LOCUS       NM_020625               2680 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Mus musculus zinc finger and BTB domain containing 22 (Zbtb22),
            mRNA.
ACCESSION   NM_020625
VERSION     NM_020625.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2680)
  AUTHORS   Liu,N., Yang,X., Guo,J., Zhang,L., Huang,S., Chen,J., Huang,J.,
            Chen,Y., Cui,T., Zheng,Y., Li,T., Tang,K., Zhong,Y., Duan,S.,
            Yu,L., Tang,Y., Zheng,D., Pan,H. and Gao,Y.
  TITLE     Hepatic ZBTB22 promotes hyperglycemia and insulin resistance via
            PEPCK1-driven gluconeogenesis
  JOURNAL   EMBO Rep 24 (6), e56390 (2023)
   PUBMED   37154299
  REMARK    GeneRIF: Hepatic ZBTB22 promotes hyperglycemia and insulin
            resistance via PEPCK1-driven gluconeogenesis.
REFERENCE   2  (bases 1 to 2680)
  AUTHORS   Medeiros de Araujo,J.A., Barao,S., Mateos-White,I., Espinosa,A.,
            Costa,M.R., Gil-Sanz,C. and Muller,U.
  TITLE     ZBTB20 is crucial for the specification of a subset of callosal
            projection neurons and astrocytes in the mammalian neocortex
  JOURNAL   Development 148 (16) (2021)
   PUBMED   34351428
REFERENCE   3  (bases 1 to 2680)
  AUTHORS   Logunova,N., Korotetskaya,M., Polshakov,V. and Apt,A.
  TITLE     The QTL within the H2 Complex Involved in the Control of
            Tuberculosis Infection in Mice Is the Classical Class II H2-Ab1
            Gene
  JOURNAL   PLoS Genet 11 (11), e1005672 (2015)
   PUBMED   26618355
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2680)
  AUTHORS   Wiese,C.B., Ireland,S., Fleming,N.L., Yu,J., Valerius,M.T.,
            Georgas,K., Chiu,H.S., Brennan,J., Armstrong,J., Little,M.H.,
            McMahon,A.P. and Southard-Smith,E.M.
  TITLE     A genome-wide screen to identify transcription factors expressed in
            pelvic Ganglia of the lower urinary tract
  JOURNAL   Front Neurosci 6, 130 (2012)
   PUBMED   22988430
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2680)
  AUTHORS   Guo,G., Huss,M., Tong,G.Q., Wang,C., Li Sun,L., Clarke,N.D. and
            Robson,P.
  TITLE     Resolution of cell fate decisions revealed by single-cell gene
            expression analysis from zygote to blastocyst
  JOURNAL   Dev Cell 18 (4), 675-685 (2010)
   PUBMED   20412781
REFERENCE   6  (bases 1 to 2680)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   7  (bases 1 to 2680)
  AUTHORS   Abe,K., Yuzuriha,M., Sugimoto,M., Ko,M.S., Brathwaite,M., Waeltz,P.
            and Nagaraja,R.
  TITLE     Gene content of the 750-kb critical region for mouse embryonic
            ectoderm lethal tcl-w5
  JOURNAL   Mamm Genome 15 (4), 265-276 (2004)
   PUBMED   15112104
REFERENCE   8  (bases 1 to 2680)
  AUTHORS   Allcock,R.J., Martin,A.M. and Price,P.
  TITLE     The mouse as a model for the effects of MHC genes on human disease
  JOURNAL   Immunol Today 21 (7), 328-332 (2000)
   PUBMED   10871872
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY011334.1 and BC052154.1.
