"
                     /db_xref="GeneID:241311"
                     /db_xref="MGI:MGI:2685195"
                     /translation="MESTLEECNSRLRFVSGEMDNSSFIQFDVPEHSSTVLSQLNELR
                     LQGKLCDIIVHIQGQPFRAHKAVLAASSPYFRDHSALSTMSGLSISVIKNPSVFEQLL
                     SFCYTGRMSLQLKDVVSFLTAASFLQMQCVIDKCTQILESIHSKISVGDVDSVTIGAE
                     ENPESRNGVKDGSFFTNPVEISPPYCPQVRQPPVSSDLRMETTPNKALRSRLQEEGHS
                     DRGSSGSVSEYEIQIEGDHEQGDLLVRESQITEVKVKMEKSDRPSCSDSSSLGDDGYH
                     TEMVDGEQVVAVNVGAYGSVLQHAYPYSQTASQPSSVPEAFGGQTNSSPSRSMLSCFR
                     GRGARQKRALSVHLHSDLQGVVQGSDSEAMMNNPGYESSPRERSARGYWYPYNERLIC
                     IYCGKSFNQKGSLDRHMRLHMGITPFVCKFCGKKYTRKDQLEYHIRGHTDDKPFRCEV
                     CGKCFPFQGTLNQHLRKNHPGVTEGRGRMESPERTDMYVEQKLESDASASEMALDSRL
                     EMHTVSDAPD"
     exon            218..6604
                     /gene="Zbtb34"
                     /gene_synonym="Gm349; mKIAA1993"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6583..6588
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zbtb34"
                     /gene_synonym="Gm349; mKIAA1993"
                     /note="hexamer: AATAAA"
     polyA_site      6604
                     /gene="Zbtb34"
                     /gene_synonym="Gm349; mKIAA1993"
                     /note="major polyA site"
ORIGIN      
        1 gcggcagcgg gagcggcggg gaagggcctg gcgccggcgg cggcggcggc ggagggggcg
       61 ccgcgggcgg gcgatgtgaa cgcggcgcgc ggcccagctg acaaactgct gaatttagct
      121 tagtgaaggt caccaactga gcacagttaa gcttctaatg gttattttct gttgatgttg
      181 ctggcatgga aagcaccctg gaagaatgca attcaagatt acgtttcgtg tcgggagaaa
      241 tggacaacag cagtttcatt cagtttgatg tgcctgagca cagcagcacg gttctgagcc
      301 aactaaatga gctccgcctg caagggaagc tatgtgacat catcgtccac attcagggtc
      361 agcccttccg agcccacaaa gccgtcctcg cagccagctc cccgtatttc cgggaccatt
      421 cagcactgag cactatgagt ggcttgtcga tctctgtgat taagaacccc agcgtgtttg
      481 agcagttgct ctccttctgt tacactggaa ggatgtcctt gcagctgaag gatgttgtca
      541 gttttctgac cgcagccagc tttcttcaga tgcagtgtgt cattgacaag tgcacacaga
      601 tcctagagag catccactcg aagatcagcg tgggagacgt tgactctgtt accattggtg
      661 ctgaagagaa tcctgagagc cgaaatgggg tgaaagatgg cagcttcttc accaatcctg
      721 ttgaaatctc ccctccgtac tgccctcagg tacggcagcc tccagtcagc agtgatcttc
      781 ggatggagac aacccccaac aaagcccttc ggagccgctt gcaggaagag gggcactcag
      841 atcgggggag cagtgggagc gtgtctgagt atgagattca gatagaaggg gaccacgagc
      901 aaggggactt gttggtgaga gagagccaga tcactgaggt gaaagtgaag atggagaagt
      961 ctgaccggcc cagctgctcc gacagctctt ccctgggtga tgacggctac cacacggaga
     1021 tggttgatgg ggaacaagtt gtggccgtga atgtgggcgc ctatggctct gtgctccagc
     1081 atgcataccc ctactcccag acggcttcac agccttccag tgtgccagaa gcttttggag
     1141 gtcagaccaa ttccagtcca tccaggtcca tgctgagctg cttccgaggc cgtggggccc
     1201 gccagaagcg agctctgtct gttcacctgc acagtgacct gcagggtgtg gtgcaggggt
     1261 ctgacagtga agccatgatg aacaatcccg gttatgagag cagtccccgg gagaggagcg
     1321 ccagggggta ttggtaccca tacaacgaga ggttgatctg tatttactgt gggaagtcct
     1381 ttaaccagaa gggaagcctc gacaggcaca tgcggctgca tatggggatc accccctttg
     1441 tgtgcaagtt ctgtgggaag aagtacacgc gcaaggacca gctggagtat cacatccggg
     1501 gccacactga tgacaaacca ttccgatgcg aggtctgtgg gaagtgcttt ccattccagg
     1561 gtaccctcaa ccagcacctg cggaaaaacc acccgggggt caccgaaggc aggggtcgca
     1621 tggagtcccc cgaaagaaca gacatgtatg tggaacagaa actcgaaagt gatgcatcag
     1681 cctcagagat ggcactagat tcccgcctgg aaatgcacac agtgtctgat gcgcctgact
     1741 aaggagcacc tgcacagagc acagcaatca gcgcgtcctt gtgatctgct tggttgtaat
     1801 ctttgctttt ccccaccacc tggacatctc tcggtttttt tgctagtttc tctgaaggtt
     1861 ctgggtgggg acttcttgtg tttaccctcc cctctcctcc cctcccccaa ggagctcaaa
     1921 gcatgaaggg cagcatatcc agggaaaacg caggctgaca gtattccttt ttggctaaaa
     1981 tactttttgg cttctcccag ctctgccagt gattcagcta tgccaactgg ttgacctcac
     2041 gttctctgct aagagacagc actccctgtg ggtgctagcc ccagtgcatt ttcatggtga
     2101 gaggctagga tgctgtcagc tggtgcaaat gggtaatctt ttctaattta aaattacttt
     2161 tagggggtag ttagacaatt tatatatata tataataaag tggttattat atatatagta
     2221 tatatacatt ctcaaatttg agtttattct ggttgaggtg aatgtaagag gaatatataa
     2281 tttaatacaa tgtgaacaga gctctggctt tgtttcagcc ccgcctacta tgttagtttt
     2341 aacccttcgt ttcccttaca gaagaatgtc agtagacttt catatatagt aatcattgtg
     2401 tccaaatgca agcaaagcaa atcacagtgt tcatagctct gcttcataac aaacacataa
     2461 accaaatgcc ataaggttcc ttcaactgta gtgggaaacc attttggagt ttttgtttgt
     2521 tgtccaggta cactgggcag cttgcggtgc tgaccttcct acacagtgta ttgttacact
     2581 agccaacccc aaaggagcag tgcttttcaa ggtttttact ggcttataac tctaccttca
     2641 ttctgtactg tagaatcata cataccaggt aactaaatcg ctccaccttg agttagtact
     2701 ccgactaaag gacaggaatt tgtagagctt gtctacaaaa ttctccaagc agtgttgtgg
     2761 ttttgttatt ttgttttctt tttttttttc tctcaaacag ccagttcagg tgcacagcaa
     2821 cttttttcta tgcagttccc agggaaactg cagaacttgg aatttgtact ttttgtaaag
     2881 ctatatactc tacgggaatt gcaagcaata tatctatctt ggtattgtgt gtgctaatga
     2941 gagccccaga ggctccccac tctcagtgtt tcctgcttaa agaaaaaagt cagaactctc
     3001 tctaagatcc tctgtgtgtc accagatctg tgtgtgtgtc tcacattttt ggtcatgtgg
     3061 tgctattttt atgttaacta tcttttaggt cagtatcggt ctagaaaatg tgaaacctac
     3121 cagtagtact gatttagtta ctttcctctc aagttcacag cttggaaaga aacctcaaag
     3181 gcatgtgctg gcaaactggt tactgtctga gttgtgtctg gtcagtgctt tggagactgt
     3241 ctctgcttgc tgttagattc atatacacca acaggcttca caaatggctc tggtgctgtg
     3301 gactcaggca gagagggcag tttagtcatg cagctggctg ccggggacag cggcgctcta
     3361 gtctctgcct gagaacctga gcctgagaca tggactcaaa ccaacagacc cagaatctga
     3421 ggaccaacct caaaggctag gagctaagga atacagaaat agatgtttgc tggtctgtca
     3481 tgcttttgtg gctcttaaga taccaagaac aatgggtttg gggggaaaac tttttcgttt
     3541 tttgtttgtt tgtttgtttg tttgtttgtt tttgagaaaa agtttgatcc cagcccttgt
     3601 gtgtagcagc cccggtggcg gctcagtagc acctccttag cacacaggat ctgctcacat
     3661 gtgaactcgc ctcacctcag tgttaactcc tgtagatgac taatcccgct gctcctggag
     3721 cagcttttgc taatcgggta tacggtatgc cttttcctcg tcaaactgcc taagtcggga
     3781 tctcttcttt ccctggagca tttgttcagc cgagaaagct gagcgcctca aggggaggct
     3841 gggccccaag tgtttaccta cttaagtgtg ttctgaggct tcaggtaaat gtctgtgatt
     3901 ttcattttcc ttacatgatt gcgtttgctt ttgatttttt tttaattaaa tgcaaaaact
     3961 tttttttttc gtattgtgat atcaattaag tttgtgacaa gaaaggccct aaatctaagg
     4021 atgtgagaca tcgagctcag ggaaggagcc tccttttcac tgaggcctgg ggccttctga