            
            On May 25, 2007 this sequence version replaced NM_020625.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC052154.1, AK157161.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-369               BY011334.1         2-370
            370-2680            BC052154.1         317-2627
FEATURES             Location/Qualifiers
     source          1..2680
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 17.98 cM"
     gene            1..2680
                     /gene="Zbtb22"
                     /gene_synonym="1110008J20Rik; Bing1; Zfp297"
                     /note="zinc finger and BTB domain containing 22"
                     /db_xref="GeneID:81630"
                     /db_xref="MGI:MGI:1931870"
     exon            1..98
                     /gene="Zbtb22"
                     /gene_synonym="1110008J20Rik; Bing1; Zfp297"
                     /inference="alignment:Splign:2.1.0"
     exon            99..2607
                     /gene="Zbtb22"
                     /gene_synonym="1110008J20Rik; Bing1; Zfp297"
                     /inference="alignment:Splign:2.1.0"
     CDS             165..2081
                     /gene="Zbtb22"
                     /gene_synonym="1110008J20Rik; Bing1; Zfp297"
                     /note="zinc finger protein 297"
                     /codon_start=1
                     /product="zinc finger and BTB domain-containing protein
                     22"
                     /protein_id="NP_065650.1"
                     /db_xref="CCDS:CCDS28634.1"
                     /db_xref="GeneID:81630"
                     /db_xref="MGI:MGI:1931870"
                     /translation="MEPSALSPSGATLPLPLSLAPPPLPLPAAAVVHVSFPEVTSALL
                     ESLNQQRLQGQLCDVSIRVQGREFRAHRAVLAASSPYFHDQVLLKGMTSISLPSVMDP
                     GAFETVLASAYTGRLSMAAADIVNFLTVGSVLQMWHIVDKCTELLREGRSAATTTTVT
                     TAAAPSVSVPCASVPSGNGGTVAPATVGSVRSHTSSRASENQSPSSSNYFSPRESTDF
                     SSTSQDAFVASAAGSGNRRDGGPVFPAPVVGSAGTTSGKLLLEADELCDDGGDGRGAV
                     APGAGLRRSNCMPASAVPQKHWVYVKQARNCPAPASLVHQDPDLEDEEEEEDLVLTCE
                     DDEDEEMGGGSGVPAGGEPEATLSISDVRTLTEPADKGEEQVNFCESSNDFGPYEGGG
                     AGAGLDDPGGPTPSSYALTHPPRPLLPLDVPGNQILVFPSSSSQAPGQPPGNTAEHGA
                     VTLGGTSAVGLGIPSGSGGAPGGTGNSDGNKIFLCHCGKAFSHKSMRDRHVNMHLNLR
                     PFDCPVCNKKFKMKHHLTEHMKTHTGLKPYECSVCAKKFMWRDSFMRHRGHCERRHRM
                     GVGGVGSGPGPGPGPGTPSGPALQPKRESSTVGGGSGDEANSATPPSHRRVWSPPSVH
                     KVEMDFSGGGGAAH"
     regulatory      2583..2588
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zbtb22"
                     /gene_synonym="1110008J20Rik; Bing1; Zfp297"
                     /note="hexamer: ATTAAA"
     polyA_site      2607
                     /gene="Zbtb22"
                     /gene_synonym="1110008J20Rik; Bing1; Zfp297"
                     /note="major polyA site"
ORIGIN      
        1 ggaaggcgga gggagtcggc acaagatggc ggcgggaggg gctggggctg cggctctggt
       61 cgcggagtga gggggggggc ccgggggcgc gcggccagag acccccccgg ccgccctctt
      121 ctttcctttg ttcctgtggc tgggggggta tctccttcca cagcatggag ccgtctgctc
      181 tgtcacccag tggggccaca ctcccactgc ctctgtcact ggctccaccg ccactgcctc
      241 tgccggcagc tgcagtggta cacgtgtcct tccctgaggt gaccagtgcc ctcctggaat
      301 ccctcaacca gcagcggctc cagggtcagc tctgtgatgt gtccatccgc gtgcagggac
      361 gggagttccg cgctcacagg gccgtcttgg ctgcctcctc tccttacttc cacgaccagg
      421 tcctactgaa aggcatgact tccatttccc tgccaagcgt catggaccca ggcgcttttg
      481 agactgtcct ggcctcagct tacacgggcc gcctcagcat ggctgctgcg gacattgtca
      541 acttcctcac agtggggtcg gtcctccaga tgtggcacat tgtggataag tgcactgaac
      601 tccttcggga gggtcgatcc gcagccacta caaccactgt cactactgct gcagccccct
      661 ctgtctctgt cccttgtgcc agtgtcccat cagggaatgg gggcactgtc gcccctgcca
      721 ccgtaggctc tgtccgttcc catacctcca gcagggccag tgagaatcag tctcccagca
      781 gtagcaacta cttcagcccc cgggagtcga ctgatttctc ctctacctcc caggatgcat
      841 ttgtggcctc agcagcaggt agtgggaacc gtcgggatgg tggcccggtg ttcccagccc
      901 ctgtggttgg cagtgcgggt accacctccg ggaagttgct gctggaggcc gatgagctat
      961 gcgatgacgg tggggatggg agaggggccg tggcccccgg ggctgggctc cggaggtcta
     1021 actgcatgcc tgccagtgca gtgccacaga aacactgggt gtatgtgaag caagctagaa
     1081 attgccctgc accagcctcc ctggtccacc aagaccccga tctagaagat gaggaagagg
     1141 aggaagatct ggtgttgact tgtgaggatg atgaggatga agaaatggga ggcggctctg
     1201 gggttcctgc agggggagag cccgaggcta ccctcagtat cagtgatgtt cggaccttga
     1261 ccgagcctgc agacaagggg gaagagcagg tcaacttctg tgaatcctcc aatgactttg
     1321 gcccctatga gggtgggggc gctggggcag ggcttgatga ccccggagga cccacccctt
     1381 cctcctatgc cctcacccac cctccacgac ccctccttcc attggatgtg ccgggcaacc
     1441 agatcttggt tttcccatcc tcctcttcac aggctccagg ccagccacca gggaacacag
     1501 ctgagcacgg ggcagtgacc ctcgggggca cctctgcggt ggggctgggc ataccaagtg
     1561 gctctggtgg ggctcctgga gggacaggca acagcgacgg gaataagatc tttctgtgcc
     1621 actgtgggaa ggctttctca cataagagca tgcgggaccg gcacgtgaat atgcatctca
     1681 acctgcgacc ctttgactgc cccgtgtgca acaaaaagtt caagatgaaa caccacctga
     1741 ccgagcacat gaagacacac acgggcctca agccgtacga atgcagtgtc tgcgccaaga
     1801 agttcatgtg gcgggacagt ttcatgcgtc accggggaca ctgtgagcgt cggcaccgga
     1861 tgggtgtggg tggggtcgga tctggaccgg gtcctggacc tggacccggg acaccttctg
     1921 ggccagcatt gcaacccaag agggagtctt ccacagtggg tgggggcagt ggcgatgagg
     1981 caaattcggc cacgcccccg tcccataggc gtgtctggtc cccacccagc gtgcacaaag
     2041 tggagatgga tttcagtggg ggtggaggtg cagcacactg aagagcaggc aattggggag
     2101 cttagtctaa gagcaatggc tcccggggtt tcccccacca aacagtcttc ccttacctcg
     2161 gtggacttgt atatattcta gagaagggcg tgggttgcac cgtcgccagc ccgttccatt
     2221 cctcagcccc ttcctcgaga tctctggaac taagctgtgt ttttgctttt cccctgagca
     2281 caccagagcc ccaccttcac ggagtagtgc caacaaggtg ggggaatgga aaagggacct
     2341 tttgagcatc ctagagtcac agagccaaca gtcaggttgt gctagtttgt gcctgaagtc
     2401 tgtgtttgtg ttgtgggaca aggcctttga gtcttaacga ttgtcctttc tcctcttgaa
     2461 ggatacgccc cttatttctg tactacccca cccttgccat ggggatccca aattgggttg
     2521 tcatgaaagt gggtggacac aaggtgggag ccgcgtagta taggtcttaa tttttaacgg
     2581 tgattaaaat atttattggt cacttcaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     2641 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
//