     4081 ggagcttcca gagctttctg tggtgaggct ggcacactcg ggcagcgtgt ccatgtcctg
     4141 gctcttgtca ctgtctgttg gaactcacag acatggagtt cttgtgtttg tcaacttgtt
     4201 tagctggttt gagtttacca aagagtgact tatccaaaat tgtctttgac aaaaatatac
     4261 attgctttga ttgtacagtt caggttcaaa cattgtaatg ggactgttaa agggcagaaa
     4321 accgatttga gttttaaatg atcatgattc cgtgttttac aaattgcgct tgctcccatt
     4381 cgtgttgcta acactttacc ctctccactg ctagcagtgt taagaatgaa ttctcaagcc
     4441 ataacacagt actgtaaagt tcacagggct tcgaggggga cagcgcccag gccagcacag
     4501 cgctgcatag cctgtctgca cagtcaccct aggtgcctac cggtgggcat ggctaccaag
     4561 ggcccactgt gcagatagcg cagcagcggt taattgtgcc tagccacatg aggatgttcc
     4621 aggagagaca gcatagccac ctagcaggcc tctctcccca aagctcactg tgcaactcct
     4681 tgtggacagc aaacctgtcc ctgtacagtt gtaggttagg tctctcacta tagccgatgc
     4741 acaagtccac taagataaac aatatgtgaa gacatctttt gcagtgaagt atgtcctgct
     4801 ttcatacagg cctgtgcgtg attgagtctc ttctcagcta cctttccatg ttagacaatg
     4861 tgaagacagc cacagcgccc ttccctgcaa cattacccca ttgcacaaac tgtgaagatg
     4921 ttttatactt ttgctaacac ttgtggtttt caatctttgt ttgttctcat cagtactctg
     4981 ccctcttgtt tctactaaaa ctgtaaatac atttaggaac catttgtaaa tacagttaca
     5041 aagatgagtt catcttcctg gtcagtggaa aagcctccca gtcaattggc tctgccttgg
     5101 catttttttg ttgttggtgg gtttctctct ctctctctct ctctctctct ctctctctct
     5161 ccttctctct ccctctctct ccctccctcc tctcccttcc cttcctccct ctcttttctt
     5221 tctccctctc tccttccttc cttccctccc tccctctccc ccctctctct ctctctctct
     5281 tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtatact gttggttcac
     5341 tgttaaacag aatatactgt agaactaaat tggtaatttt taaatctccc agagatctat
     5401 aaatgtatgc ctctcttaat gatggcaagt ataacccacc tctgttttac aggcatgcat
     5461 ttgtgtgtgt gtgtgtgtgt gtgtgtttaa tttttaacaa cctagattct ggggagaatc
     5521 cgaaagaaca tgacgcaagg gcggggggac gtctgtgtga gtgagctctg ccttgggttg
     5581 ctgtgtttta ttctaagctt tccgcttgtt actgctatgt gtttgtagtt ctgttgttgt
     5641 tagattctat aatggtttcc tgtgaagccg ccactgaaag ggactcaaat atgcaacatc
     5701 taaactattt tccaagggct catgcccctt gaatggtgct tttagcctgg tcagggttat
     5761 ttattaaatt ttatatatga aagtactggg gaattatgta aactctttat acaagactat
     5821 ctagttctta catcataggt ttcattactc agcgcagctg aactgaaagt tcagggaagt
     5881 cattcacttt gttccagatt tgtaatggtc gtcacacatg tcgtcttcag taagtgccag
     5941 agttcccact gttcctgcca gggcttgcca actccaggtg ctcccctggg tctggtacag
     6001 acagggctat tgctgctcct ggagcaagct ctgctcactg ccctgagtgg cagcctgagc
     6061 ttacagacct ctcaccgccc tgcccttcag tgacaagcat gctgtgaatg tggcctcagg
     6121 acttggagac caagctccag gctgctgccc tgagtagagc aagaggtaaa ctcccctgcc
     6181 tcccctgaga acgaccgttt tcctaatgtg aaatcacctc tcaccacttt agcagtaggg
     6241 ctaactagtc ttctgttaca aatggctgag caatttgaat gacttcacat ggtgtcatta
     6301 tcttgcaata taaactggta acctcaacgc cacacttcat caccacgtga agtaaatgaa
     6361 gctagctaag cggatgctgt gtcactagta acttgccatt aagggttatt ttatagcatg
     6421 aattgaagac tatttattca aatgatattt tactcgtatt cattttgctt taggtttgtg
     6481 acatgaatat ttcagtgctg cttcatttcg ttctgaattc ttgtttcttg cttgtaaatg
     6541 gcttttttat ggtaataaat tcgatggaaa ttgctgtttg taaataaaaa tgctgctaga
     6601 gcaa
//
